PLSCR5 (phospholipid scramblase family member 5) - Rat Genome Database

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Gene: PLSCR5 (phospholipid scramblase family member 5) Homo sapiens
Analyze
Symbol: PLSCR5
Name: phospholipid scramblase family member 5
RGD ID: 1349492
HGNC Page HGNC:19952
Description: Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: phospholipid scramblase family, member 5
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383146,576,555 - 146,605,346 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3146,576,555 - 146,605,346 (-)EnsemblGRCh38hg38GRCh38
GRCh373146,294,342 - 146,323,133 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363147,786,315 - 147,806,693 (-)NCBINCBI36Build 36hg18NCBI36
Celera3144,720,660 - 144,741,039 (-)NCBICelera
Cytogenetic Map3q24NCBI
HuRef3143,680,464 - 143,700,842 (-)NCBIHuRef
CHM1_13146,266,683 - 146,287,061 (-)NCBICHM1_1
T2T-CHM13v2.03149,331,731 - 149,360,509 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21873635   PMID:22589738   PMID:33961781  


Genomics

Comparative Map Data
PLSCR5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383146,576,555 - 146,605,346 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3146,576,555 - 146,605,346 (-)EnsemblGRCh38hg38GRCh38
GRCh373146,294,342 - 146,323,133 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363147,786,315 - 147,806,693 (-)NCBINCBI36Build 36hg18NCBI36
Celera3144,720,660 - 144,741,039 (-)NCBICelera
Cytogenetic Map3q24NCBI
HuRef3143,680,464 - 143,700,842 (-)NCBIHuRef
CHM1_13146,266,683 - 146,287,061 (-)NCBICHM1_1
T2T-CHM13v2.03149,331,731 - 149,360,509 (-)NCBIT2T-CHM13v2.0
Plscr5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39992,068,569 - 92,094,589 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl992,074,989 - 92,091,825 (+)EnsemblGRCm39 Ensembl
GRCm38992,186,516 - 92,212,536 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl992,192,936 - 92,209,772 (+)EnsemblGRCm38mm10GRCm38
MGSCv37992,087,774 - 92,104,536 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36992,087,774 - 92,104,536 (+)NCBIMGSCv36mm8
Celera991,780,517 - 91,797,373 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map948.33NCBI
Plscr5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88101,597,207 - 101,618,571 (+)NCBIGRCr8
mRatBN7.2892,717,479 - 92,738,843 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl892,722,600 - 92,738,299 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx898,400,883 - 98,416,577 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0896,600,134 - 96,615,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0894,432,845 - 94,448,560 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0899,558,279 - 99,579,791 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl899,568,958 - 99,579,255 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0899,042,074 - 99,063,372 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4897,143,459 - 97,159,158 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera892,241,712 - 92,257,400 (+)NCBICelera
Cytogenetic Map8q31NCBI
Plscr5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547410,855,888 - 10,904,450 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547410,855,958 - 10,903,801 (+)NCBIChiLan1.0ChiLan1.0
PLSCR5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22144,461,879 - 144,490,694 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13144,466,610 - 144,495,425 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03143,593,413 - 143,628,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13151,176,200 - 151,210,799 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3151,176,253 - 151,212,156 (-)Ensemblpanpan1.1panPan2
PLSCR5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12341,709,662 - 41,739,638 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2341,681,017 - 41,733,150 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2341,574,886 - 41,604,840 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02342,327,939 - 42,357,931 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2342,331,540 - 42,357,955 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12341,915,765 - 41,945,917 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02341,990,888 - 42,021,009 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02342,234,122 - 42,264,264 (-)NCBIUU_Cfam_GSD_1.0
