ADGRL4 (adhesion G protein-coupled receptor L4) - Rat Genome Database

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Gene: ADGRL4 (adhesion G protein-coupled receptor L4) Pan paniscus
Analyze
Symbol: ADGRL4
Name: adhesion G protein-coupled receptor L4
RGD ID: 11982824
Description: ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN protein-containing complex assembly (ortholog); ASSOCIATED WITH genetic disease (ortholog); glioblastoma (ortholog); hypertrophic cardiomyopathy (ortholog); FOUND IN cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EGF, latrophilin and seven transmembrane domain containing 1; ELTD1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21147,892,334 - 148,008,807 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11147,048,791 - 147,165,268 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0178,099,504 - 78,216,060 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1180,236,721 - 80,353,157 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl180,236,040 - 80,353,157 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADGRL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21147,892,334 - 148,008,807 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11147,048,791 - 147,165,268 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0178,099,504 - 78,216,060 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1180,236,721 - 80,353,157 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl180,236,040 - 80,353,157 (-)Ensemblpanpan1.1panPan2
ADGRL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,889,764 - 79,006,730 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,889,764 - 79,282,124 (-)EnsemblGRCh38hg38GRCh38
GRCh37179,355,449 - 79,472,415 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36179,128,037 - 79,245,083 (-)NCBINCBI36Build 36hg18NCBI36
Celera177,595,032 - 77,712,073 (-)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef177,487,868 - 77,604,946 (-)NCBIHuRef
CHM1_1179,471,875 - 79,588,556 (-)NCBICHM1_1
T2T-CHM13v2.0178,728,626 - 78,845,196 (-)NCBIT2T-CHM13v2.0
Adgrl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393151,143,519 - 151,250,718 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3151,143,524 - 151,250,723 (+)EnsemblGRCm39 Ensembl
GRCm383151,437,882 - 151,545,081 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3151,437,887 - 151,545,086 (+)EnsemblGRCm38mm10GRCm38
MGSCv373151,100,846 - 151,208,045 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363151,375,268 - 151,482,467 (+)NCBIMGSCv36mm8
Celera3157,902,449 - 158,009,462 (+)NCBICelera
Cytogenetic Map3H3NCBI
cM Map376.76NCBI
Adgrl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82243,014,927 - 243,117,226 (+)NCBIGRCr8
mRatBN7.22240,354,909 - 240,457,231 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2240,354,941 - 240,457,225 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2248,150,182 - 248,254,960 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02246,037,208 - 246,141,984 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02240,908,297 - 241,010,524 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02256,609,787 - 256,724,642 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2256,609,787 - 256,724,641 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02275,293,988 - 275,408,900 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42249,764,600 - 249,866,831 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12249,779,206 - 249,881,437 (+)NCBI
Celera2232,295,578 - 232,396,733 (+)NCBICelera
Cytogenetic Map2q45NCBI
Adgrl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542314,395,558 - 14,487,856 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542314,395,712 - 14,487,803 (+)NCBIChiLan1.0ChiLan1.0
ADGRL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1668,078,481 - 68,189,422 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl668,078,246 - 68,220,743 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha670,736,971 - 70,847,924 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0668,665,910 - 68,775,602 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl668,665,865 - 68,803,027 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1668,170,982 - 68,281,896 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0668,116,156 - 68,227,448 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0668,602,665 - 68,712,408 (+)NCBIUU_Cfam_GSD_1.0
Adgrl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505890,076,709 - 90,181,473 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365715,587,059 - 5,691,670 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365715,587,077 - 5,691,623 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6134,362,901 - 134,462,694 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16134,362,714 - 134,462,697 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26124,520,112 - 124,620,447 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12054,208,073 - 54,325,120 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2054,208,321 - 54,327,545 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603363,213,110 - 63,333,108 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgrl4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474218,306,871 - 18,396,342 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474218,306,809 - 18,397,683 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003817342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000066125   ⟹   ENSPPAP00000043190
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl180,236,040 - 80,352,997 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000066126   ⟹   ENSPPAP00000043191
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl180,236,732 - 80,353,157 (-)Ensembl
RefSeq Acc Id: XM_003817342   ⟹   XP_003817390
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21147,892,334 - 148,008,807 (+)NCBI
NHGRI_mPanPan11147,048,791 - 147,165,268 (+)NCBI
Mhudiblu_PPA_v0178,099,504 - 78,216,060 (-)NCBI
PanPan1.1180,236,721 - 80,353,157 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003817390 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000043190.1
  ENSPPAP00000043191.1
Reference Protein Sequences
RefSeq Acc Id: XP_003817390   ⟸   XM_003817342
- Sequence:
RefSeq Acc Id: ENSPPAP00000043190   ⟸   ENSPPAT00000066125
RefSeq Acc Id: ENSPPAP00000043191   ⟸   ENSPPAT00000066126
Protein Domains
EGF-like   G-protein coupled receptors family 2 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000044128 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000066125.1 UniProtKB/TrEMBL
  ENSPPAT00000066126.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.220.50 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
KEGG Report pps:100970438 UniProtKB/TrEMBL
NCBI Gene ADGRL4 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR L4 UniProtKB/TrEMBL
  ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  GAIN UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
PRINTS GPCRSECRETIN UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
UniProt A0A2R9CMG8_PANPA UniProtKB/TrEMBL
  A0A2R9CMJ5_PANPA UniProtKB/TrEMBL