LOC100974936 (adhesion G protein-coupled receptor E2) - Rat Genome Database

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Gene: LOC100974936 (adhesion G protein-coupled receptor E2) Pan paniscus
Analyze
Symbol: LOC100974936 (Ensembl: ADGRE2)
Name: adhesion G protein-coupled receptor E2
RGD ID: 11786721
Description: ENCODES a protein that exhibits calcium ion binding (inferred); chondroitin sulfate binding (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (inferred); cell adhesion (inferred); cell migration (inferred); ASSOCIATED WITH dermatographia (ortholog); genetic disease (ortholog); vibratory urticaria (ortholog); FOUND IN leading edge membrane (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADGRE2; egf-like module containing, mucin-like, hormone receptor-like 2; EMR2
RGD Orthologs
Human
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,655,556 - 19,698,249 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,672,521 - 18,715,225 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,259,830 - 14,331,832 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,155,572 - 15,186,527 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,148,143 - 15,186,458 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100974936
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,655,556 - 19,698,249 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,672,521 - 18,715,225 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,259,830 - 14,331,832 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,155,572 - 15,186,527 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,148,143 - 15,186,458 (-)Ensemblpanpan1.1panPan2
ADGRE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,724,171 - 14,778,560 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1914,732,392 - 14,778,560 (-)EnsemblGRCh38hg38GRCh38
GRCh371914,843,204 - 14,889,372 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,704,205 - 14,750,353 (-)NCBINCBI36Build 36hg18NCBI36
Build 341914,704,204 - 14,750,353NCBI
Celera1914,737,217 - 14,785,126 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,409,913 - 14,457,402 (-)NCBIHuRef
CHM1_11914,843,056 - 14,888,765 (-)NCBICHM1_1
T2T-CHM13v2.01914,850,478 - 14,906,112 (-)NCBIT2T-CHM13v2.0
ADGRE2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12047,929,357 - 47,968,525 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2047,873,897 - 47,968,525 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2047,806,972 - 47,845,107 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02048,443,417 - 48,483,661 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2048,388,495 - 48,483,630 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12047,659,307 - 47,697,828 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02048,085,283 - 48,123,790 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02048,329,358 - 48,368,591 (-)NCBIUU_Cfam_GSD_1.0
LOC100516957
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1263,853,304 - 63,900,460 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2264,549,001 - 64,553,222 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRE2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,402,365 - 13,431,418 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,402,722 - 13,433,848 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660746,161,733 - 6,203,575 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000065860   ⟹   ENSPPAP00000042927
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,148,143 - 15,186,458 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065862   ⟹   ENSPPAP00000042929
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,148,143 - 15,186,458 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065863   ⟹   ENSPPAP00000042930
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,148,143 - 15,186,458 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065864   ⟹   ENSPPAP00000042931
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,148,143 - 15,186,458 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065865   ⟹   ENSPPAP00000042932
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,148,143 - 15,186,458 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000065866   ⟹   ENSPPAP00000042933
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,154,350 - 15,186,458 (-)Ensembl
RefSeq Acc Id: XM_055104361   ⟹   XP_054960336
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,655,566 - 19,698,249 (-)NCBI
NHGRI_mPanPan11918,672,529 - 18,715,225 (-)NCBI
RefSeq Acc Id: XM_055104362   ⟹   XP_054960337
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,655,559 - 19,695,066 (-)NCBI
NHGRI_mPanPan11918,672,524 - 18,712,035 (-)NCBI
RefSeq Acc Id: XM_055104363   ⟹   XP_054960338
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,655,556 - 19,689,517 (-)NCBI
NHGRI_mPanPan11918,672,521 - 18,706,475 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000042927   ⟸   ENSPPAT00000065860
RefSeq Acc Id: ENSPPAP00000042933   ⟸   ENSPPAT00000065866
RefSeq Acc Id: ENSPPAP00000042932   ⟸   ENSPPAT00000065865
RefSeq Acc Id: ENSPPAP00000042931   ⟸   ENSPPAT00000065864
RefSeq Acc Id: ENSPPAP00000042930   ⟸   ENSPPAT00000065863
RefSeq Acc Id: ENSPPAP00000042929   ⟸   ENSPPAT00000065862
RefSeq Acc Id: XP_054960338   ⟸   XM_055104363
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054960337   ⟸   XM_055104362
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054960336   ⟸   XM_055104361
- Peptide Label: isoform X1
Protein Domains
EGF-like   G-protein coupled receptors family 2 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000044011 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000065860.1 UniProtKB/TrEMBL
  ENSPPAT00000065862.1 UniProtKB/TrEMBL
  ENSPPAT00000065863.1 UniProtKB/TrEMBL
  ENSPPAT00000065864.1 UniProtKB/TrEMBL
  ENSPPAT00000065865.1 UniProtKB/TrEMBL
  ENSPPAT00000065866.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.220.50 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_ADGRE2_ADGRE5 UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
NCBI Gene ADGRE2 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR E2 UniProtKB/TrEMBL
  ADHESION G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
PRINTS CD97PROTEIN UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A2R9CLR5_PANPA UniProtKB/TrEMBL
  A0A2R9CLT2_PANPA UniProtKB/TrEMBL
  A0A2R9CLV5_PANPA UniProtKB/TrEMBL
  A0A2R9CNT2_PANPA UniProtKB/TrEMBL
  A0A2R9CTB3_PANPA UniProtKB/TrEMBL
  A0A2R9CTB6_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 LOC100974936  adhesion G protein-coupled receptor E2  ADGRE2  adhesion G protein-coupled receptor E2  Symbol and/or name change 5135510 APPROVED