Plscr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560281,019,261 - 81,046,315 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365198,694,575 - 8,712,077 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365198,688,210 - 8,712,104 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLSCR5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1386,928,254 - 86,949,019 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11386,920,326 - 86,954,257 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21394,560,866 - 94,587,178 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLSCR5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11544,096,245 - 44,134,975 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1544,106,757 - 44,121,238 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604116,985,249 - 17,012,992 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plscr5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473023,549,667 - 23,565,050 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473023,551,467 - 23,565,050 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PLSCR5
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q23-24(chr3:141751960-148246189)x1 copy number loss See cases [RCV000051575] Chr3:141751960..148246189 [GRCh38]
Chr3:141470802..147963976 [GRCh37]
Chr3:142953492..149446666 [NCBI36]
Chr3:3q23-24		 pathogenic
GRCh38/hg38 3q22.3-29(chr3:137126982-198110178)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051723]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051723]|See cases [RCV000051723] Chr3:137126982..198110178 [GRCh38]
Chr3:136845824..197837049 [GRCh37]
Chr3:138328514..199321446 [NCBI36]
Chr3:3q22.3-29		 pathogenic
NC_000003.12:g.146582660G>A single nucleotide variant Lung cancer [RCV000093029] Chr3:146582660 [GRCh38]
Chr3:146300447 [GRCh37]
Chr3:3q24		 uncertain significance
GRCh38/hg38 3q13.11-29(chr3:103426882-198110178)x3 copy number gain See cases [RCV000134948] Chr3:103426882..198110178 [GRCh38]
Chr3:103145726..197837049 [GRCh37]
Chr3:104628416..199321446 [NCBI36]
Chr3:3q13.11-29		 pathogenic
GRCh38/hg38 3q22.2-25.1(chr3:134257180-149729538)x1 copy number loss See cases [RCV000138135] Chr3:134257180..149729538 [GRCh38]
Chr3:133976022..149447325 [GRCh37]
Chr3:135458712..150930015 [NCBI36]
Chr3:3q22.2-25.1		 pathogenic|likely benign
GRCh37/hg19 3q24-29(chr3:142995020-192997215)x4 copy number gain See cases [RCV000240256] Chr3:142995020..192997215 [GRCh37]
Chr3:3q24-29		 pathogenic
GRCh37/hg19 3q24(chr3:146263729-146405343)x1 copy number loss See cases [RCV000448888] Chr3:146263729..146405343 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.631G>C (p.Glu211Gln) single nucleotide variant not specified [RCV004297683] Chr3:146589799 [GRCh38]
Chr3:146307586 [GRCh37]
Chr3:3q24		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3q24(chr3:146258699-146312941)x3 copy number gain not provided [RCV000742860] Chr3:146258699..146312941 [GRCh37]
Chr3:3q24		 benign
GRCh37/hg19 3q24(chr3:146288645-146323885)x3 copy number gain not provided [RCV000742861] Chr3:146288645..146323885 [GRCh37]
Chr3:3q24		 benign
GRCh37/hg19 3q24(chr3:146289450-146323885)x3 copy number gain not provided [RCV000742862] Chr3:146289450..146323885 [GRCh37]
Chr3:3q24		 benign
GRCh37/hg19 3q24(chr3:146289450-146328944)x3 copy number gain not provided [RCV000742863] Chr3:146289450..146328944 [GRCh37]
Chr3:3q24		 benign
GRCh37/hg19 3q24(chr3:146294395-146323895)x3 copy number gain not provided [RCV000742864] Chr3:146294395..146323895 [GRCh37]
Chr3:3q24		 benign
GRCh37/hg19 3q24(chr3:146294663-146323885)x3 copy number gain not provided [RCV000742865] Chr3:146294663..146323885 [GRCh37]
Chr3:3q24		 benign
GRCh37/hg19 3q24-25.1(chr3:144053029-150272658)x1 copy number loss not provided [RCV001005476] Chr3:144053029..150272658 [GRCh37]
Chr3:3q24-25.1		 likely pathogenic
