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Gene: ISY1 (ISY1 splicing factor homolog) Homo sapiens
Symbol: ISY1
Name: ISY1 splicing factor homolog
Description: Exhibits RNA binding activity. Predicted to contribute to first spliceosomal transesterification activity. Involved in mRNA splicing, via spliceosome. Localizes to the U2-type catalytic step 1 spliceosome and catalytic step 2 spliceosome; PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2-methylcholine; copper atom; copper(0).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fSAP33; functional spliceosome-associated protein 33; KIAA1160; pre-mRNA-splicing factor ISY1 homolog
Mus musculus (house mouse) : Isy1 (ISY1 splicing factor homolog)  MGI  Alliance
Rattus norvegicus (Norway rat) : Isy1 (ISY1 splicing factor homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Isy1 (ISY1 splicing factor homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : ISY1 (ISY1 splicing factor homolog)
Canis lupus familiaris (dog) : ISY1 (ISY1 splicing factor homolog)
Chlorocebus sabaeus (African green monkey) : ISY1 (ISY1 splicing factor homolog)
Heterocephalus glaber (naked mole-rat) : Isy1 (ISY1 splicing factor homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl3129,127,415 - 129,161,293 (-)EnsemblGRCh38hg38GRCh38
GRCh383129,127,415 - 129,161,063 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373128,846,259 - 128,880,409 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363130,330,925 - 130,362,719 (-)NCBINCBI36hg18NCBI36
Celera3127,279,847 - 127,296,403 (-)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3126,232,620 - 126,266,455 (-)NCBIHuRef
CHM1_13128,809,709 - 128,843,507 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ISY1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606526
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.