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18 records found for search term Tnfsf10
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
628734Tnfsf10TNF superfamily member 10ENCODES a protein that exhibits cytokine activity (ortholog); identical protein binding (ortholog); TRAIL binding (ortholog); INVOLVED IN male gonad development; positive regulation of apoptotic process; response to insulin; PARTICIPATES IN Trail mediated signaling pathway; apoptotic cell death path2112136550112155903Rat553symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
732827Tnfsf10tumor necrosis factor (ligand) superfamily, member 10Enables TRAIL binding activity and tumor necrosis factor receptor superfamily binding activity. Acts upstream of or within positive regulation of extrinsic apoptotic signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in central 32737122627393814Mouse594symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1344832TNFSF10TNF superfamily member 10The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.3172505508172523430Human574symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8830376Tnfsf10TNF superfamily member 10ENCODES a protein that exhibits cytokine activity (ortholog); identical protein binding (ortholog); TRAIL binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog);NW_00495542025503922566448Chinchilla58symbolgene, protein-coding, MODEL [RefSeq]
11711830TNFSF10TNF superfamily member 10ENCODES a protein that exhibits cytokine activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of extrinsic apoptotic signaling pathway (ortholog3169512491169530706Bonobo72symbolgene, protein-coding, MODEL [RefSeq]
12252219TNFSF10TNF superfamily member 10ENCODES a protein that exhibits cytokine activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of extrinsic apoptotic signaling pathway (ortholog343671924936734989Dog79symbolgene, protein-coding, PROVISIONAL [RefSeq]
12652388Tnfsf10TNF superfamily member 10ENCODES a protein that exhibits cytokine activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of extrinsic apoptotic signaling pathway (orthologNW_004936593212642230645Squirrel72symbolgene, protein-coding, MODEL [RefSeq]
284084478tnfsf10Tropical Clawed Frogsymbolgene, null
18928578Tnfsf10TNF superfamily member 10ENCODES a protein that exhibits cytokine activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of extrinsic apoptotic signaling pathway (orthologNaked Mole-Rat73symbolgene, protein-coding, MODEL [RefSeq]
625862778Tnfsf10TNF superfamily member 10ENCODES a protein that exhibits cytokine activity (ortholog); identical protein binding (ortholog); TRAIL binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog);Black Rat58symbolgene, protein-coding, MODEL [RefSeq]
13934813TNFSF10TNF superfamily member 10ENCODES a protein that exhibits identical protein binding (ortholog); TRAIL binding (ortholog); tumor necrosis factor receptor superfamily binding (ortholog); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of canonical NF-kappaPig77symbolgene, protein-coding, PROVISIONAL [RefSeq]
18641143TNFSF10TNF superfamily member 10ENCODES a protein that exhibits cytokine activity (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN male gonad development (ortholog); positive regulation of apoptotic process (ortholog); positive regulation of extrinsic apoptotic signaling pathway (orthologGreen Monkey72symbolgene, protein-coding, MODEL [RefSeq]
285440082tnfsf10.LAfrican Clawed Frogsymbolgene, null
285601978tnfsf10.SAfrican Clawed Frogsymbolgene, null
288070974tnfsf10lTropical Clawed Frogsymbolgene, null
1345195FADDFas associated via death domainThe protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10117020329670207390Human461descriptiongene, protein-coding, REVIEWED [RefSeq]
1317580TNFRSF10ATNF receptor superfamily member 10aThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FA82319045223225102Human286descriptiongene, protein-coding, REVIEWED [RefSeq]
1346665TNFRSF10BTNF receptor superfamily member 10bThe protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosi82302013323069031Human382descriptiongene, protein-coding, REVIEWED [RefSeq]