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Pathways
Genes search result for Ictidomys tridecemlineatus
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57 records found for search term Tox
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
12587467Toxthymocyte selection associated high mobility group boxENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN lymph node development (ortholog); lymphocyte differentiation (ortholog); Peyer's patch development (ortholog); FOUND IN nucleus (inferred)NW_0049364961384721014146110Squirrel26symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12461344Tox2TOX high mobility group box family member 2ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN female gonad development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); response to gonadotropin (ortholog); FOUND IN nucleoplasm (inferred);NW_00493653026467832774162Squirrel15symbol , old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12579737Tox3TOX high mobility group box family member 3ENCODES a protein that exhibits chromatin binding (inferred); chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN calcium-mediated signaling (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cleft Lip with or witNW_00493647552836155388104Squirrel26symbol , old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12723269Tox4TOX high mobility group box family member 4ENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN positive regulation of transcription elongation by RNA polymerase II (inferred); regulation of transcription by RNA polymerase II (inferred); regulation of transcription elongation by RNA polymeraseNW_004936880628316646006Squirrel21symbol , namegene, protein-coding, MODEL [RefSeq]
12598755LOC101969313TOX high mobility group box family member 4-likeNW_00493658510217741023580Squirrelnamegene, pseudo, MODEL [RefSeq]
12647578Gucy2cguanylate cyclase 2CENCODES a protein that exhibits guanylate cyclase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN regulation of cell population proliferation (ortholog); response to toxic substance (ortholog); ASSOCIATENW_00493658727429112811139Squirrel37old_gene_name , descriptiongene, protein-coding, MODEL [RefSeq]
124923054LOC120885656anthrax toxin receptor-likeSquirrelnamegene, protein-coding, MODEL [RefSeq]
125073373LOC120885724anthrax toxin receptor-likeSquirrelnamegene, protein-coding, MODEL [RefSeq]
124996868LOC120885726anthrax toxin receptor-likeSquirrelnamegene, protein-coding, MODEL [RefSeq]
12552622LOC101967932multidrug and toxin extrusion protein 1ENCODES a protein that exhibits antiporter activity (inferred); L-amino acid transmembrane transporter activity (inferred); L-arginine transmembrane transporter activity (inferred); INVOLVED IN amino acid import across plasma membrane (inferred); L-alpha-amino acid transmembrane transport (inferred)NW_004936881222722260719Squirrel31old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12470337LOC101970809multidrug and toxin extrusion protein 2-likeENCODES a protein that exhibits antiporter activity (inferred); polyspecific organic cation:proton antiporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN organic cation transport (inferred); proton transmembrane transport (inferred); transmembrane transport (inferNW_004936881168930221399Squirrel13namegene, protein-coding, MODEL [RefSeq]
12628210LOC101967586ras-related C3 botulinum toxin substrate 1-likeNW_004936580840194840823Squirrelold_gene_name , namegene, pseudo, MODEL [RefSeq]
12735765Antxr1ANTXR cell adhesion molecule 1ENCODES a protein that exhibits actin filament binding (inferred); collagen binding (inferred); metal ion binding (inferred); INVOLVED IN blood vessel development (ortholog); negative regulation of extracellular matrix assembly (ortholog); positive regulation of metallopeptidase activity (ortholog);NW_0049364911328898613516878Squirrel43old_gene_namegene, protein-coding, MODEL [RefSeq]
12491606Antxr2ANTXR cell adhesion molecule 2ENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN collagen fibril organization (ortholog); single fertilization (ortholog); uterus development (ortholog); ASSOCIATED WITH ankylosing NW_00493674919363072014452Squirrel35old_gene_namegene, protein-coding, MODEL [RefSeq]
13184668LOC110598553ANTXR likeNW_00493655474727407489155Squirrelold_gene_namegene, protein-coding, MODEL [RefSeq]
12587615Rac1Rac family small GTPase 1ENCODES a protein that exhibits ATPase binding (ortholog); GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament organization (ortholog); actin filament polymerization (ortholog); PARTICIPATES IN Arf family mediated signaling pathwNW_004936750107689122679Squirrel305old_gene_namegene, protein-coding, MODEL [RefSeq]
12527617Rac2Rac family small GTPase 2ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); bone resorption (ortholog); cell projection assembly (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Chronic PerioNW_00493649237263753737961Squirrel63old_gene_namegene, protein-coding, MODEL [RefSeq]
