Lrrc14 (leucine rich repeat containing 14) - Rat Genome Database

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Gene: Lrrc14 (leucine rich repeat containing 14) Rattus norvegicus
Analyze
Symbol: Lrrc14
Name: leucine rich repeat containing 14
RGD ID: 1560202
Description: Predicted to enable kinase binding activity. Predicted to be involved in negative regulation of toll-like receptor signaling pathway. Predicted to be active in cytoplasm. Orthologous to human LRRC14 (leucine rich repeat containing 14); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leucine-rich repeat-containing protein 14; MGC108882; similar to Leucine-rich repeat-containing 14
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,311,384 - 110,317,757 (+)NCBIGRCr8
mRatBN7.27108,430,755 - 108,437,118 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,430,792 - 108,437,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,172,674 - 110,179,050 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,396,248 - 112,402,624 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,357,001 - 112,363,361 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,773,219 - 117,779,555 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,773,230 - 117,779,505 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,761,186 - 117,767,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,760,919 - 114,766,477 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7104,781,396 - 104,786,954 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)

Molecular Function
kinase binding  (IBA,IEA,ISO)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:27426725  


Genomics

Comparative Map Data
Lrrc14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,311,384 - 110,317,757 (+)NCBIGRCr8
mRatBN7.27108,430,755 - 108,437,118 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,430,792 - 108,437,111 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,172,674 - 110,179,050 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,396,248 - 112,402,624 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,357,001 - 112,363,361 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,773,219 - 117,779,555 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,773,230 - 117,779,505 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,761,186 - 117,767,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,760,919 - 114,766,477 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7104,781,396 - 104,786,954 (+)NCBICelera
Cytogenetic Map7q34NCBI
LRRC14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,517,992 - 144,525,178 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,517,992 - 144,525,172 (+)EnsemblGRCh38hg38GRCh38
GRCh378145,743,376 - 145,750,556 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,714,199 - 145,721,365 (+)NCBINCBI36Build 36hg18NCBI36
Build 348145,714,198 - 145,721,365NCBI
Celera8141,919,071 - 141,926,237 (+)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,856,834 - 140,864,047 (+)NCBIHuRef
CHM1_18145,781,538 - 145,788,752 (+)NCBICHM1_1
T2T-CHM13v2.08145,688,176 - 145,695,358 (+)NCBIT2T-CHM13v2.0
Lrrc14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,594,820 - 76,599,297 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,594,823 - 76,601,899 (+)EnsemblGRCm39 Ensembl
GRCm381576,710,615 - 76,715,097 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,710,623 - 76,717,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv371576,541,170 - 76,545,521 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,537,995 - 76,542,346 (+)NCBIMGSCv36mm8
Celera1578,204,350 - 78,208,701 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.28NCBI
Lrrc14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,142,636 - 3,146,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554543,142,621 - 3,146,470 (+)NCBIChiLan1.0ChiLan1.0
LRRC14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27162,011,911 - 162,014,202 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,539,464 - 137,543,633 (+)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl8144,274,769 - 144,278,442 (+)Ensemblpanpan1.1panPan2
LRRC14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,937,437 - 37,941,202 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,937,111 - 37,941,703 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,897,740 - 37,901,510 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,410,725 - 38,414,495 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,408,727 - 38,414,495 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11338,102,671 - 38,106,439 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01338,211,083 - 38,214,853 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,687,562 - 38,691,332 (+)NCBIUU_Cfam_GSD_1.0
Lrrc14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303325,324 - 328,813 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364707,751,426 - 7,755,272 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4279,764 - 287,062 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14279,756 - 287,085 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24371,155 - 378,053 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,732,276 - 138,736,348 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,734,046 - 138,735,804 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,115,429 - 1,122,666 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrc14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473512,337,564 - 12,345,260 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lrrc14
31 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:399
Count of miRNA genes:217
Interacting mature miRNAs:256
Transcripts:ENSRNOT00000021673
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
AW531492  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,437,385 - 108,437,536 (+)MAPPERmRatBN7.2
Rnor_6.07117,779,823 - 117,779,973NCBIRnor6.0
Rnor_5.07117,767,802 - 117,767,952UniSTSRnor5.0
RGSC_v3.47114,766,794 - 114,766,944UniSTSRGSC3.4
Celera7104,787,271 - 104,787,421UniSTS
RH 3.4 Map7792.9UniSTS
Cytogenetic Map7q34UniSTS
RH140300  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,436,677 - 108,436,860 (+)MAPPERmRatBN7.2
Rnor_6.07117,779,115 - 117,779,297NCBIRnor6.0
Rnor_5.07117,767,094 - 117,767,276UniSTSRnor5.0
RGSC_v3.47114,766,086 - 114,766,268UniSTSRGSC3.4
Celera7104,786,563 - 104,786,745UniSTS
