TBCE (tubulin folding cofactor E) - Rat Genome Database

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Gene: TBCE (tubulin folding cofactor E) Pan paniscus
Analyze
Symbol: TBCE
Name: tubulin folding cofactor E
RGD ID: 11896006
Description: ENCODES a protein that exhibits structural constituent of ribosome (inferred); INVOLVED IN adult locomotory behavior (inferred); axonogenesis (inferred); cytoskeleton organization (inferred); ASSOCIATED WITH bacterial infectious disease (ortholog); Chediak-Higashi syndrome (ortholog); common variable immunodeficiency 14 (ortholog); FOUND IN cytoskeleton (inferred); ribonucleoprotein complex (inferred); ribosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tubulin-specific chaperone E
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2113,729,178 - 13,856,775 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1113,941,276 - 14,044,027 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01210,881,078 - 211,008,686 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11215,929,658 - 216,020,613 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,929,658 - 216,020,613 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBCEBonoboDwarfism  ISOTBCE (Homo sapiens)9068941Kenny-Caffey syndrome , OMIM:244460 RGDPMID:12389028 and REF_RGD_ID:1599303
TBCEBonobohypoparathyroidism  ISOTBCE (Homo sapiens)9068941hypoparathyroidism-retardation-dysmorphism syndrome and OMIM:241410 RGDPMID:12389028 and REF_RGD_ID:1599303
1 to 12 of 12 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBCEBonoboChediak-Higashi syndrome  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Chédiak-Higashi syndromeClinVarPMID:11857544 more ...
TBCEBonobocommon variable immunodeficiency 14  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency more ...ClinVar 
TBCEBonobocongenital muscular dystrophy-dystroglycanopathy type A11  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a and 11ClinVarPMID:23453667 more ...
TBCEBonobodisorder of sexual development  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Disorder of sexual differentiationClinVarPMID:16199547 more ...
TBCEBonobogastrointestinal stromal tumor  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
TBCEBonobogenetic disease  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:12389028 more ...
TBCEBonobohypoparathyroidism-retardation-dysmorphism syndrome  ISOTBCE (Homo sapiens)8554872ClinVar more ...ClinVarPMID:12389028 more ...
TBCEBonoboKenny-Caffey syndrome type 1  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive Kenny-Caffey syndromeClinVarPMID:12389028 more ...
TBCEBonobomicrocephaly  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: MicrocephalyClinVarPMID:25741868 and PMID:28492532
TBCEBonoboparathyroid carcinoma  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
TBCEBonoboPituitary Stalk Interruption Syndrome  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Pituitary stalk interruption syndromeClinVarPMID:25741868
TBCEBonoboProgressive Encephalopathy with Amyotrophy and Optic Atrophy  ISOTBCE (Homo sapiens)8554872ClinVar Annotator: match by term: Encephalopathy more ...ClinVarPMID:12389028 more ...
1 to 12 of 12 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBCEBonobobacterial infectious disease  ISOTBCE (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:12389028
TBCEBonoboCraniofacial Abnormalities  ISOTBCE (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:12389028
TBCEBonoboFacies  ISOTBCE (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:12389028
TBCEBonoboKenny-Caffey syndrome type 2  ISOTBCE (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:12389028
TBCEBonoboosteosclerosis  ISOTBCE (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:12389028


Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBCEBonoboadult locomotory behavior acts_upstream_of_or_withinIEAUniProtKB:Q8CIV8 and ensembl:ENSMUSP00000047880150520179 EnsemblGO_REF:0000107
TBCEBonoboaxonogenesis acts_upstream_of_or_withinIEAUniProtKB:Q8CIV8 and ensembl:ENSMUSP00000047880150520179 EnsemblGO_REF:0000107
TBCEBonobocytoskeleton organization involved_inIEAPANTHER:PTN009033728150520179 TreeGrafterGO_REF:0000118
TBCEBonobodevelopmental growth acts_upstream_of_or_withinIEAUniProtKB:Q8CIV8 and ensembl:ENSMUSP00000047880150520179 EnsemblGO_REF:0000107
TBCEBonobomicrotubule cytoskeleton organization involved_inIEAUniProtKB:Q15813 and ensembl:ENSP00000494796150520179 EnsemblGO_REF:0000107
TBCEBonobomicrotubule cytoskeleton organization acts_upstream_of_or_withinIEAUniProtKB:Q8CIV8 and ensembl:ENSMUSP00000047880150520179 EnsemblGO_REF:0000107
TBCEBonobomitotic spindle organization involved_inIEAUniProtKB:Q15813 and ensembl:ENSP00000494796150520179 EnsemblGO_REF:0000107
TBCEBonobomuscle atrophy acts_upstream_of_or_withinIEAUniProtKB:Q8CIV8 and ensembl:ENSMUSP00000047880150520179 EnsemblGO_REF:0000107
TBCEBonoboperipheral nervous system neuron axonogenesis acts_upstream_of_or_withinIEAUniProtKB:Q8CIV8 and ensembl:ENSMUSP00000047880150520179 EnsemblGO_REF:0000107
TBCEBonobopost-chaperonin tubulin folding pathway involved_inIEAUniProtKB:Q15813 and ensembl:ENSP00000494796150520179 EnsemblGO_REF:0000107
TBCEBonobopost-embryonic development acts_upstream_of_or_withinIEAUniProtKB:Q8CIV8 and ensembl:ENSMUSP00000047880150520179 EnsemblGO_REF:0000107
TBCEBonobotranslation involved_inIEAInterPro:IPR001931150520179 InterProGO_REF:0000002
1 to 12 of 12 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBCEBonobocytoskeleton located_inIEAUniProtKB-KW:KW-0206150520179 UniProtGO_REF:0000043
TBCEBonobocytoskeleton located_inIEAUniProtKB-SubCell:SL-0090150520179 UniProtGO_REF:0000044
TBCEBonoboribonucleoprotein complex part_ofIEAUniProtKB-KW:KW-0687150520179 UniProtGO_REF:0000043
TBCEBonoboribosome located_inIEAInterPro:IPR001931150520179 InterProGO_REF:0000002
TBCEBonoboribosome located_inIEAUniProtKB-KW:KW-0689150520179 UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TBCEBonoboprotein binding enablesISOUniProtKB:Q9BTW99068941 PMID:27666374UniProtPMID:27666374
TBCEBonobostructural constituent of ribosome enablesIEAInterPro:IPR001931150520179 InterProGO_REF:0000002

