Coro2a (coronin 2A) - Rat Genome Database

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Gene: Coro2a (coronin 2A) Rattus norvegicus
Analyze
Symbol: Coro2a
Name: coronin 2A
RGD ID: 1309719
Description: Predicted to enable actin filament binding activity. Predicted to be located in brush border. Predicted to be part of transcription repressor complex. Orthologous to human CORO2A (coronin 2A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: coronin, actin binding protein 2A; coronin-2A; LOC313235
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,623,820 - 65,677,483 (-)NCBIGRCr8
mRatBN7.2560,825,630 - 60,881,917 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,828,247 - 60,859,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx562,799,206 - 62,829,895 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,618,572 - 64,649,265 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,587,986 - 64,618,675 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0562,154,526 - 62,210,797 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl562,156,839 - 62,187,930 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0566,682,213 - 66,737,392 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4563,121,905 - 63,152,843 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1563,122,086 - 63,153,022 (-)NCBI
Celera559,389,825 - 59,420,508 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
8-Br-cAMP  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
cadmium dichloride  (EXP)
camptothecin  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Nutlin-3  (ISO)
ozone  (ISO)
panobinostat  (ISO)
PCB138  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12628926   PMID:19654210   PMID:22114352   PMID:24625528  


Genomics

Comparative Map Data
Coro2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,623,820 - 65,677,483 (-)NCBIGRCr8
mRatBN7.2560,825,630 - 60,881,917 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,828,247 - 60,859,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx562,799,206 - 62,829,895 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,618,572 - 64,649,265 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,587,986 - 64,618,675 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0562,154,526 - 62,210,797 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl562,156,839 - 62,187,930 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0566,682,213 - 66,737,392 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4563,121,905 - 63,152,843 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1563,122,086 - 63,153,022 (-)NCBI
Celera559,389,825 - 59,420,508 (-)NCBICelera
Cytogenetic Map5q22NCBI
CORO2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38998,120,975 - 98,192,637 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl998,120,975 - 98,192,637 (-)EnsemblGRCh38hg38GRCh38
GRCh379100,883,257 - 100,954,919 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36999,926,294 - 99,994,743 (-)NCBINCBI36Build 36hg18NCBI36
Build 34997,966,032 - 98,034,477NCBI
Celera971,397,550 - 71,469,269 (-)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef970,483,409 - 70,555,156 (-)NCBIHuRef
CHM1_19101,029,674 - 101,101,387 (-)NCBICHM1_1
T2T-CHM13v2.09110,292,922 - 110,364,586 (-)NCBIT2T-CHM13v2.0
Coro2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39446,536,937 - 46,601,929 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl446,536,937 - 46,602,202 (-)EnsemblGRCm39 Ensembl
GRCm38446,536,937 - 46,601,929 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl446,536,937 - 46,602,202 (-)EnsemblGRCm38mm10GRCm38
MGSCv37446,549,809 - 46,579,312 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36446,558,659 - 46,587,540 (-)NCBIMGSCv36mm8
Celera446,555,568 - 46,613,230 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map424.87NCBI
Coro2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541927,348,452 - 27,388,965 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541927,323,164 - 27,386,488 (+)NCBIChiLan1.0ChiLan1.0
CORO2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21141,265,137 - 41,337,032 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1941,267,525 - 41,339,409 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0969,210,625 - 69,282,434 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1997,335,021 - 97,403,255 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl997,335,026 - 97,368,204 (-)Ensemblpanpan1.1panPan2
CORO2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11155,345,577 - 55,400,092 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1155,345,934 - 55,372,374 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1153,778,976 - 53,833,540 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01156,457,510 - 56,512,403 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1156,459,945 - 56,512,809 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11154,953,123 - 55,007,725 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01154,983,784 - 55,038,657 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01155,680,250 - 55,729,539 (-)NCBIUU_Cfam_GSD_1.0
Coro2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947170,272,327 - 170,316,358 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365246,820,063 - 6,848,371 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365246,819,641 - 6,845,854 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CORO2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,947,301 - 240,000,918 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,947,299 - 240,000,964 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21268,117,471 - 268,171,600 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CORO2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11241,226,972 - 41,294,742 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1241,227,349 - 41,295,468 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603838,266,023 - 38,333,941 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Coro2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248252,712,489 - 2,749,806 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248252,682,632 - 2,749,202 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Coro2a
357 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:78
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000011787
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 48 113 91 90 59 25 59 6 215 95 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000011787   ⟹   ENSRNOP00000011787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl560,828,247 - 60,859,035 (-)Ensembl
Rnor_6.0 Ensembl562,157,149 - 62,187,930 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089789   ⟹   ENSRNOP00000072816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl562,156,839 - 62,186,372 (-)Ensembl
RefSeq Acc Id: NM_001012101   ⟹   NP_001012101
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,623,820 - 65,654,602 (-)NCBI
mRatBN7.2560,828,244 - 60,859,035 (-)NCBI
Rnor_6.0562,157,148 - 62,187,930 (-)NCBI
Rnor_5.0566,682,213 - 66,737,392 (-)NCBI
RGSC_v3.4563,121,905 - 63,152,843 (-)RGD
Celera559,389,825 - 59,420,508 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006238058   ⟹   XP_006238120
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,623,820 - 65,677,483 (-)NCBI
mRatBN7.2560,825,630 - 60,881,917 (-)NCBI
Rnor_6.0562,154,526 - 62,210,797 (-)NCBI
Rnor_5.0566,682,213 - 66,737,392 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593364   ⟹   XP_017448853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,623,820 - 65,654,655 (-)NCBI
mRatBN7.2560,825,630 - 60,859,539 (-)NCBI
Rnor_6.0562,154,526 - 62,189,227 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109864   ⟹   XP_038965792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,623,820 - 65,654,621 (-)NCBI
mRatBN7.2560,825,630 - 60,859,539 (-)NCBI
RefSeq Acc Id: XM_063287629   ⟹   XP_063143699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,623,820 - 65,655,208 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001012101 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238120 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448853 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965792 (Get FASTA)   NCBI Sequence Viewer  
  XP_063143699 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79209 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011787.7
RefSeq Acc Id: NP_001012101   ⟸   NM_001012101
- UniProtKB: A0A0G2QC56 (UniProtKB/TrEMBL),   A6IJC5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238120   ⟸   XM_006238058
- Peptide Label: isoform X2
- UniProtKB: Q6AY36 (UniProtKB/TrEMBL),   F1LSP7 (UniProtKB/TrEMBL),   A6IJC5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448853   ⟸   XM_017593364
- Peptide Label: isoform X1
- UniProtKB: A0A0G2QC56 (UniProtKB/TrEMBL),   A6IJC5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011787   ⟸   ENSRNOT00000011787
Ensembl Acc Id: ENSRNOP00000072816   ⟸   ENSRNOT00000089789
RefSeq Acc Id: XP_038965792   ⟸   XM_039109864
- Peptide Label: isoform X2
- UniProtKB: F1LSP7 (UniProtKB/TrEMBL),   Q6AY36 (UniProtKB/TrEMBL),   A6IJC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143699   ⟸   XM_063287629
- Peptide Label: isoform X2
- UniProtKB: F1LSP7 (UniProtKB/TrEMBL),   Q6AY36 (UniProtKB/TrEMBL)
Protein Domains
DUF1899

