| 2463 | Cyp2a1 | cytochrome P450, family 2, subfamily a, polypeptide 1 | ENCODES a protein that exhibits oxidoreductase activity; steroid hydroxylase activity; heme binding (ortholog); INVOLVED IN coumarin metabolic process; PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; vitamin A deficiency pathway; caffeine metabolic pathway; ASSOCIATED WITH aut ism spectrum disorder (ortholog); Diamond-Blackfan anemia (ortholog); lung adenocarcinoma (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (+)-schisandrin B; (S)-nicotine; 1,3,5-trinitro-1,3,5-triazinane | 1 | 91359278 | 91372554 | Rat | 251 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1332108 | Cyp2a12 | cytochrome P450, family 2, subfamily a, polypeptide 12 | Predicted to enable heme binding activity and monooxygenase activity. Predicted to be involved in coumarin metabolic process; epoxygenase P450 pathway; and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular m embrane-bounded organelle. Is expressed in liver. Orthologous to human CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 26728515 | 26736243 | Mouse | 62 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1352512 | CYP2A13 | cytochrome P450 family 2 subfamily A member 13 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although i ts endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008] | 19 | 41088451 | 41096195 | Human | 235 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 11901163 | CYP2A13 | cytochrome P450 family 2 subfamily A member 13 | ENCODES a protein that exhibits arachidonate epoxygenase activity (inferred); heme binding (inferred); iron ion binding (inferred); INVOLVED IN coumarin metabolic process (inferred); epoxygenase P450 pathway (inferred); organic acid metabolic process (inferred); FOUND IN cytoplasm (inferred); endopl asmic reticulum membrane (inferred) | 19 | 38099052 | 38106884 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12180515 | CYP2A13 | cytochrome P450 family 2 subfamily A polypeptide 13 | ENCODES a protein that exhibits oxidoreductase activity (ortholog); steroid hydroxylase activity (ortholog); INVOLVED IN cellular response to cadmium ion (ortholog); coumarin metabolic process (ortholog); heme metabolic process (ortholog); PARTICIPATES IN phase I biotransformation pathway via cytoch rome P450; retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Diamond-Blackfan anemia (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH clofibrate; phenobarbital | 1 | 112932246 | 112938248 | Dog | 36 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 14230852 | CYP2A19 | cytochrome P450 family 2 subfamily A member 19 | ENCODES a protein that exhibits oxidoreductase activity (ortholog); steroid hydroxylase activity (ortholog); INVOLVED IN coumarin metabolic process (ortholog); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED W ITH autism spectrum disorder (ortholog); Diamond-Blackfan anemia (ortholog); lung adenocarcinoma (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH cadmium atom; cadmium dichloride; coumarin | | | | Pig | 40 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 284205619 | cyp2a13l | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 2464 | Cyp2a2 | cytochrome P450, family 2, subfamily a, polypeptide 2 | ENCODES a protein that exhibits steroid hydroxylase activity; PARTICIPATES IN caffeine metabolic pathway; phase I biotransformation pathway via cytochrome P450; retinol metabolic pathway; ASSOCIATED WITH Experimental Liver Cirrhosis; FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 91391492 | 91417158 | Rat | 87 | ensembl_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2465 | Cyp2a3 | cytochrome P450, family 2, subfamily a, polypeptide 3 | ENCODES a protein that exhibits heme binding (inferred); iron ion binding (inferred); metal ion binding (inferred); INVOLVED IN response to stilbenoid (ortholog); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATE D WITH autism spectrum disorder (ortholog); Experimental Liver Neoplasms (ortholog); Lynch syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (S)-nicotine; 17beta-estradiol; 1H-pyrazole | 1 | 91299584 | 91307650 | Rat | 202 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18918998 | LOC101706775 | cytochrome P450 2A3 | ENCODES a protein that exhibits arachidonate epoxygenase activity (inferred); heme binding (inferred); iron ion binding (inferred); INVOLVED IN coumarin metabolic process (inferred); epoxygenase P450 pathway (inferred); organic acid metabolic process (inferred); FOUND IN cytoplasm (inferred); endopl asmic reticulum membrane (inferred) | | | | Naked Mole-Rat | 21 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1354364 | CYP2A7P1 | cytochrome P450 family 2 subfamily A member 7 pseudogene 1 | INTERACTS WITH aflatoxin B1; sodium arsenite | 19 | 41024251 | 41028263 | Human | 3 | old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1621331 | Cyp2a22 | cytochrome P450, family 2, subfamily a, polypeptide 22 | Predicted to enable heme binding activity and monooxygenase activity. Predicted to be involved in coumarin metabolic process; epoxygenase P450 pathway; and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Orthologous to human CYP2A1 ='font-weight:700;'>CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 26631564 | 26638838 | Mouse | 146 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1624100 | Cyp2a4 | cytochrome P450, family 2, subfamily a, polypeptide 4 | Predicted to enable enzyme binding activity; heme binding activity; and monooxygenase activity. Involved in response to stilbenoid. Predicted to be located in cytoplasmic microtubule. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in liver; lung; metan ephros; nervous system; and nose. Orthologous to several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13) and CYP2A6 (cytochrome P450 family 2 subfamily A member 6). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 26006617 | 26014513 | Mouse | 206 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 731867 | Cyp2a5 | cytochrome P450, family 2, subfamily a, polypeptide 5 | Predicted to enable enzyme binding activity; heme binding activity; and monooxygenase activity. Involved in response to stilbenoid. Acts upstream of or within cellular response to cadmium ion and heme metabolic process. Predicted to be located in cytoplasmic microtubule. Predicted to be active in cy toplasm and intracellular membrane-bounded organelle. Is expressed in alimentary system; liver; nervous system; nose; and respiratory system. Orthologous to several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13) and CYP2A6 (cytochrome P450 family 2 subfamily A member 6). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 26534764 | 26542689 | Mouse | 556 | description | gene, protein-coding, VALIDATED [RefSeq] |