Rpl12l2 (ribosomal protein L12 like 2) - Rat Genome Database

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Gene: Rpl12l2 (ribosomal protein L12 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rpl12l2 (Ensembl: RGD1563956)
Name: ribosomal protein L12 like 2 (Ensembl:similar to 60S ribosomal protein L12)
RGD ID: 1563956
Description: INTERACTS WITH bisphenol A
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60S ribosomal protein L12-like; large ribosomal subunit protein uL11-like; LOC303815; RGD1563956; similar to 60S ribosomal protein L12
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81193,673,411 - 93,674,891 (+)NCBIGRCr8
mRatBN7.21180,169,205 - 80,169,831 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,169,205 - 80,169,807 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01183,855,637 - 83,856,331 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01186,927,632 - 86,928,234 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,399,041 - 82,399,514 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1179,008,877 - 79,009,575 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IBA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rpl12l2
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:42
Interacting mature miRNAs:42
Transcripts:ENSRNOT00000030686
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000030686   ⟹   ENSRNOP00000030437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,169,205 - 80,169,807 (+)Ensembl
Rnor_6.0 Ensembl1183,855,753 - 83,856,316 (+)Ensembl
RefSeq Acc Id: XM_039088715   ⟹   XP_038944643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,673,411 - 93,674,891 (+)NCBI
mRatBN7.21180,169,205 - 80,169,831 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038944643 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030437
  ENSRNOP00000030437.6
Reference Protein Sequences
RefSeq Acc Id: XP_038944643   ⟸   XM_039088715
- UniProtKB: D4A8N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000030437   ⟸   ENSRNOT00000030686
Protein Domains
Large ribosomal subunit protein uL11 C-terminal   Large ribosomal subunit protein uL11 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A8N3-F1-model_v2 AlphaFold D4A8N3 1-187 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563956 AgrOrtholog
BioCyc Gene G2FUF-20758 BioCyc
Ensembl Genes ENSRNOG00000025014 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030686.6 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.250 UniProtKB/TrEMBL
  3.30.1550.10 UniProtKB/TrEMBL
InterPro Ribosomal_L11/L12 UniProtKB/TrEMBL
  Ribosomal_L11/L12_N_sf UniProtKB/TrEMBL
  Ribosomal_L11_C UniProtKB/TrEMBL
  Ribosomal_L11_C_sf UniProtKB/TrEMBL
  Ribosomal_L11_CS UniProtKB/TrEMBL
  Ribosomal_L11_N UniProtKB/TrEMBL
NCBI Gene 303815 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L12 UniProtKB/TrEMBL
  PTHR11661 UniProtKB/TrEMBL
Pfam Ribosomal_L11 UniProtKB/TrEMBL
  Ribosomal_L11_N UniProtKB/TrEMBL
PhenoGen Rpl12l2 PhenoGen
PROSITE RIBOSOMAL_L11 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025014 RatGTEx
SMART RL11 UniProtKB/TrEMBL
Superfamily-SCOP SSF46906 UniProtKB/TrEMBL
  SSF54747 UniProtKB/TrEMBL
UniProt D4A8N3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rpl12l2  ribosomal protein L12 like 2  RGD1563956  similar to 60S ribosomal protein L12  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1563956  similar to 60S ribosomal protein L12   RGD1563956_predicted  similar to 60S ribosomal protein L12 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563956_predicted  similar to 60S ribosomal protein L12 (predicted)  LOC303815  similar to 60S ribosomal protein L12  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC303815  similar to 60S ribosomal protein L12      Symbol and Name status set to provisional 70820 PROVISIONAL