Symbol:
Plscr5
Name:
phospholipid scramblase family, member 5
RGD ID:
1564500
Description:
Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be active in plasma membrane. Orthologous to human PLSCR5 (phospholipid scramblase family member 5); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC501036; phospholipid scramblase family member 5; RGD1564500; similar to phospholipid scramblase 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 101,597,207 - 101,618,571 (+) NCBI GRCr8 mRatBN7.2 8 92,717,479 - 92,738,843 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 92,722,600 - 92,738,299 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 8 98,400,883 - 98,416,577 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 96,600,134 - 96,615,828 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 94,432,845 - 94,448,560 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 8 99,558,279 - 99,579,791 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 99,568,958 - 99,579,255 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 8 99,042,074 - 99,063,372 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 8 97,143,459 - 97,159,158 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 8 92,241,712 - 92,257,400 (+) NCBI Celera Cytogenetic Map 8 q31 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Plscr5 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 101,597,207 - 101,618,571 (+) NCBI GRCr8 mRatBN7.2 8 92,717,479 - 92,738,843 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 92,722,600 - 92,738,299 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 8 98,400,883 - 98,416,577 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 96,600,134 - 96,615,828 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 94,432,845 - 94,448,560 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 8 99,558,279 - 99,579,791 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 99,568,958 - 99,579,255 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 8 99,042,074 - 99,063,372 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 8 97,143,459 - 97,159,158 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 8 92,241,712 - 92,257,400 (+) NCBI Celera Cytogenetic Map 8 q31 NCBI
PLSCR5 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 3 146,576,555 - 146,605,346 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 3 146,576,555 - 146,605,346 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 3 146,294,342 - 146,323,133 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 3 147,786,315 - 147,806,693 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 3 144,720,660 - 144,741,039 (-) NCBI Celera Cytogenetic Map 3 q24 NCBI HuRef 3 143,680,464 - 143,700,842 (-) NCBI HuRef CHM1_1 3 146,266,683 - 146,287,061 (-) NCBI CHM1_1 T2T-CHM13v2.0 3 149,331,731 - 149,360,509 (-) NCBI T2T-CHM13v2.0
Plscr5 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 9 92,068,569 - 92,094,589 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 9 92,074,989 - 92,091,825 (+) Ensembl GRCm39 Ensembl GRCm38 9 92,186,516 - 92,212,536 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 9 92,192,936 - 92,209,772 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 9 92,087,774 - 92,104,536 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 9 92,087,774 - 92,104,536 (+) NCBI MGSCv36 mm8 Celera 9 91,780,517 - 91,797,373 (+) NCBI Celera Cytogenetic Map 9 E3.3 NCBI cM Map 9 48.33 NCBI
Plscr5 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955474 10,855,888 - 10,904,450 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955474 10,855,958 - 10,903,801 (+) NCBI ChiLan1.0 ChiLan1.0
PLSCR5 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 2 144,461,879 - 144,490,694 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 3 144,466,610 - 144,495,425 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 3 143,593,413 - 143,628,126 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 3 151,176,200 - 151,210,799 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 3 151,176,253 - 151,212,156 (-) Ensembl panpan1.1 panPan2
PLSCR5 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 23 41,709,662 - 41,739,638 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 23 41,681,017 - 41,733,150 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 23 41,574,886 - 41,604,840 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 23 42,327,939 - 42,357,931 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 23 42,331,540 - 42,357,955 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 23 41,915,765 - 41,945,917 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 23 41,990,888 - 42,021,009 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 23 42,234,122 - 42,264,264 (-) NCBI UU_Cfam_GSD_1.0
Plscr5 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405602 81,019,261 - 81,046,315 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936519 8,694,575 - 8,712,077 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936519 8,688,210 - 8,712,104 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
PLSCR5 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 13 86,928,254 - 86,949,019 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 13 86,920,326 - 86,954,257 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 13 94,560,866 - 94,587,178 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
PLSCR5 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 15 44,096,245 - 44,134,975 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 15 44,106,757 - 44,121,238 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666041 16,985,249 - 17,012,992 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Plscr5 (Heterocephalus glaber - naked mole-rat)
.
