Vasp (vasodilator-stimulated phosphoprotein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Vasp (vasodilator-stimulated phosphoprotein) Rattus norvegicus
Analyze
Symbol: Vasp
Name: vasodilator-stimulated phosphoprotein
RGD ID: 1311542
Description: Predicted to enable profilin binding activity. Predicted to be involved in actin polymerization or depolymerization; nervous system development; and positive regulation of actin filament polymerization. Predicted to act upstream of or within actin cytoskeleton organization. Is active in glutamatergic synapse and postsynapse. Orthologous to human VASP (vasodilator stimulated phosphoprotein); PARTICIPATES IN E-cadherin signaling pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC361517
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,038,026 - 88,053,783 (-)NCBIGRCr8
mRatBN7.2178,910,009 - 78,925,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,910,011 - 78,925,061 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,299,066 - 84,313,957 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,856,629 - 92,871,541 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,054,149 - 86,069,040 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,170,608 - 80,185,882 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,170,619 - 80,185,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,437,091 - 81,452,900 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,621,494 - 78,636,762 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,699,598 - 78,715,028 (-)NCBI
Celera173,372,332 - 73,387,227 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-(4-chlorophenylthio)-cGMP  (EXP,ISO)
acetaldehyde  (ISO)
acetamide  (EXP)
ADP  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benomyl  (EXP)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bortezomib  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium atom  (EXP)
clopidogrel  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
DDE  (ISO)
dexamethasone  (EXP,ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fipronil  (EXP)
flusilazole  (ISO)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
hemin  (EXP)
indometacin  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
nebivolol  (EXP)
nickel atom  (ISO)
nitroglycerin  (EXP,ISO)
oxycodone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
pentaerythritol tetranitrate  (EXP)
perfluorohexanesulfonic acid  (ISO)
phenobarbital  (EXP)
progesterone  (ISO)
propiconazole  (EXP)
prostaglandin E1  (ISO)
prostaglandin E2  (ISO)
resveratrol  (EXP,ISO)
S-nitroso-N-acetyl-D-penicillamine  (EXP)
SB 203580  (ISO)
SB 431542  (ISO)
silibinin  (ISO)
Silidianin  (ISO)
silychristin  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
staurosporine  (ISO)
sucrose  (EXP)
sulfadimethoxine  (EXP)
sulindac sulfone  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamibarotene  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytoskeleton  (IEA)
cytosol  (IEA,ISO)
filopodium  (ISO)
focal adhesion  (IBA,ISO)
glutamatergic synapse  (IDA,IMP)
lamellipodium  (ISO)
plasma membrane  (IBA,ISO)
postsynapse  (IDA,IMP)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion. Chazeau A, etal., EMBO J. 2014 Dec 1;33(23):2745-64. doi: 10.15252/embj.201488837. Epub 2014 Oct 7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15148305   PMID:15294161   PMID:15371503   PMID:17914456   PMID:18571642   PMID:19056867   PMID:19442672   PMID:20458337   PMID:20599605   PMID:21423176   PMID:23153535  
PMID:24580804   PMID:24779009   PMID:24894047   PMID:25468996   PMID:26221026   PMID:26264698   PMID:27957528   PMID:28376489   PMID:31505169  


Genomics

Comparative Map Data
Vasp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,038,026 - 88,053,783 (-)NCBIGRCr8
mRatBN7.2178,910,009 - 78,925,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,910,011 - 78,925,061 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,299,066 - 84,313,957 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,856,629 - 92,871,541 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,054,149 - 86,069,040 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,170,608 - 80,185,882 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,170,619 - 80,185,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,437,091 - 81,452,900 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,621,494 - 78,636,762 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,699,598 - 78,715,028 (-)NCBI
Celera173,372,332 - 73,387,227 (-)NCBICelera
Cytogenetic Map1q21NCBI
VASP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,507,479 - 45,526,983 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,506,579 - 45,526,989 (+)EnsemblGRCh38hg38GRCh38
