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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359504
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects splicingEXP 6480464CTDValproic Acid affects the splicing of MICAL3 mRNA

PMID:29427782
affects expressionISORGD:15502816480464CTDValproic Acid affects the expression of MICAL3 mRNA

PMID:17292431
increases expressionISORGD:16030166480464CTDValproic Acid results in increased expression of MICAL3 mRNA

PMID:23179753
multiple interactionsISORGD:16030166480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of MICAL3 mRNA

PMID:17183730
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.