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2QC56-F1-model_v2 AlphaFold A0A0G2QC56 1-543 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693716
Promoter ID:EPDNEW_R4240
Type:multiple initiation site
Name:Coro2a_1
Description:coronin 2A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0562,187,923 - 62,187,983EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309719 AgrOrtholog
BioCyc Gene G2FUF-41402 BioCyc
Ensembl Genes ENSRNOG00000008901 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011787.8 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131801 IMAGE-MGC_LOAD
InterPro Coronin UniProtKB/TrEMBL
  DUF1899 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:313235 UniProtKB/TrEMBL
MGC_CLONE MGC:94271 IMAGE-MGC_LOAD
NCBI Gene 313235 ENTREZGENE
PANTHER Coronin UniProtKB/TrEMBL
  PTHR10856:SF2 UniProtKB/TrEMBL
Pfam DUF1899 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
  WD40_4 UniProtKB/TrEMBL
PhenoGen Coro2a PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008901 RatGTEx
SMART DUF1899 UniProtKB/TrEMBL
  DUF1900 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A0G2QC56 ENTREZGENE, UniProtKB/TrEMBL
  A6IJC5 ENTREZGENE, UniProtKB/TrEMBL
  F1LSP7 ENTREZGENE
  Q6AY36 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LSP7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-20 Coro2a  coronin 2A  Coro2a  coronin, actin binding protein 2A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Coro2a  coronin, actin binding protein 2A  Coro2a_predicted  coronin, actin binding protein 2A (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Coro2a_predicted  coronin, actin binding protein 2A (predicted)      Symbol and Name status set to approved 70820 APPROVED