12506362Rac3Rac family small GTPase 3ENCODES a protein that exhibits calcium-dependent protein binding (inferred); G protein activity (inferred); GTP binding (inferred); INVOLVED IN cerebral cortex GABAergic interneuron development (ortholog); homeostasis of number of cells within a tissue (ortholog); neuromuscular process (ortholog); NW_00493659455277885530694Squirrel46old_gene_namegene, protein-coding, MODEL [RefSeq]
12572471Tmem181transmembrane protein 181ENCODES a protein that exhibits toxic substance binding (inferred); FOUND IN membrane (inferred)NW_0049364891027573910328102Squirrel4descriptiongene, protein-coding, MODEL [RefSeq]
12606647A4galtalpha 1,4-galactosyltransferase (P1PK blood group)ENCODES a protein that exhibits galactosyltransferase activity (ortholog); lactosylceramide 4-alpha-galactosyltransferase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN globoside biosynthetic process (ortholog); plasma membrane organizationNW_004936718594462630926Squirrel23descriptiongene, protein-coding, MODEL [RefSeq]
12673640Abtb2ankyrin repeat and BTB domain containing 2ENCODES a protein that exhibits protein heterodimerization activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); FOUND IN nucleoplasm (inferred)NW_00493653337059023866998Squirrel4descriptiongene, protein-coding, MODEL [RefSeq]
12552000Aqp10aquaporin 10ENCODES a protein that exhibits channel activity (inferred); glycerol channel activity (inferred); urea transmembrane transporter activity (inferred); INVOLVED IN glycerol transmembrane transport (inferred); protein homotetramerization (inferred); response to toxNW_00493658039812543984895Squirrel25descriptiongene, protein-coding, MODEL [RefSeq]
12549617Arhgap33Rho GTPase activating protein 33ENCODES a protein that exhibits GTPase activator activity (inferred); phosphatidylinositol binding (inferred); protein kinase binding (inferred); INVOLVED IN regulation of dendritic spine morphogenesis (ortholog); response to toxic substance (ortholog); ASSOCIATNW_004936570539839553018Squirrel31descriptiongene, protein-coding, MODEL [RefSeq]
12556627Ass1argininosuccinate synthase 1ENCODES a protein that exhibits argininosuccinate synthase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN acute-phase response (ortholog); argininosuccinate metabolic process (ortholog); cellular response to amine stimulus (ortholog); PARTINW_0049364871748230717527407Squirrel126descriptiongene, protein-coding, MODEL [RefSeq]
12634036Blmhbleomycin hydrolaseENCODES a protein that exhibits aminopeptidase activity (inferred); cysteine-type aminopeptidase activity (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN response to toxic substance (ortholog); response to xenobiotic stimulus (ortholog);NW_00493653862516026298281Squirrel29descriptiongene, protein-coding, MODEL [RefSeq]
12592015Cdh13cadherin 13ENCODES a protein that exhibits adiponectin binding (inferred); beta-catenin binding (inferred); cadherin binding (inferred); INVOLVED IN cellular response to toxic substance (ortholog); cellular response to xenobiotic stimulus (ortholog); ASSOCIATED WITH amphetNW_00493664139251854223421Squirrel84descriptiongene, protein-coding, MODEL [RefSeq]
12732308Crispld2cysteine rich secretory protein LCCL domain containing 2ENCODES a protein that exhibits glycosaminoglycan binding (inferred); heparin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); lung development (ortholog); ASSOCIATED WITH liver disease (ortholog); lung disease (ortholog); toxic enceNW_00493664132287913277379Squirrel12descriptiongene, protein-coding, MODEL [RefSeq]
12723350Gfergrowth factor, augmenter of liver regenerationENCODES a protein that exhibits flavin-dependent sulfhydryl oxidase activity (ortholog); INVOLVED IN cellular response to actinomycin D (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to toxic substance (ortholog); PARTICIPATES NW_00493669420513622053812Squirrel61descriptiongene, protein-coding, MODEL [RefSeq]
12725468Ido1indoleamine 2,3-dioxygenase 1ENCODES a protein that exhibits amino acid binding (ortholog); indoleamine 2,3-dioxygenase activity (ortholog); oxygen binding (ortholog); INVOLVED IN inflammatory response (ortholog); kynurenic acid biosynthetic process (ortholog); L-tryptophan catabolic process to L-kynurenine (ortholog); PARTICIPNW_004936843658058672662Squirrel89descriptiongene, protein-coding, MODEL [RefSeq]
12492532Il20rainterleukin 20 receptor subunit alphaENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); INVOLVED IN cytokine-mediated signaling pathway (ortholog); positive regulation of intrinsic apoptotic signaling pathway (ortholog); regulation of bone resorption (ortholog); ASSOCIATED WITH SpoNW_00493656043841264397971Squirrel12descriptiongene, protein-coding, MODEL [RefSeq]
