| 1347471 | GPR17 | G protein-coupled receptor 17 | Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within negative regulation of inflammatory response to antigenic stimulus. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 127646153 | 127652639 | Human | 90 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1589785 | Gpr17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding; INVOLVED IN oligodendrocyte differentiation; negative regulation of inflammatory response to antigenic stimulus (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); Insulin Resistance (orth olog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diethylstilbestrol | 18 | 23850460 | 23857381 | Rat | 83 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1614668 | Gpr17 | G protein-coupled receptor 17 | Predicted to enable G protein-coupled receptor activity and receptor serine/threonine kinase binding activity. Acts upstream of or within negative regulation of inflammatory response to antigenic stimulus. Predicted to be active in plasma membrane. Is expressed in central nervous system; gut; and ma le reproductive gland or organ. Orthologous to human GPR17 (G protein-coupled receptor 17). [provided by Alliance of Genome Resources, Apr 2025] | 18 | 32076052 | 32082925 | Mouse | 92 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8864466 | Gpr17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); oligodendrocyte differentiation (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); In sulin Resistance (ortholog) | NW_004955459 | 2890266 | 2903053 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12017488 | GPR17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); oligodendrocyte differentiation (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); In sulin Resistance (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 2B | 32623444 | 32630256 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12407738 | GPR17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); oligodendrocyte differentiation (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); In sulin Resistance (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 19 | 22958778 | 22968489 | Dog | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12567542 | Gpr17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); oligodendrocyte differentiation (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); In sulin Resistance (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936469 | 43652244 | 43656661 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14203175 | GPR17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); oligodendrocyte differentiation (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); In sulin Resistance (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18646410 | GPR17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); oligodendrocyte differentiation (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); In sulin Resistance (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929416 | Gpr17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); oligodendrocyte differentiation (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); In sulin Resistance (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867316 | GPR17 | G protein-coupled receptor 17 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 284003573 | gpr17 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625977732 | Gpr17 | G protein-coupled receptor 17 | ENCODES a protein that exhibits receptor serine/threonine kinase binding (ortholog); INVOLVED IN negative regulation of inflammatory response to antigenic stimulus (ortholog); oligodendrocyte differentiation (ortholog); ASSOCIATED WITH brain infarction (ortholog); Hypercholesterolemia (ortholog); In sulin Resistance (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284003978 | gpr17.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1557825 | Slc52a2 | solute carrier protein 52, member 2 | Enables riboflavin transmembrane transporter activity. Involved in flavin adenine dinucleotide biosynthetic process and riboflavin metabolic process. Is active in plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in Brown-Vialetto-Van Laere syndrome 2 and riboflavin d eficiency. Orthologous to human SLC52A1 (solute carrier family 52 member 1) and SLC52A2 (solute carrier family 52 member 2). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 76422994 | 76432078 | Mouse | 110 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1353149 | GPR171 | G protein-coupled receptor 171 | Predicted to enable G protein-coupled purinergic nucleotide receptor activity; neuropeptide binding activity; and neuropeptide receptor activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of feeding behavior; and regulation of s ensory perception of pain. Predicted to act upstream of or within negative regulation of myeloid cell differentiation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 151197754 | 151203216 | Human | 78 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1585271 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); neuropeptide binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ort holog); negative regulation of myeloid cell differentiation (ortholog); FOUND IN plasma membrane; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 145510305 | 145515392 | Rat | 84 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1619850 | Gpr171 | G protein-coupled receptor 171 | Enables neuropeptide binding activity and neuropeptide receptor activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of feeding behavior; and regulation of sensory perception of pain. Acts upstream of or within negative regulation of myeloid cel l differentiation. Located in plasma membrane. Orthologous to human GPR171 (G protein-coupled receptor 171). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 59003869 | 59009242 | Mouse | 72 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8773861 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); neuropeptide binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); G protein-coupled receptor signaling p athway (ortholog); negative regulation of myeloid cell differentiation (ortholog); FOUND IN plasma membrane (ortholog) | NW_004955448 | 2335560 | 2341261 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11789299 | GPR171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled purinergic nucleotide receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 3 | 148226394 | 148231792 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12078815 | GPR171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled receptor activity (inferred); neuropeptide binding (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred ) | 23 | 45782265 | 45784517 | Dog | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12670347 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled purinergic nucleotide receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936758 | 1480035 | 1481490 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14276722 | GPR171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled receptor activity (inferred); neuropeptide binding (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred ) | | | | Pig | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18611864 | GPR171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (inferred); G protein-coupled purinergic nucleotide receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of myeloid cell differentiation (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18915503 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); neuropeptide binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); negative regulation of myeloid cell di fferentiation (ortholog); regulation of feeding behavior (ortholog); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284119962 | gpr171 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625986029 | Gpr171 | G protein-coupled receptor 171 | ENCODES a protein that exhibits G protein-coupled peptide receptor activity (ortholog); neuropeptide binding (ortholog); neuropeptide receptor activity (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); G protein-coupled receptor signaling p athway (ortholog); negative regulation of myeloid cell differentiation (ortholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 620748 | Gpr173 | G-protein coupled receptor 173 | ENCODES a protein that exhibits gonadotropin-releasing hormone receptor activity (ortholog); INVOLVED IN negative regulation of neuron migration (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH ammonium chloride; bisphenol A; vinclozolin | X | 24925634 | 24950485 | Rat | 57 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1347737 | GPR173 | G protein-coupled receptor 173 | This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues. [provided by RefSeq, Nov 2009] | X | 53048789 | 53080615 | Human | 60 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1551591 | Gpr173 | G-protein coupled receptor 173 | Enables gonadotropin-releasing hormone receptor activity. Acts upstream of or within negative regulation of neuron migration. Predicted to be active in plasma membrane. Is expressed in gut; nervous system; and sensory organ. Orthologous to human GPR173 (G protei n-coupled receptor 173). [provided by Alliance of Genome Resources, Apr 2025] | X | 151126594 | 151151763 | Mouse | 61 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8884691 | Gpr173 | G protein-coupled receptor 173 | ENCODES a protein that exhibits gonadotropin-releasing hormone receptor activity (ortholog); INVOLVED IN negative regulation of neuron migration (ortholog) | NW_004955475 | 137239 | 158670 | Chinchilla | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12029545 | GPR173 | G protein-coupled receptor 173 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); gonadotropin-releasing hormone receptor activity (inferred); INVOLVED IN negative regulation of neuron migration (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | X | 45262876 | 45292398 | Bonobo | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12203674 | GPR173 | G protein-coupled receptor 173 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN negative regulation of neuron migration (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | X | 45009157 | 45033188 | Dog | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12495517 | Gpr173 | G protein-coupled receptor 173 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); gonadotropin-releasing hormone receptor activity (inferred); INVOLVED IN negative regulation of neuron migration (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936751 | 61770 | 82769 | Squirrel | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13912388 | GPR173 | G protein-coupled receptor 173 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); gonadotropin-releasing hormone receptor activity (inferred); INVOLVED IN negative regulation of neuron migration (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18422857 | GPR173 | G protein-coupled receptor 173 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); gonadotropin-releasing hormone receptor activity (inferred); INVOLVED IN negative regulation of neuron migration (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922417 | Gpr173 | G protein-coupled receptor 173 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); gonadotropin-releasing hormone receptor activity (inferred); INVOLVED IN negative regulation of neuron migration (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232597 | gpr173 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625894996 | Gpr173 | G protein-coupled receptor 173 | ENCODES a protein that exhibits gonadotropin-releasing hormone receptor activity (ortholog); INVOLVED IN negative regulation of neuron migration (ortholog) | | | | Black Rat | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1345699 | GPR174 | G protein-coupled receptor 174 | This gene encodes a protein belonging to the G protein-coupled receptor superfamily. These proteins are characterized by the presence of seven alpha-helical transmembrane domains, and they activate or interact with various endogenous or exogenous ligands, including neurotransmitters, hormones, and o dorant and taste substances. This family member is classified as an orphan receptor because the cognate ligand has not been identified. [provided by RefSeq, Sep 2011] | X | 79144688 | 79175318 | Human | 45 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1564689 | Gpr174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (ortholog); G protein-coupled receptor activity (ortholog); INVOLVED IN negative regulation of interleukin-2 production (ortholog); T cell homeostasis (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachloro dibenzodioxine; acetamide; alpha-Zearalanol | X | 76428274 | 76469020 | Rat | 45 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1622120 | Gpr174 | G protein-coupled receptor 174 | Enables bioactive lipid receptor activity. Acts upstream of or within T cell homeostasis. Predicted to be located in centriolar satellite and intracellular membrane-bounded organelle. Predicted to be active in plasma membrane. Orthologous to human GPR174 (G prot ein-coupled receptor 174). [provided by Alliance of Genome Resources, Apr 2025] | X | 106299484 | 106340377 | Mouse | 58 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8969719 | Gpr174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (ortholog); G protein-coupled receptor activity (ortholog); INVOLVED IN negative regulation of interleukin-2 production (ortholog); T cell homeostasis (ortholog); FOUND IN plasma membrane (ortholog) | NW_004955557 | 2071792 | 2102865 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11674779 | GPR174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN T cell homeostasis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | X | 68284983 | 68286466 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12208615 | GPR174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN T cell homeostasis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | X | 61361095 | 61423145 | Dog | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12599170 | Gpr174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN T cell homeostasis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936547 | 1170718 | 1171958 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13983603 | GPR174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN T cell homeostasis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18393963 | GPR174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN T cell homeostasis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921577 | Gpr174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (ortholog); INVOLVED IN negative regulation of interleukin-2 production (ortholog); T cell homeostasis (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155249464 | gpr174 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626094916 | Gpr174 | G protein-coupled receptor 174 | ENCODES a protein that exhibits bioactive lipid receptor activity (ortholog); G protein-coupled receptor activity (ortholog); INVOLVED IN negative regulation of interleukin-2 production (ortholog); T cell homeostasis (ortholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 621718 | Gpr176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); circadian behavior (ortholog); G protein-coupled receptor signaling pathway (ortholog); FOUND IN plasma membrane (ortholog ); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 3 | 125690750 | 125791172 | Rat | 116 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 737562 | GPR176 | G protein-coupled receptor 176 | Members of the G protein-coupled receptor family, such as GPR176, are cell surface receptors involved in responses to hormones, growth factors, and neurotransmitters (Hata et al., 1995 [PubMed 7893747]).[supplied by OMIM, Jul 2008] | 15 | 39799008 | 39920266 | Human | 116 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1619683 | Gpr176 | G protein-coupled receptor 176 | Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and circadian behavior. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Located in plasma membrane. Is expressed in brain and genitourinary syst em. Orthologous to human GPR176 (G protein-coupled receptor 176). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 118107577 | 118205022 | Mouse | 111 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9043153 | Gpr176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); circadian behavior (ortholog); G protein-coupled receptor signaling pathway (ortholog); FOUND IN plasma membrane (ortholog ) | NW_004955416 | 6735790 | 6879078 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11913862 | GPR176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 15 | 18739092 | 18858618 | Bonobo | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12394095 | GPR176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 30 | 6990463 | 7120361 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12593182 | Gpr176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936471 | 3298247 | 3413093 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14226049 | GPR176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18426079 | GPR176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18912754 | Gpr176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); circadian behavior (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866334 | GPR176 | G protein-coupled receptor 176 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 155255851 | gpr176 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626140019 | Gpr176 | G protein-coupled receptor 176 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); circadian behavior (ortholog); G protein-coupled receptor signaling pathway (ortholog); FOUND IN plasma membrane (ortholog ) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1560033 | Gpr179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); visual perception (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); congenital stationary n ight blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN cell tip (ortholog); dendrite (ortholog); dendrite terminus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; trichloroethene | 10 | 82820954 | 82836833 | Rat | 54 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1601901 | GPR179 | G protein-coupled receptor 179 | This gene encodes a member of the glutamate receptor subfamily of G protein-coupled receptors. The encoded protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night b lindness type 1E. [provided by RefSeq, Apr 2012] | 17 | 38324571 | 38343956 | Human | 153 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1623813 | Gpr179 | G protein-coupled receptor 179 | Predicted to enable G protein-coupled receptor activity. Involved in visual perception. Acts upstream of or within protein localization to plasma membrane and response to light stimulus. Located in dendrite terminus. Is active in cell tip; dendrite; and postsynaptic membrane. Used to study congenita l stationary night blindness 1E. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1E. Orthologous to human GPR179 (G protein-coupled receptor 179). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 97222935 | 97243182 | Mouse | 58 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8904082 | Gpr179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); visual perception (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); congenital stationary n ight blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN cell tip (ortholog); dendrite (ortholog); dendrite terminus (ortholog) | NW_004955451 | 13545994 | 13560231 | Chinchilla | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11809820 | GPR179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); visual perception (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); congenital stationary n ight blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN cell tip (ortholog); dendrite (ortholog); dendrite terminus (ortholog) | 17 | 18928680 | 18949014 | Bonobo | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12430892 | GPR179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protein-membrane adaptor activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); conge nital stationary night blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN dendrite terminus (ortholog) | 9 | 23810560 | 23827684 | Dog | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12464437 | Gpr179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protein-membrane adaptor activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); conge nital stationary night blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN dendrite terminus (ortholog) | NW_004936490 | 13801514 | 13818666 | Squirrel | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13871614 | GPR179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protein-membrane adaptor activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); conge nital stationary night blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN dendrite terminus (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18600927 | GPR179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); protein-membrane adaptor activity (inferred); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); conge nital stationary night blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN dendrite terminus (ortholog) | | | | Green Monkey | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907499 | Gpr179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); visual perception (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); congenital stationary n ight blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN cell tip (ortholog); dendrite (ortholog); dendrite terminus (ortholog) | | | | Naked Mole-Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284632262 | gpr179 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625906725 | Gpr179 | G protein-coupled receptor 179 | ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN protein localization to plasma membrane (ortholog); response to light stimulus (ortholog); visual perception (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); congenital stationary n ight blindness 1B (ortholog); congenital stationary night blindness 1E (ortholog); FOUND IN cell tip (ortholog); dendrite (ortholog); dendrite terminus (ortholog) | | | | Black Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288053490 | gpr171.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284833294 | gpr171.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155232598 | gpr173.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155239499 | gpr173.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155245360 | gpr174.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155249463 | gpr174.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155258843 | gpr176.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286813605 | gpr179.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284632709 | gpr179.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14402306 | GPR176-DT | GPR176 divergent transcript | INTERACTS WITH lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteine | 15 | 39921024 | 39924899 | Human | 2 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1346676 | OXER1 | oxoeicosanoid receptor 1 | Enables G protein-coupled receptor activity and icosanoid binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 42762499 | 42764135 | Human | 33 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1350892 | TMEM181 | transmembrane protein 181 | The TMEM181 gene encodes a putative G protein-coupled receptor expressed on the cell surface (Carette et al., 2009 [PubMed 19965467]; Wollscheid et al., 2009 [PubMed 19349973]).[supplied by OMIM, Jan 2010] | 6 | 158536640 | 158635429 | Human | 54 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1620723 | Tmem181a | transmembrane protein 181A | Predicted to enable toxic substance binding activity. Is expressed in several structures, including cardiovascular system; central nervous system; gut; reproductive system; and trachea. Orthologous to human TMEM181 (transmembrane protein 181). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 6307001 | 6358589 | Mouse | 57 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620858 | Tpra1 | transmembrane protein adipocyte associated 1 | INVOLVED IN embryonic cleavage (ortholog); negative regulation of mitotic cell cycle phase transition (ortholog); FOUND IN plasma membrane; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; ammonium chloride | 4 | 122921304 | 122932519 | Rat | 81 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1354338 | TPRA1 | transmembrane protein adipocyte associated 1 | Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within embryonic cleavage and negative regulation of mitotic cell cycle phase transition. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 127571232 | 127598231 | Human | 84 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1618402 | Tpra1 | transmembrane protein, adipocyte asscociated 1 | Predicted to enable G protein-coupled receptor activity. Acts upstream of or within embryonic cleavage and negative regulation of mitotic cell cycle phase transition. Predicted to be active in plasma membrane. Is expressed in brain. Orthologous to human TPRA1 (transmembrane protein adipocyte associa ted 1). [provided by Alliance of Genome Resources, Apr 2025] | 6 | 88879238 | 88889216 | Mouse | 81 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12099396 | TPRA1 | transmembrane protein adipocyte associated 1 | INVOLVED IN embryonic cleavage (ortholog); negative regulation of mitotic cell cycle phase transition (ortholog); FOUND IN plasma membrane (ortholog) | 20 | 1661980 | 1680111 | Dog | 9 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 735139 | Wls | Wnt ligand secretion mediator | ENCODES a protein that exhibits mu-type opioid receptor binding; identical protein binding (ortholog); Wnt-protein binding (ortholog); INVOLVED IN positive regulation of dendrite morphogenesis; anterior/posterior axis specification (ortholog); cementum mineralization (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Zaki syndrome (ortholog); FOUND IN cytoplasm; dendrite cytoplasm; dendrite membrane; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol | 2 | 251590653 | 251705991 | Rat | 186 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1550386 | Wls | wntless WNT ligand secretion mediator | Enables Wnt-protein binding activity. Involved in several processes, including brain development; cementum mineralization; and exocrine pancreas development. Acts upstream of or within Wnt protein secretion. Located in several cellular components, including Golgi apparatus; cytoplasmic vesicle; and endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and skin. Used to study Zaki syndrome. Human ortholog(s) of this gene implicated in Zaki syndrome. Orthologous to human WLS (Wnt ligand secretion mediator). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 159545287 | 159644302 | Mouse | 314 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1605334 | WLS | Wnt ligand secretion mediator | Enables Wnt-protein binding activity and identical protein binding activity. Involved in positive regulation of cell communication and protein transport. Located in several cellular components, including Golgi apparatus; early endosome; and endoplasmic reticulum membrane. Implicated in Zaki syndrome . [provided by Alliance of Genome Resources, Jul 2025] | 1 | 68098459 | 68232546 | Human | 226 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12430477 | WLS | Wnt ligand secretion mediator | ENCODES a protein that exhibits identical protein binding (ortholog); mu-type opioid receptor binding (ortholog); INVOLVED IN anterior/posterior axis specification (ortholog); cementum mineralization (ortholog); exocrine pancreas development (ortholog); PARTICIPATES IN Wnt signaling, canonical pathw ay; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Zaki syndrome (ortholog); FOUND IN cytoplasm (ortholog); dendrite cytoplasm (ortholog); dendrite membrane (ortholog) | 6 | 77053242 | 77146549 | Dog | 50 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 13954578 | WLS | Wnt ligand secretion mediator | ENCODES a protein that exhibits identical protein binding (ortholog); mu-type opioid receptor binding (ortholog); INVOLVED IN anterior/posterior axis specification (ortholog); cementum mineralization (ortholog); exocrine pancreas development (ortholog); PARTICIPATES IN Wnt signaling, canonical pathw ay; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Zaki syndrome (ortholog); FOUND IN cytoplasm (ortholog); dendrite cytoplasm (ortholog); dendrite membrane (ortholog) | | | | Pig | 50 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1346677 | SLC52A1 | solute carrier family 52 member 1 | Biological redox reactions require electron donors and acceptor. Vitamin B2 is the source for the flavin in flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) which are common redox reagents. This gene encodes a member of the riboflavin (vitamin B2) transporter family. Haploinsufficie ncy of this protein can cause maternal riboflavin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013] | 17 | 5032602 | 5042414 | Human | 91 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1349767 | SLC52A2 | solute carrier family 52 member 2 | This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and fl avin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012] | 8 | 144358552 | 144361272 | Human | 181 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1560410 | Slc52a2 | solute carrier family 52 member 2 | ENCODES a protein that exhibits riboflavin transmembrane transporter activity; 4-hydroxybutyrate receptor activity (ortholog); INVOLVED IN riboflavin transport; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 9 (ortholog); Brown-Vialetto-Van Laere syndrome (ortholog); Brown-Vialetto-Van La ere syndrome 1 (ortholog); FOUND IN plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; allethrin | 7 | 110126632 | 110146647 | Rat | 104 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12283919 | SLC52A2 | solute carrier family 52 member 2 | ENCODES a protein that exhibits 4-hydroxybutyrate receptor activity (ortholog); INVOLVED IN riboflavin transport (inferred); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 9 (ortholog); Brown-Vialetto-Van Laere syndrome (ortholog); Brown-Vialetto-Van Laere syndrome 1 (ortholog); FOUND IN plasma membrane (inferred) | 13 | 37779896 | 37786653 | Dog | 23 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 13982085 | SLC52A2 | solute carrier family 52 member 2 | ENCODES a protein that exhibits 4-hydroxybutyrate receptor activity (ortholog); riboflavin transmembrane transporter activity (ortholog); INVOLVED IN riboflavin transport (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 9 (ortholog); Brown-Vialetto-Van Laere syndrome (ortholog); Brown-Vialetto-Van Laere syndrome 1 (ortholog); FOUND IN plasma membrane (ortholog) | | | | Pig | 28 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 16562210 | AC023908.1 | novel transcript, sense overlapping GPR176 | | | | | Human | | name | gene, lncrna |
| 18928757 | Tpra1 | transmembrane protein adipocyte associated 1 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN embryonic cleavage (ortholog); negative regulation of mitotic cell cycle phase transition (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 8 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |