BRCA1 (BRCA1 DNA repair associated) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: BRCA1 (BRCA1 DNA repair associated) Canis lupus familiaris
Analyze
Symbol: BRCA1
Name: BRCA1 DNA repair associated
RGD ID: 12124452
Description: ENCODES a protein that exhibits chromatin binding (ortholog); RNA polymerase binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN centrosome cycle (ortholog); chordate embryonic development (ortholog); DNA damage response (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; forkhead class A signaling pathway; homologous recombination pathway of double-strand break repair; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Animal Mammary Neoplasms (ortholog); bilateral breast cancer (ortholog); FOUND IN BRCA1-BARD1 complex (ortholog); chromosome (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BRCA1 homolog; BRCA1, DNA repair associated; breast and ovarian cancer susceptibility protein 1; breast cancer type 1 susceptibility protein homolog; RING-type E3 ubiquitin transferase BRCA1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1919,958,941 - 20,025,494 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl919,958,391 - 20,025,494 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha919,422,566 - 19,486,083 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0920,677,057 - 20,743,989 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,677,128 - 20,743,989 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,464,421 - 19,527,988 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,730,981 - 19,794,752 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,833,116 - 19,896,786 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View
adenoid cystic carcinoma  (ISO)
Animal Mammary Neoplasms  (ISO)
bilateral breast cancer  (ISO)
breast adenocarcinoma  (ISO)
breast cancer  (ISO)
Breast Cancer, Familial  (ISO)
breast carcinoma  (ISO)
breast ductal carcinoma  (ISO)
Breast Neoplasms  (ISO)
Burkitt lymphoma  (ISO)
carcinoma  (ISO)
cervical cancer  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chromosome Breakage  (ISO)
colon cancer  (ISO)
colon carcinoma  (ISO)
colorectal cancer  (ISO)
colorectal carcinoma  (ISO)
disease of cellular proliferation  (ISO)
ductal carcinoma in situ  (ISO)
dysgerminoma  (ISO)
endometrial carcinoma  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Mammary Neoplasms  (ISO)
Familial Pancreatic Carcinoma  (ISO)
Familial Prostate Cancer  (ISO)
Fanconi anemia complementation group A  (ISO)
Fanconi anemia complementation group S  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
hereditary mixed polyposis syndrome 1  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
hereditary spastic paraplegia 11  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
infant-type hemispheric glioma  (ISO)
invasive ductal carcinoma  (ISO)
lung cancer  (ISO)
lung non-small cell carcinoma  (ISO)
mouth disease  (ISO)
nasopharynx carcinoma  (ISO)
Neoplastic Cell Transformation  (ISO)
ovarian cancer  (ISO)
ovarian carcinoma  (ISO)
Ovarian Neoplasms  (ISO)
ovary serous adenocarcinoma  (ISO)
pancreatic cancer  (ISO)
pancreatic carcinoma  (ISO)
peritoneum cancer  (ISO)
periventricular nodular heterotopia  (ISO)
Premature Aging  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
punctate palmoplantar keratoderma type II  (ISO)
rhabdomyosarcoma  (ISO)
stomach cancer  (ISO)
stomach carcinoma  (ISO)
Triple Negative Breast Neoplasms  (ISO)
urinary bladder cancer  (ISO)
Urinary Bladder Neoplasm  (ISO)
uterine corpus cancer  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to indole-3-methanol  (IEA)
cellular response to ionizing radiation  (IEA)
cellular response to tumor necrosis factor  (IEA)
centrosome cycle  (ISO)
chordate embryonic development  (IBA,ISO)
chromosome segregation  (IEA)
DNA damage response  (IEA,ISO)
DNA damage tolerance  (IEA)
DNA recombination  (IEA)
DNA repair  (IEA)
DNA-templated transcription  (IEA)
double-strand break repair  (IEA)
double-strand break repair via homologous recombination  (IBA,IEA)
fatty acid biosynthetic process  (IEA)
fatty acid metabolic process  (IEA)
intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
lipid metabolic process  (IEA)
mitotic G2 DNA damage checkpoint signaling  (IBA,IEA)
mitotic G2/M transition checkpoint  (ISO)
negative regulation of cell growth  (IEA)
negative regulation of DNA-templated transcription  (IEA)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (IEA)
negative regulation of fatty acid biosynthetic process  (IEA,ISS)
negative regulation of gene expression via chromosomal CpG island methylation  (ISO)
negative regulation of intracellular estrogen receptor signaling pathway  (IEA)
negative regulation of reactive oxygen species metabolic process  (IEA)
positive regulation of angiogenesis  (IEA)
positive regulation of DNA repair  (IEA)
positive regulation of DNA-templated transcription  (IEA,ISS)
positive regulation of gene expression  (IEA)
