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Gene: GPR174 (G protein-coupled receptor 174) Homo sapiens
Symbol: GPR174
Name: G protein-coupled receptor 174
Description: Predicted to have G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to localize to the integral component of plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FKSG79; GPCR17; LYPSR3; probable G-protein coupled receptor 174
Mus musculus (house mouse) : Gpr174 (G protein-coupled receptor 174)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpr174 (G protein-coupled receptor 174)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpr174 (G protein-coupled receptor 174)
Pan paniscus (bonobo/pygmy chimpanzee) : GPR174 (G protein-coupled receptor 174)
Canis lupus familiaris (dog) : GPR174 (G protein-coupled receptor 174)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpr174 (G protein-coupled receptor 174)
Sus scrofa (pig) : GPR174 (G protein-coupled receptor 174)
Chlorocebus sabaeus (African green monkey) : GPR174 (G protein-coupled receptor 174)
Heterocephalus glaber (naked mole-rat) : Gpr174 (G protein-coupled receptor 174)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX79,144,663 - 79,175,315 (+)Ensembl
GRCh38X79,170,972 - 79,175,318 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X78,400,512 - 78,430,815 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X78,313,125 - 78,314,382 (+)NCBINCBI36hg18NCBI36
Build 34X78,232,613 - 78,233,871NCBI
CeleraX78,666,761 - 78,668,018 (+)NCBI
Cytogenetic MapXq21.1NCBI
HuRefX72,005,569 - 72,006,043 (+)NCBIHuRef
CHM1_1X78,319,671 - 78,320,928 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GPR174
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345699
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.