Myh1 (myosin heavy chain 1) - Rat Genome Database

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Gene: Myh1 (myosin heavy chain 1) Rattus norvegicus
Analyze
Symbol: Myh1 (Ensembl: Myh2)
Name: myosin heavy chain 1 (Ensembl:myosin heavy chain 2)
RGD ID: 735061
Description: Predicted to enable ATP hydrolysis activity and microfilament motor activity. Involved in muscle contraction. Part of muscle myosin complex. Orthologous to human MYH1 (myosin heavy chain 1); PARTICIPATES IN myocarditis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MYHC; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy polypeptide 1, skeletal muscle, adult; type 2X myosin heavy chain
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81052,384,810 - 52,408,698 (+)NCBIGRCr8
mRatBN7.21051,885,913 - 51,909,699 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1051,885,913 - 51,946,295 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1056,542,792 - 56,566,565 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01056,031,797 - 56,055,568 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01051,542,188 - 51,565,983 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01053,740,841 - 53,764,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,713,938 - 53,848,347 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,493,997 - 53,517,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,894,388 - 53,917,948 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11053,928,512 - 53,931,551 (+)NCBI
Celera1051,068,765 - 51,092,552 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh1RatCongenital Muscular Dystrophy with Central Nervous System Involvement  ISOMYH1 (Homo sapiens)8554872ClinVar Annotator: match by term: Muscular dystrophy more ...ClinVarPMID:25741868
Myh1Ratcongenital myopathy 6  ISOMYH1 (Homo sapiens)8554872ClinVar Annotator: match by term: Myopathy more ...ClinVarPMID:28492532
Myh1RatFukuyama congenital muscular dystrophy  ISOMYH1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital muscular dystrophy-dystroglycanopathy with brain and eye anomalies and type A4ClinVarPMID:25741868

1 to 20 of 69 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh1Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of MYH1 mRNA]CTDPMID:31150632
Myh1Rat1,2-dimethylhydrazine decreases expressionISOMyh1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of MYH1 mRNACTDPMID:22206623
Myh1Rat17beta-estradiol affects expressionISOMyh1 (Mus musculus)6480464Estradiol affects the expression of MYH1 mRNACTDPMID:19484750
Myh1Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of MYH1 mRNACTDPMID:32145629
Myh1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of MYH1 mRNACTDPMID:24780913
Myh1Rataconitine increases expressionEXP 6480464Aconitine results in increased expression of MYH1 proteinCTDPMID:33236894
Myh1Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of MYH1 mRNACTDPMID:28606764
Myh1Rataldehydo-D-glucose multiple interactionsISOMyh1 (Mus musculus)6480464[lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of MYH1 mRNACTDPMID:37567420
Myh1Ratall-trans-retinoic acid multiple interactionsISOMyh1 (Mus musculus)6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MYH1 mRNACTDPMID:36189433
Myh1Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of MYH1 mRNACTDPMID:16483693
Myh1Ratarsane decreases expressionISOMyh1 (Mus musculus)6480464Arsenic results in decreased expression of MYH1 mRNA and Arsenic results in decreased expression of MYH1 proteinCTDPMID:22552367 and PMID:33124703
Myh1Ratarsenic atom decreases expressionISOMyh1 (Mus musculus)6480464Arsenic results in decreased expression of MYH1 mRNA and Arsenic results in decreased expression of MYH1 proteinCTDPMID:22552367 and PMID:33124703
Myh1Ratbenzo[a]pyrene affects methylationISOMYH1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of MYH1 5' UTR and Benzo(a)pyrene affects the methylation of MYH1 promoterCTDPMID:27901495
Myh1Ratbenzo[a]pyrene diol epoxide I decreases expressionISOMYH1 (Homo sapiens)64804647 more ...CTDPMID:24431215
Myh1Ratbenzo[a]pyrene diol epoxide I multiple interactionsISOMYH1 (Homo sapiens)6480464pyrrolidine dithiocarbamic acid inhibits the reaction [7 more ...CTDPMID:24431215
Myh1Ratbis(2-ethylhexyl) phthalate increases expressionISOMyh1 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of MYH1 mRNACTDPMID:28085963
Myh1Ratbisphenol A affects expressionISOMyh1 (Mus musculus)6480464bisphenol A affects the expression of MYH1 mRNACTDPMID:27082013
Myh1Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of MYH1 mRNACTDPMID:32145629
Myh1Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of MYH1 mRNACTDPMID:30816183 and PMID:32528016
Myh1Ratbisphenol A multiple interactionsISOMYH1 (Homo sapiens)6480464[Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of MYH1 proteinCTDPMID:31629898

1 to 20 of 69 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh1Ratmuscle contraction  IDA 1599030 RGD 
Myh1Ratstriated muscle contraction  TAS 1302818 RGD 

Cellular Component

  

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh1Ratactin filament binding enablesIEAInterPro:IPR0089891600115GO_REF:0000002InterProGO_REF:0000002
Myh1RatATP binding enablesIEAUniRule:UR0006864691600115GO_REF:0000104UniProtGO_REF:0000104
Myh1RatATP hydrolysis activity  TAS 1302818 RGD 
Myh1Ratcalmodulin binding enablesIEAUniProtKB-KW:KW-01121600115GO_REF:0000043UniProtGO_REF:0000043
Myh1Ratmicrofilament motor activity  TAS 1302818 RGD 
Myh1Ratprotein binding enablesISOMYH1 (Homo sapiens)1624291UniProtKB:A1A4E9 more ...RGDPMID:25416956 and PMID:32296183