GRCh37/hg19 3q22.2-24(chr3:135288025-146874012) copy number gain not provided [RCV000767703] Chr3:135288025..146874012 [GRCh37]
Chr3:3q22.2-24		 pathogenic
GRCh37/hg19 3q24(chr3:142909055-147190850)x1 copy number loss not provided [RCV001005475] Chr3:142909055..147190850 [GRCh37]
Chr3:3q24		 uncertain significance
GRCh37/hg19 3q22.3-26.1(chr3:138145289-162275610)x3 copy number gain See cases [RCV001194586] Chr3:138145289..162275610 [GRCh37]
Chr3:3q22.3-26.1		 pathogenic
NC_000003.11:g.(?_145788504)_(147131338_?)del deletion not provided [RCV001351557] Chr3:145788504..147131338 [GRCh37]
Chr3:3q24		 uncertain significance
GRCh37/hg19 3q22.3-26.1(chr3:138173683-162494699) copy number gain Global developmental delay [RCV001352648] Chr3:138173683..162494699 [GRCh37]
Chr3:3q22.3-26.1		 pathogenic
GRCh37/hg19 3q23-25.32(chr3:142729607-157921084)x3 copy number gain Brachycephaly [RCV001801182] Chr3:142729607..157921084 [GRCh37]
Chr3:3q23-25.32		 pathogenic
GRCh37/hg19 3q24-26.1(chr3:143439359-165252122)x1 copy number loss not provided [RCV001795847] Chr3:143439359..165252122 [GRCh37]
Chr3:3q24-26.1		 pathogenic
GRCh37/hg19 3q24-25.33(chr3:145486960-160504834) copy number gain not specified [RCV002053375] Chr3:145486960..160504834 [GRCh37]
Chr3:3q24-25.33		 pathogenic
GRCh37/hg19 3q13.31-26.31(chr3:116620308-172042292)x3 copy number gain not provided [RCV002472621] Chr3:116620308..172042292 [GRCh37]
Chr3:3q13.31-26.31		 pathogenic
NM_001085420.2(PLSCR5):c.733G>A (p.Asp245Asn) single nucleotide variant not specified [RCV004156461] Chr3:146589697 [GRCh38]
Chr3:146307484 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.737T>A (p.Val246Glu) single nucleotide variant not specified [RCV004158087] Chr3:146589693 [GRCh38]
Chr3:146307480 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.271A>C (p.Lys91Gln) single nucleotide variant not specified [RCV004137793] Chr3:146594102 [GRCh38]
Chr3:146311889 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.316A>T (p.Ile106Phe) single nucleotide variant not specified [RCV004133860] Chr3:146594057 [GRCh38]
Chr3:146311844 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.560T>G (p.Leu187Trp) single nucleotide variant not specified [RCV004113887] Chr3:146591775 [GRCh38]
Chr3:146309562 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.551A>G (p.Glu184Gly) single nucleotide variant not specified [RCV004110322] Chr3:146591784 [GRCh38]
Chr3:146309571 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.757A>G (p.Ile253Val) single nucleotide variant not specified [RCV004189113] Chr3:146589673 [GRCh38]
Chr3:146307460 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.16G>T (p.Ala6Ser) single nucleotide variant not specified [RCV004096195] Chr3:146600461 [GRCh38]
Chr3:146318248 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.329G>T (p.Arg110Leu) single nucleotide variant not specified [RCV004330835] Chr3:146594044 [GRCh38]
Chr3:146311831 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.328C>T (p.Arg110Cys) single nucleotide variant not specified [RCV004280668] Chr3:146594045 [GRCh38]
Chr3:146311832 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.583A>C (p.Thr195Pro) single nucleotide variant not specified [RCV004345643] Chr3:146591752 [GRCh38]
Chr3:146309539 [GRCh37]
Chr3:3q24		 uncertain significance
Single allele duplication not provided [RCV003448680] Chr3:140154329..197847235 [GRCh37]
Chr3:3q23-29		 pathogenic
GRCh37/hg19 3q24(chr3:144717495-148147770)x1 copy number loss not specified [RCV003986432] Chr3:144717495..148147770 [GRCh37]
Chr3:3q24		 pathogenic
NM_001085420.2(PLSCR5):c.53C>T (p.Pro18Leu) single nucleotide variant not specified [RCV004506808] Chr3:146600424 [GRCh38]
Chr3:146318211 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.698C>T (p.Ala233Val) single nucleotide variant not specified [RCV004506809] Chr3:146589732 [GRCh38]
Chr3:146307519 [GRCh37]
Chr3:3q24		 uncertain significance
NM_001085420.2(PLSCR5):c.329G>A (p.Arg110His) single nucleotide variant not specified [RCV004506807] Chr3:146594044 [GRCh38]
Chr3:146311831 [GRCh37]
Chr3:3q24		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:359