positive regulation of protein import into nucleus  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,IEA)
positive regulation of vascular endothelial growth factor production  (IEA)
protein autoubiquitination  (IEA,ISS)
protein K6-linked ubiquitination  (IEA,ISS)
protein ubiquitination  (IEA)
random inactivation of X chromosome  (ISO)
regulation of cell cycle  (ISO)
regulation of transcription by RNA polymerase II  (IEA,ISS)
response to estradiol  (ISO)
response to genistein  (ISO)
response to ionizing radiation  (IEA)
response to lipid  (ISO)
response to nutrient  (ISO)

Cellular Component

References
Additional References at PubMed
PMID:8872468   PMID:10690375   PMID:17611353   PMID:19887619   PMID:22301074   PMID:24122022   PMID:26156012   PMID:26679809   PMID:30032202  


Genomics

Comparative Map Data
BRCA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1919,958,941 - 20,025,494 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl919,958,391 - 20,025,494 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha919,422,566 - 19,486,083 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0920,677,057 - 20,743,989 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,677,128 - 20,743,989 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,464,421 - 19,527,988 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,730,981 - 19,794,752 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,833,116 - 19,896,786 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
BRCA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381743,044,295 - 43,170,327 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1743,044,292 - 43,170,245 (-)Ensemblhg38GRCh38
GRCh371741,196,312 - 41,322,344 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,449,840 - 38,530,994 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341738,449,843 - 38,530,934NCBI
Celera1737,853,171 - 37,934,354 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1736,962,663 - 37,043,809 (-)NCBIHuRef
CHM1_11741,431,851 - 41,513,018 (-)NCBICHM1_1
T2T-CHM13v2.01743,902,857 - 44,029,084 (-)NCBIT2T-CHM13v2.0
Brca1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,379,587 - 101,442,808 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,379,590 - 101,442,781 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3811101,488,761 - 101,551,955 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,488,764 - 101,551,955 (-)Ensemblmm10GRCm38
MGSCv3711101,350,078 - 101,413,269 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3611101,304,854 - 101,365,210 (-)NCBIMGSCv36mm8
Celera11113,175,987 - 113,239,169 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1165.18NCBI
Brca1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,917,693 - 86,978,012 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1086,917,693 - 86,977,763 (-)EnsemblGRCr8
mRatBN7.21086,417,441 - 86,477,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,418,000 - 86,477,304 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1091,454,623 - 91,513,795 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,930,035 - 90,990,102 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,323,338 - 86,383,395 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1090,067,034 - 90,127,104 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive1090,798,647 - 90,858,722 (-)NCBILyon_Normotensive
Lyon_Hypertensive1092,243,738 - 92,303,813 (-)NCBILyon_Hypertensive
F344_StmMcwi1092,353,401 - 92,413,476 (-)NCBIF344_StmMcwi
Rnor_6.01089,394,821 - 89,455,093 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,394,803 - 89,454,681 (-)Ensemblrn6Rnor6.0
Rnor_5.01089,192,653 - 89,252,760 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41090,513,630 - 90,572,676 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1085,140,052 - 85,200,670 (-)NCBICelera
RGSC_v3.11090,527,999 - 90,587,046 (-)NCBI
Cytogenetic Map10q31NCBI
Brca1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,819,023 - 16,855,528 (-)Ensembl
ChiLan1.0NW_00495545116,819,463 - 16,870,780 (-)NCBIChiLan1.0ChiLan1.0
BRCA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21921,865,798 - 21,957,438 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11723,755,123 - 23,836,219 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,197,946 - 14,279,064 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,429,601 - 14,506,815 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,428,526 - 14,506,815 (+)EnsemblpanPan2panpan1.1
