Dars2 (aspartyl-tRNA synthetase 2, mitochondrial) - Rat Genome Database

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Gene: Dars2 (aspartyl-tRNA synthetase 2, mitochondrial) Chinchilla lanigera
Analyze
Symbol: Dars2
Name: aspartyl-tRNA synthetase 2, mitochondrial
RGD ID: 8868683
Description: ENCODES a protein that exhibits aspartate-tRNA ligase activity (ortholog); aspartate-tRNA(Asn) ligase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial asparaginyl-tRNA aminoacylation (ortholog); tRNA aminoacylation (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); antithrombin III deficiency (ortholog); autoimmune lymphoproliferative syndrome (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrial membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aspartate--tRNA ligase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540613,964,087 - 13,991,691 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540613,964,087 - 13,991,691 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dars2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540613,964,087 - 13,991,691 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540613,964,087 - 13,991,691 (+)NCBIChiLan1.0ChiLan1.0
DARS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381173,824,673 - 173,858,546 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1173,824,653 - 173,858,808 (+)EnsemblGRCh38hg38GRCh38
GRCh371173,793,811 - 173,827,684 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361172,060,581 - 172,094,305 (+)NCBINCBI36Build 36hg18NCBI36
Celera1146,903,269 - 146,937,151 (+)NCBICelera
Cytogenetic Map1q25.1NCBI
HuRef1145,018,544 - 145,052,684 (+)NCBIHuRef
CHM1_11175,216,240 - 175,250,123 (+)NCBICHM1_1
T2T-CHM13v2.01173,182,837 - 173,216,665 (+)NCBIT2T-CHM13v2.0
Dars2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,868,171 - 160,898,236 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,868,171 - 160,898,228 (-)EnsemblGRCm39 Ensembl
GRCm381161,037,580 - 161,070,668 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,040,601 - 161,070,658 (-)EnsemblGRCm38mm10GRCm38
MGSCv371162,970,744 - 163,000,763 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361162,878,252 - 162,907,326 (-)NCBIMGSCv36mm8
Celera1163,482,244 - 163,511,984 (-)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map169.75NCBI
Dars2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81375,842,078 - 75,870,319 (-)NCBIGRCr8
mRatBN7.21373,308,726 - 73,336,558 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1373,308,726 - 73,336,934 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1375,901,324 - 75,929,075 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01377,185,768 - 77,213,250 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01374,445,315 - 74,473,146 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01378,857,638 - 78,885,464 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1378,857,638 - 78,885,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01383,752,703 - 83,780,466 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41376,599,896 - 76,628,866 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11376,614,300 - 76,643,058 (-)NCBI
Celera1373,097,042 - 73,124,760 (-)NCBICelera
Cytogenetic Map13q22NCBI
DARS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2175,865,791 - 75,901,415 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1175,539,824 - 75,579,475 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01149,342,301 - 149,375,979 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11153,045,886 - 153,080,461 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1153,045,886 - 153,080,461 (+)Ensemblpanpan1.1panPan2
DARS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1725,378,705 - 25,406,975 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl725,378,705 - 25,406,947 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha724,911,148 - 24,939,939 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0725,129,295 - 25,158,108 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl725,129,462 - 25,158,083 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1725,048,689 - 25,077,453 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0725,131,016 - 25,159,791 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0725,275,653 - 25,304,718 (-)NCBIUU_Cfam_GSD_1.0
Dars2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934496,181,367 - 96,205,944 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648114,027,772 - 14,052,806 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648114,029,478 - 14,052,724 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DARS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9116,109,986 - 116,140,627 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19116,109,970 - 116,140,635 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29127,744,570 - 127,775,320 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DARS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12555,334,669 - 55,367,257 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2555,332,340 - 55,367,248 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605556,895,818 - 56,929,158 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dars2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247718,003,295 - 8,034,043 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247718,003,208 - 8,033,981 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000012147   ⟹   ENSCLAP00000012006
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540613,964,087 - 13,991,691 (+)Ensembl
RefSeq Acc Id: XM_005374874   ⟹   XP_005374931
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540613,964,087 - 13,991,691 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005374931 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000012006
  ENSCLAP00000012006.1
Reference Protein Sequences
RefSeq Acc Id: XP_005374931   ⟸   XM_005374874
- UniProtKB: A0A8C2VF36 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000012006   ⟸   ENSCLAT00000012147
Protein Domains
Aminoacyl-transfer RNA synthetases class-II family


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008286 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000012147 ENTREZGENE
  ENSCLAT00000012147.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
  3.30.1360.30 UniProtKB/TrEMBL
InterPro Aa-tRNA-synt_II UniProtKB/TrEMBL
  aa-tRNA-synth_II UniProtKB/TrEMBL
  aa-tRNA-synth_II/BPL/LPL UniProtKB/TrEMBL
  Asp-tRNA-ligase_1 UniProtKB/TrEMBL
  Asp-tRNA-ligase_1_N UniProtKB/TrEMBL
  Asp/Asn-tRNA-synth_IIb UniProtKB/TrEMBL
  AspRS_core UniProtKB/TrEMBL
  GAD-like_sf UniProtKB/TrEMBL
  GAD_dom UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  NA-bd_OB_tRNA UniProtKB/TrEMBL
NCBI Gene Dars2 ENTREZGENE
PANTHER ASPARTYL/LYSYL-TRNA SYNTHETASE UniProtKB/TrEMBL
  PTHR22594:SF5 UniProtKB/TrEMBL
Pfam GAD UniProtKB/TrEMBL
  tRNA-synt_2 UniProtKB/TrEMBL
  tRNA_anti-codon UniProtKB/TrEMBL
PRINTS TRNASYNTHASP UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_II UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/TrEMBL
  SSF55261 UniProtKB/TrEMBL
  SSF55681 UniProtKB/TrEMBL
UniProt A0A8C2VF36 ENTREZGENE, UniProtKB/TrEMBL