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Gene: Dars (aspartyl-tRNA synthetase) Mus musculus
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Symbol: Dars
Name: aspartyl-tRNA synthetase
Description: Predicted to have RNA binding activity and aspartate-tRNA ligase activity. Predicted to be involved in aspartyl-tRNA aminoacylation. Localizes to the aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; and synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human DARS1 (aspartyl-tRNA synthetase 1); PARTICIPATES IN Canavan disease pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730439G15Rik; aspartate--tRNA ligase; aspartate--tRNA ligase, cytoplasmic; aspartyl-tRNA synthetase, cytoplasmic; aspRS
Orthologs:
Homo sapiens (human) : DARS1 (aspartyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dars (aspartyl-tRNA synthetase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dars1 (aspartyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DARS1 (aspartyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : DARS1 (aspartyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dars1 (aspartyl-tRNA synthetase 1)
Sus scrofa (pig) : DARS1 (aspartyl-tRNA synthetase 1)
Chlorocebus sabaeus (green monkey) : DARS1 (aspartyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Dars1 (aspartyl-tRNA synthetase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1128,363,707 - 128,417,368 (-)Ensembl
GRCm381128,363,707 - 128,417,416 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371130,260,284 - 130,313,993 (-)NCBIGRCm37mm9NCBIm37
MGSCv361130,191,253 - 130,244,884 (-)NCBImm8
Celera1130,992,060 - 131,045,578 (-)NCBICelera
Cytogenetic Map1 E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dars
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732390
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.