12610946Il21interleukin 21ENCODES a protein that exhibits cytokine activity (inferred); cytokine receptor binding (inferred); interleukin-2 receptor binding (inferred); INVOLVED IN positive regulation of B cell proliferation (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of iNW_00493666216898791696883Squirrel81descriptiongene, protein-coding, MODEL [RefSeq]
12588208Il23ainterleukin 23 subunit alphaENCODES a protein that exhibits cytokine activity (inferred); interleukin-23 receptor binding (inferred); INVOLVED IN positive regulation of receptor signaling pathway via JAK-STAT (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); T cell proliferation (ortholog); PARTNW_004936646743630745998Squirrel86descriptiongene, protein-coding, MODEL [RefSeq]
12727798Il2rbinterleukin 2 receptor subunit betaENCODES a protein that exhibits interleukin-2 binding (ortholog); interleukin-2 receptor activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling patNW_00493649237959403805822Squirrel53descriptiongene, protein-coding, MODEL [RefSeq]
12607329Kdm5clysine demethylase 5CENCODES a protein that exhibits identical protein binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN gene expression (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); response to toxNW_004936751159628204136Squirrel58descriptiongene, protein-coding, MODEL [RefSeq]
12529384Ldlrlow density lipoprotein receptorENCODES a protein that exhibits low-density lipoprotein particle receptor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN artery development (ortholog); cholesterol homeostasis (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN atherosclerosis pathway; ASSONW_00493665912594051300545Squirrel301descriptiongene, protein-coding, MODEL [RefSeq]
12471977LOC101958062glutathione S-transferase A4ENCODES a protein that exhibits toxic substance binding (ortholog); INVOLVED IN cellular response to lithium ion (ortholog); response to herbicide (ortholog); response to nicotine (ortholog); PARTICIPATES IN glutathione conjugation pathway; ASSOCIATED WITH arterNW_00493647678732187888301Squirrel34descriptiongene, protein-coding, MODEL [RefSeq]
12585153LOC101960208glycine N-acyltransferase-likeENCODES a protein that exhibits acyltransferase activity (inferred); glycine N-acyltransferase activity (inferred); glycine N-benzoyltransferase activity (inferred); INVOLVED IN benzoyl-CoA metabolic process (inferred); glycine metabolic process (inferred); response to toxNW_00493658135725353582325Squirrel20descriptiongene, protein-coding, MODEL [RefSeq]
12735364LOC101968779HLA class II histocompatibility antigen, DQ beta 1 chain-likeENCODES a protein that exhibits protein antigen binding (inferred); toxic substance binding (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN adaptive immune response (inferred); antigen processing and presentation (inferred); antigen processiNW_004936727361446368507Squirrel18descriptiongene, protein-coding, MODEL [RefSeq]
12649012LOC101969732dimethylaniline monooxygenase [N-oxide-forming] 1ENCODES a protein that exhibits flavin adenine dinucleotide binding (inferred); hypotaurine monooxygenase activity (inferred); monooxygenase activity (inferred); INVOLVED IN organic acid metabolic process (inferred); taurine biosynthetic process (inferred); toxiNW_0049364811585755615873883Squirrel18descriptiongene, protein-coding, MODEL [RefSeq]
12721511LOC101974333L-amino-acid oxidase-likeENCODES a protein that exhibits L-amino-acid oxidase activity (inferred); oxidoreductase activity (inferred); toxin activity (inferred); INVOLVED IN amino acid catabolic process (inferred); defense response to bacterium (inferred); modulation of process of anothNW_0049364742438700124392258Squirrel14descriptiongene, protein-coding, MODEL [RefSeq]
12545303Lrp5LDL receptor related protein 5ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); INVOLVED IN amino acid transport (ortholog); anatomical structure regression (ortholog); anterior/posterior pattern specification (ortholog); PARTICIPATES IN altered Wnt signaliNW_00493659917463091814471Squirrel136descriptiongene, protein-coding, MODEL [RefSeq]
12669704Lrp6LDL receptor related protein 6ENCODES a protein that exhibits apolipoprotein binding (ortholog); toxin transmembrane transporter activity (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); axis elongation (ortholog); axis elongation involved in somitogenesis (ortholNW_00493658750652005143029Squirrel206descriptiongene, protein-coding, MODEL [RefSeq]
12521068Nefhneurofilament heavy chainENCODES a protein that exhibits protein-containing complex binding (ortholog); protein-macromolecule adaptor activity (ortholog); toxic substance binding (ortholog); INVOLVED IN axon regeneration (ortholog); cellular response to estradiol stimulus (ortholog); ceNW_00493665734434063453096Squirrel101descriptiongene, protein-coding, MODEL [RefSeq]
