Ankar (ankyrin and armadillo repeat containing) - Rat Genome Database

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Gene: Ankar (ankyrin and armadillo repeat containing) Rattus norvegicus
Analyze
Symbol: Ankar
Name: ankyrin and armadillo repeat containing
RGD ID: 1561071
Description: Orthologous to human ANKAR (ankyrin and armadillo repeat containing); INTERACTS WITH bisphenol A; copper atom; copper(0).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC501138; RGD1561071; similar to RIKEN cDNA 4932422E22 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8955,633,681 - 55,709,721 (+)NCBIGRCr8
mRatBN7.2948,141,534 - 48,215,400 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl948,141,391 - 48,215,616 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0953,011,561 - 53,086,178 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl953,013,413 - 53,084,010 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0952,677,310 - 52,748,471 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4945,083,658 - 45,164,758 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera945,808,647 - 45,883,471 (+)NCBICelera
Cytogenetic Map9q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Comparative Map Data
Ankar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8955,633,681 - 55,709,721 (+)NCBIGRCr8
mRatBN7.2948,141,534 - 48,215,400 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl948,141,391 - 48,215,616 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0953,011,561 - 53,086,178 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl953,013,413 - 53,084,010 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0952,677,310 - 52,748,471 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4945,083,658 - 45,164,758 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera945,808,647 - 45,883,471 (+)NCBICelera
Cytogenetic Map9q22NCBI
ANKAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382189,674,670 - 189,763,059 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2189,674,290 - 189,761,193 (+)EnsemblGRCh38hg38GRCh38
GRCh372190,539,396 - 190,611,376 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362190,249,675 - 190,319,615 (+)NCBINCBI36Build 36hg18NCBI36
Celera2184,135,616 - 184,206,285 (+)NCBICelera
Cytogenetic Map2q32.2NCBI
HuRef2182,400,195 - 182,471,007 (+)NCBIHuRef
CHM1_12190,546,561 - 190,617,250 (+)NCBICHM1_1
T2T-CHM13v2.02190,163,912 - 190,252,329 (+)NCBIT2T-CHM13v2.0
Ankar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39172,682,139 - 72,739,743 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl172,682,139 - 72,739,738 (-)EnsemblGRCm39 Ensembl
GRCm38172,642,980 - 72,700,584 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl172,642,980 - 72,700,579 (-)EnsemblGRCm38mm10GRCm38
MGSCv37172,689,554 - 72,747,138 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36172,576,187 - 72,633,771 (-)NCBIMGSCv36mm8
Celera173,211,530 - 73,268,878 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map136.8NCBI
Ankar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554039,133,009 - 9,173,451 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554039,132,988 - 9,174,959 (-)NCBIChiLan1.0ChiLan1.0
ANKAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21392,363,509 - 92,438,800 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B92,378,373 - 92,453,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B76,977,471 - 77,052,729 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B194,900,868 - 194,972,543 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B194,902,795 - 194,972,504 (+)Ensemblpanpan1.1panPan2
ANKAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137437,744 - 489,008 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl37438,259 - 489,008 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha371,410,346 - 1,462,026 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.037328,868 - 381,837 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl37330,238 - 381,837 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.137341,173 - 392,842 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.037309,679 - 361,324 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.037337,623 - 389,276 (+)NCBIUU_Cfam_GSD_1.0
Ankar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303148,537,917 - 148,611,637 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365068,226,498 - 8,299,419 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365068,226,068 - 8,299,455 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1594,274,741 - 94,336,791 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11594,276,904 - 94,336,484 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215104,724,084 - 104,763,278 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANKAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11075,193,158 - 75,283,782 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1075,193,460 - 75,268,326 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040124,211,907 - 124,285,828 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Ankar
638 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:18
Count of miRNA genes:17
Interacting mature miRNAs:18
Transcripts:ENSRNOT00000005313
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
6903937Bp356Blood pressure QTL 3560.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94790220852283252Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat

Markers in Region
RH133567  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2948,138,753 - 48,138,953 (+)MAPPERmRatBN7.2
mRatBN7.21581,737,740 - 81,737,939 (+)MAPPERmRatBN7.2
Rnor_6.01589,116,357 - 89,116,555NCBIRnor6.0
Rnor_6.0953,008,735 - 53,008,934NCBIRnor6.0
Rnor_5.01592,608,221 - 92,608,419UniSTSRnor5.0
Rnor_5.0952,674,551 - 52,674,750UniSTSRnor5.0
RGSC_v3.41589,027,338 - 89,027,536UniSTSRGSC3.4
RGSC_v3.4945,088,737 - 45,088,936UniSTSRGSC3.4
Celera945,806,063 - 45,806,262UniSTS
Celera1580,862,882 - 80,863,080UniSTS
Cytogenetic Map9q22UniSTS
Cytogenetic Map15q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 47 91 51 50 19 25 19 6 148 94 71 18 50 31

Sequence


Ensembl Acc Id: ENSRNOT00000005313   ⟹   ENSRNOP00000005314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl948,141,391 - 48,215,379 (+)Ensembl
Rnor_6.0 Ensembl953,013,413 - 53,084,010 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115410   ⟹   ENSRNOP00000085648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl948,141,391 - 48,215,616 (+)Ensembl
RefSeq Acc Id: XM_039084557   ⟹   XP_038940485
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,633,836 - 55,709,721 (+)NCBI
mRatBN7.2948,141,535 - 48,215,400 (+)NCBI
RefSeq Acc Id: XM_039084558   ⟹   XP_038940486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,633,969 - 55,709,721 (+)NCBI
mRatBN7.2948,141,535 - 48,215,400 (+)NCBI
RefSeq Acc Id: XM_039084559   ⟹   XP_038940487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,633,681 - 55,709,721 (+)NCBI
mRatBN7.2948,141,535 - 48,215,400 (+)NCBI
RefSeq Acc Id: XM_063268120   ⟹   XP_063124190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,633,836 - 55,701,777 (+)NCBI
RefSeq Acc Id: XR_005489134
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,633,836 - 55,701,774 (+)NCBI
mRatBN7.2948,141,536 - 48,209,771 (+)NCBI
RefSeq Acc Id: XR_005489135
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,633,836 - 55,705,436 (+)NCBI
mRatBN7.2948,141,535 - 48,213,448 (+)NCBI
Ensembl Acc Id: ENSRNOP00000005314   ⟸   ENSRNOT00000005313
RefSeq Acc Id: XP_038940486   ⟸   XM_039084558
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038940485   ⟸   XM_039084557
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038940487   ⟸   XM_039084559
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000085648   ⟸   ENSRNOT00000115410
RefSeq Acc Id: XP_063124190   ⟸   XM_063268120
- Peptide Label: isoform X2
- UniProtKB: A6INU2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LUI7-F1-model_v2 AlphaFold F1LUI7 1-1440 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561071 AgrOrtholog
BioCyc Gene G2FUF-27630 BioCyc
Ensembl Genes ENSRNOG00000003991 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005313.8 UniProtKB/TrEMBL
  ENSRNOT00000115410.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
InterPro ANKAR UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
NCBI Gene 501138 ENTREZGENE
PANTHER ANKYRIN AND ARMADILLO REPEAT-CONTAINING PROTEIN UniProtKB/TrEMBL
  PTHR46464 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
  Arm UniProtKB/TrEMBL
PhenoGen Ankar PhenoGen
PROSITE ANK_REPEAT UniProtKB/TrEMBL
  ARM_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003991 RatGTEx
SMART ANK UniProtKB/TrEMBL
  ARM UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
UniProt A0A8I6A4B4_RAT UniProtKB/TrEMBL
  A6INU2 ENTREZGENE, UniProtKB/TrEMBL
  F1LUI7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-28 Ankar  ankyrin and armadillo repeat containing  RGD1561071_predicted  similar to RIKEN cDNA 4932422E22 gene (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561071_predicted  similar to RIKEN cDNA 4932422E22 gene (predicted)  LOC501138  similar to RIKEN cDNA 4932422E22 gene  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501138  similar to RIKEN cDNA 4932422E22 gene      Symbol and Name status set to provisional 70820 PROVISIONAL