GRCh371946,010,737 - 46,030,241 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,702,528 - 50,722,081 (+)NCBINCBI36Build 36hg18NCBI36
Build 341950,702,527 - 50,722,078NCBI
Celera1942,816,794 - 42,836,352 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,440,143 - 42,459,463 (+)NCBIHuRef
CHM1_11946,013,932 - 46,033,484 (+)NCBICHM1_1
T2T-CHM13v2.01948,334,741 - 48,354,257 (+)NCBIT2T-CHM13v2.0
Vasp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,990,854 - 19,005,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,990,854 - 19,005,742 (-)EnsemblGRCm39 Ensembl
GRCm38719,256,929 - 19,271,854 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,256,929 - 19,271,817 (-)EnsemblGRCm38mm10GRCm38
MGSCv37719,842,278 - 19,857,203 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,416,239 - 18,431,669 (-)NCBIMGSCv36mm8
Celera716,669,928 - 16,684,971 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.51NCBI
Vasp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557421,911 - 34,197 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495557421,569 - 33,705 (+)NCBIChiLan1.0ChiLan1.0
VASP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,668,472 - 51,688,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,540,746 - 53,560,217 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,457,222 - 42,476,688 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,053,567 - 51,072,551 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,053,567 - 51,072,553 (+)Ensemblpanpan1.1panPan2
VASP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,050,154 - 110,063,125 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,050,154 - 110,062,827 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,534,415 - 109,547,108 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,582,754 - 110,595,760 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,582,757 - 110,595,733 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,258,575 - 110,271,274 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,892,681 - 109,905,376 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,762,040 - 110,774,746 (-)NCBIUU_Cfam_GSD_1.0
LOC101973767
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,575,109 - 17,597,696 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,923,602 - 1,928,630 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,923,172 - 1,945,046 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VASP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,872,812 - 51,886,724 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,872,810 - 51,886,729 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
VASP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,954,212 - 38,974,680 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl638,954,014 - 38,975,108 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,575,539 - 18,596,231 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vasp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,619,134 - 7,630,943 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,619,211 - 7,631,576 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Vasp
35 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:63
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000022214
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat

Markers in Region
AA956278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,910,138 - 78,910,327 (+)MAPPERmRatBN7.2
Rnor_6.0180,170,738 - 80,170,926NCBIRnor6.0
Rnor_5.0181,437,221 - 81,437,409UniSTSRnor5.0
RGSC_v3.4178,621,618 - 78,621,806UniSTSRGSC3.4
Celera173,372,456 - 73,372,644UniSTS
RH 3.4 Map1818.2UniSTS
Cytogenetic Map1q21UniSTS
BF405517  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,912,681 - 78,912,786 (+)MAPPERmRatBN7.2
Rnor_6.0180,173,281 - 80,173,385NCBIRnor6.0
Rnor_5.0181,439,764 - 81,439,868UniSTSRnor5.0
RGSC_v3.4178,624,161 - 78,624,265UniSTSRGSC3.4
Celera173,374,999 - 73,375,103UniSTS
RH 3.4 Map1818.3UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000022214   ⟹   ENSRNOP00000022214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,910,011 - 78,925,061 (-)Ensembl
Rnor_6.0 Ensembl180,170,619 - 80,185,882 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088676   ⟹   ENSRNOP00000074940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,910,020 - 78,918,140 (-)Ensembl
Rnor_6.0 Ensembl180,171,404 - 80,178,708 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096980   ⟹   ENSRNOP00000088421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,910,020 - 78,919,412 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107990   ⟹   ENSRNOP00000089122
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,910,020 - 78,919,412 (-)Ensembl
RefSeq Acc Id: NM_001108475   ⟹   NP_001101945
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,032 - 88,052,955 (-)NCBI
mRatBN7.2178,910,015 - 78,924,940 (-)NCBI
Rnor_6.0180,170,614 - 80,185,882 (-)NCBI
Rnor_5.0181,437,091 - 81,452,900 (-)NCBI
RGSC_v3.4178,621,494 - 78,636,762 (-)RGD
Celera173,372,332 - 73,387,227 (-)RGD
Sequence:
RefSeq Acc Id: XM_039081727   ⟹   XP_038937655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,468 (-)NCBI
mRatBN7.2178,910,009 - 78,924,454 (-)NCBI
RefSeq Acc Id: XM_039081733   ⟹   XP_038937661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,053,782 (-)NCBI
mRatBN7.2178,910,009 - 78,925,789 (-)NCBI
RefSeq Acc Id: XM_039081738   ⟹   XP_038937666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,468 (-)NCBI
mRatBN7.2178,910,009 - 78,924,687 (-)NCBI
RefSeq Acc Id: XM_039081741   ⟹   XP_038937669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,469 (-)NCBI
mRatBN7.2178,910,009 - 78,924,692 (-)NCBI
RefSeq Acc Id: XM_039081742   ⟹   XP_038937670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,053,783 (-)NCBI
mRatBN7.2178,910,009 - 78,925,791 (-)NCBI
RefSeq Acc Id: XM_039081746   ⟹   XP_038937674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,470 (-)NCBI
mRatBN7.2178,910,009 - 78,924,694 (-)NCBI
RefSeq Acc Id: XR_005487868
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,468 (-)NCBI
mRatBN7.2178,910,009 - 78,924,454 (-)NCBI
RefSeq Acc Id: XR_010054316
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,053,782 (-)NCBI
RefSeq Acc Id: XR_010054317
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,038,026 - 88,052,468 (-)NCBI
RefSeq Acc Id: NP_001101945   ⟸   NM_001108475
- UniProtKB: B5DEX4 (UniProtKB/TrEMBL),   A0A8I6A7U4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022214   ⟸   ENSRNOT00000022214
Ensembl Acc Id: ENSRNOP00000074940   ⟸   ENSRNOT00000088676
RefSeq Acc Id: XP_038937670   ⟸   XM_039081742
- Peptide Label: isoform X5
- UniProtKB: A6J8L5 (UniProtKB/TrEMBL),   A6J8L6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937661   ⟸   XM_039081733
- Peptide Label: isoform X2
- UniProtKB: F7EWC1 (UniProtKB/TrEMBL),   A6J8L6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937674   ⟸   XM_039081746
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A7U4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937669   ⟸   XM_039081741
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A7U4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937666   ⟸   XM_039081738
- Peptide Label: isoform X3
- UniProtKB: A6J8L6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038937655   ⟸   XM_039081727
- Peptide Label: isoform X1
- UniProtKB: A6J8L6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000089122   ⟸   ENSRNOT00000107990
Ensembl Acc Id: ENSRNOP00000088421   ⟸   ENSRNOT00000096980
Protein Domains
WH1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9C0-F1-model_v2 AlphaFold A0A0G2K9C0 1-375 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689765
Promoter ID:EPDNEW_R290
Type:multiple initiation site
Name:Vasp_1
Description:vasodilator-stimulated phosphoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0180,185,768 - 80,185,828EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311542 AgrOrtholog
BioCyc Gene G2FUF-60518 BioCyc
Ensembl Genes ENSRNOG00000016367 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022214.8 UniProtKB/TrEMBL
  ENSRNOT00000088676.2 UniProtKB/TrEMBL
  ENSRNOT00000096980.1 UniProtKB/TrEMBL
  ENSRNOT00000107990.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro EVH1 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Vasodilator_phosphoprotein UniProtKB/TrEMBL
  VASP_sf UniProtKB/TrEMBL
  VASP_tetra UniProtKB/TrEMBL
KEGG Report rno:361517 UniProtKB/TrEMBL
NCBI Gene 361517 ENTREZGENE
PANTHER PTHR11202:SF12 UniProtKB/TrEMBL
  SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam VASP_tetra UniProtKB/TrEMBL
  WH1 UniProtKB/TrEMBL
PhenoGen Vasp PhenoGen
PIRSF Vasodilator_Phospo UniProtKB/TrEMBL
PROSITE WH1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016367 RatGTEx
SMART WH1 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF118370 UniProtKB/TrEMBL
UniProt A0A0G2K9C0_RAT UniProtKB/TrEMBL
  A0A8I6A7U4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAX7_RAT UniProtKB/TrEMBL
  A6J8L5 ENTREZGENE, UniProtKB/TrEMBL
  A6J8L6 ENTREZGENE, UniProtKB/TrEMBL
  B5DEX4 ENTREZGENE, UniProtKB/TrEMBL
  F7EWC1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Vasp  vasodilator-stimulated phosphoprotein   Vasp_predicted  vasodilator-stimulated phosphoprotein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Vasp_predicted  vasodilator-stimulated phosphoprotein (predicted)      Symbol and Name status set to approved 70820 APPROVED