Isy1 (ISY1 splicing factor homolog) - Rat Genome Database

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Gene: Isy1 (ISY1 splicing factor homolog) Rattus norvegicus
Analyze
Symbol: Isy1
Name: ISY1 splicing factor homolog
RGD ID: 1307688
Description: Predicted to be involved in generation of catalytic spliceosome for second transesterification step and mRNA 3'-splice site recognition. Predicted to be located in nucleus. Predicted to be part of Prp19 complex and spliceosomal complex. Orthologous to several human genes including ISY1 (ISY1 splicing factor homolog); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ISY1 splicing factor homolog (S. cerevisiae); Isy1-rab43; ISY1-RAB43 readthrough; LOC362394; pre-mRNA-splicing factor ISY1 homolog; RGD1307688; similar to RIKEN cDNA 5830446M03
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84121,833,870 - 121,854,561 (-)NCBIGRCr8
mRatBN7.24120,276,535 - 120,297,227 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4120,276,292 - 120,297,188 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4125,755,473 - 125,776,233 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04121,530,265 - 121,551,018 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04120,154,502 - 120,175,256 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04119,721,659 - 119,742,349 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4119,721,660 - 119,742,349 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04184,972,994 - 184,993,684 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44122,006,785 - 122,027,475 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14122,251,266 - 122,271,956 (-)NCBI
Celera4109,237,067 - 109,257,757 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Splicing and beyond: the many faces of the Prp19 complex. Chanarat S and Strasser K, Biochim Biophys Acta. 2013 Oct;1833(10):2126-34. doi: 10.1016/j.bbamcr.2013.05.023. Epub 2013 Jun 3.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11991638   PMID:15489334   PMID:22658674   PMID:29301961  


Genomics

Comparative Map Data
Isy1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84121,833,870 - 121,854,561 (-)NCBIGRCr8
mRatBN7.24120,276,535 - 120,297,227 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4120,276,292 - 120,297,188 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4125,755,473 - 125,776,233 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04121,530,265 - 121,551,018 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04120,154,502 - 120,175,256 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04119,721,659 - 119,742,349 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4119,721,660 - 119,742,349 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04184,972,994 - 184,993,684 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44122,006,785 - 122,027,475 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14122,251,266 - 122,271,956 (-)NCBI
Celera4109,237,067 - 109,257,757 (-)NCBICelera
Cytogenetic Map4q34NCBI
ISY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383129,127,415 - 129,161,063 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3129,127,415 - 129,161,063 (-)EnsemblGRCh38hg38GRCh38
GRCh373128,846,258 - 128,879,906 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363130,330,925 - 130,362,719 (-)NCBINCBI36Build 36hg18NCBI36
Celera3127,279,847 - 127,296,403 (-)NCBICelera
Cytogenetic Map3q21.3NCBI
HuRef3126,232,620 - 126,266,455 (-)NCBIHuRef
CHM1_13128,809,709 - 128,843,507 (-)NCBICHM1_1
T2T-CHM13v2.03131,872,317 - 131,905,969 (-)NCBIT2T-CHM13v2.0
Isy1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,795,429 - 87,815,723 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl687,791,251 - 87,815,780 (-)EnsemblGRCm39 Ensembl
GRCm38687,818,447 - 87,838,923 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,814,269 - 87,838,798 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,768,441 - 87,788,753 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36687,784,088 - 87,804,400 (-)NCBIMGSCv36mm8
Celera689,755,774 - 89,776,088 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map639.13NCBI
Isy1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542913,511,914 - 13,527,516 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542913,513,191 - 13,527,516 (-)NCBIChiLan1.0ChiLan1.0
ISY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22127,062,204 - 127,098,841 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13127,066,927 - 127,100,331 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03126,187,354 - 126,219,355 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13133,545,726 - 133,575,974 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3133,545,726 - 133,575,974 (-)Ensemblpanpan1.1panPan2
ISY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1202,945,636 - 2,972,245 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl202,945,720 - 2,972,245 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha202,982,811 - 3,008,961 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0202,966,468 - 2,993,064 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl202,966,789 - 2,996,303 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1202,686,460 - 2,712,607 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0203,009,520 - 3,035,724 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0202,973,956 - 3,000,161 (+)NCBIUU_Cfam_GSD_1.0
LOC102162880
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1371,599,237 - 71,622,840 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11371,601,737 - 71,622,835 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21379,186,720 - 79,207,558 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ISY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12251,905,564 - 51,940,705 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2251,907,290 - 51,938,847 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041114,430,973 - 114,474,500 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Isy1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624943968,193 - 984,683 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Isy1
60 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:42
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000013571
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4116179486151161268Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4120260281147278687Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105789505150789505Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4106805662151805662Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4119463257147278687Rat

