PLSCR5 (phospholipid scramblase family member 5) - Rat Genome Database

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Gene: PLSCR5 (phospholipid scramblase family member 5) Canis lupus familiaris
Analyze
Symbol: PLSCR5
Name: phospholipid scramblase family member 5
RGD ID: 12341833
Description: ENCODES a protein that exhibits phospholipid scramblase activity (inferred); INVOLVED IN plasma membrane phospholipid scrambling (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC611511
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12341,709,662 - 41,739,638 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2341,681,017 - 41,733,150 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2341,574,886 - 41,604,840 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02342,327,939 - 42,357,931 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2342,331,540 - 42,357,955 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12341,915,765 - 41,945,917 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02341,990,888 - 42,021,009 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02342,234,122 - 42,264,264 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLSCR5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12341,709,662 - 41,739,638 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2341,681,017 - 41,733,150 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2341,574,886 - 41,604,840 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02342,327,939 - 42,357,931 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2342,331,540 - 42,357,955 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12341,915,765 - 41,945,917 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02341,990,888 - 42,021,009 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02342,234,122 - 42,264,264 (-)NCBIUU_Cfam_GSD_1.0
PLSCR5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383146,576,555 - 146,605,346 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3146,576,555 - 146,605,346 (-)EnsemblGRCh38hg38GRCh38
GRCh373146,294,342 - 146,323,133 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363147,786,315 - 147,806,693 (-)NCBINCBI36Build 36hg18NCBI36
Celera3144,720,660 - 144,741,039 (-)NCBICelera
Cytogenetic Map3q24NCBI
HuRef3143,680,464 - 143,700,842 (-)NCBIHuRef
CHM1_13146,266,683 - 146,287,061 (-)NCBICHM1_1
T2T-CHM13v2.03149,331,731 - 149,360,509 (-)NCBIT2T-CHM13v2.0
Plscr5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39992,068,569 - 92,094,589 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl992,074,989 - 92,091,825 (+)EnsemblGRCm39 Ensembl
GRCm38992,186,516 - 92,212,536 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl992,192,936 - 92,209,772 (+)EnsemblGRCm38mm10GRCm38
MGSCv37992,087,774 - 92,104,536 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36992,087,774 - 92,104,536 (+)NCBIMGSCv36mm8
Celera991,780,517 - 91,797,373 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map948.33NCBI
Plscr5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88101,597,207 - 101,618,571 (+)NCBIGRCr8
mRatBN7.2892,717,479 - 92,738,843 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl892,722,600 - 92,738,299 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx898,400,883 - 98,416,577 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0896,600,134 - 96,615,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0894,432,845 - 94,448,560 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0899,558,279 - 99,579,791 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl899,568,958 - 99,579,255 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0899,042,074 - 99,063,372 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4897,143,459 - 97,159,158 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera892,241,712 - 92,257,400 (+)NCBICelera
Cytogenetic Map8q31NCBI
Plscr5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547410,855,888 - 10,904,450 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547410,855,958 - 10,903,801 (+)NCBIChiLan1.0ChiLan1.0
PLSCR5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22144,461,879 - 144,490,694 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13144,466,610 - 144,495,425 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03143,593,413 - 143,628,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13151,176,200 - 151,210,799 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3151,176,253 - 151,212,156 (-)Ensemblpanpan1.1panPan2
Plscr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560281,019,261 - 81,046,315 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365198,694,575 - 8,712,077 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365198,688,210 - 8,712,104 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLSCR5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1386,928,254 - 86,949,019 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11386,920,326 - 86,954,257 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21394,560,866 - 94,587,178 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLSCR5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11544,096,245 - 44,134,975 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1544,106,757 - 44,121,238 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604116,985,249 - 17,012,992 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plscr5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473023,549,667 - 23,565,050 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473023,551,467 - 23,565,050 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PLSCR5
419 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 12 4 12 6
Below cutoff 4 5 10 6 6 6 2 6 8 4 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014106815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038432609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038432610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038432611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038507907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038507908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038571148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038571149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038571150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038635341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038635342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_849187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000043736   ⟹   ENSCAFP00000038735