Brca1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,272,096 - 19,340,929 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,735,516 - 17,801,454 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,735,444 - 17,801,456 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRCA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1219,786,020 - 19,854,668 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11219,788,087 - 19,854,515 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,028,878 - 20,093,800 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BRCA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,162,827 - 63,243,928 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607733,932,799 - 34,042,352 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brca1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,188,136 - 1,241,964 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247951,186,043 - 1,238,986 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Brca1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1960,775,195 - 60,835,480 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in BRCA1
530 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001013416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005624312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005624313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005624314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014116455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014116457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014116458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014116459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002629653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005431678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF159258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF250234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY136626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM458140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U50709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000023190   ⟹   ENSCAFP00000021534
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl919,959,766 - 20,022,251 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000043953   ⟹   ENSCAFP00000037946
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl919,959,766 - 20,025,494 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000065506   ⟹   ENSCAFP00000048759
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl919,959,443 - 20,025,494 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000069987   ⟹   ENSCAFP00000062284
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl919,959,766 - 20,025,494 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000070371   ⟹   ENSCAFP00000044212
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl920,021,450 - 20,024,368 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000071681   ⟹   ENSCAFP00000055065
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl919,958,391 - 20,025,494 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000076152   ⟹   ENSCAFP00000054724
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl919,959,766 - 20,022,145 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845010804   ⟹   ENSCAFP00845008432
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl920,677,128 - 20,743,989 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845010832   ⟹   ENSCAFP00845008453
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl920,677,128 - 20,740,738 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845010922   ⟹   ENSCAFP00845008522
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl920,677,897 - 20,706,983 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845010974   ⟹   ENSCAFP00845008565
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl920,739,943 - 20,742,865 (+)Ensembl
RefSeq Acc Id: NM_001013416   ⟹   NP_001013434
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1919,960,910 - 20,024,390 (+)NCBI
Dog10K_Boxer_Tasha919,422,566 - 19,486,083 (+)NCBI
ROS_Cfam_1.0920,679,041 - 20,742,887 (+)NCBI
UMICH_Zoey_3.1919,464,421 - 19,527,988 (+)NCBI
UNSW_CanFamBas_1.0919,730,981 - 19,794,752 (+)NCBI
UU_Cfam_GSD_1.0919,833,116 - 19,896,786 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038674909   ⟹   XP_038530837
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,251 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674910   ⟹   XP_038530838
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,253 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674912   ⟹   XP_038530840
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,844 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674913   ⟹   XP_038530841
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,057 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674914   ⟹   XP_038530842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,844 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674915   ⟹   XP_038530843
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,058 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674916   ⟹   XP_038530844
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,846 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674917   ⟹   XP_038530845
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,846 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674918   ⟹   XP_038530846
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,240 - 20,740,886 (+)NCBI
RefSeq Acc Id: XM_038674919   ⟹   XP_038530847
