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Gene: Dars (aspartyl-tRNA synthetase) Mus musculus
Symbol: Dars
Name: aspartyl-tRNA synthetase
Description: Predicted to have RNA binding activity and aspartate-tRNA ligase activity. Predicted to be involved in aspartyl-tRNA aminoacylation. Localizes to the aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; and synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human DARS1 (aspartyl-tRNA synthetase 1); PARTICIPATES IN Canavan disease pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730439G15Rik; aspartate--tRNA ligase; aspartate--tRNA ligase, cytoplasmic; aspartyl-tRNA synthetase, cytoplasmic; aspRS
Homo sapiens (human) : DARS1 (aspartyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dars (aspartyl-tRNA synthetase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dars1 (aspartyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DARS1 (aspartyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : DARS1 (aspartyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dars1 (aspartyl-tRNA synthetase 1)
Sus scrofa (pig) : DARS1 (aspartyl-tRNA synthetase 1)
Chlorocebus sabaeus (green monkey) : DARS1 (aspartyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Dars1 (aspartyl-tRNA synthetase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1128,363,707 - 128,417,368 (-)Ensembl
GRCm381128,363,707 - 128,417,416 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371130,260,284 - 130,313,993 (-)NCBIGRCm37mm9NCBIm37
MGSCv361130,191,253 - 130,244,884 (-)NCBImm8
Celera1130,992,060 - 131,045,578 (-)NCBICelera
Cytogenetic Map1 E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dars
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732390
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.