| 1305533 | Tbce | tubulin folding cofactor E | INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); INTERAC TS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 17 | 55983627 | 56031578 | Rat | 112 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1313614 | TBCE | tubulin folding cofactor E | Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] | 1 | 235367427 | 235452443 | Human | 290 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1313615 | Tbce | tubulin-specific chaperone E | This gene encodes a tubulin binding cofactor that participates in microtubule dynamics. A mouse model of progressive motor neuropathy (pmn) was discovered to harbor a single amino acid deletion in this gene. Mice that are homozygous for pmn allele exhibit progressive atrophy and premature death due to respiratory failure. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015] | 13 | 14172532 | 14214235 | Mouse | 128 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8961556 | Tbce | tubulin folding cofactor E | INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog) | NW_004955492 | 4502705 | 4573126 | Chinchilla | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11896006 | TBCE | tubulin folding cofactor E | ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dyspla sia (ortholog); FOUND IN cytoskeleton (inferred); ribonucleoprotein complex (inferred); ribosome (inferred) | 1 | 210881078 | 211008686 | Bonobo | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12360543 | TBCE | tubulin folding cofactor E | INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred) | 4 | 4490892 | 4569401 | Dog | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12571802 | Tbce | tubulin folding cofactor E | INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoskeleton (inferred) | NW_004936484 | 17048187 | 17097414 | Squirrel | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13989656 | TBCE | tubulin folding cofactor E | INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred) | | | | Pig | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14381294 | Tbce | | | | | | Fly | | symbol | gene, null |
| 18642824 | TBCE | tubulin folding cofactor E | INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoplasm (inferred) | | | | Green Monkey | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18931742 | Tbce | tubulin folding cofactor E | INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cytoskeleton (inferred) | | | | Naked Mole-Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155254169 | tbce | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626001603 | Tbce | tubulin folding cofactor E | INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); developmental growth (ortholog); ASSOCIATED WITH bacterial infectious disease (ortholog); Craniofacial Abnormalities (ortholog); Desbuquois dysplasia (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14381297 | tbce-1 | | | | | | Roundworm | | symbol | gene, null |
| 155232083 | tbce.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 16570654 | AL357556.4 | novel transcript, antisense to TBCE | | 1 | 235366353 | 235367420 | Human | | name | gene, ncrna, MODEL [RefSeq] |
| 1308880 | Tbcel | tubulin folding cofactor E-like | FOUND IN cytoskeleton (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 8 | 51692660 | 51751560 | Rat | 80 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1550784 | Tbcel | tubulin folding cofactor E-like | Predicted to enable alpha-tubulin binding activity. Predicted to be involved in microtubule cytoskeleton organization; post-chaperonin tubulin folding pathway; and tubulin complex assembly. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. Orthologous to human TBCE ='font-weight:700;'>TBCEL (tubulin folding cofactor E like). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 42323612 | 42383534 | Mouse | 83 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1606678 | TBCEL | tubulin folding cofactor E like | Predicted to enable alpha-tubulin binding activity. Predicted to be involved in microtubule cytoskeleton organization; post-chaperonin tubulin folding pathway; and tubulin complex assembly. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 121024102 | 121090776 | Human | 81 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8899186 | Tbcel | tubulin folding cofactor E like | | NW_004955412 | 21969521 | 22044348 | Chinchilla | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12406847 | TBCEL | tubulin folding cofactor E like | | 5 | 12963356 | 13035525 | Dog | 2 | symbol | gene, protein-coding |
| 18904163 | Tbcel | tubulin folding cofactor E like | FOUND IN cytoskeleton (inferred) | | | | Naked Mole-Rat | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257851 | tbcel | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 329329929 | TBCEL | tubulin folding cofactor E like | FOUND IN cytoskeleton (inferred) | | | | Dog | 6 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 329332765 | TBCEL | tubulin folding cofactor E like | FOUND IN cytoskeleton (inferred) | | | | Pig | 1 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 155251636 | tbcel.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155250226 | tbcel.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 21409777 | TBCEL-TECTA | TBCEL-TECTA readthrough | Predicted to be involved in cell-matrix adhesion. Predicted to be located in extracellular region; plasma membrane; and side of membrane. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 121024102 | 121191490 | Human | 10 | symbol , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 11882648 | LOC100980308 | tubulin-specific chaperone cofactor E-like protein | ENCODES a protein that exhibits extracellular matrix structural constituent (inferred); INVOLVED IN cell-matrix adhesion (inferred); sensory perception of sound (inferred); FOUND IN cell periphery (inferred); cytoskeleton (inferred); extracellular matrix (inferred) | 11 | 115867514 | 116038193 | Bonobo | 11 | ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12586303 | LOC101975324 | tubulin-specific chaperone cofactor E-like protein | ENCODES a protein that exhibits extracellular matrix structural constituent (inferred); INVOLVED IN auditory receptor cell stereocilium organization (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 12 (ortholog); autosomal recessive nonsyndromic deafness 21 (ortholog); Hearing Lo ss (ortholog); FOUND IN cell periphery (inferred); cytoskeleton (inferred); extracellular matrix (inferred) | NW_004936542 | 5884624 | 5951260 | Squirrel | 18 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18742061 | LOC103248666 | tubulin-specific chaperone cofactor E-like protein | ENCODES a protein that exhibits extracellular matrix structural constituent (inferred); INVOLVED IN auditory receptor cell stereocilium organization (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 12 (ortholog); autosomal recessive nonsyndromic deafness 21 (ortholog); Hearing Lo ss (ortholog); FOUND IN cell periphery (inferred); cytoskeleton (inferred); extracellular matrix (inferred) | | | | Green Monkey | 18 | ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14260974 | TECTA | tectorin alpha | ENCODES a protein that exhibits extracellular matrix structural constituent (inferred); INVOLVED IN auditory receptor cell stereocilium organization (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 12 (ortholog); autosomal recessive nonsyndromic deafness 21 (ortholog); Hearing Lo ss (ortholog); FOUND IN cell periphery (inferred); cytoskeleton (inferred); extracellular matrix (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 20 | ensembl_gene_symbol | gene, protein-coding, INFERRED [RefSeq] |