Markers in Region
RH138640  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24120,288,742 - 120,288,990 (+)MAPPERmRatBN7.2
Rnor_6.04119,733,866 - 119,734,113NCBIRnor6.0
Rnor_5.04184,985,201 - 184,985,448UniSTSRnor5.0
RGSC_v3.44122,018,992 - 122,019,239UniSTSRGSC3.4
Celera4109,249,274 - 109,249,521UniSTS
RH 3.4 Map4712.5UniSTS
Cytogenetic Map4q34UniSTS
RH139686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24120,276,375 - 120,276,525 (+)MAPPERmRatBN7.2
Rnor_6.04119,721,500 - 119,721,649NCBIRnor6.0
Rnor_5.04184,972,835 - 184,972,984UniSTSRnor5.0
RGSC_v3.44122,006,626 - 122,006,775UniSTSRGSC3.4
Celera4109,236,908 - 109,237,057UniSTS
RH 3.4 Map4711.8UniSTS
Cytogenetic Map4q34UniSTS
BI274365  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24120,297,462 - 120,297,587 (+)MAPPERmRatBN7.2
Rnor_6.04119,742,585 - 119,742,709NCBIRnor6.0
Rnor_5.04184,993,920 - 184,994,044UniSTSRnor5.0
RGSC_v3.44122,027,711 - 122,027,835UniSTSRGSC3.4
Celera4109,257,993 - 109,258,117UniSTS
RH 3.4 Map4711.9UniSTS
Cytogenetic Map4q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000013571   ⟹   ENSRNOP00000013571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4120,276,292 - 120,297,188 (-)Ensembl
Rnor_6.0 Ensembl4119,721,660 - 119,742,349 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093886   ⟹   ENSRNOP00000078536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4120,276,302 - 120,297,121 (-)Ensembl
RefSeq Acc Id: NM_001014188   ⟹   NP_001014210
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84121,833,870 - 121,854,561 (-)NCBI
mRatBN7.24120,276,535 - 120,297,227 (-)NCBI
Rnor_6.04119,721,659 - 119,742,349 (-)NCBI
Rnor_5.04184,972,994 - 184,993,684 (-)NCBI
RGSC_v3.44122,006,785 - 122,027,475 (-)RGD
Celera4109,237,067 - 109,257,757 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001014210 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79119 (Get FASTA)   NCBI Sequence Viewer  
  EDL91288 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013571.4
  ENSRNOP00000078536.1
  ENSRNOP00055018056
  ENSRNOP00060034851
  ENSRNOP00065019554
GenBank Protein Q6AYB3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001014210   ⟸   NM_001014188
- UniProtKB: Q6AYB3 (UniProtKB/Swiss-Prot),   A6IB20 (UniProtKB/TrEMBL),   A0A8I5ZL45 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013571   ⟸   ENSRNOT00000013571
Ensembl Acc Id: ENSRNOP00000078536   ⟸   ENSRNOT00000093886

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYB3-F1-model_v2 AlphaFold Q6AYB3 1-284 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693225
Promoter ID:EPDNEW_R3748
Type:initiation region
Name:Isy1_1
Description:ISY1 splicing factor homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04119,742,401 - 119,742,461EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307688 AgrOrtholog
BioCyc Gene G2FUF-43851 BioCyc
Ensembl Genes ENSRNOG00000010021 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055012975 UniProtKB/Swiss-Prot
  ENSRNOG00060024260 UniProtKB/Swiss-Prot
  ENSRNOG00065015091 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013571.6 UniProtKB/Swiss-Prot
  ENSRNOT00000093886.1 UniProtKB/TrEMBL
  ENSRNOT00055022227 UniProtKB/Swiss-Prot
  ENSRNOT00060042025 UniProtKB/Swiss-Prot
  ENSRNOT00065024984 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7126525 IMAGE-MGC_LOAD
InterPro Helix_hairpin_bin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Isy1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Isy1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362394 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94120 IMAGE-MGC_LOAD
NCBI Gene 362394 ENTREZGENE
PANTHER PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13021 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Isy1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Isy1 PhenoGen
RatGTEx ENSRNOG00000010021 RatGTEx
  ENSRNOG00055012975 RatGTEx
  ENSRNOG00060024260 RatGTEx
  ENSRNOG00065015091 RatGTEx
Superfamily-SCOP SSF140102 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZL45 ENTREZGENE, UniProtKB/TrEMBL
  A6IB20 ENTREZGENE, UniProtKB/TrEMBL
  ISY1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-09 Isy1  ISY1 splicing factor homolog  Isy1  ISY1 splicing factor homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-11-26 Isy1  ISY1 splicing factor homolog (S. cerevisiae)  Isy1-rab43  ISY1-RAB43 readthrough  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-18 Isy1-rab43  ISY1-RAB43 readthrough  Isy1  ISY1 splicing factor homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Isy1  ISY1 splicing factor homolog (S. cerevisiae)  RGD1307688  similar to RIKEN cDNA 5830446M03  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1307688  similar to RIKEN cDNA 5830446M03  RGD1307688_predicted  similar to RIKEN cDNA 5830446M03 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1307688_predicted  similar to RIKEN cDNA 5830446M03 (predicted)  LOC362394_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362394_predicted  similar to RIKEN cDNA 5830446M03 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL