VASP (vasodilator stimulated phosphoprotein) - Rat Genome Database

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Gene: VASP (vasodilator stimulated phosphoprotein) Chlorocebus sabaeus
Analyze
Symbol: VASP
Name: vasodilator stimulated phosphoprotein
RGD ID: 18602845
Description: ENCODES a protein that exhibits actin binding (inferred); profilin binding (inferred); SH3 domain binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); axon guidance (ortholog); neural tube closure (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); filopodium (ortholog); focal adhesion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103234868; vasodilator-stimulated phosphoprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,954,212 - 38,974,680 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl638,954,014 - 38,975,108 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,575,539 - 18,596,231 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
VASP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,954,212 - 38,974,680 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl638,954,014 - 38,975,108 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,575,539 - 18,596,231 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
VASP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,507,479 - 45,526,983 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,506,579 - 45,526,989 (+)EnsemblGRCh38hg38GRCh38
GRCh371946,010,737 - 46,030,241 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,702,528 - 50,722,081 (+)NCBINCBI36Build 36hg18NCBI36
Build 341950,702,527 - 50,722,078NCBI
Celera1942,816,794 - 42,836,352 (+)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,440,143 - 42,459,463 (+)NCBIHuRef
CHM1_11946,013,932 - 46,033,484 (+)NCBICHM1_1
T2T-CHM13v2.01948,334,741 - 48,354,257 (+)NCBIT2T-CHM13v2.0
Vasp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,990,854 - 19,005,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,990,854 - 19,005,742 (-)EnsemblGRCm39 Ensembl
GRCm38719,256,929 - 19,271,854 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,256,929 - 19,271,817 (-)EnsemblGRCm38mm10GRCm38
MGSCv37719,842,278 - 19,857,203 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,416,239 - 18,431,669 (-)NCBIMGSCv36mm8
Celera716,669,928 - 16,684,971 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.51NCBI
Vasp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,038,026 - 88,053,783 (-)NCBIGRCr8
mRatBN7.2178,910,009 - 78,925,791 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,910,011 - 78,925,061 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,299,066 - 84,313,957 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,856,629 - 92,871,541 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,054,149 - 86,069,040 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,170,608 - 80,185,882 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,170,619 - 80,185,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,437,091 - 81,452,900 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,621,494 - 78,636,762 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,699,598 - 78,715,028 (-)NCBI
Celera173,372,332 - 73,387,227 (-)NCBICelera
Cytogenetic Map1q21NCBI
Vasp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557421,911 - 34,197 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495557421,569 - 33,705 (+)NCBIChiLan1.0ChiLan1.0
VASP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,668,472 - 51,688,796 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,540,746 - 53,560,217 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,457,222 - 42,476,688 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,053,567 - 51,072,551 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,053,567 - 51,072,553 (+)Ensemblpanpan1.1panPan2
VASP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,050,154 - 110,063,125 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,050,154 - 110,062,827 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,534,415 - 109,547,108 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,582,754 - 110,595,760 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,582,757 - 110,595,733 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,258,575 - 110,271,274 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,892,681 - 109,905,376 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,762,040 - 110,774,746 (-)NCBIUU_Cfam_GSD_1.0
LOC101973767
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,575,109 - 17,597,696 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,923,602 - 1,928,630 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,923,172 - 1,945,046 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VASP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,872,812 - 51,886,724 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,872,810 - 51,886,729 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Vasp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,619,134 - 7,630,943 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,619,211 - 7,631,576 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 20 20
Low 40
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000001199   ⟹   ENSCSAP00000014874
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl638,954,014 - 38,975,108 (+)Ensembl
RefSeq Acc Id: XM_007997225   ⟹   XP_007995416
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1638,954,215 - 38,974,680 (+)NCBI
Vero_WHO_p1.0NW_02366607318,575,546 - 18,596,231 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007997226   ⟹   XP_007995417
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1638,954,212 - 38,974,680 (+)NCBI
Vero_WHO_p1.0NW_02366607318,575,539 - 18,596,231 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007997227   ⟹   XP_007995418
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1638,954,212 - 38,974,680 (+)NCBI
Vero_WHO_p1.0NW_02366607318,575,541 - 18,596,231 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007995416 (Get FASTA)   NCBI Sequence Viewer  
  XP_007995417 (Get FASTA)   NCBI Sequence Viewer  
  XP_007995418 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000014874
  ENSCSAP00000014874.1
Reference Protein Sequences
RefSeq Acc Id: XP_007995418   ⟸   XM_007997227
- Peptide Label: isoform X3
RefSeq Acc Id: XP_007995417   ⟸   XM_007997226
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007995416   ⟸   XM_007997225
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S1Y5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000014874   ⟸   ENSCSAT00000001199


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003169 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001199.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  VASP/EVL UniProtKB/TrEMBL
  VASP_sf UniProtKB/TrEMBL
  VASP_tetra UniProtKB/TrEMBL
  WH1/EVH1_dom UniProtKB/TrEMBL
KEGG Report csab:103234868 UniProtKB/TrEMBL
NCBI Gene VASP ENTREZGENE
PANTHER PTHR11202:SF12 UniProtKB/TrEMBL
  SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam VASP_tetra UniProtKB/TrEMBL
  WH1 UniProtKB/TrEMBL
PIRSF Vasodilator_Phospo UniProtKB/TrEMBL
PROSITE WH1 UniProtKB/TrEMBL
SMART WH1 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF118370 UniProtKB/TrEMBL
UniProt A0A0D9S1Y5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-09 VASP  vasodilator stimulated phosphoprotein  LOC103234868  vasodilator stimulated phosphoprotein  Symbol and/or name change 5135510 APPROVED
2020-12-08 LOC103234868  vasodilator stimulated phosphoprotein  VASP  vasodilator stimulated phosphoprotein  Symbol and/or name change 5135510 APPROVED