Predicted Target Of
Count of predictions: 11 Count of miRNA genes: 8 Interacting mature miRNAs: 11 Transcripts: ENSRNOT00000073400 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
12879878 Bw183 Body weight QTL 183 0.001 body mass (VT:0001259) body weight (CMO:0000012) 8 43296169 98968765 Rat 1300177 Cm2 Cardiac mass QTL 2 3.65 heart mass (VT:0007028) heart weight (CMO:0000017) 8 54259986 100382532 Rat 1549909 Stresp11 Stress response QTL 11 6.83 0.0019 stress-related behavior trait (VT:0010451) number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960) 8 73473045 118473045 Rat 1549908 Neudeg1 Neurodegradation QTL 1 5.5 0 nervous system integrity trait (VT:0010566) logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986) 8 30188867 94457446 Rat 12879879 Cm99 Cardiac mass QTL 99 0.001 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 8 43296169 98968765 Rat 1554321 Bmd3 Bone mineral density QTL 3 7.9 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 8 40952565 123900184 Rat 9590292 Uminl3 Urine mineral level QTL 3 3.62 0.001 urine mineral amount (VT:0015086) urine electrolyte level (CMO:0000593) 8 71888757 116888757 Rat 1578769 Uae31 Urinary albumin excretion QTL 31 3.3 0.001 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 8 30848154 101699754 Rat 12879880 Cm100 Cardiac mass QTL 100 0.001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 8 43296169 98968765 Rat 12879881 Cm101 Cardiac mass QTL 101 0.001 heart right ventricle mass (VT:0007033) heart right ventricle weight to body weight ratio (CMO:0000914) 8 43296169 98968765 Rat 12879882 Am8 Aortic mass QTL 8 0.001 aorta mass (VT:0002845) aorta weight to aorta length to body weight ratio (CMO:0002722) 8 43296169 98968765 Rat 12879883 Kidm65 Kidney mass QTL 65 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 8 43296169 98968765 Rat 8693654 Alc32 Alcohol consumption QTL 32 2 0.755 drinking behavior trait (VT:0001422) calculated ethanol drink intake rate (CMO:0001615) 8 88612425 107550209 Rat 1358912 Bw51 Body weight QTL 51 2.95 body mass (VT:0001259) body weight (CMO:0000012) 8 51351728 107062046 Rat 1578765 Klgr1 Kidney lesion grade QTL 1 3.3 0.0001 kidney morphology trait (VT:0002135) organ lesion measurement (CMO:0000677) 8 30848154 101699754 Rat 1300171 Bp184 Blood pressure QTL 184 3.66 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 8 70513503 118219066 Rat 1578755 Pur5 Proteinuria QTL 5 3.3 0.0001 urine total protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 8 30848154 101699754 Rat 2313400 Anxrr25 Anxiety related response QTL 25 aggression-related behavior trait (VT:0015014) tameness/aggressiveness composite score (CMO:0002136) 8 89265192 114019816 Rat 2303171 Bp331 Blood pressure QTL 331 5.57 0.005 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 61290298 119084929 Rat 8662823 Vetf5 Vascular elastic tissue fragility QTL 5 1.9 artery integrity trait (VT:0010639) patent ductus arteriosus score (CMO:0002566) 8 28242912 99525068 Rat 2293697 Bmd39 Bone mineral density QTL 39 femur strength trait (VT:0010010) femur total energy absorbed before break (CMO:0001677) 8 54043744 98968765 Rat 631210 Bw3 Body weight QTL3 5.9 mesenteric fat pad mass (VT:0010427) mesenteric fat pad weight to body weight ratio (CMO:0000654) 8 69349194 112783834 Rat 1358896 Bp262 Blood pressure QTL 262 2.89 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 27205715 99103503 Rat 731182 Uae24 Urinary albumin excretion QTL 24 6.4 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 8 19331152 93965294 Rat 1331837 Bw23 Body weight QTL 23 4.19 0.00007 body mass (VT:0001259) body weight (CMO:0000012) 8 46531722 99083736 Rat 1331838 Niddm61 Non-insulin dependent diabetes mellitus QTL 61 3.53 0.0004 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 8 36469535 99083736 Rat 8694446 Bw170 Body weight QTL 170 12.07 0.001 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 8 71888757 116888757 Rat 631650 Stl6 Serum triglyceride level QTL 6 4 0.0019 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 8 10378157 112202585 Rat 631653 Bp125 Blood pressure QTL 125 3.