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2341,681,017 - 41,733,150 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000087466   ⟹   ENSCAFP00000064672
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2341,681,017 - 41,733,150 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845037775   ⟹   ENSCAFP00845029600
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2342,331,540 - 42,357,955 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845037847   ⟹   ENSCAFP00845029655
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2342,331,540 - 42,351,393 (-)Ensembl
RefSeq Acc Id: XM_014106815   ⟹   XP_013962290
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12341,709,662 - 41,733,000 (-)NCBI
Dog10K_Boxer_Tasha2341,574,886 - 41,598,257 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038432609   ⟹   XP_038288537
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02342,327,939 - 42,351,307 (-)NCBI
RefSeq Acc Id: XM_038432610   ⟹   XP_038288538
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02342,327,939 - 42,357,931 (-)NCBI
RefSeq Acc Id: XM_038432611   ⟹   XP_038288539
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02342,327,939 - 42,351,344 (-)NCBI
RefSeq Acc Id: XM_038457187   ⟹   XP_038313115
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2341,574,886 - 41,598,220 (-)NCBI
RefSeq Acc Id: XM_038507907   ⟹   XP_038363835
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12341,915,765 - 41,945,917 (-)NCBI
RefSeq Acc Id: XM_038507908   ⟹   XP_038363836
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12341,915,765 - 41,939,338 (-)NCBI
RefSeq Acc Id: XM_038571148   ⟹   XP_038427076
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02342,234,122 - 42,257,647 (-)NCBI
RefSeq Acc Id: XM_038571149   ⟹   XP_038427077
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02342,234,122 - 42,264,264 (-)NCBI
RefSeq Acc Id: XM_038571150   ⟹   XP_038427078
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02342,234,122 - 42,257,684 (-)NCBI
RefSeq Acc Id: XM_038635341   ⟹   XP_038491269
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02341,990,888 - 42,021,009 (-)NCBI
RefSeq Acc Id: XM_038635342   ⟹   XP_038491270
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02341,990,888 - 42,014,429 (-)NCBI
RefSeq Acc Id: XM_849187   ⟹   XP_854280
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12341,709,662 - 41,739,638 (-)NCBI
Dog10K_Boxer_Tasha2341,574,886 - 41,604,840 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_854280   ⟸   XM_849187
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MH02 (UniProtKB/TrEMBL),   A0A8I3PN12 (UniProtKB/TrEMBL),   A0A8I3P862 (UniProtKB/TrEMBL),   A0A8P0TG56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013962290   ⟸   XM_014106815
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L2Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000038735   ⟸   ENSCAFT00000043736
RefSeq Acc Id: ENSCAFP00000064672   ⟸   ENSCAFT00000087466
RefSeq Acc Id: XP_038363835   ⟸   XM_038507907
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038363836   ⟸   XM_038507908
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038491269   ⟸   XM_038635341
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038491270   ⟸   XM_038635342
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038288538   ⟸   XM_038432610
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MH02 (UniProtKB/TrEMBL),   A0A8I3PN12 (UniProtKB/TrEMBL),   A0A8I3P862 (UniProtKB/TrEMBL),   A0A8P0TG56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038288539   ⟸   XM_038432611
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L2Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038288537   ⟸   XM_038432609
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MH02 (UniProtKB/TrEMBL),   A0A8I3PN12 (UniProtKB/TrEMBL),   A0A8I3P862 (UniProtKB/TrEMBL),   A0A8P0TG56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313115   ⟸   XM_038457187
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MH02 (UniProtKB/TrEMBL),   A0A8I3PN12 (UniProtKB/TrEMBL),   A0A8I3P862 (UniProtKB/TrEMBL),   A0A8P0TG56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038427077   ⟸   XM_038571149
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QI20 (UniProtKB/TrEMBL),   A0A8C0QMF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038427078   ⟸   XM_038571150
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L2Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038427076   ⟸   XM_038571148
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QI20 (UniProtKB/TrEMBL),   A0A8C0QMF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845029655   ⟸   ENSCAFT00845037847
RefSeq Acc Id: ENSCAFP00845029600   ⟸   ENSCAFT00845037775


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031341 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030007267 UniProtKB/TrEMBL
  ENSCAFG00040008290 UniProtKB/TrEMBL
  ENSCAFG00845021401 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000043736.3 UniProtKB/TrEMBL
  ENSCAFT00000087466.2 UniProtKB/TrEMBL
  ENSCAFT00030013326.1 UniProtKB/TrEMBL
  ENSCAFT00040015504.1 UniProtKB/TrEMBL
  ENSCAFT00040015549.1 UniProtKB/TrEMBL
  ENSCAFT00845037775 ENTREZGENE
  ENSCAFT00845037775.1 UniProtKB/TrEMBL
  ENSCAFT00845037847 ENTREZGENE
  ENSCAFT00845037847.1 UniProtKB/TrEMBL
InterPro Scramblase UniProtKB/TrEMBL
  Tubby-like_C UniProtKB/TrEMBL
NCBI Gene LOC611511 ENTREZGENE
PANTHER PHOSPHOLIPID SCRAMBLASE FAMILY MEMBER 5 UniProtKB/TrEMBL
  PTHR23248 UniProtKB/TrEMBL
Pfam Scramblase UniProtKB/TrEMBL
Superfamily-SCOP SSF54518 UniProtKB/TrEMBL
UniProt A0A8C0L2Q3 ENTREZGENE
  A0A8C0MH02 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QI20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QMF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P862 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PN12 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TG56 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:52896 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-27 PLSCR5  phospholipid scramblase family member 5  LOC611511    Symbol and/or name change 5135510 APPROVED