| 11955338 | EGF | epidermal growth factor | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); INVOLVED IN branching morphogenesis of an epithelial tube (ortholog); epidermal growth factor receptor signaling pathway (ortholog); ERBB2-EGFR signaling pathway (ortholog); PAR TICIPATES IN altered epidermal growth factor/neuregulin signaling pathway; ceramide signaling pathway; E-cadherin signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); adenocarcinoma (ortholog); AIDS-Associated Nephropathy (ortholog); FOUND IN extracellular space (ortholog) | 4 | 102410724 | 102509691 | Bonobo | 155 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 11966703 | EGFL6 | EGF like domain multiple 6 | ENCODES a protein that exhibits calcium ion binding (inferred); integrin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); FOUND I N basement membrane (ortholog); extracellular matrix (ortholog) | X | 6177141 | 6240969 | Bonobo | 12 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12045710 | EGFL7 | EGF like domain multiple 7 | ENCODES a protein that exhibits Notch binding (ortholog); INVOLVED IN blood vessel development (ortholog); negative regulation of cell migration (ortholog); negative regulation of Notch signaling pathway (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); FOUND IN e xtracellular space (ortholog) | 9 | 107735192 | 107748729 | Bonobo | 18 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11900369 | EGFL8 | EGF like domain multiple 8 | ENCODES a protein that exhibits calcium ion binding (inferred); signaling receptor binding (inferred); INVOLVED IN in utero embryonic development (ortholog); FOUND IN cell surface (inferred); extracellular region (inferred) | 6 | 31811944 | 31815796 | Bonobo | 7 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11946476 | MEGF8 | multiple EGF like domains 8 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN aorta development (ortholog); coronary vasculature development (ortholog); determination of digestive tract left/right asymmetry (ortholog); ASSOCIATED WITH Carpenter syndrome (ortholog); Carpenter syndrome 2 (ortholog); cra niosynostosis (ortholog); FOUND IN ubiquitin ligase complex (ortholog) | 19 | 39213339 | 39265391 | Bonobo | 54 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12004336 | MEGF9 | multiple EGF like domains 9 | ENCODES a protein that exhibits extracellular matrix structural constituent (inferred); INVOLVED IN animal organ morphogenesis (inferred); axon guidance (inferred); blood vessel morphogenesis (inferred); FOUND IN basement membrane (inferred); membrane (inferred) | 9 | 91728219 | 91842056 | Bonobo | 9 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11674886 | MEGF10 | multiple EGF like domains 10 | ENCODES a protein that exhibits complement component C1q complex binding (inferred); Notch binding (inferred); scavenger receptor activity (inferred); INVOLVED IN apoptotic process involved in development (ortholog); engulfment of apoptotic cell (ortholog); recognition of apoptotic cell (ortholog); ASSOCIATED WITH congenital myopathy 10B (ortholog); Deglutition Disorders (ortholog); early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome (ortholog); FOUND IN membrane (inferred); phagocytic cup (inferred); plasma membrane (inferred) | 5 | 122639155 | 122877324 | Bonobo | 42 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11718077 | MEGF11 | multiple EGF like domains 11 | INVOLVED IN homotypic cell-cell adhesion (inferred); retina layer formation (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 15 | 44836750 | 45208674 | Bonobo | 5 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11813099 | CRIPTO | cripto, EGF-CFC family member | ENCODES a protein that exhibits coreceptor activity (ortholog); nodal binding (ortholog); type I activin receptor binding (ortholog); INVOLVED IN anterior/posterior axis specification (ortholog); anterior/posterior axis specification, embryo (ortholog); cardiac muscle cell differentiation (ortholog) ; PARTICIPATES IN glypican signaling pathway; ASSOCIATED WITH colon cancer (ortholog); congenital heart disease (ortholog); Forebrain Defects (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); Golgi apparatus (ortholog) | 3 | 46473282 | 46478454 | Bonobo | 66 | name | gene, protein-coding, MODEL [RefSeq] |
| 11700362 | CRIPTO3 | cripto, EGF-CFC family member 3 | ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN signal transduction (inferred); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN plasma membrane (inferred) | X | 99628286 | 99629441 | Bonobo | 5 | name | gene, protein-coding, MODEL [RefSeq] |