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 66142385 111142385 Rat 1581557 Eae16 Experimental allergic encephalomyelitis QTL 16 3.8 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 8 8462195 110921472 Rat 1358906 Bp253 Blood pressure QTL 253 4 0.0004 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 40713066 93965294 Rat 1358907 Cm40 Cardiac mass QTL 40 1.89 heart mass (VT:0007028) heart weight to body weight ratio (CMO:0000074) 8 27205715 99103503 Rat 2303570 Gluco48 Glucose level QTL 48 2 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 8 49805831 94805831 Rat 70197 BpQTLcluster8 Blood pressure QTL cluster 8 3.482 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 46531639 119088626 Rat 2316950 Scl66 Serum cholesterol level QTL 66 4.1 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 8 30848259 105647037 Rat 2300181 Bmd55 Bone mineral density QTL 55 5.7 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 8 76468691 121468691 Rat 10402857 Bp380 Blood pressure QTL 380 0.95 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 53968765 98968765 Rat 1358892 Kidm26 Kidney mass QTL 26 3.69 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 8 27205715 99103503 Rat 2301402 Bp316 Blood pressure QTL 316 0.005 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 53968765 98968765 Rat 631664 Hcar3 Hepatocarcinoma resistance QTL 3 2.9 0.0005 liver integrity trait (VT:0010547) volume of individual liver tumorous lesion (CMO:0001078) 8 54237644 99103503 Rat 8694200 Abfw4 Abdominal fat weight QTL 4 9.07 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 8 71888757 116888757 Rat 8694392 Bw161 Body weight QTL 161 8.06 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 8 71888757 116888757 Rat 61437 Cia6 Collagen induced arthritis QTL 6 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 8 82460758 122812818 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
4
3
85
12
15
5
13
5
29
17
84
3
19
10
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Ensembl Acc Id:
ENSRNOT00000073400 ⟹ ENSRNOP00000066419
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 8 92,722,600 - 92,738,299 (+) Ensembl Rnor_6.0 Ensembl 8 99,568,958 - 99,579,255 (+) Ensembl
RefSeq Acc Id:
NM_001191999 ⟹ NP_001178928
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 101,597,207 - 101,618,571 (+) NCBI mRatBN7.2 8 92,717,479 - 92,738,843 (+) NCBI Rnor_6.0 8 99,563,556 - 99,579,255 (+) NCBI Rnor_5.0 8 99,042,074 - 99,063,372 (+) NCBI Celera 8 92,241,712 - 92,257,400 (+) NCBI
Sequence:
ATGGCTTCTAAAGATTCCCAGAACCAAAAGCCTAGAAGTCTGCCTGGTTTTCTTCCTCGAGCTACAAACCCAGATCAAAACTCTCAAGAGGCTTCTTCCAATCCCGGGAAACAAACAAGGCAGCAGCC CCATGTCTCTCAGCCAAGCAGTTTCCTGCCAACAGCCATTCTCCCTCCTGGTCTAGAGTATCTAAGCCAGCTGGACCTGATAATCATCCATCAGCAGGTAGAACTTCTTGGGATGATACTCGGCACTG AGACCTCCAACAAATATGAGATCAAAAACAGCTCGGGACAAAGAATTTACTTTGCAGTGGAAGAAAGCATCTGTTTTAATCGTAATGTGTGCTCCACGCTGCGAGCCTGCACCCTGAGGATCACAGAC AACTCGGGTCGAGAGGTGATTACAGTGAACAGGCCCCTAAGGTGTAACAGCTGCTGGTGCCCTTGCTACCTACAAGAGCTAGAAATCCAAGCCCCCCCTGGGACTATAGTTGGTTTTGTTGCACAGAA GTGGGACCCCTTTCAGCCCAAATTCACAATCCAAAATGCAAACAAAGAAGATATTTTGAAAATCGTTGGTCCTTGTACAACCTGTGGCTGCTTTGGCGATGTGGACTTTGAGGTGAAAACTGTTGATG AAAAGGTTACAATTGGGAAGATCTCCAAGTACTGGTCGGGATTTGTCAACGACGTGTTCACAAATGCTGACAACTTTGGGATCCATGTTCCTGAAGATCTCGATGTGACACTCAAAGCAGCCATGATT GGTGCTTGCTTTCTCTTTGATTTTATGTTCTTTGAACATTCGCTTGCTGGATTATAA
hide sequence
RefSeq Acc Id:
NP_001178928 ⟸ NM_001191999
- UniProtKB:
M0RA77 (UniProtKB/TrEMBL)
- Sequence:
MASKDSQNQKPRSLPGFLPRATNPDQNSQEASSNPGKQTRQQPHVSQPSSFLPTAILPPGLEYLSQLDLIIIHQQVELLGMILGTETSNKYEIKNSSGQRIYFAVEESICFNRNVCSTLRACTLRITD NSGREVITVNRPLRCNSCWCPCYLQELEIQAPPGTIVGFVAQKWDPFQPKFTIQNANKEDILKIVGPCTTCGCFGDVDFEVKTVDEKVTIGKISKYWSGFVNDVFTNADNFGIHVPEDLDVTLKAAMI GACFLFDFMFFEHSLAGL
hide sequence
Ensembl Acc Id:
ENSRNOP00000066419 ⟸ ENSRNOT00000073400
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2010-05-05
Plscr5
phospholipid scramblase family, member 5
RGD1564500
similar to phospholipid scramblase 1
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2008-04-30
RGD1564500
similar to phospholipid scramblase 1
RGD1564500_predicted
similar to phospholipid scramblase 1 (predicted)
'predicted' is removed
2292626
APPROVED
2006-03-07
RGD1564500_predicted
similar to phospholipid scramblase 1 (predicted)
LOC501036
similar to phospholipid scramblase 1
Symbol and Name status set to approved
1299863
APPROVED
2006-02-09
LOC501036
similar to phospholipid scramblase 1
Symbol and Name status set to provisional
70820
PROVISIONAL