| 1311807 | Osr1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell differentiation (ortholog); cell proliferation involved in kidney development (ortholog); cellular response to retinoic acid (ortholog); FOUND IN cell cortex; cytosol; nucleus (ortholog); INTER ACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 6 | 38088688 | 38100010 | Rat | 238 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1605876 | OSR1 | odd-skipped related transcription factor 1 | Enables sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transporter activity; positive regulation of gastrulation; and pronephros development. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025] | 2 | 19344874 | 19358623 | Human | 199 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1620082 | Osr1 | odd-skipped related transcription factor 1 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic limb morphogenesis; kidney development; and regulation of transcr iption by RNA polymerase II. Acts upstream of or within gonad development; intermediate mesoderm development; and metanephros development. Predicted to be located in cell cortex and cytosol. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; genitourinary system; and limb. Orthologous to human OSR1 (odd-skipped related transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 9624442 | 9631500 | Mouse | 227 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8865621 | Osr1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell differentiation (ortholog); cell proliferation involved in kidney development (ortholog); cellular response to retinoic acid (ortholog); FOUND IN cell cortex (ortholog); cytosol (ortholog); nuc leus (ortholog) | NW_004955469 | 1954470 | 1961344 | Chinchilla | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11993236 | OSR1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); RNA polymerase II transcription regulatory region sequence-specific DNA binding (inferred); INVOLVED IN gonad development (ortholog); heart development (ort holog); intermediate mesoderm development (ortholog); FOUND IN cell cortex (ortholog); cytosol (ortholog) | 2A | 19333101 | 19340267 | Bonobo | 66 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12052885 | OSR1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits metal ion binding (inferred); sequence-specific double-stranded DNA binding (inferred); zinc ion binding (inferred); INVOLVED IN gonad development (ortholog); heart development (ortholog); intermediate mesoderm development (ortholog); FOUND IN cell cortex (ortholog); cytosol (ortholog); INTERACTS WITH bisphenol A | 17 | 14508543 | 14515657 | Dog | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12511101 | Osr1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); RNA polymerase II transcription regulatory region sequence-specific DNA binding (inferred); INVOLVED IN gonad development (ortholog); heart development (ort holog); intermediate mesoderm development (ortholog); FOUND IN cell cortex (ortholog); cytosol (ortholog) | NW_004936493 | 11888024 | 11895058 | Squirrel | 66 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234089 | osr1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14033874 | OSR1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits metal ion binding (inferred); sequence-specific double-stranded DNA binding (inferred); zinc ion binding (inferred); INVOLVED IN gonad development (ortholog); heart development (ortholog); intermediate mesoderm development (ortholog); FOUND IN cell cortex (ortholog); cytosol (ortholog) | | | | Pig | 68 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18358116 | OSR1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); RNA polymerase II transcription regulatory region sequence-specific DNA binding (inferred); INVOLVED IN gonad development (ortholog); heart development (ort holog); intermediate mesoderm development (ortholog); FOUND IN cell cortex (ortholog); cytosol (ortholog) | | | | Green Monkey | 66 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625852775 | Osr1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell differentiation (ortholog); cell proliferation involved in kidney development (ortholog); cellular response to retinoic acid (ortholog); FOUND IN cell cortex (ortholog); cytosol (ortholog); nuc leus (ortholog) | | | | Black Rat | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18930678 | Osr1 | odd-skipped related transcription factor 1 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell differentiation (ortholog); cell proliferation involved in kidney development (ortholog); cellular response to retinoic acid (ortholog); FOUND IN cell cortex (ortholog); cytosol (ortholog) | | | | Naked Mole-Rat | 65 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237803 | osr1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155253485 | osr1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1303142 | Oser1 | oxidative stress responsive serine-rich 1 | INVOLVED IN cellular response to hydrogen peroxide; FOUND IN nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 3 | 172486417 | 172504607 | Rat | 86 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1350756 | OSER1 | oxidative stress responsive serine rich 1 | Predicted to be involved in cellular response to hydrogen peroxide. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 20 | 44195939 | 44211810 | Human | 84 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1310466 | Oxsr1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits protein serine/threonine kinase activity; ATP binding (ortholog); identical protein binding (ortholog); INVOLVED IN cell volume homeostasis (ortholog); cellular hyperosmotic response (ortholog); cellular hypotonic response (ortholog); ASSOCIATED WITH hypertension (ort holog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil | 8 | 127850481 | 127941518 | Rat | 168 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1351310 | OXSR1 | oxidative stress responsive kinase 1 | The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008] | 3 | 38164063 | 38255484 | Human | 158 | old_gene_name , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1553494 | Oxsr1 | oxidative-stress responsive 1 | Enables protein serine/threonine kinase activity. Involved in several processes, including cellular hypotonic response; chemokine (C-C motif) ligand 21 signaling pathway; and positive regulation of T cell chemotaxis. Predicted to be active in cytosol. Is expressed in loop of Henle distal straight tu bule and metanephros. Orthologous to human OXSR1 (oxidative stress responsive kinase 1). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 119067498 | 119154475 | Mouse | 177 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9036846 | Oxsr1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); ion channel regulator activity (ortholog); INVOLVED IN cell volume homeostasis (ortholog); cellular hyperosmotic response (ortholog); cellular hypotonic response (ortholog); ASSOCIATED WITH hypertension (or tholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog) | NW_004955427 | 25575655 | 25696356 | Chinchilla | 43 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11845961 | OXSR1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); ion channel regulator activity (inferred); INVOLVED IN protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH hypertension (ortholog); FOUND IN cytoplasm (inferred); cyt osol (inferred) | 3 | 38063299 | 38153609 | Bonobo | 63 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12138478 | OXSR1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); ion channel regulator activity (inferred); INVOLVED IN protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH hypertension (ortholog); FOUND IN cytoplasm (inferred); cyt osol (inferred) | 23 | 7931636 | 8026591 | Dog | 55 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12481040 | Oxsr1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); ion channel regulator activity (inferred); INVOLVED IN protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH hypertension (ortholog); FOUND IN cytoplasm (inferred); cyt osol (inferred) | NW_004936473 | 27559756 | 27658299 | Squirrel | 54 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13989722 | OXSR1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); ion channel regulator activity (ortholog); INVOLVED IN cell volume homeostasis (ortholog); cellular hypotonic response (ortholog); cellular response to chemokine (ortholog); ASSOCIATED WITH hypertension (or tholog); FOUND IN cytosol (ortholog) | | | | Pig | 56 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 18454376 | OXSR1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); ion channel regulator activity (inferred); INVOLVED IN protein autophosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH hypertension (ortholog); FOUND IN cytoplasm (inferred); cyt osol (inferred) | | | | Green Monkey | 61 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18913453 | Oxsr1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); ion channel regulator activity (ortholog); magnesium ion binding (ortholog); INVOLVED IN cell volume homeostasis (ortholog); cellular hyperosmotic response (ortholog); chemokine (C-X-C motif) ligand 12 signaling pathway (ortholog) ; ASSOCIATED WITH hypertension (ortholog); FOUND IN cytoplasm (ortholog) | | | | Naked Mole-Rat | 52 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626032142 | Oxsr1 | oxidative stress responsive kinase 1 | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); ion channel regulator activity (ortholog); INVOLVED IN cell volume homeostasis (ortholog); cellular hyperosmotic response (ortholog); cellular hypotonic response (ortholog); ASSOCIATED WITH hypertension (or tholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog) | | | | Black Rat | 43 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |