Tp53i3 (tumor protein p53 inducible protein 3) - Rat Genome Database

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Gene: Tp53i3 (tumor protein p53 inducible protein 3) Rattus norvegicus
Analyze
Symbol: Tp53i3
Name: tumor protein p53 inducible protein 3
RGD ID: 41235940
Description: Predicted to enable several functions, including NADPH binding activity; NADPH:quinone reductase activity; and protein homodimerization activity. Predicted to be involved in NADP metabolic process; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: pseudo
RefSeq Status: INFERRED
Previously known as: LOC120093231; quinone oxidoreductase PIG3
RGD Orthologs
Human
Mouse
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8633,537,779 - 33,545,204 (+)NCBIGRCr8
mRatBN7.2627,818,327 - 27,825,753 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx628,110,574 - 28,117,999 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0628,426,478 - 28,433,903 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0627,901,034 - 27,908,460 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amifostine  (ISO)
amsacrine  (ISO)
antimycin A  (ISO)
apigenin  (ISO)
aristolochic acid A  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbamazepine  (ISO)
chloroacetaldehyde  (ISO)
chrysin  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
daunorubicin  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
fenofibrate  (ISO)
fipronil  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
glafenine  (EXP)
glyphosate  (EXP)
ifosfamide  (ISO)
ivermectin  (ISO)
kaempferol  (ISO)
lead(0)  (ISO)
lucanthone  (ISO)
luteolin  (ISO)
malathion  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mitomycin C  (ISO)
myricetin  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
nitric oxide  (ISO)
Nutlin-3  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
parathion  (ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP)
picoxystrobin  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
taurine  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
tolcapone  (EXP)
trametinib  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

Genomics

Comparative Map Data
Tp53i3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8633,537,779 - 33,545,204 (+)NCBIGRCr8
mRatBN7.2627,818,327 - 27,825,753 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx628,110,574 - 28,117,999 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0628,426,478 - 28,433,903 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0627,901,034 - 27,908,460 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Cytogenetic Map6q14NCBI
TP53I3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38224,077,433 - 24,084,834 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl224,077,433 - 24,085,861 (-)EnsemblGRCh38hg38GRCh38
GRCh37224,300,303 - 24,307,704 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36224,153,809 - 24,161,232 (-)NCBINCBI36Build 36hg18NCBI36
Celera224,140,633 - 24,148,056 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef224,039,115 - 24,046,906 (-)NCBIHuRef
CHM1_1224,229,689 - 24,237,471 (-)NCBICHM1_1
T2T-CHM13v2.0224,112,112 - 24,119,520 (-)NCBIT2T-CHM13v2.0
Gm20348
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,860,475 - 4,867,155 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl124,860,494 - 4,867,142 (+)EnsemblGRCm39 Ensembl
GRCm38124,810,475 - 4,817,155 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37124,817,300 - 4,823,951 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera124,742,037 - 4,748,688 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map122.09NCBI
TP53I3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11718,560,123 - 18,566,588 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1718,560,240 - 18,565,958 (-)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1718,458,253 - 18,464,493 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01718,834,076 - 18,840,077 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.01718,730,671 - 18,736,870 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1718,730,610 - 18,736,690 (-)NCBIROS_Cfam_1.0 Ensembl
ROS_Cfam_1.0 Ensembl1718,730,610 - 18,736,690 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11718,571,400 - 18,577,848 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01718,580,093 - 18,586,318 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01718,620,807 - 18,627,079 (-)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Tp53i3
71 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_039078177   ⟹   XP_038934105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2627,818,327 - 27,827,030 (+)NCBI

Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-38265 BioCyc
NCBI Gene LOC120093231 ENTREZGENE
PhenoGen Tp53i3 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-02-15 Tp53i3  tumor protein p53 inducible protein 3  LOC120093231  tumor protein p53 inducible protein 3  Symbol changed 629549 APPROVED
2021-01-27 LOC120093231  tumor protein p53 inducible protein 3      Symbol and Name status set to provisional 70820 PROVISIONAL