Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mical3 | Rat | (+)-catechin | multiple interactions | ISO | MICAL3 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of MICAL3 mRNA | CTD | PMID:24763279 | Mical3 | Rat | (-)-demecolcine | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of MICAL3 mRNA | CTD | PMID:23649840 | Mical3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Mical3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of MICAL3 mRNA | CTD | PMID:36331819 | Mical3 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Mical3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of MICAL3 mRNA | CTD | PMID:22206623 | Mical3 | Rat | 17beta-estradiol | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Estradiol results in increased expression of MICAL3 mRNA | CTD | PMID:31614463 | Mical3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mical3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MICAL3 mRNA | CTD | PMID:21570461 | Mical3 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Mical3 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of MICAL3 mRNA | CTD | PMID:26251327 | Mical3 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Mical3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of MICAL3 gene | CTD | PMID:31683443 | Mical3 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of MICAL3 mRNA | CTD | PMID:24780913 | Mical3 | Rat | aflatoxin B1 | increases methylation | ISO | MICAL3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of MICAL3 gene and Aflatoxin B1 results in increased methylation of MICAL3 intron | CTD | PMID:27153756 and PMID:30157460 | Mical3 | Rat | all-trans-retinoic acid | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of MICAL3 mRNA | CTD | PMID:33167477 | Mical3 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of MICAL3 gene | CTD | PMID:35440735 | Mical3 | Rat | benzo[a]pyrene | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MICAL3 mRNA | CTD | PMID:20106945 and PMID:21632981 | Mical3 | Rat | benzo[a]pyrene | affects methylation | ISO | MICAL3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MICAL3 5' UTR more ... | CTD | PMID:27901495 and PMID:30157460 | Mical3 | Rat | benzo[a]pyrene | increases expression | ISO | Mical3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of MICAL3 mRNA | CTD | PMID:22228805 | Mical3 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MICAL3 mRNA | CTD | PMID:25181051 and PMID:32145629 | Mical3 | Rat | bisphenol A | multiple interactions | ISO | MICAL3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MICAL3 gene | CTD | PMID:31601247 | Mical3 | Rat | bisphenol A | decreases methylation | ISO | MICAL3 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of MICAL3 gene | CTD | PMID:31601247 | Mical3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MICAL3 mRNA | CTD | PMID:30816183 | Mical3 | Rat | bisphenol A | increases methylation | ISO | Mical3 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of MICAL3 promoter | CTD | PMID:27312807 | Mical3 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of MICAL3 gene | CTD | PMID:28505145 | Mical3 | Rat | buta-1,3-diene | decreases expression | ISO | Mical3 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of MICAL3 mRNA | CTD | PMID:29038090 | Mical3 | Rat | butanal | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of MICAL3 mRNA | CTD | PMID:26079696 | Mical3 | Rat | calcitriol | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of MICAL3 mRNA | CTD | PMID:26485663 | Mical3 | Rat | cannabidiol | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Cannabidiol results in decreased expression of MICAL3 mRNA | CTD | PMID:27714895 | Mical3 | Rat | carbon nanotube | decreases expression | ISO | Mical3 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of MICAL3 mRNA | CTD | PMID:25554681 | Mical3 | Rat | chlorpyrifos | decreases expression | ISO | Mical3 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of MICAL3 mRNA | CTD | PMID:37019170 | Mical3 | Rat | clobetasol | decreases expression | ISO | Mical3 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of MICAL3 mRNA | CTD | PMID:27462272 | Mical3 | Rat | coumarin | increases phosphorylation | ISO | MICAL3 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of MICAL3 protein | CTD | PMID:35688186 | Mical3 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of MICAL3 mRNA | CTD | PMID:26577399 | Mical3 | Rat | dicrotophos | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of MICAL3 mRNA | CTD | PMID:28302478 | Mical3 | Rat | doxorubicin | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MICAL3 mRNA | CTD | PMID:29803840 | Mical3 | Rat | ethanol | affects splicing | ISO | Mical3 (Mus musculus) | 6480464 | Ethanol affects the splicing of MICAL3 mRNA | CTD | PMID:30319688 | Mical3 | Rat | ethanol | affects expression | ISO | Mical3 (Mus musculus) | 6480464 | Ethanol affects the expression of MICAL3 mRNA | CTD | PMID:30319688 | Mical3 | Rat | fenthion | decreases expression | ISO | Mical3 (Mus musculus) | 6480464 | Fenthion results in decreased expression of MICAL3 mRNA | CTD | PMID:34813904 | Mical3 | Rat | FR900359 | affects phosphorylation | ISO | MICAL3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of MICAL3 protein | CTD | PMID:37730182 | Mical3 | Rat | fulvestrant | multiple interactions | ISO | MICAL3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MICAL3 gene | CTD | PMID:31601247 | Mical3 | Rat | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of MICAL3 mRNA | CTD | PMID:24915197 | Mical3 | Rat | hydralazine | multiple interactions | ISO | MICAL3 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of MICAL3 mRNA | CTD | PMID:17183730 | Mical3 | Rat | inulin | multiple interactions | ISO | Mical3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of MICAL3 mRNA | CTD | PMID:36331819 | Mical3 | Rat | ivermectin | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of MICAL3 protein | CTD | PMID:32959892 | Mical3 | Rat | lead(0) | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Lead results in decreased expression of MICAL3 mRNA | CTD | PMID:19921347 | Mical3 | Rat | lead(0) | affects expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Lead affects the expression of MICAL3 mRNA | CTD | PMID:28903495 | Mical3 | Rat | maneb | multiple interactions | ISO | Mical3 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of MICAL3 mRNA | CTD | PMID:36117858 | Mical3 | Rat | methamphetamine | increases expression | ISO | Mical3 (Mus musculus) | 6480464 | Methamphetamine results in increased expression of MICAL3 mRNA | CTD | PMID:26307267 | Mical3 | Rat | methamphetamine | increases methylation | ISO | Mical3 (Mus musculus) | 6480464 | Methamphetamine results in increased methylation of MICAL3 promoter | CTD | PMID:26307267 | Mical3 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of MICAL3 mRNA | CTD | PMID:30467583 | Mical3 | Rat | methotrexate | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of MICAL3 mRNA | CTD | PMID:24449571 | Mical3 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of MICAL3 gene | CTD | PMID:35440735 | Mical3 | Rat | methyl methanesulfonate | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of MICAL3 mRNA | CTD | PMID:23649840 | Mical3 | Rat | monosodium L-glutamate | increases expression | ISO | Mical3 (Mus musculus) | 6480464 | Sodium Glutamate results in increased expression of MICAL3 mRNA | CTD | PMID:20111022 | Mical3 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of MICAL3 gene | CTD | PMID:33148267 | Mical3 | Rat | p-chloromercuribenzoic acid | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of MICAL3 mRNA | CTD | PMID:27188386 | Mical3 | Rat | paracetamol | affects expression | ISO | Mical3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MICAL3 mRNA | CTD | PMID:17562736 | Mical3 | Rat | paracetamol | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MICAL3 mRNA | CTD | PMID:26690555 | Mical3 | Rat | paracetamol | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MICAL3 mRNA | CTD | PMID:22230336 | Mical3 | Rat | paraquat | multiple interactions | ISO | Mical3 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of MICAL3 mRNA | CTD | PMID:36117858 | Mical3 | Rat | pentanal | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | pentanal results in decreased expression of MICAL3 mRNA | CTD | PMID:26079696 | Mical3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Mical3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of MICAL3 mRNA more ... | CTD | PMID:36331819 | Mical3 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of MICAL3 gene | CTD | PMID:33148267 | Mical3 | Rat | quercetin | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Quercetin results in increased expression of MICAL3 mRNA | CTD | PMID:21632981 | Mical3 | Rat | sodium arsenite | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MICAL3 mRNA | CTD | PMID:34032870 | Mical3 | Rat | tetrachloromethane | increases expression | ISO | Mical3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of MICAL3 mRNA | CTD | PMID:17484886 | Mical3 | Rat | triclosan | decreases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of MICAL3 mRNA | CTD | PMID:30510588 | Mical3 | Rat | triphenyl phosphate | affects expression | ISO | MICAL3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of MICAL3 mRNA | CTD | PMID:37042841 | Mical3 | Rat | Triptolide | increases expression | ISO | Mical3 (Mus musculus) | 6480464 | triptolide results in increased expression of MICAL3 mRNA | CTD | PMID:32835833 | Mical3 | Rat | triptonide | affects expression | ISO | Mical3 (Mus musculus) | 6480464 | triptonide affects the expression of MICAL3 mRNA | CTD | PMID:33045310 | Mical3 | Rat | triptonide | decreases expression | ISO | Mical3 (Mus musculus) | 6480464 | triptonide results in decreased expression of MICAL3 mRNA | CTD | PMID:33045310 | Mical3 | Rat | urethane | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Urethane results in increased expression of MICAL3 mRNA | CTD | PMID:28818685 | Mical3 | Rat | valproic acid | affects expression | ISO | Mical3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of MICAL3 mRNA | CTD | PMID:17292431 | Mical3 | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of MICAL3 mRNA | CTD | PMID:29427782 | Mical3 | Rat | valproic acid | multiple interactions | ISO | MICAL3 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of MICAL3 mRNA | CTD | PMID:17183730 | Mical3 | Rat | valproic acid | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MICAL3 mRNA | CTD | PMID:23179753 | Mical3 | Rat | vincristine | increases expression | ISO | MICAL3 (Homo sapiens) | 6480464 | Vincristine results in increased expression of MICAL3 mRNA | CTD | PMID:23649840 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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