Count of miRNA genes:182
Interacting mature miRNAs:194
Transcripts:ENST00000443512, ENST00000482567, ENST00000492200
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 2 2
Low 18 3 29 3 3 3 70 2 14 8
Below cutoff 786 137 380 126 156 28 423 171 1832 42 497 202 99 131 244

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000443512   ⟹   ENSP00000390111
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3146,585,837 - 146,605,346 (-)Ensembl
RefSeq Acc Id: ENST00000482567   ⟹   ENSP00000418626
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3146,576,559 - 146,605,239 (-)Ensembl
RefSeq Acc Id: ENST00000492200   ⟹   ENSP00000417184
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3146,576,555 - 146,605,239 (-)Ensembl
RefSeq Acc Id: NM_001085420   ⟹   NP_001078889
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383146,585,837 - 146,605,346 (-)NCBI
GRCh373146,294,342 - 146,324,003 (-)NCBI
Build 363147,786,315 - 147,806,693 (-)NCBI Archive
Celera3144,720,660 - 144,741,039 (-)RGD
HuRef3143,680,464 - 143,700,842 (-)ENTREZGENE
CHM1_13146,266,683 - 146,287,061 (-)NCBI
T2T-CHM13v2.03149,341,002 - 149,360,509 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001321245   ⟹   NP_001308174
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383146,576,555 - 146,605,346 (-)NCBI
CHM1_13146,257,402 - 146,287,061 (-)NCBI
T2T-CHM13v2.03149,331,731 - 149,360,509 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017006373   ⟹   XP_016861862
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383146,589,373 - 146,605,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054346476   ⟹   XP_054202451
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03149,344,541 - 149,360,509 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001078889   ⟸   NM_001085420
- Peptide Label: isoform 1
- UniProtKB: B2RXK5 (UniProtKB/Swiss-Prot),   A0PG75 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001308174   ⟸   NM_001321245
- Peptide Label: isoform 2
- UniProtKB: A0PG75 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016861862   ⟸   XM_017006373
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000417184   ⟸   ENST00000492200
RefSeq Acc Id: ENSP00000418626   ⟸   ENST00000482567
RefSeq Acc Id: ENSP00000390111   ⟸   ENST00000443512
RefSeq Acc Id: XP_054202451   ⟸   XM_054346476
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0PG75-F1-model_v2 AlphaFold A0PG75 1-271 view protein structure

Promoters
RGD ID:6865926
Promoter ID:EPDNEW_H6127
Type:initiation region
Name:PLSCR5_2
Description:phospholipid scramblase family member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H6128  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383146,605,317 - 146,605,377EPDNEW
RGD ID:6865928
Promoter ID:EPDNEW_H6128
Type:initiation region
Name:PLSCR5_1
Description:phospholipid scramblase family member 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H6127  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383146,611,262 - 146,611,322EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:19952 AgrOrtholog
COSMIC PLSCR5 COSMIC
Ensembl Genes ENSG00000231213 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000443512 ENTREZGENE
  ENST00000443512.2 UniProtKB/Swiss-Prot
  ENST00000482567 ENTREZGENE
  ENST00000482567.5 UniProtKB/Swiss-Prot
  ENST00000492200.5 UniProtKB/Swiss-Prot
GTEx ENSG00000231213 GTEx
HGNC ID HGNC:19952 ENTREZGENE
Human Proteome Map PLSCR5 Human Proteome Map
InterPro Scramblase UniProtKB/Swiss-Prot
  Tubby-like_C UniProtKB/Swiss-Prot
KEGG Report hsa:389158 UniProtKB/Swiss-Prot
NCBI Gene 389158 ENTREZGENE
PANTHER PHOSPHOLIPID SCRAMBLASE FAMILY MEMBER 5 UniProtKB/Swiss-Prot
  PTHR23248 UniProtKB/Swiss-Prot
Pfam Scramblase UniProtKB/Swiss-Prot
PharmGKB PA134902268 PharmGKB
Superfamily-SCOP SSF54518 UniProtKB/Swiss-Prot
UniProt A0PG75 ENTREZGENE
  B2RXK5 ENTREZGENE
  L8EC74_HUMAN UniProtKB/TrEMBL
  PLS5_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B2RXK5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 PLSCR5  phospholipid scramblase family member 5    phospholipid scramblase family, member 5  Symbol and/or name change 5135510 APPROVED