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Pathways
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35 records found for search term Arx
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1344380ARXaristaless related homeoboxThis gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarilX2500369425015965Human455symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1557424Arxaristaless related homeoboxThis gene encodes a transcription factor that plays an important role in the development of forebrain. Male mice lacking this gene have smaller brains, olfactory bulbs and testes, and die within half a day after birth. Mice lacking this gene specifically in ganglionic eminence-derived neurons, incluX9233011392341963Mouse277symbol , old_gene_name , PhenoGen , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1562672Arxaristaless related homeoboxENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN neuron development; axon guidance (ortholog); cell proliferX6201009762022009Rat183symbol , old_gene_name , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
9037244Arxaristaless related homeoboxENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN axon guidance (ortholog); cell proliferation in forebrain (NW_00495550953261455338250Chinchilla64symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
11886815ARXaristaless related homeoboxENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN axon guidance (ortholog); cell proliferation in forebrain (X1759885817612544Bonobo64symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12430458ARXaristaless related homeoboxENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN axon guidance (ortholog); cell proliferation in forebrain (ortholog); cerebral cortex GABAergic interneuron migrationX2054534620556206Dog74symbol , old_gene_namegene, protein-coding, INFERRED [RefSeq]
12444459Arxaristaless related homeoboxENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN axon guidance (ortholog); cell proliferation in forebrain (ortholog); cerebral cortex GABAergic interneuron migrationNW_004936836295090306756Squirrel71symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
14068877ARXaristaless related homeoboxENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN axon guidance (ortholog); cell proliferation in forebrain (ortholog); cerebral cortex GABAergic interneuron migrationPig75symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
14384178arxFlysymbolgene, null
18494137ARXaristaless related homeoboxENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN axon guidance (ortholog); cell proliferation in forebrain (ortholog); cerebral cortex GABAergic interneuron migrationGreen Monkey71symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
18932116Arxaristaless related homeoboxENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN axon guidance (ortholog); cell proliferation in forebraiNaked Mole-Rat72symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
39131321ARXaristaless related homeoboxChinchillasymbolgene, protein-coding
155238040arxTropical Clawed Frogsymbolgene, null
625849584Arxaristaless related homeoboxENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN axon guidance (ortholog); cell proliferation in forebrain (Black Rat64symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
14368659arx-1Roundwormsymbolgene, null
14368656arx-2Roundwormsymbolgene, null
14369524arx-3Roundwormsymbolgene, null
14369527arx-4Roundwormsymbolgene, null
14369531arx-5Roundwormsymbolgene, null
14369534arx-6Roundwormsymbolgene, null
14369538arx-7Roundwormsymbolgene, null
155249109arx.LAfrican Clawed Frogsymbolgene, null
155238039arx.SAfrican Clawed Frogsymbolgene, null
1323790Uba2ubiquitin-like modifier activating enzyme 2Enables SUMO activating enzyme activity. Predicted to be involved in positive regulation of protein sumoylation and protein sumoylation. Part of SUMO activating enzyme complex. Is expressed in several structures, including branchial arch; lens; limb; and neural fold. Orthologous to human UBA2 (ubiqu73384012133868014Mouse136old_gene_name , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1602133UBA2ubiquitin like modifier activating enzyme 2Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of pr193442838134471251Human180old_gene_name , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
14372558ARX1Yeastsymbolgene, null
1563536Arxes1adipocyte-related X-chromosome expressed sequence 1INVOLVED IN fat cell differentiation (ortholog); PARTICIPATES IN biotin metabolic pathway; lysine degradation pathway; FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 1,2-dimethylhydrazine (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog); arsenous acid (ortholog)X103742157103743676Rat24symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1617466Arxes1adipocyte-related X-chromosome expressed sequence 1Acts upstream of or within fat cell differentiation. Located in endoplasmic reticulum. Is expressed in axial musculature; eye; incisor; and nervous system. [provided by Alliance of Genome Resources, Jul 2025]X134934116134935695Mouse22symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1622216Arxes2adipocyte-related X-chromosome expressed sequence 2Acts upstream of or within fat cell differentiation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]X134894569134896108Mouse45symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
2322092Arxes2adipocyte-related X-chromosome expressed sequence 2INVOLVED IN signal peptide processing (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol AX103777456103779036Rat10symbol , PhenoGengene, protein-coding, INFERRED [RefSeq]
68545BCAMbasal cell adhesion molecule (Lutheran blood group)This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This p194480905944821421Human134GenBank Proteingene, protein-coding, REVIEWED [RefSeq]
737036CD44CD44 molecule (IN blood group)The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein part113513917135232402Human638GenBank Proteingene, protein-coding, REVIEWED [RefSeq]
1351810HLA-DQA1major histocompatibility complex, class II, DQ alpha 1HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II mo63263740632655272Human463GenBank Proteingene, protein-coding, REVIEWED [RefSeq]
1604848RHCERh blood group CcEe antigensThe Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the R12536224925430203Human58GenBank Proteingene, protein-coding, REVIEWED [RefSeq]
736735RHDRh blood group D antigenThe Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD p12527248625330445Human92GenBank Proteingene, protein-coding, REVIEWED [RefSeq]