CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3) - Rat Genome Database

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Gene: CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3) Pan paniscus
Analyze
Symbol: CELSR3
Name: cadherin EGF LAG seven-pass G-type receptor 3
RGD ID: 11997142
Description: ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN axonal fasciculation (ortholog); cilium assembly (ortholog); dopaminergic neuron axon guidance (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 1 (ortholog); autism spectrum disorder (ortholog); CAKUT1 (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog); presynaptic active zone membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,610,805 - 48,639,012 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,615,573 - 48,643,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,557,976 - 48,586,051 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,639,936 - 49,667,335 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,639,942 - 49,667,335 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
CELSR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,610,805 - 48,639,012 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,615,573 - 48,643,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,557,976 - 48,586,051 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,639,936 - 49,667,335 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,639,942 - 49,667,335 (-)Ensemblpanpan1.1panPan2
CELSR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,636,463 - 48,662,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,636,463 - 48,662,886 (-)EnsemblGRCh38hg38GRCh38
GRCh37348,673,896 - 48,700,319 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,648,900 - 48,675,352 (-)NCBINCBI36Build 36hg18NCBI36
Build 34348,648,900 - 48,675,352NCBI
Celera348,629,806 - 48,656,257 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,732,066 - 48,758,302 (-)NCBIHuRef
CHM1_1348,626,190 - 48,652,451 (-)NCBICHM1_1
T2T-CHM13v2.0348,665,423 - 48,691,846 (-)NCBIT2T-CHM13v2.0
Celsr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,703,244 - 108,730,168 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,703,519 - 108,730,168 (+)EnsemblGRCm39 Ensembl
GRCm389108,826,023 - 108,852,969 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,826,320 - 108,852,969 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,728,651 - 108,755,300 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369108,683,543 - 108,710,186 (+)NCBIMGSCv36mm8
Celera9108,433,487 - 108,460,140 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.63NCBI
Celsr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,409,136 - 118,438,593 (+)NCBIGRCr8
mRatBN7.28109,530,597 - 109,558,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,530,641 - 109,558,354 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,148,091 - 115,175,780 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,347,270 - 113,374,959 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,190,068 - 111,217,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,620,293 - 117,648,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,620,317 - 117,648,028 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,964,621 - 116,991,771 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,882,883 - 113,923,950 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,902,337 - 113,943,405 (+)NCBI
Celera8108,824,695 - 108,852,099 (+)NCBICelera
Cytogenetic Map8q32NCBI
Celsr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532725,243 - 749,173 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955532724,306 - 749,192 (-)NCBIChiLan1.0ChiLan1.0
CELSR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,457,430 - 40,495,128 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,457,657 - 40,483,881 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2040,375,514 - 40,412,346 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02040,943,952 - 40,980,477 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,970,510 - 40,980,478 (+)EnsemblROS_Cfam_1.0 Ensembl
ROS_Cfam_1.0 Ensembl2040,943,706 - 40,966,371 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,181,313 - 40,217,932 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,585,605 - 40,622,438 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,867,118 - 40,903,641 (+)NCBIUU_Cfam_GSD_1.0
Celsr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,676,979 - 63,703,515 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529437,418 - 464,017 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936529437,476 - 464,012 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CELSR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,331,574 - 31,357,469 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,331,563 - 31,357,374 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,595,206 - 34,637,678 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CELSR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,046,361 - 10,073,689 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,045,900 - 10,072,395 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041157,017,459 - 157,043,000 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Celsr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,651,756 - 2,675,923 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247302,650,096 - 2,675,930 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000038881   ⟹   ENSPPAP00000016188
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl349,639,942 - 49,667,335 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000038898   ⟹   ENSPPAP00000016204
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl349,641,680 - 49,665,723 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000038909   ⟹   ENSPPAP00000016215
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl349,641,680 - 49,665,723 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000038914   ⟹   ENSPPAP00000016220
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl349,641,680 - 49,665,723 (-)Ensembl
RefSeq Acc Id: XM_003818392   ⟹   XP_003818440
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2248,610,805 - 48,639,012 (-)NCBI
NHGRI_mPanPan1348,615,573 - 48,643,236 (-)NCBI
Mhudiblu_PPA_v0348,557,976 - 48,586,051 (-)NCBI
PanPan1.1349,639,936 - 49,667,335 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008971704   ⟹   XP_008969952
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2248,610,805 - 48,637,364 (-)NCBI
NHGRI_mPanPan1348,615,573 - 48,642,132 (-)NCBI
Mhudiblu_PPA_v0348,557,976 - 48,584,133 (-)NCBI
PanPan1.1349,639,936 - 49,665,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024928056   ⟹   XP_024783824
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2248,610,805 - 48,637,364 (-)NCBI
NHGRI_mPanPan1348,615,573 - 48,642,132 (-)NCBI
Mhudiblu_PPA_v0348,557,976 - 48,584,133 (-)NCBI
PanPan1.1349,639,936 - 49,665,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034956377   ⟹   XP_034812268
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2248,610,805 - 48,637,364 (-)NCBI
NHGRI_mPanPan1348,615,573 - 48,642,132 (-)NCBI
Mhudiblu_PPA_v0348,557,976 - 48,584,133 (-)NCBI
RefSeq Acc Id: XM_055109883   ⟹   XP_054965858
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2248,616,395 - 48,637,364 (-)NCBI
NHGRI_mPanPan1348,621,154 - 48,642,132 (-)NCBI
RefSeq Acc Id: XR_004670554
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2248,617,412 - 48,637,364 (-)NCBI
NHGRI_mPanPan1348,622,180 - 48,642,132 (-)NCBI
Mhudiblu_PPA_v0348,564,583 - 48,584,133 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003818440   ⟸   XM_003818392
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AGS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008969952   ⟸   XM_008971704
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AGS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024783824   ⟸   XM_024928056
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AGS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034812268   ⟸   XM_034956377
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AGS8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000016204   ⟸   ENSPPAT00000038898
RefSeq Acc Id: ENSPPAP00000016188   ⟸   ENSPPAT00000038881
RefSeq Acc Id: ENSPPAP00000016220   ⟸   ENSPPAT00000038914
RefSeq Acc Id: ENSPPAP00000016215   ⟸   ENSPPAT00000038909
RefSeq Acc Id: XP_054965858   ⟸   XM_055109883
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AGS8 (UniProtKB/TrEMBL)
Protein Domains
Cadherin   EGF-like   G-protein coupled receptors family 2 profile   Laminin EGF-like   Laminin G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031153 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038881.1 UniProtKB/TrEMBL
  ENSPPAT00000038898.1 UniProtKB/TrEMBL
  ENSPPAT00000038909.1 UniProtKB/TrEMBL
  ENSPPAT00000038914.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.220.50 UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
NCBI Gene CELSR3 ENTREZGENE
PANTHER CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 3 UniProtKB/TrEMBL
  FAT ATYPICAL CADHERIN-RELATED UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  Cadherin UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  GAIN UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HormR UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  SM00112 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF49313 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A2R9AGS8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AKP8_PANPA UniProtKB/TrEMBL
  A0A2R9AKQ3_PANPA UniProtKB/TrEMBL
  A0A2R9AML0_PANPA UniProtKB/TrEMBL