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,283 - 20,743,989 (+)NCBI
RefSeq Acc Id: XM_038674920   ⟹   XP_038530848
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,284 - 20,743,989 (+)NCBI
RefSeq Acc Id: XR_005431678
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,677,240 - 20,741,324 (+)NCBI
RefSeq Acc Id: NP_001013434   ⟸   NM_001013416
- UniProtKB: Q95153 (UniProtKB/Swiss-Prot),   A0A8C0T715 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000044212   ⟸   ENSCAFT00000070371
Ensembl Acc Id: ENSCAFP00000062284   ⟸   ENSCAFT00000069987
Ensembl Acc Id: ENSCAFP00000037946   ⟸   ENSCAFT00000043953
Ensembl Acc Id: ENSCAFP00000054724   ⟸   ENSCAFT00000076152
Ensembl Acc Id: ENSCAFP00000021534   ⟸   ENSCAFT00000023190
Ensembl Acc Id: ENSCAFP00000048759   ⟸   ENSCAFT00000065506
Ensembl Acc Id: ENSCAFP00000055065   ⟸   ENSCAFT00000071681
RefSeq Acc Id: XP_038530841   ⟸   XM_038674913
- Peptide Label: isoform X3
- UniProtKB: A0A8C0RAM3 (UniProtKB/TrEMBL),   A0A8C0T715 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530843   ⟸   XM_038674915
- Peptide Label: isoform X4
- UniProtKB: A0A8C0RAP1 (UniProtKB/TrEMBL),   A0A8I3N406 (UniProtKB/TrEMBL),   A0A8C0T715 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530846   ⟸   XM_038674918
- Peptide Label: isoform X5
- UniProtKB: A0A8C0T715 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530837   ⟸   XM_038674909
- Peptide Label: isoform X1
- UniProtKB: A0A8C0T715 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530838   ⟸   XM_038674910
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T715 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530847   ⟸   XM_038674919
- Peptide Label: isoform X6
- UniProtKB: A0A8C0T776 (UniProtKB/TrEMBL),   A0A8I3MXX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530848   ⟸   XM_038674920
- Peptide Label: isoform X7
- UniProtKB: A0A8C0T776 (UniProtKB/TrEMBL),   A0A8I3MXX4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530842   ⟸   XM_038674914
- Peptide Label: isoform X3
- UniProtKB: A0A8C0RAM3 (UniProtKB/TrEMBL),   A0A8C0T715 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530840   ⟸   XM_038674912
- Peptide Label: isoform X3
- UniProtKB: A0A8C0RAM3 (UniProtKB/TrEMBL),   A0A8C0T715 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530845   ⟸   XM_038674917
- Peptide Label: isoform X4
- UniProtKB: A0A8C0RAP1 (UniProtKB/TrEMBL),   A0A8I3N406 (UniProtKB/TrEMBL),   A0A8C0T715 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530844   ⟸   XM_038674916
- Peptide Label: isoform X4
- UniProtKB: A0A8C0RAP1 (UniProtKB/TrEMBL),   A0A8I3N406 (UniProtKB/TrEMBL),   A0A8C0T715 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845008453   ⟸   ENSCAFT00845010832
Ensembl Acc Id: ENSCAFP00845008522   ⟸   ENSCAFT00845010922
Ensembl Acc Id: ENSCAFP00845008565   ⟸   ENSCAFT00845010974
Ensembl Acc Id: ENSCAFP00845008432   ⟸   ENSCAFT00845010804
Protein Domains
BRCT   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014600 Ensembl
  ENSCAFG00845006070 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845010804 ENTREZGENE
  ENSCAFT00845010832 ENTREZGENE
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
  3.40.50.10190 UniProtKB/Swiss-Prot
InterPro BRCA1 UniProtKB/Swiss-Prot
  BRCA1-associated UniProtKB/Swiss-Prot
  BRCA1_serine_dom UniProtKB/Swiss-Prot
  BRCT_dom UniProtKB/Swiss-Prot
  BRCT_dom_sf UniProtKB/Swiss-Prot
  Znf_C3HC4_RING-type UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
KEGG Report cfa:403437 UniProtKB/Swiss-Prot
NCBI Gene BRCA1 ENTREZGENE
PANTHER BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN UniProtKB/Swiss-Prot
  PTHR13763 UniProtKB/Swiss-Prot
Pfam BRCT UniProtKB/Swiss-Prot
  BRCT_assoc UniProtKB/Swiss-Prot
  zf-C3HC4 UniProtKB/Swiss-Prot
PIRSF BRCA1 UniProtKB/Swiss-Prot
PRINTS BRSTCANCERI UniProtKB/Swiss-Prot
PROSITE BRCT UniProtKB/Swiss-Prot
  ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
SMART BRCT UniProtKB/Swiss-Prot
  RING UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF52113 UniProtKB/Swiss-Prot
UniProt A0A0A1G434_CANLF UniProtKB/TrEMBL
  A0A0A1G650_CANLF UniProtKB/TrEMBL
  A0A8C0LXT4_CANLF UniProtKB/TrEMBL
  A0A8C0LXW9_CANLF UniProtKB/TrEMBL
  A0A8C0M0X1_CANLF UniProtKB/TrEMBL
  A0A8C0RAM3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RAP1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T715 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0T776 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MRE9_CANLF UniProtKB/TrEMBL
  A0A8I3MXX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N406 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NDJ5_CANLF UniProtKB/TrEMBL
  A0A8P0SJ84_CANLF UniProtKB/TrEMBL
  BRCA1_CANLF UniProtKB/Swiss-Prot
  Q6YK80_CANLF UniProtKB/TrEMBL
  Q95153 ENTREZGENE
  Q9TU33_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38516 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 BRCA1  BRCA1 DNA repair associated    BRCA1, DNA repair associated  Symbol and/or name change 5135510 APPROVED