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38 records found for search term Cth
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
2443Cthcystathionine gamma-lyaseENCODES a protein that exhibits cystathionine gamma-lyase activity (ortholog); identical protein binding (ortholog); L-cystine L-cysteine-lyase (deaminating) activity (ortholog); INVOLVED IN glutathione metabolic process; negative regulation of cell growth; negative regulation of cell population pro2249634731249661066Rat429symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
732084CTHcystathionine gamma-lyaseThis gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene17041126870439851Human482symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
732085Cthcystathionine gamma lyaseEnables L-cystine L-cysteine-lyase (deaminating) and cystathionine gamma-lyase activity. Involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of canonical NF-kappaB signal transduction; and protein sulfhydration. Acts upstream o3157599885157630718Mouse459symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9020582Cthcystathionine gamma-lyaseENCODES a protein that exhibits cystathionine gamma-lyase activity (ortholog); identical protein binding (ortholog); L-cystine L-cysteine-lyase (deaminating) activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glutathione metabolic process (ortholog); hydrogeNW_0049554232154258721567935Chinchilla56symbolgene, protein-coding, MODEL [RefSeq]
11898572CTHcystathionine gamma-lyaseENCODES a protein that exhibits carbon-sulfur lyase activity (inferred); cystathionine gamma-lyase activity (inferred); homocysteine desulfhydrase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glutathione metabolic process (ortholog); negative regulatio16964660869674301Bonobo65symbolgene, protein-coding, MODEL [RefSeq]
12146301CTHcystathionine gamma-lyaseENCODES a protein that exhibits identical protein binding (ortholog); L-cystine L-cysteine-lyase (deaminating) activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glutathione metabolic process (ortholog); hydrogen sulfide biosynthetic process (ortholog); PART67532432875348476Dog61symbolgene, protein-coding, MODEL [RefSeq]
12559995Cthcystathionine gamma-lyaseENCODES a protein that exhibits carbon-sulfur lyase activity (inferred); cystathionine gamma-lyase activity (inferred); homocysteine desulfhydrase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glutathione metabolic process (ortholog); negative regulatioNW_00493659116194461643667Squirrel65symbolgene, protein-coding, MODEL [RefSeq]
13954283CTHcystathionine gamma-lyaseENCODES a protein that exhibits cystathionine gamma-lyase activity (ortholog); L-cystine L-cysteine-lyase (deaminating) activity (ortholog); pyridoxal phosphate binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glutathione metabolic process (ortholog); hydroPig81symbolgene, protein-coding, VALIDATED [RefSeq]
18593769CTHcystathionine gamma-lyaseENCODES a protein that exhibits carbon-sulfur lyase activity (inferred); cystathionine gamma-lyase activity (inferred); homocysteine desulfhydrase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glutathione metabolic process (ortholog); negative regulatioGreen Monkey65symbolgene, protein-coding, MODEL [RefSeq]
18910186Cthcystathionine gamma-lyaseENCODES a protein that exhibits identical protein binding (ortholog); L-cystine L-cysteine-lyase (deaminating) activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glutathione metabolic process (ortholog); hydrogen sulfide biosynthetic process (ortholog); PARTNaked Mole-Rat63symbolgene, protein-coding, PROVISIONAL [RefSeq]
155242891cthTropical Clawed Frogsymbolgene, null
626087615Cthcystathionine gamma-lyaseENCODES a protein that exhibits cystathionine gamma-lyase activity (ortholog); identical protein binding (ortholog); L-cystine L-cysteine-lyase (deaminating) activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); glutathione metabolic process (ortholog); hydrogeBlack Rat56symbolgene, protein-coding, MODEL [RefSeq]
14375939cth-1Roundwormsymbolgene, null
14375940cth-2Roundwormsymbolgene, null
155242892cth.LAfrican Clawed Frogsymbolgene, null
155243330cth.SAfrican Clawed Frogsymbolgene, null
1344618VSIG2V-set and immunoglobulin domain containing 2Predicted to be involved in lipid metabolic process. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]11124747474124752255Human34old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
736055Cyth1cytohesin 1Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within establishment of epithelial cell polarity. Located in bicellular tight junction; cytoplasmic side of plasma membrane; and cytosol. Is expressed in nervous system. Orthologous to human CYTH1 (cytohesin 1). [provided by All11118054996118139452Mouse110old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
14375805CTH1Yeastsymbolgene, null
628801Cthrc1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (ortholog); Wnt-protein binding (ortholog); INVOLVED IN cell migration; cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASSOCIATED WIT77200737272017654Rat135symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1352911CTHRC1collagen triple helix repeat containing 1This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. 8103371538103382989Human139symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1550461Cthrc1collagen triple helix repeat containing 1Enables Wnt-protein binding activity and frizzled binding activity. Acts upstream of or within several processes, including establishment of planar polarity involved in neural tube closure; inner ear development; and negative regulation of canonical Wnt signaling pathway. Located in sarcoplasm. Is e153894032738950516Mouse170symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9045391Cthrc1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (ortholog); Wnt-protein binding (ortholog); INVOLVED IN cell migration (ortholog); cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASSNW_0049554172752042027525907Chinchilla19symbolgene, protein-coding, MODEL [RefSeq]
11752775CTHRC1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (inferred); Wnt-protein binding (inferred); INVOLVED IN cell migration (ortholog); cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASS8100027417100038945Bonobo19symbolgene, protein-coding, MODEL [RefSeq]
12179672CTHRC1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (inferred); Wnt-protein binding (inferred); INVOLVED IN cell migration (ortholog); cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASS1348010494811565Dog20symbolgene, protein-coding, MODEL [RefSeq]
12722344Cthrc1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (inferred); Wnt-protein binding (inferred); INVOLVED IN cell migration (ortholog); cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASSNW_0049364704038121540392105Squirrel19symbolgene, protein-coding, MODEL [RefSeq]
14100824CTHRC1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (inferred); Wnt-protein binding (inferred); INVOLVED IN cell migration (ortholog); cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASSPig24symbolgene, protein-coding, MODEL [RefSeq]
18634231CTHRC1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (inferred); Wnt-protein binding (inferred); INVOLVED IN cell migration (ortholog); cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASSGreen Monkey19symbolgene, protein-coding, MODEL [RefSeq]
18923367Cthrc1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (ortholog); Wnt-protein binding (ortholog); INVOLVED IN cell migration (ortholog); cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASSNaked Mole-Rat19symbolgene, protein-coding, MODEL [RefSeq]
155252207cthrc1Tropical Clawed Frogsymbolgene, null
626097668Cthrc1collagen triple helix repeat containing 1ENCODES a protein that exhibits frizzled binding (ortholog); Wnt-protein binding (ortholog); INVOLVED IN cell migration (ortholog); cochlea morphogenesis (ortholog); establishment of planar polarity involved in neural tube closure (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; ASSBlack Rat19symbolgene, protein-coding, MODEL [RefSeq]
155260033cthrc1.LAfrican Clawed Frogsymbolgene, null
155252444cthrc1.SAfrican Clawed Frogsymbolgene, null
10400005CTHRC1P1collagen triple helix repeat containing 1 pseudogene 1X7917720079177668Humansymbol , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
1603362NKX2-6NK2 homeobox 6This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related 82370174023706756Human156old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1317100TBX1T-box transcription factor 1This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. 221975670319783593Human644old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
737501PKMpyruvate kinase M1/2This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic157219902972231591Human475old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
7244483CDIPTOSPCDIP transferase opposite strand, pseudogeneENCODES a pseudogene that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); INTERACTS WITH 2-hydroxypropanoic acid; methylmercury chloride; propanal162986368329868053Human12old_gene_symbolgene, pseudo, VALIDATED [RefSeq]