12607176Nefmneurofilament medium chainENCODES a protein that exhibits protein-containing complex binding (ortholog); signaling receptor binding (ortholog); toxic substance binding (ortholog); INVOLVED IN axo-dendritic transport (ortholog); axon regeneration (ortholog); cellular response to estradiolNW_00493675716629051668707Squirrel65descriptiongene, protein-coding, MODEL [RefSeq]
12478856Nr4a2nuclear receptor subfamily 4 group A member 2ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN adult locomotory behavior (ortholog); cellular response to oxidative stress (ortholog); centrNW_0049364692191211821920486Squirrel110descriptiongene, protein-coding, MODEL [RefSeq]
12472413P2rx1purinergic receptor P2X 1ENCODES a protein that exhibits ATP binding (ortholog); extracellularly ATP-gated monoatomic cation channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); insemination (ortholog); monoatomic cation transmembrane transport (ortholog); NW_004936677530338546742Squirrel75descriptiongene, protein-coding, MODEL [RefSeq]
12606688Phaxphosphorylated adaptor for RNA exportENCODES a protein that exhibits toxic substance binding (ortholog); INVOLVED IN snRNA export from nucleus (ortholog); ASSOCIATED WITH Hirschsprung's disease (ortholog); FOUND IN neuronal cell body (ortholog)NW_004936504158514592Squirrel18descriptiongene, protein-coding, MODEL [RefSeq]
12466561Ppp1r9aprotein phosphatase 1 regulatory subunit 9AENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic subNW_00493658549815555277185Squirrel71descriptiongene, protein-coding, MODEL [RefSeq]
12690157Ptpn13protein tyrosine phosphatase non-receptor type 13ENCODES a protein that exhibits hydrolase activity (inferred); phosphatidylinositol 3-kinase regulatory subunit binding (inferred); phosphoprotein phosphatase activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); negative regulation oNW_004936920313762510334Squirrel74descriptiongene, protein-coding, MODEL [RefSeq]
12637844Rnase6ribonuclease A family member 6ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); nuclease activity (inferred); INVOLVED IN defense response to virus (ortholog); ASSOCIATED WITH liver disease (ortholog); toxic encephalopathy (ortholog); FOUND IN cNW_0049368807853279342Squirrel26descriptiongene, protein-coding, MODEL [RefSeq]
12632877RorcRAR related orphan receptor CENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); transcription coactivator binding (ortholog); INVOLVED IN adipose tissue development (ortholog); alpha-beta T cell differentiation (ortholog); cell differentiation (ortholog); ASSOCIATEDNW_00493658019976402020649Squirrel81descriptiongene, protein-coding, MODEL [RefSeq]
12440170Slc22a3solute carrier family 22 member 3ENCODES a protein that exhibits dopamine:sodium symporter activity (ortholog); spermidine transmembrane transporter activity (ortholog); toxin transmembrane transporter activity (ortholog); INVOLVED IN dopamine transport (ortholog); histamine transport (orthologNW_0049364891169375511774380Squirrel78descriptiongene, protein-coding, MODEL [RefSeq]
12518597Slc6a14solute carrier family 6 member 14ENCODES a protein that exhibits aromatic amino acid transmembrane transporter activity (ortholog); INVOLVED IN response to toxic substance (ortholog); ASSOCIATED WITH Acidoses (ortholog); celiac disease (ortholog); Experimental Sarcoma (ortholog); FOUND IN brushNW_0049364791302483113051908Squirrel31descriptiongene, protein-coding, MODEL [RefSeq]
12450116Srsf9serine and arginine rich splicing factor 9ENCODES a protein that exhibits mRNA binding (inferred); nucleic acid binding (inferred); protein domain specific binding (inferred); INVOLVED IN response to alkaloid (ortholog); response to toxic substance (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCINW_004936668484922491576Squirrel27descriptiongene, protein-coding, MODEL [RefSeq]
12541052St8sia1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1ENCODES a protein that exhibits sialyltransferase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH liver disease (ortholog); toxic encephalopathy (ortholog); FNW_00493654846712574797917Squirrel18descriptiongene, protein-coding, MODEL [RefSeq]
12663976Sting1stimulator of interferon response cGAMP interactor 1ENCODES a protein that exhibits 2',3'-cyclic GMP-AMP binding (inferred); cyclic-di-GMP binding (inferred); identical protein binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); defense response to virus (ortholog); positive regulation of transcription by RNA polymerase INW_00493653185559668562829Squirrel132descriptiongene, protein-coding, MODEL [RefSeq]
12631110Xrcc1X-ray repair cross complementing 1ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (inferred); ADP-D-ribose modification-dependent protein binding (inferred); damaged DNA binding (inferred); INVOLVED IN base-excision repair (ortholog); DNA damage response (ortholog); DNA repair (orthologNW_004936706752571783746Squirrel201descriptiongene, protein-coding, MODEL [RefSeq]