RH 3.4 Map7795.5UniSTS
Cytogenetic Map7q34UniSTS
AW530743  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,437,071 - 108,437,265 (+)MAPPERmRatBN7.2
Rnor_6.07117,779,509 - 117,779,702NCBIRnor6.0
Rnor_5.07117,767,488 - 117,767,681UniSTSRnor5.0
RGSC_v3.47114,766,480 - 114,766,673UniSTSRGSC3.4
Celera7104,786,957 - 104,787,150UniSTS
RH 3.4 Map7793.5UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 18 78 91 25 60 25 227 89 135 51
Low 3 63 136 122 9 122 36 45 23 26 10 24
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001024354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000021673   ⟹   ENSRNOP00000021673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,434,912 - 108,437,111 (+)Ensembl
Rnor_6.0 Ensembl7117,773,948 - 117,779,505 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077562   ⟹   ENSRNOP00000069176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,430,806 - 108,437,100 (+)Ensembl
Rnor_6.0 Ensembl7117,773,230 - 117,779,318 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097197   ⟹   ENSRNOP00000083734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,430,792 - 108,437,100 (+)Ensembl
RefSeq Acc Id: NM_001024354   ⟹   NP_001019525
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,312,150 - 110,317,708 (+)NCBI
mRatBN7.27108,431,511 - 108,437,069 (+)NCBI
Rnor_6.07117,773,948 - 117,779,506 (+)NCBI
Rnor_5.07117,761,186 - 117,767,499 (+)NCBI
RGSC_v3.47114,760,919 - 114,766,477 (+)RGD
Celera7104,781,396 - 104,786,954 (+)RGD
Sequence:
RefSeq Acc Id: NM_001401224   ⟹   NP_001388153
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,394 - 110,317,757 (+)NCBI
mRatBN7.27108,430,755 - 108,437,118 (+)NCBI
RefSeq Acc Id: XM_006241862   ⟹   XP_006241924
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,450 - 110,317,757 (+)NCBI
mRatBN7.27108,430,802 - 108,437,118 (+)NCBI
Rnor_6.07117,773,530 - 117,779,555 (+)NCBI
Rnor_5.07117,761,186 - 117,767,499 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079758   ⟹   XP_038935686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,693 - 110,317,757 (+)NCBI
mRatBN7.27108,430,802 - 108,437,118 (+)NCBI
RefSeq Acc Id: XM_039079759   ⟹   XP_038935687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,450 - 110,317,757 (+)NCBI
mRatBN7.27108,430,779 - 108,437,118 (+)NCBI
RefSeq Acc Id: XM_063264128   ⟹   XP_063120198
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,451 - 110,317,757 (+)NCBI
RefSeq Acc Id: XM_063264130   ⟹   XP_063120200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,451 - 110,317,757 (+)NCBI
RefSeq Acc Id: XM_063264131   ⟹   XP_063120201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,384 - 110,317,757 (+)NCBI
RefSeq Acc Id: XM_063264132   ⟹   XP_063120202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,451 - 110,317,757 (+)NCBI
RefSeq Acc Id: XM_063264133   ⟹   XP_063120203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,311,693 - 110,317,757 (+)NCBI
RefSeq Acc Id: NP_001019525   ⟸   NM_001024354
- Peptide Label: isoform 2
- UniProtKB: Q569B5 (UniProtKB/Swiss-Prot),   A0A8L2UJL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241924   ⟸   XM_006241862
- Peptide Label: isoform X3
- UniProtKB: Q569B5 (UniProtKB/Swiss-Prot),   A0A8L2UJL0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021673   ⟸   ENSRNOT00000021673
Ensembl Acc Id: ENSRNOP00000069176   ⟸   ENSRNOT00000077562
RefSeq Acc Id: XP_038935687   ⟸   XM_039079759
- Peptide Label: isoform X1
- UniProtKB: A0A8L2UJL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935686   ⟸   XM_039079758
- Peptide Label: isoform X1
- UniProtKB: A0A8L2UJL0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083734   ⟸   ENSRNOT00000097197
RefSeq Acc Id: NP_001388153   ⟸   NM_001401224
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JUP6 (UniProtKB/TrEMBL),   A0A8L2UJL0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120201   ⟸   XM_063264131
- Peptide Label: isoform X2
- UniProtKB: A0A8L2UJL0 (UniProtKB/TrEMBL),   A0A8I5ZZT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120200   ⟸   XM_063264130
- Peptide Label: isoform X2
- UniProtKB: A0A8L2UJL0 (UniProtKB/TrEMBL),   A0A8I5ZZT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120198   ⟸   XM_063264128
- Peptide Label: isoform X2
- UniProtKB: A0A8L2UJL0 (UniProtKB/TrEMBL),   A0A8I5ZZT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120202   ⟸   XM_063264132
- Peptide Label: isoform X2
- UniProtKB: A0A8L2UJL0 (UniProtKB/TrEMBL),   A0A8I5ZZT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120203   ⟸   XM_063264133
- Peptide Label: isoform X2
- UniProtKB: A0A8L2UJL0 (UniProtKB/TrEMBL),   A0A8I5ZZT2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q569B5-F1-model_v2 AlphaFold Q569B5 1-493 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695445
Promoter ID:EPDNEW_R5962
Type:multiple initiation site
Name:Lrrc14_1
Description:leucine rich repeat containing 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07117,773,257 - 117,773,317EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560202 AgrOrtholog
BioCyc Gene G2FUF-32906 BioCyc
Ensembl Genes ENSRNOG00000016128 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00065030366 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021673.5 UniProtKB/TrEMBL
  ENSRNOT00000077562.2 UniProtKB/TrEMBL
  ENSRNOT00000097197.1 UniProtKB/TrEMBL
  ENSRNOT00065052378 UniProtKB/Swiss-Prot
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7376401 IMAGE-MGC_LOAD
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRAME_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:108882 IMAGE-MGC_LOAD
NCBI Gene 500900 ENTREZGENE
PANTHER PTHR14224:SF9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LRR_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lrrc14 PhenoGen
RatGTEx ENSRNOG00000016128 RatGTEx
  ENSRNOG00065030366 RatGTEx
Superfamily-SCOP RNI-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUP6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZZT2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UJL0 ENTREZGENE, UniProtKB/TrEMBL
  LRC14_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Lrrc14  leucine rich repeat containing 14  MGC108882  similar to Leucine-rich repeat-containing 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 MGC108882  similar to Leucine-rich repeat-containing 14      Symbol and Name status set to provisional 70820 PROVISIONAL