| 71069 | Fcgr2a | Fc gamma receptor 2A | ENCODES a protein that exhibits immunoglobulin receptor binding; IgG binding (ortholog); IgG receptor activity (ortholog); INVOLVED IN nerve development; regulation of antibody-dependent cellular cytotoxicity; regulation of Fc receptor mediated stimulatory signaling pathway; PARTICIPATES IN Fc gamma receptor mediated signaling pathway; Leishmaniasis pathway; phagocytosis pathway; ASSOCIATED WITH Acute Lung Injury; crescentic glomerulonephritis; Wallerian Degeneration; FOUND IN cell surface; external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol | 13 | 85813516 | 85830269 | Rat | 285 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1316933 | FCGR2A | Fc gamma receptor IIa | This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis a nd clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008] | 1 | 161505457 | 161524048 | Human | 265 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 12450753 | Fcgr2a | Fc fragment of IgG receptor IIa | ENCODES a protein that exhibits immunoglobulin receptor binding (ortholog); INVOLVED IN nerve development (ortholog); regulation of antibody-dependent cellular cytotoxicity (ortholog); regulation of Fc receptor mediated stimulatory signaling pathway (ortholog); ASSOCIATED WITH Acute Lung Injury (ort holog); Anaphylaxis (ortholog); arthus reaction (ortholog); FOUND IN cell surface (ortholog) | NW_004937131 | 15542 | 22099 | Squirrel | 94 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18486285 | FCGR2A | Fc gamma receptor IIa | ENCODES a protein that exhibits immunoglobulin receptor binding (ortholog); INVOLVED IN nerve development (ortholog); regulation of antibody-dependent cellular cytotoxicity (ortholog); regulation of Fc receptor mediated stimulatory signaling pathway (ortholog); ASSOCIATED WITH Acute Lung Injury (ort holog); Anaphylaxis (ortholog); arthus reaction (ortholog); FOUND IN cell surface (ortholog) | | | | Green Monkey | 95 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625946904 | Fcgr2a | Fc fragment of IgG receptor IIa | ENCODES a protein that exhibits immunoglobulin receptor binding (ortholog); INVOLVED IN nerve development (ortholog); regulation of antibody-dependent cellular cytotoxicity (ortholog); regulation of Fc receptor mediated stimulatory signaling pathway (ortholog); ASSOCIATED WITH Acute Lung Injury (ort holog); Anaphylaxis (ortholog); arthus reaction (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog) | | | | Black Rat | 81 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18915022 | Fcgr2a | Fc fragment of IgG receptor IIa | ENCODES a protein that exhibits immunoglobulin receptor binding (ortholog); INVOLVED IN nerve development (ortholog); regulation of antibody-dependent cellular cytotoxicity (ortholog); regulation of Fc receptor mediated stimulatory signaling pathway (ortholog); ASSOCIATED WITH Acute Lung Injury (ort holog); Anaphylaxis (ortholog); arthus reaction (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 81 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 9127992 | Fcgr2a-ps1 | Fc gamma receptor 2A, pseudogene 1 | ENCODES a pseudogene that exhibits IgG binding (inferred); INVOLVED IN regulation of immune system process (inferred); FOUND IN plasma membrane (inferred) | 13 | 85855437 | 85868827 | Rat | 3 | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1332447 | Fcgr2b | Fc receptor, IgG, low affinity IIb | Enables IgG binding activity. Involved in several processes, including Fc receptor-mediated immune complex endocytosis; nervous system development; and regulation of response to endoplasmic reticulum stress. Acts upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; negative regulation of immune effector process; and regulation of phagocytosis. Located in cell body; dendritic spine; and external side of plasma membrane. Is expressed in several structures, including adipose tissue; bone; liver; lung; and spleen. Used to study malaria and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to several human genes including FCGR2A (Fc gamma receptor IIa) and FCGR2B (Fc gamma receptor IIb). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 170786186 | 170804141 | Mouse | 345 | description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11876799 | LOC100991644 | low affinity immunoglobulin gamma Fc region receptor II-a | ENCODES a protein that exhibits immunoglobulin receptor binding (ortholog); INVOLVED IN nerve development (ortholog); regulation of antibody-dependent cellular cytotoxicity (ortholog); regulation of Fc receptor mediated stimulatory signaling pathway (ortholog); ASSOCIATED WITH Acute Lung Injury (ort holog); Anaphylaxis (ortholog); arthus reaction (ortholog); FOUND IN cell surface (ortholog) | 1 | 136892311 | 136906450 | Bonobo | 93 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 16568487 | AP001318.3 | Fc fragment of IgG, low affinity IIa, receptor (CD32) (FCGR2A) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16566706 | AL590385.2 | novel transcript, readthrough between FCGR2A and FCGR2C polymormphic pseudogene | | | | | Human | | name | gene, lncrna |
| 1594388 | Fcgr2al1 | Fc gamma receptor 2A like 1 | ENCODES a protein that exhibits IgG binding (inferred); INVOLVED IN regulation of immune system process (inferred); FOUND IN plasma membrane (inferred) | 13 | 85835616 | 85846011 | Rat | 3 | symbol , ensembl_gene_symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 736451 | Fcgr3 | Fc receptor, IgG, low affinity III | Enables IgG binding activity and IgG receptor activity. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; phagocytosis; and positive regulation of hypersensitivity. Located in external side of plasma membrane. Is expressed in liver and spleen. Human or tholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc gamma receptor IIa). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 170878738 | 170893477 | Mouse | 260 | description | gene, protein-coding, VALIDATED [RefSeq] |
