| 2137 | Apod | apolipoprotein D | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN peripheral nervous system axon regeneration; response to axon injury; response to xenobiotic stimulus; ASSOCIATED WITH Brain Injuries; status epilepticus; stroke; FOUND IN cytoplasm; cytosolic ribosome; dendrite; INTERACTS W ITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 82936216 | 82957264 | Rat | 216 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 10180 | Apod | apolipoprotein D | The protein encoded by this gene is a component of high-density lipoprotein (HDL), but is unique in that it shares greater structural similarity to lipocalin than to other members of the apolipoprotein family, and has a wider tissue expression pattern. The encoded protein is involved in lipid metabo lism, and ablation of this gene results in defects in triglyceride metabolism. Elevated levels of this gene product have been observed in multiple tissues of Niemann-Pick disease mouse models, as well as in some tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] | 16 | 31115010 | 31133626 | Mouse | 254 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 737460 | APOD | apolipoprotein D | This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocali ns. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008] | 3 | 195568705 | 195583940 | Human | 218 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8706936 | Apod | apolipoprotein D | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN glucose metabolic process (ortholog); lipid metabolic process (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injurie s (ortholog); gestational diabetes (ortholog); FOUND IN cytoplasm (ortholog); cytosolic ribosome (ortholog); dendrite (ortholog) | NW_004955420 | 13553254 | 13570357 | Chinchilla | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12021590 | APOD | apolipoprotein D | ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); INVOLVED IN peripheral nervous system axon regeneration (ortholog); response to axon injury (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injuries (ortholog); gestational diabetes (ortholog); FOUND IN cytosolic ribosome (ortholog); dendrite (ortholog); neuronal cell body (ortholog) | 3 | 192852887 | 192868233 | Bonobo | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12080808 | APOD | apolipoprotein D | ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN glucose metabolic process (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); negative regulation of focal adhesion assembly (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholo g); Brain Injuries (ortholog); gestational diabetes (ortholog); FOUND IN cytoplasm (ortholog); cytosolic ribosome (ortholog); dendrite (ortholog) | 33 | 30490149 | 30504804 | Dog | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12667810 | Apod | apolipoprotein D | ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); INVOLVED IN peripheral nervous system axon regeneration (ortholog); response to axon injury (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injuries (ortholog); gestational diabetes (ortholog); FOUND IN cytosolic ribosome (ortholog); dendrite (ortholog); neuronal cell body (ortholog) | NW_004936833 | 260798 | 277060 | Squirrel | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14273178 | APOD | apolipoprotein D | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN glucose metabolic process (ortholog); lipid metabolic process (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injurie s (ortholog); gestational diabetes (ortholog); FOUND IN cytoplasm (ortholog); cytosolic ribosome (ortholog); dendrite (ortholog) | | | | Pig | 73 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18342444 | APOD | apolipoprotein D | ENCODES a protein that exhibits cholesterol binding (inferred); lipid binding (inferred); INVOLVED IN peripheral nervous system axon regeneration (ortholog); response to axon injury (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injuries (ortholog); gestational diabetes (ortholog); FOUND IN cytosolic ribosome (ortholog); dendrite (ortholog); neuronal cell body (ortholog) | | | | Green Monkey | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922182 | Apod | apolipoprotein D | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN glucose metabolic process (ortholog); lipid metabolic process (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injurie s (ortholog); gestational diabetes (ortholog); FOUND IN cytosolic ribosome (ortholog); dendrite (ortholog); extracellular space (ortholog) | | | | Naked Mole-Rat | 57 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 626093650 | Apod | apolipoprotein D | ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN glucose metabolic process (ortholog); lipid metabolic process (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injurie s (ortholog); gestational diabetes (ortholog); FOUND IN cytoplasm (ortholog); cytosolic ribosome (ortholog); dendrite (ortholog) | | | | Black Rat | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 2507 | Dmd | dystrophin | ENCODES a protein that exhibits actin binding; integrin binding; lamin binding; INVOLVED IN cell differentiation; cerebral cortex development; muscle cell differentiation; ASSOCIATED WITH abnormal heart echocardiography feature; centrally nucleated skeletal muscle fibers; decreased body length; ASSO CIATED WITH brain edema; Cardiac Fibrosis; Dehydration; FOUND IN astrocyte projection; axon; cell projection; INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | X | 51070098 | 53437845 | Rat | 440 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |