| 620713 | Fgfr1 | Fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding; protein-containing complex binding; signaling receptor binding; INVOLVED IN cellular response to histamine; cellular response to lipopolysaccharide; cellular response to nerve growth factor stimulus; PARTICIPATES IN cerium oxide nanopar ticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH Burns; Experimental Liver Cirrhosis; Experimental Seizures; FOUND IN perinuclear region of cytoplasm; glutamatergic synapse (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2-amino-2-deoxy-D-glucopyranose; 3,3',5-triiodo-L-thyronine | 16 | 73194631 | 73249855 | Rat | 539 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 732290 | FGFR1 | fibroblast growth factor receptor 1 | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length r epresentative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] | 8 | 38411143 | 38468635 | Human | 1343 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 732291 | Fgfr1 | fibroblast growth factor receptor 1 | Enables SH2 domain binding activity; fibroblast growth factor binding activity; and fibroblast growth factor receptor activity. Involved in several processes, including cementum mineralization; diphosphate metabolic process; and forebrain development. Acts upstream of or within several processes, in cluding ear development; positive regulation of cell population proliferation; and regulation of animal organ morphogenesis. Located in plasma membrane. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study Pfeiffer syndrome; atopic dermatitis; and otitis media. Human ortholog(s) of this gene implicated in several diseases, including Jackson-Weiss syndrome; bone disease (multiple); carcinoma (multiple); hematologic cancer (multiple); and hypogonadotropic hypogonadism (multiple). Orthologous to human FGFR1 (fibroblast growth factor receptor 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 26008808 | 26067819 | Mouse | 985 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8760138 | Fgfr1 | fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); fibroblast growth factor binding (ortholog); fibroblast growth factor receptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PA RTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); acute myeloid leukemia (ortholog); FOUND IN glutamatergic synapse (ortholog); perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog) | NW_004955463 | 14013247 | 14064354 | Chinchilla | 266 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12019925 | FGFR1 | fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); protein-containing complex binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); acute myeloid leukemia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | 8 | 37713133 | 37773098 | Bonobo | 295 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12303474 | FGFR1 | fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); protein-containing complex binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); acute myeloid leukemia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | 16 | 27029902 | 27080514 | Dog | 291 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12495788 | Fgfr1 | fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); protein-containing complex binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); acute myeloid leukemia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | NW_004936710 | 1760365 | 1815269 | Squirrel | 295 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13891245 | FGFR1 | fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); protein-containing complex binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); acute myeloid leukemia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); INTERACTS WITH deoxynivalenol; progesterone | | | | Pig | 295 | symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18387660 | FGFR1 | fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); protein-containing complex binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); acute myeloid leukemia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | | | | Green Monkey | 293 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18906399 | Fgfr1 | fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PARTICIPATES IN ce rium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); acute myeloid leukemia (ortholog); FOUND IN glutamatergic synapse (ortholog); perinuclear region of cytoplasm (ortholog); postsynapse (ortholog) | | | | Naked Mole-Rat | 289 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246188 | fgfr1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625927127 | Fgfr1 | fibroblast growth factor receptor 1 | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); fibroblast growth factor binding (ortholog); fibroblast growth factor receptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); auditory receptor cell development (ortholog); blood vessel morphogenesis (ortholog); PA RTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; ASSOCIATED WITH acoustic neuroma (ortholog); acrocephalosyndactylia (ortholog); acute myeloid leukemia (ortholog); FOUND IN glutamatergic synapse (ortholog); perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog) | | | | Black Rat | 265 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241561 | fgfr1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155244416 | fgfr1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 407429864 | fgfr1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 407429925 | fgfr1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 407429957 | fgfr1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 407429975 | fgfr1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1564070 | Fgfr1-ps1 | fibroblast growth factor receptor 1, pseudogene 1 | INTERACTS WITH ammonium chloride; bisphenol A; Cuprizon | 4 | 78610517 | 78612935 | Rat | 3 | symbol , PhenoGen , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1303233 | Fgfr1op2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 4 | 181222298 | 181243318 | Rat | 88 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1332316 | Fgfr1op2 | FGFR1 oncogene partner 2 | Enables identical protein binding activity. Acts upstream of or within wound healing. Predicted to be located in cytoplasm. Is expressed in thymus primordium. Orthologous to human FGFR1OP2 (FGFR1 oncogene partner 2). [provid ed by Alliance of Genome Resources, Jul 2025] | 6 | 146479401 | 146500696 | Mouse | 104 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1348205 | FGFR1OP2 | FGFR1 oncogene partner 2 | Predicted to enable identical protein binding activity. Predicted to be involved in response to wounding. Predicted to act upstream of or within wound healing. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Jul 2025] | 12 | 26938470 | 26966648 | Human | 87 | symbol , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 9010852 | Fgfr1op2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm (ortholog) | NW_004955413 | 21814133 | 21843105 | Chinchilla | 6 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12029928 | FGFR1OP2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm (inferred) | 12 | 59345834 | 59372895 | Bonobo | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12410502 | FGFR1OP2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm (inferred) | 27 | 20672166 | 20704530 | Dog | 7 | symbol , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12666414 | Fgfr1op2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm (inferred) | NW_004936548 | 521418 | 548290 | Squirrel | 7 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14038279 | FGFR1OP2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm (inferred) | | | | Pig | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18665483 | FGFR1OP2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm (inferred) | | | | Green Monkey | 7 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18914813 | Fgfr1op2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm (inferred) | | | | Naked Mole-Rat | 7 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 625866878 | Fgfr1op2 | FGFR1 oncogene partner 2 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN wound healing (ortholog); ASSOCIATED WITH myeloid neoplasm (ortholog); FOUND IN cytoplasm (ortholog) | | | | Black Rat | 6 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 8952804 | LOC102015062 | FGFR1 oncogene partner-like | | NW_004955446 | 16579166 | 16585757 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 12537087 | LOC101960774 | FGFR1 oncogene partner 2-like | | NW_004936516 | 7024890 | 7041498 | Squirrel | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 18903404 | LOC101701055 | FGFR1 oncogene partner 2 homolog | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 12533669 | LOC101971947 | FGFR1 oncogene partner 2 homolog | | NW_004936680 | 2655427 | 2656041 | Squirrel | | name | gene, pseudo, MODEL [RefSeq] |
| 18402033 | LOC103238271 | FGFR1 oncogene partner 2 homolog | | | | | Green Monkey | | name | gene, pseudo, MODEL [RefSeq] |
| 625920695 | LOC116906193 | FGFR1 oncogene partner 2 homolog | | | | | Black Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 329331285 | LOC129393509 | FGFR1 oncogene partner 2 homolog | | | | | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 38657666 | LOC100335030 | FGFR1 oncogene partner 2 pseudogene | | 12 | 49389174 | 49392335 | Human | | name | gene, pseudo, PROVISIONAL [RefSeq] |
| 18929970 | LOC101699959 | FGFR1 oncogene partner 2 pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 6481452 | FGFR1OP2P1 | FGFR1 oncogene partner 2 pseudogene 1 | | 13 | 26905488 | 26905776 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16560875 | AC087894.1 | fibroblast growth factor receptor 1 (FGFR1) | | 12 | 127876999 | 127877516 | Human | | old_gene_name , name | gene, pseudo, INFERRED [RefSeq] |
| 8937019 | LOC102013939 | FGFR1 oncogene partner 2 homolog pseudogene | | NW_004955486 | 342946 | 343511 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 16561486 | AC125611.2 | FGFR1 oncogene partner 2 (FGFR1OP2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1313011 | CEP43 | centrosomal protein 43 | This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been fo und in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013] | 6 | 166999397 | 167052718 | Human | 82 | old_gene_name , description , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1558504 | Cep43 | centrosomal protein 43 | Predicted to enable protein homodimerization activity; protein kinase binding activity; and protein tyrosine kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of protein kinase activity; positive regulation of cell growth; and positive regulation of cell migration. Predicted to be located in centriole; nucleus; and perinuclear region of cytoplasm. Predicted to be active in centrosome. Is expressed in several structures, including intestine; lung; renal tubule; spinal ganglion; and vibrissa follicle. Orthologous to human CEP43 (centrosomal protein 43). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 8383976 | 8415309 | Mouse | 99 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1583370 | Cep43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); protein kinase binding (ortholog); protein tyrosine kinase inhibitor activity (ortholog); INVOLVED IN negative regulation of protein kinase activity (ortholog); positive regulation of cell growth (ortholog); positive regul ation of cell migration (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH (+)-schisandrin B; alpha-Zearalanol; glyphosate | 1 | 55080983 | 55111509 | Rat | 86 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8830979 | Cep43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); protein kinase binding (ortholog); protein tyrosine kinase inhibitor activity (ortholog); INVOLVED IN negative regulation of protein kinase activity (ortholog); positive regulation of cell growth (ortholog); positive regul ation of cell migration (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog) | NW_004955439 | 15029485 | 15059076 | Chinchilla | 21 | old_gene_name , ensembl_full_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11786451 | CEP43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); protein tyrosine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); FOUND IN centriole (inferred); centrosome (inferred); ciliary basal body (inferred) | 6 | 164969391 | 165011935 | Bonobo | 26 | ensembl_gene_symbol , old_gene_name , ensembl_full_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12395694 | CEP43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); protein tyrosine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); FOUND IN centriole (inferred); centrosome (inferred); ciliary basal body (inferred) | 1 | 54853159 | 54877492 | Dog | 26 | ensembl_gene_symbol , old_gene_name , ensembl_full_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12555265 | Cep43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); protein tyrosine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); FOUND IN centriole (inferred); centrosome (inferred); ciliary basal body (inferred) | NW_004936489 | 16591959 | 16629703 | Squirrel | 26 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14056690 | CEP43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); protein tyrosine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); FOUND IN centriole (inferred); centrosome (inferred); ciliary basal body (inferred) | | | | Pig | 26 | ensembl_gene_symbol , old_gene_name , ensembl_full_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18524773 | CEP43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (inferred); protein kinase binding (inferred); protein tyrosine kinase inhibitor activity (inferred); INVOLVED IN negative regulation of protein kinase activity (ortholog); FOUND IN centriole (inferred); centrosome (inferred); ciliary basal body (inferred) | | | | Green Monkey | 26 | ensembl_gene_symbol , old_gene_name , ensembl_full_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909298 | Cep43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); protein kinase binding (ortholog); protein tyrosine kinase inhibitor activity (ortholog); INVOLVED IN negative regulation of protein kinase activity (ortholog); positive regulation of cell growth (ortholog); positive regul ation of cell migration (ortholog); FOUND IN centriole (ortholog); ciliary basal body (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 25 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 626100480 | Cep43 | centrosomal protein 43 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); protein kinase binding (ortholog); protein tyrosine kinase inhibitor activity (ortholog); INVOLVED IN negative regulation of protein kinase activity (ortholog); positive regulation of cell growth (ortholog); positive regul ation of cell migration (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog) | | | | Black Rat | 21 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1317506 | BCR | BCR activator of RhoGEF and GTPase | A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is e ncoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The unregulated tyrosine kinase activity of BCR-ABL1 contributes to the immortality of leukaemic cells. The BCR protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac and other kinases. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2020] | 22 | 23180509 | 23318037 | Human | 297 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 155238921 | fgfr1op2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 15039236 | FGFR1IIIC | FGF receptor | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); FOUND IN membrane (inferred) | | | | Pig | 7 | symbol | gene, protein-coding |
| 155238922 | fgfr1op2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155255833 | fgfr1op2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1603862 | CNPY1 | canopy FGF signaling regulator 1 | Cnpy1 is expressed in the midbrain-hindbrain (MHB) boundary in zebrafish, binds FGFR1 (MIM 136350), and plays a role in FGF signaling (Hirate and Okamoto, 2006 [PubMed 16488878]).[supplied by OMIM, Dec 2008] | 7 | 155501129 | 155546559 | Human | 41 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1342908 | TACC1 | transforming acidic coiled-coil containing protein 1 | This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq , Jun 2017] | 8 | 38728582 | 38853028 | Human | 165 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1317868 | ZMYM2 | zinc finger MYM-type containing 2 | The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results i n a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010] | 13 | 19863840 | 20089115 | Human | 184 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 8784756 | Cep20 | centrosomal protein 20 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cilium assembly (ortholog); ASSOCIATED WITH Familial Thoracic Aortic Aneurysm 4 (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); ciliary basal body (ortholog) | NW_004955442 | 650033 | 665540 | Chinchilla | 8 | old_gene_name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 12380097 | CEP20 | centrosomal protein 20 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); microtubule anchoring (inferred); ASSOCIATED WITH Familial Thoracic Aortic Aneurysm 4 (ortholog); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | 6 | 28016253 | 28035117 | Dog | 19 | old_gene_name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 14000240 | CEP20 | centrosomal protein 20 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); microtubule anchoring (inferred); ASSOCIATED WITH Familial Thoracic Aortic Aneurysm 4 (ortholog); FOUND IN motile cilium (ortholog); INTERACTS WITH d eoxynivalenol | | | | Pig | 19 | old_gene_name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 18565004 | CEP20 | centrosomal protein 20 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); microtubule anchoring (inferred); ASSOCIATED WITH Familial Thoracic Aortic Aneurysm 4 (ortholog); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | | | | Green Monkey | 18 | old_gene_name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 1305823 | Cep20 | centrosomal protein 20 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cilium assembly (ortholog); ASSOCIATED WITH Familial Thoracic Aortic Aneurysm 4 (ortholog); FOUND IN centriolar satellite (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH acetamide; bisp henol A; buspirone | 10 | 1221294 | 1243144 | Rat | 66 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1314088 | Cep20 | centrosomal protein 20 | Predicted to enable identical protein binding activity. Predicted to be involved in cilium assembly. Located in ciliary basal body and motile cilium. Is expressed in several structures, including central nervous system; heart; liver; lung; and spleen. Orthologous to human CEP20 (centrosomal protein 20). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 14117105 | 14136093 | Mouse | 93 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1606173 | CEP20 | centrosomal protein 20 | Enables identical protein binding activity. Involved in cilium assembly. Located in centriolar satellite; ciliary basal body; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 15865719 | 15888603 | Human | 69 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12708586 | Cep20 | centrosomal protein 20 | ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); microtubule anchoring (inferred); ASSOCIATED WITH Familial Thoracic Aortic Aneurysm 4 (ortholog); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | NW_004936501 | 3320671 | 3333705 | Squirrel | 18 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18928034 | Cep20 | centrosomal protein 20 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); microtubule anchoring (inferred); ASSOCIATED WITH Familial Thoracic Aortic Aneurysm 4 (ortholog); FOUND IN centriolar satellite (inferred); centriole (inferred); centrosome (inferred) | | | | Naked Mole-Rat | 13 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 329332511 | LOC129394161 | uncharacterized LOC129394161 | | | | | Bonobo | | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
