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Pathways
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31 records found for search term Dars
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
14372115dars-1Roundwormsymbolgene, null
14372118dars-2Roundwormsymbolgene, null
621167Dars1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aspartate-tRNA ligase activity (ortholog); INVOLVED IN aspartyl-tRNA aminoacylation (ortholog); PARTICIPATES IN Canavan disease pathway; aminoacyl-tRNA biosynthetic pathway; ASSOCIATED WITH genetic disease (ortholog); Hypomyelination with Brainstem and Spinal Cord Inv134241035142465467Rat151symbol , PhenoGen , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
732389DARS1aspartyl-tRNA synthetase 1This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involv2135905881135985684Human177symbol , ensembl_gene_symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
732390Dars1aspartyl-tRNA synthetase 1Predicted to enable RNA binding activity and aspartate-tRNA ligase activity. Predicted to be involved in aspartyl-tRNA aminoacylation. Located in cytoplasm and synapse. Part of aminoacyl-tRNA synthetase multienzyme complex. Is expressed in several structures, including alimentary system; brain; geni1128291444128345153Mouse139symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
8963310Dars1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aspartate-tRNA ligase activity (ortholog); INVOLVED IN aspartyl-tRNA aminoacylation (ortholog); PARTICIPATES IN Canavan disease pathway; ASSOCIATED WITH genetic disease (ortholog); Hypomyelination with Brainstem and Spinal Cord Involvement and Leg Spasticity (orthologNW_00495544032686483345808Chinchilla16symbol , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
11784673DARS1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); translation (inferred); tRNA aminoacylation for protein translation (inferred); PARTICIPATES IN Canavan d2B2387693123956032Bonobo36symbol , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
12285736DARS1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); translation (inferred); tRNA aminoacylation for protein translation (inferred); PARTICIPATES IN Canavan d193869017038751360Dog36symbol , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
12564933Dars1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); translation (inferred); tRNA aminoacylation for protein translation (inferred); PARTICIPATES IN Canavan dNW_0049364693992118239979297Squirrel36symbol , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
14002530DARS1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); translation (inferred); tRNA aminoacylation for protein translation (inferred); PARTICIPATES IN Canavan dPig38symbol , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
18767189DARS1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); translation (inferred); tRNA aminoacylation for protein translation (inferred); PARTICIPATES IN Canavan dGreen Monkey36symbol , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
18923554Dars1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); translation (inferred); tRNA aminoacylation for protein translation (inferred); PARTICIPATES IN Canavan dNaked Mole-Rat31symbol , old_gene_symbolgene, protein-coding, MODEL [RefSeq]
8695150DARS1-AS1DARS1 antisense RNA 1INTERACTS WITH acrylamide; arsenite(3-); okadaic acid2135985176136007542Human4symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbolgene, ncrna, VALIDATED [RefSeq]
155249769dars1Tropical Clawed Frogsymbolgene, null
625958340Dars1aspartyl-tRNA synthetase 1ENCODES a protein that exhibits aspartate-tRNA ligase activity (ortholog); INVOLVED IN aspartyl-tRNA aminoacylation (ortholog); PARTICIPATES IN Canavan disease pathway; ASSOCIATED WITH genetic disease (ortholog); Hypomyelination with Brainstem and Spinal Cord Involvement and Leg Spasticity (orthologBlack Rat16symbolgene, protein-coding, MODEL [RefSeq]
1308286Dars2aspartyl-tRNA synthetase 2 (mitochondrial)ENCODES a protein that exhibits aspartate-tRNA ligase activity (ortholog); aspartate-tRNA(Asn) ligase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial asparaginyl-tRNA aminoacylation (ortholog); tRNA aminoacylation (ortholog); PARTICIPATES IN aminoacyl-tRN137584207875870319Rat123symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1550719Dars2aspartyl-tRNA synthetase 2 (mitochondrial)Predicted to enable aspartate-tRNA ligase activity; aspartate-tRNA(Asn) ligase activity; and protein homodimerization activity. Predicted to be involved in aspartyl-tRNA aminoacylation and mitochondrial asparaginyl-tRNA aminoacylation. Located in mitochondrion. Is expressed in several structures, in1160868171160898236Mouse130symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1605663DARS2aspartyl-tRNA synthetase 2, mitochondrialThe protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL1173824673173858546Human238symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8868683Dars2aspartyl-tRNA synthetase 2, mitochondrialENCODES a protein that exhibits aspartate-tRNA ligase activity (ortholog); aspartate-tRNA(Asn) ligase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial asparaginyl-tRNA aminoacylation (ortholog); tRNA aminoacylation (ortholog); ASSOCIATED WITH cerebellar atNW_0049554061396408713991691Chinchilla26symbolgene, protein-coding, MODEL [RefSeq]
11711456DARS2aspartyl-tRNA synthetase 2, mitochondrialENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); aspartate-tRNA(Asn) ligase activity (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); mitochondrial asparaginyl-tRNA aminoacylation (inferred); translation (inferred);1149342301149375979Bonobo44symbolgene, protein-coding, MODEL [RefSeq]
12115466DARS2aspartyl-tRNA synthetase 2, mitochondrialENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); aspartate-tRNA(Asn) ligase activity (inferred); INVOLVED IN lysyl-tRNA aminoacylation (inferred); mitochondrial asparaginyl-tRNA aminoacylation (inferred); translation (inferred); AS72537870525406975Dog46symbolgene, protein-coding, MODEL [RefSeq]
12618348Dars2aspartyl-tRNA synthetase 2, mitochondrialENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); aspartate-tRNA(Asn) ligase activity (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); mitochondrial asparaginyl-tRNA aminoacylation (inferred); translation (inferred);NW_0049364811402947814052724Squirrel44symbolgene, protein-coding, MODEL [RefSeq]
14029055DARS2aspartyl-tRNA synthetase 2, mitochondrialENCODES a protein that exhibits aspartate-tRNA ligase activity (ortholog); aspartate-tRNA(Asn) ligase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial asparaginyl-tRNA aminoacylation (ortholog); tRNA aminoacylation (ortholog); ASSOCIATED WITH cerebellar atPig40symbolgene, protein-coding, MODEL [RefSeq]
18636421DARS2aspartyl-tRNA synthetase 2, mitochondrialENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); aspartate-tRNA(Asn) ligase activity (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); mitochondrial asparaginyl-tRNA aminoacylation (inferred); translation (inferred);Green Monkey44symbolgene, protein-coding, MODEL [RefSeq]
18918314Dars2aspartyl-tRNA synthetase 2, mitochondrialENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); aspartate-tRNA ligase activity (inferred); aspartate-tRNA(Asn) ligase activity (inferred); INVOLVED IN aspartyl-tRNA aminoacylation (inferred); mitochondrial asparaginyl-tRNA aminoacylation (inferred); translation (inferred);Naked Mole-Rat44symbolgene, protein-coding, MODEL [RefSeq]
155258161dars2Tropical Clawed Frogsymbolgene, null
625850590Dars2aspartyl-tRNA synthetase 2, mitochondrialENCODES a protein that exhibits aspartate-tRNA ligase activity (ortholog); aspartate-tRNA(Asn) ligase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial asparaginyl-tRNA aminoacylation (ortholog); tRNA aminoacylation (ortholog); ASSOCIATED WITH cerebellar atBlack Rat26symbolgene, protein-coding, MODEL [RefSeq]
155249770dars1.LAfrican Clawed Frogsymbolgene, null
155251823dars1.SAfrican Clawed Frogsymbolgene, null
155238936dars2.LAfrican Clawed Frogsymbolgene, null
1593553Dars1-ps1aspartyl-tRNA synthetase 1, pseudogene 181279606912814990Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]