| 11840542 | EDIL3 | EGF like and discoidin domains 3 | ENCODES a protein that exhibits calcium ion binding (inferred); signaling receptor activity (inferred); INVOLVED IN positive regulation of cell-substrate adhesion (ortholog); ASSOCIATED WITH osteoarthritis (ortholog); FOUND IN extracellular region (inferred); plasma membrane (inferred) | 5 | 30895036 | 31337176 | Bonobo | 7 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11869123 | CFC1B | cryptic, EGF-CFC family member 1B | ENCODES a protein that exhibits activin receptor binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); atrial septum morphogenesis (ortholog); coronary vasculature development (ortholog); ASSOCIATED WITH dextro-looped transposition of the great arteries (ortholog); dou ble outlet right ventricle (ortholog); right atrial isomerism (ortholog) | 2B | 29354004 | 29362161 | Bonobo | 26 | name | gene, protein-coding, MODEL [RefSeq] |
| 11707592 | SNED1 | sushi, nidogen and EGF like domains 1 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cell-matrix adhesion (inferred); FOUND IN extracellular matrix (inferred) | 2B | 128253888 | 128351819 | Bonobo | 4 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11898051 | DNER | delta/notch like EGF repeat containing | ENCODES a protein that exhibits calcium ion binding (inferred); Notch binding (inferred); INVOLVED IN glial cell differentiation (ortholog); Notch receptor processing (ortholog); skeletal muscle fiber development (ortholog); PARTICIPATES IN Notch signaling pathway; FOUND IN dendrite (inferred); earl y endosome (inferred); neuronal cell body (inferred) | 2B | 116604193 | 116963026 | Bonobo | 18 | name | gene, protein-coding, MODEL [RefSeq] |
| 11732924 | HBEGF | heparin binding EGF like growth factor | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); growth factor activity (ortholog); INVOLVED IN epidermal growth factor receptor signaling pathway (ortholog); negative regulation of glycoprotein biosynthetic process (ortholog); positive regulation of cell growth ( ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Animal Disease Models (ortholog); Cardiotoxicity (ortholog); FOUND IN extracellular space (ortholog) | 5 | 135699553 | 135713366 | Bonobo | 65 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12023740 | VWCE | von Willebrand factor C and EGF domains | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cellular response to virus (inferred); ASSOCIATED WITH Dwarfism (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); extracellular region (inferred) | 11 | 56557167 | 56596311 | Bonobo | 11 | name | gene, protein-coding, MODEL [RefSeq] |
| 11977960 | VWDE | von Willebrand factor D and EGF domains | ASSOCIATED WITH optic atrophy 12 (ortholog) | 7 | 13028161 | 13106766 | Bonobo | 1 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11698710 | CCBE1 | collagen and calcium binding EGF domains 1 | ENCODES a protein that exhibits calcium ion binding (inferred); collagen binding (inferred); protease binding (inferred); INVOLVED IN lung development (ortholog); lymph vessel development (ortholog); lymphangiogenesis (ortholog); ASSOCIATED WITH Distal Renal Tubular Acidosis 4 with Hemolytic Anemia (ortholog); Facies (ortholog); genetic disease (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred) | 18 | 52819591 | 53087772 | Bonobo | 29 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11940008 | CELSR1 | cadherin EGF LAG seven-pass G-type receptor 1 | ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN anterior/posterior pattern specification (ortholog); apical protein localization (ortholog); establishment of body hair pl anar orientation (ortholog); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); long QT syndrome (ortholog); Lymphatic Malformation 9 (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Bonobo | 50 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12007085 | CELSR2 | cadherin EGF LAG seven-pass G-type receptor 2 | ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN cerebrospinal fluid secretion (ortholog); cilium assembly (ortholog); cilium movement (ortholog); ASSOCIATED WITH coronary artery disease (ortholog); Developmental Disabilities (ortholog); endometrial hyperplasia (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred) | 1 | 111627551 | 111653775 | Bonobo | 46 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11997142 | CELSR3 | cadherin EGF LAG seven-pass G-type receptor 3 | ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN axonal fasciculation (ortholog); cilium assembly (ortholog); dopaminergic neuron axon guidance (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); CAKUT1 (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog); presynaptic active zone membrane (ortholog) | 3 | 48557976 | 48586051 | Bonobo | 35 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11966453 | HEG1 | heart development protein with EGF like domains 1 | ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN cardiac atrium morphogenesis (ortholog); cardiac muscle tissue growth (ortholog); cell-cell junction organization (ortholog); FOUND IN anchoring junction (inferred); cell surface (inferred); cell-cell junction (inferred) | 3 | 122091832 | 122204436 | Bonobo | 41 | name | gene, protein-coding, MODEL [RefSeq] |
| 329344952 | LOC129395024 | cadherin EGF LAG seven-pass G-type receptor 1-like | | | | | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 11670475 | EGFLAM | EGF like, fibronectin type III and laminin G domains | ENCODES a protein that exhibits calcium ion binding (inferred); glycosaminoglycan binding (inferred); molecular adaptor activity (inferred); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); ASSOCIATED WITH High Myopia (ortholog); FO UND IN cell surface (ortholog); photoreceptor ribbon synapse (ortholog) | 5 | 71909106 | 72119958 | Bonobo | 21 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11983897 | EFEMP1 | EGF containing fibulin extracellular matrix protein 1 | ENCODES a protein that exhibits calcium ion binding (inferred); epidermal growth factor receptor activity (inferred); epidermal growth factor receptor binding (inferred); INVOLVED IN negative regulation of neuron projection development (ortholog); peptidyl-tyrosine phosphorylation (ortholog); positi ve regulation of cell population proliferation (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); adenoma (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN basement membrane (ortholog) | 2A | 56017678 | 56076059 | Bonobo | 70 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11912843 | EFEMP2 | EGF containing fibulin extracellular matrix protein 2 | ENCODES a protein that exhibits calcium ion binding (inferred); heparin binding (inferred); protein homodimerization activity (inferred); INVOLVED IN artery development (ortholog); elastic fiber assembly (ortholog); ASSOCIATED WITH aortic aneurysm (ortholog); aortic disease (ortholog); aortic dissec tion (ortholog); FOUND IN basement membrane (inferred); elastic fiber (inferred); extracellular matrix (inferred) | 11 | 61226755 | 61233181 | Bonobo | 64 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11872471 | MFGE8 | milk fat globule EGF and factor V/VIII domain containing | ENCODES a protein that exhibits phosphatidylethanolamine binding (ortholog); INVOLVED IN phagocytosis, engulfment (ortholog); phagocytosis, recognition (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); colorectal cancer (ortholo g); Experimental Diabetes Mellitus (ortholog); FOUND IN endomembrane system (inferred); external side of plasma membrane (inferred); extracellular region (inferred) | 15 | 67587360 | 67602029 | Bonobo | 21 | name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 11916365 | SCUBE1 | signal peptide, CUB domain and EGF like domain containing 1 | ENCODES a protein that exhibits calcium ion binding (inferred); identical protein binding (inferred); INVOLVED IN positive regulation of smoothened signaling pathway (ortholog); FOUND IN cell surface (inferred); external side of plasma membrane (inferred); extracellular region (inferred) | 22 | 24080438 | 24228401 | Bonobo | 14 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11680918 | SCUBE2 | signal peptide, CUB domain and EGF like domain containing 2 | ENCODES a protein that exhibits hedgehog family protein binding (ortholog); INVOLVED IN chondrocyte differentiation involved in endochondral bone morphogenesis (ortholog); positive regulation of chondrocyte proliferation (ortholog); positive regulation of ossification (ortholog); FOUND IN cell surfa ce (inferred); extracellular region (inferred); extracellular space (inferred) | 11 | 9146533 | 9219816 | Bonobo | 18 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12009395 | SCUBE3 | signal peptide, CUB domain and EGF like domain containing 3 | ENCODES a protein that exhibits BMP binding (inferred); BMP receptor binding (inferred); calcium ion binding (inferred); INVOLVED IN positive regulation of smoothened signaling pathway (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN cell surface (inferred); extracellular region (inferred); extracellular space (inferred) | 6 | 34776605 | 34815808 | Bonobo | 25 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11691591 | EOGT | EGF domain specific O-linked N-acetylglucosamine transferase | ENCODES a protein that exhibits glycosyltransferase activity (inferred); protein O-acetylglucosaminyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN protein O-linked glycosylation (inferred); ASSOCIATED WITH Adams-Oliver syndrome (ortholog); Adams-Oliver Syndrome 4 (ort holog); Desbuquois dysplasia (ortholog); FOUND IN endoplasmic reticulum lumen (inferred) | 3 | 68910100 | 68950816 | Bonobo | 15 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11685119 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN blood vessel development (ortholog); in utero embryonic development (ortholog); lymphatic endothelial cell differentiation (ortholog); ASSOCIATED WITH Lymphatic Malformation 11 (ortholog); FOUND IN plasma membrane (inferred); receptor complex (inferred) | 1 | 42602333 | 42624471 | Bonobo | 39 | name | gene, protein-coding, MODEL [RefSeq] |
| 11801628 | TMEFF1 | transmembrane protein with EGF like and two follistatin like domains 1 | ENCODES a protein that exhibits receptor ligand inhibitor activity (ortholog); INVOLVED IN host-mediated suppression of symbiont invasion (inferred); FOUND IN plasma membrane (ortholog) | 9 | 71681899 | 71788447 | Bonobo | 5 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11791908 | TMEFF2 | transmembrane protein with EGF like and two follistatin like domains 2 | INVOLVED IN negative regulation of cell migration (ortholog); negative regulation of integrin biosynthetic process (ortholog); negative regulation of stress fiber assembly (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); polycystic ovary syndrome (ortholog); prostate cancer (ortholog); FOUND IN membrane (inferred) | 2B | 79242825 | 79489113 | Bonobo | 16 | name | gene, protein-coding, MODEL [RefSeq] |
| 11856737 | SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | ENCODES a protein that exhibits calcium ion binding (inferred); chromatin binding (inferred); integrin binding (inferred); INVOLVED IN epidermis development (ortholog); gene expression (ortholog); lymph circulation (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); extracell ular space (inferred) | 9 | 81521495 | 81727869 | Bonobo | 33 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12016321 | LOC100975124 | multiple epidermal growth factor-like domains protein 6 | | 1 | 2155295 | 2283034 | Bonobo | 1 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11688247 | CRELD1 | CRELD disulfide isomerase 1 | ASSOCIATED WITH Atrioventricular Septal Defect 2 (ortholog); Congenital Heart Defects, Multiple Types, 4 (ortholog); congenital heart disease (ortholog); FOUND IN glutamatergic synapse (ortholog); synapse (ortholog) | 3 | 9878265 | 9889826 | Bonobo | 15 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11898067 | CRELD2 | CRELD disulfide isomerase 2 | ENCODES a protein that exhibits calcium ion binding (inferred); isomerase activity (inferred); protein disulfide isomerase activity (inferred); FOUND IN endoplasmic reticulum (inferred); extracellular space (inferred); Golgi apparatus (inferred) | 22 | 30139539 | 30152462 | Bonobo | 10 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11982824 | ADGRL4 | adhesion G protein-coupled receptor L4 | ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN protein-containing complex assembly (ortholog); ASSOCIATED WITH glioblastoma (ortholog); hypertrophic cardiomyopathy (orth olog); Left Ventricular Hypertrophy (ortholog); FOUND IN cytoplasmic vesicle (ortholog) | 1 | 78099504 | 78216060 | Bonobo | 22 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11712691 | ADGRE1 | adhesion G protein-coupled receptor E1 | ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); cellular response to tumor necrosis factor (orth olog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cell periphery (ortholog); external side of plasma membrane (ortholog) | 19 | 5918097 | 5970069 | Bonobo | 21 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11949673 | ADGRE3 | adhesion G protein-coupled receptor E3 | ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (inferred); cell surface receptor signaling path way (inferred); G protein-coupled receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); ruffle membrane (inferred) | 19 | 14163207 | 14225794 | Bonobo | 16 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11786721 | LOC100974936 | adhesion G protein-coupled receptor E2 | ENCODES a protein that exhibits calcium ion binding (inferred); chondroitin sulfate binding (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (inferred); cell adhesion (inferred); cell migration (inferred ); ASSOCIATED WITH dermatographia (ortholog); vibratory urticaria (ortholog); FOUND IN leading edge membrane (inferred); membrane (inferred); plasma membrane (inferred) | 19 | 14259830 | 14331832 | Bonobo | 26 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11823987 | LOC100967790 | putative adhesion G protein-coupled receptor E4P | ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (inferred); cell surface receptor signaling path way (inferred); G protein-coupled receptor signaling pathway (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 19 | 5982040 | 6026565 | Bonobo | 14 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11704382 | EGFR | epidermal growth factor receptor | ENCODES a protein that exhibits calmodulin binding (ortholog); epidermal growth factor binding (ortholog); epidermal growth factor receptor activity (ortholog); INVOLVED IN astrocyte activation (ortholog); cell morphogenesis (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATE S IN altered epidermal growth factor/neuregulin signaling pathway; cetuximab pharmacodynamics pathway; E-cadherin signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); adenocarcinoma (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); cell surface (ortholog) | 7 | 55614042 | 55807285 | Bonobo | 526 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11677418 | NELL1 | neural EGFL like 1 | ENCODES a protein that exhibits heparin binding (ortholog); identical protein binding (ortholog); protein kinase C binding (ortholog); INVOLVED IN positive regulation of apoptotic process (ortholog); positive regulation of ossification (ortholog); regulation of osteoblast differentiation (ortholog); ASSOCIATED WITH craniosynostosis (ortholog); esophagus adenocarcinoma (ortholog); prostate cancer (ortholog); FOUND IN extracellular space (ortholog) | 11 | 20697153 | 21600601 | Bonobo | 36 | name | gene, protein-coding, MODEL [RefSeq] |
| 11963866 | NELL2 | neural EGFL like 2 | ENCODES a protein that exhibits heparin binding (ortholog); identical protein binding (ortholog); protein kinase C binding (ortholog); INVOLVED IN development of secondary female sexual characteristics (ortholog); neurogenesis (ortholog); neuron cellular homeostasis (ortholog); ASSOCIATED WITH lung adenocarcinoma (ortholog); FOUND IN dendrite (ortholog); extracellular space (ortholog); perikaryon (ortholog) | 12 | 43820215 | 44226249 | Bonobo | 29 | name | gene, protein-coding, MODEL [RefSeq] |
| 11784910 | EPS8 | EGFR pathway substrate 8, signaling adaptor | ENCODES a protein that exhibits actin binding (inferred); small GTPase binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament bundle assembly (ortholog); adult locomotory behavior (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCI ATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 102 (ortholog); autosomal recessive nonsyndromic deafness 106 (ortholog); FOUND IN postsynaptic density (ortholog) | 12 | 15617536 | 15788537 | Bonobo | 77 | name | gene, protein-coding, MODEL [RefSeq] |
| 11962137 | EREG | epiregulin | ENCODES a protein that exhibits growth factor activity (ortholog); INVOLVED IN epidermal growth factor receptor signaling pathway (ortholog); ERBB2-EGFR signaling pathway (ortholog); ERBB2-ERBB4 signaling pathway (ortholog); PARTICIPATES IN epidermal growth fact or/neuregulin signaling pathway; ASSOCIATED WITH cholesteatoma (ortholog); erythropoietic protoporphyria (ortholog); Experimental Colitis (ortholog); FOUND IN extracellular space (ortholog) | 4 | 49806505 | 49827961 | Bonobo | 74 | description | gene, protein-coding, MODEL [RefSeq] |
| 11873345 | SHC1 | SHC adaptor protein 1 | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); identical protein binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); angiogenesis (ortholog); animal organ regeneration (ortholog); PARTICIPATES IN brain-d erived neurotrophic factor signaling pathway; epidermal growth factor/neuregulin signaling pathway; erythropoietin signaling pathway; ASSOCIATED WITH Albuminuria (ortholog); Alzheimer's disease (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); FOUND IN endosome membrane (ortholog); Shc-EGFR complex (ortholog) | 1 | 130310778 | 130323001 | Bonobo | 152 | description | gene, protein-coding, MODEL [RefSeq] |
| 11826938 | TGFA | transforming growth factor alpha | ENCODES a protein that exhibits epidermal growth factor receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); epidermal growth factor receptor signaling pathway (ortholog); ERBB2-EGFR signaling pathway (ortholog); PARTICIPATES IN altered epidermal gr owth factor/neuregulin signaling pathway; epidermal growth factor/neuregulin signaling pathway; pancreatic cancer pathway; ASSOCIATED WITH acute kidney failure (ortholog); Animal Mammary Neoplasms (ortholog); Experimental Liver Neoplasms (ortholog); FOUND IN extracellular space (ortholog) | 2A | 70510727 | 70617628 | Bonobo | 84 | description | gene, protein-coding, MODEL [RefSeq] |