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Gene: Cyth1 (cytohesin 1) Mus musculus
Symbol: Cyth1
Name: cytohesin 1
Description: Exhibits ARF guanyl-nucleotide exchange factor activity. Involved in establishment of epithelial cell polarity. Localizes to the bicellular tight junction; cytosol; and extrinsic component of cytoplasmic side of plasma membrane. Is expressed in sciatic nerve. Orthologous to human CYTH1 (cytohesin 1); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CLM1; CTH-1; CYTIP; cytohesin-1; KIAA4240; mKIAA4240; mSec7-1; PH, SEC7 and coiled-coil domain-containing protein 1; pleckstrin homology, Sec7 and coiled-coil domains 1; Pscd1; SEC7 homolog A
Homo sapiens (human) : CYTH1 (cytohesin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyth1 (cytohesin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cyth1 (cytohesin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CYTH1 (cytohesin 1)
Canis lupus familiaris (dog) : CYTH1 (cytohesin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cyth1 (cytohesin 1)
Sus scrofa (pig) : CYTH1 (cytohesin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3811118,164,166 - 118,248,616 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711118,025,480 - 118,109,906 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611117,980,265 - 118,064,650 (-)NCBImm8
Celera11129,909,098 - 129,993,513 (-)NCBICelera
Cytogenetic Map11 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cyth1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736055
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.