PMID:22301074   PMID:30032202  



TBCE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2113,729,178 - 13,856,775 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1113,941,276 - 14,044,027 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01210,881,078 - 211,008,686 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11215,929,658 - 216,020,613 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,929,658 - 216,020,613 (+)Ensemblpanpan1.1panPan2
TBCE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381235,367,427 - 235,452,443 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1235,367,360 - 235,452,443 (+)EnsemblGRCh38hg38GRCh38
GRCh371235,530,742 - 235,615,756 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361233,597,351 - 233,678,903 (+)NCBINCBI36Build 36hg18NCBI36
Build 341231,856,811 - 231,938,321NCBI
Celera1208,773,486 - 208,855,524 (+)NCBICelera
Cytogenetic Map1q42.3NCBI
HuRef1205,979,723 - 206,063,927 (+)NCBIHuRef
CHM1_11236,803,044 - 236,884,877 (+)NCBICHM1_1
T2T-CHM13v2.01234,759,155 - 234,848,336 (+)NCBIT2T-CHM13v2.0
Tbce
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391314,172,532 - 14,214,235 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1314,172,534 - 14,214,223 (-)EnsemblGRCm39 Ensembl
GRCm381313,997,947 - 14,039,650 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1313,997,949 - 14,039,638 (-)EnsemblGRCm38mm10GRCm38
MGSCv371314,090,218 - 14,131,867 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361313,790,077 - 13,831,726 (-)NCBIMGSCv36mm8
Celera1314,305,650 - 14,346,667 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map135.29NCBI
Tbce
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81755,983,627 - 56,031,578 (+)NCBIGRCr8
mRatBN7.21751,290,143 - 51,336,090 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1751,290,202 - 51,336,089 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1754,459,035 - 54,504,526 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01758,461,975 - 58,507,461 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01752,593,177 - 52,638,508 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01753,983,126 - 54,029,028 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1753,983,182 - 54,029,027 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01751,676,746 - 51,723,130 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41759,485,451 - 59,533,041 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11759,496,283 - 59,543,873 (+)NCBI
Celera1747,297,977 - 47,343,424 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
Tbce
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554924,502,897 - 4,558,697 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554924,502,705 - 4,573,126 (-)NCBIChiLan1.0ChiLan1.0
TBCE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.144,490,892 - 4,569,401 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl44,490,994 - 4,569,357 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha44,473,098 - 4,551,614 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.044,512,625 - 4,591,187 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl44,512,629 - 4,591,155 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.144,523,866 - 4,602,326 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.044,641,317 - 4,719,844 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.044,862,950 - 4,941,668 (-)NCBIUU_Cfam_GSD_1.0
Tbce
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934440,882,963 - 40,931,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648417,046,284 - 17,095,744 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648417,048,187 - 17,097,414 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBCE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1455,816,668 - 55,901,171 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11455,816,663 - 55,901,215 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21459,954,790 - 59,986,383 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBCE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12572,544,942 - 72,616,716 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2572,545,012 - 72,612,622 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605574,568,863 - 74,652,576 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbce
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477515,067,044 - 15,133,008 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477515,067,044 - 15,132,690 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSPPAT00000033593   ⟹   ENSPPAP00000010938
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1215,929,658 - 216,020,613 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000033598   ⟹   ENSPPAP00000010943
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1215,945,876 - 216,020,407 (+)Ensembl
RefSeq Acc Id: XM_034949361   ⟹   XP_034805252
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2113,729,178 - 13,764,044 (-)NCBI
NHGRI_mPanPan1113,941,276 - 13,976,112 (-)NCBI
Mhudiblu_PPA_v01210,973,847 - 211,008,686 (+)NCBI
RefSeq Acc Id: XM_034949362   ⟹   XP_034805253
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2113,729,178 - 13,764,044 (-)NCBI
NHGRI_mPanPan1113,941,276 - 13,976,112 (-)NCBI
Mhudiblu_PPA_v01210,973,847 - 211,008,686 (+)NCBI
RefSeq Acc Id: XM_055099979   ⟹   XP_054955954
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2113,729,178 - 13,830,765 (-)NCBI
NHGRI_mPanPan1113,941,276 - 14,044,027 (-)NCBI
RefSeq Acc Id: XM_055100072   ⟹   XP_054956047
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2113,729,178 - 13,827,848 (-)NCBI
NHGRI_mPanPan1113,941,276 - 14,040,333 (-)NCBI
RefSeq Acc Id: XM_063595534   ⟹   XP_063451604
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2113,729,178 - 13,830,765 (-)NCBI
RefSeq Acc Id: XM_063595546   ⟹   XP_063451616
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2113,729,178 - 13,830,740 (-)NCBI
RefSeq Acc Id: XM_063595552   ⟹   XP_063451622
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2113,729,178 - 13,856,775 (-)NCBI
RefSeq Acc Id: XP_034805252   ⟸   XM_034949361
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034805253   ⟸   XM_034949362
- Peptide Label: isoform X5
Ensembl Acc Id: ENSPPAP00000010943   ⟸   ENSPPAT00000033598
Ensembl Acc Id: ENSPPAP00000010938   ⟸   ENSPPAT00000033593
RefSeq Acc Id: XP_054955954   ⟸   XM_055099979
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A128 (UniProtKB/TrEMBL)
CAP-Gly



1 to 29 of 29 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000028683 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000033593.1 UniProtKB/TrEMBL
  ENSPPAT00000033598.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.190 UniProtKB/TrEMBL
  3.30.1230.20 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
InterPro CAP-Gly_dom_sf UniProtKB/TrEMBL
  CAP-Gly_domain UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  Ribosomal_S21e UniProtKB/TrEMBL
  Ribosomal_S21e_sf UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  Ubl_TBCE UniProtKB/TrEMBL
NCBI Gene TBCE ENTREZGENE
PANTHER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED UniProtKB/TrEMBL
  LEUCINE RICH REPEAT PROTEIN UniProtKB/TrEMBL
Pfam CAP_GLY UniProtKB/TrEMBL
  Ribosomal_S21e UniProtKB/TrEMBL
  Ubiquitin_2 UniProtKB/TrEMBL
PROSITE CAP_GLY_1 UniProtKB/TrEMBL
  CAP_GLY_2 UniProtKB/TrEMBL
SMART CAP_GLY UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  SSF74924 UniProtKB/TrEMBL
UniProt A0A2R9A128 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A137_PANPA UniProtKB/TrEMBL
1 to 29 of 29 rows