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myh1Ratmyocarditis pathway  IEA 6907045 KEGGrno:05416

#
Reference Title
Reference Citation
1. Coupled expression of troponin T and troponin I isoforms in single skeletal muscle fibers correlates with contractility. Brotto MA, etal., Am J Physiol Cell Physiol. 2006 Feb;290(2):C567-76. Epub 2005 Sep 28.
2. Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene. DeNardi C, etal., J Cell Biol 1993 Nov;123(4):823-35.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8287498   PMID:10460968   PMID:11732910   PMID:15121898   PMID:15578571   PMID:16839454   PMID:17030512   PMID:17670891   PMID:18310078   PMID:18761673   PMID:19369448   PMID:19738937  
PMID:22206666   PMID:22464481   PMID:23058369   PMID:33573052  



Myh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81052,384,810 - 52,408,698 (+)NCBIGRCr8
mRatBN7.21051,885,913 - 51,909,699 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1051,885,913 - 51,946,295 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1056,542,792 - 56,566,565 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01056,031,797 - 56,055,568 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01051,542,188 - 51,565,983 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01053,740,841 - 53,764,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,713,938 - 53,848,347 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,493,997 - 53,517,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,894,388 - 53,917,948 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11053,928,512 - 53,931,551 (+)NCBI
Celera1051,068,765 - 51,092,552 (+)NCBICelera
Cytogenetic Map10q24NCBI
MYH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381710,492,307 - 10,518,542 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1710,492,307 - 10,518,542 (-)EnsemblGRCh38hg38GRCh38
GRCh371710,395,624 - 10,421,859 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361710,336,349 - 10,362,584 (-)NCBINCBI36Build 36hg18NCBI36
Build 341710,336,352 - 10,360,684NCBI
Celera1710,426,467 - 10,452,723 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef1710,295,198 - 10,321,455 (-)NCBIHuRef
CHM1_11710,405,462 - 10,431,716 (-)NCBICHM1_1
T2T-CHM13v2.01710,399,791 - 10,426,053 (-)NCBIT2T-CHM13v2.0
Myh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,090,922 - 67,115,401 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,090,878 - 67,115,401 (+)EnsemblGRCm39 Ensembl
GRCm381167,200,102 - 67,224,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,200,052 - 67,224,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv371167,013,616 - 67,038,077 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361167,016,309 - 67,040,770 (+)NCBIMGSCv36mm8
Celera1174,138,951 - 74,163,820 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.59NCBI
Myh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554676,685,753 - 6,707,491 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554676,684,104 - 6,707,597 (+)NCBIChiLan1.0ChiLan1.0
MYH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21963,230,666 - 63,257,025 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11768,041,211 - 68,067,576 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01741,134,861 - 41,161,226 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11745,882,261 - 45,908,472 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1745,882,261 - 45,908,467 (+)Ensemblpanpan1.1panPan2
MYH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1534,810,791 - 34,838,177 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl534,810,921 - 34,837,904 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha534,947,344 - 34,972,447 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0534,915,611 - 34,943,047 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl534,915,741 - 34,942,730 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1534,881,239 - 34,906,337 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0534,838,682 - 34,863,782 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0535,019,632 - 35,044,733 (-)NCBIUU_Cfam_GSD_1.0
Myh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560249,889,783 - 49,914,464 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365953,363,975 - 3,388,385 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365953,363,974 - 3,416,849 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1255,225,590 - 55,249,340 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11255,225,581 - 55,251,495 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21257,965,087 - 57,984,759 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1169,834,434 - 9,860,744 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605911,481,624 - 11,507,924 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.

.
Variants in Myh1
100 total Variants

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:49
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000004295
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 72 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103571058068663659Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104698969968663659Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105166340575085664Rat

1 to 10 of 72 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
2 11 21 68 26 29 10 19 10 81 51 60 10 28 19



Ensembl Acc Id: ENSRNOT00000004236   ⟹   ENSRNOP00000004236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1053,713,938 - 53,738,031 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000004295   ⟹   ENSRNOP00000004295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,885,913 - 51,909,699 (+)Ensembl
Rnor_6.0 Ensembl1053,740,841 - 53,764,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000045718   ⟹   ENSRNOP00000046362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,923,355 - 51,946,295 (+)Ensembl
Rnor_6.0 Ensembl1053,778,662 - 53,801,603 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082871   ⟹   ENSRNOP00000072943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,885,913 - 51,946,295 (+)Ensembl
Rnor_6.0 Ensembl1053,781,239 - 53,848,347 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085582   ⟹   ENSRNOP00000071998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1051,885,913 - 51,909,699 (+)Ensembl
Rnor_6.0 Ensembl1053,713,941 - 53,764,500 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086599   ⟹   ENSRNOP00000071422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1053,713,938 - 53,848,347 (+)Ensembl
RefSeq Acc Id: NM_001135158   ⟹   NP_001128630
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81052,384,912 - 52,408,698 (+)NCBI
mRatBN7.21051,885,913 - 51,909,699 (+)NCBI
Rnor_6.01053,740,841 - 53,764,610 (+)NCBI
Rnor_5.01053,493,997 - 53,517,766 (+)NCBI
RGSC_v3.41053,894,388 - 53,917,948 (+)RGD
Celera1051,068,765 - 51,092,552 (+)RGD
Sequence:
RefSeq Acc Id: XM_039085434   ⟹   XP_038941362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81052,384,810 - 52,408,696 (+)NCBI
mRatBN7.21051,886,199 - 51,909,592 (+)NCBI
Protein RefSeqs NP_001128630 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941362 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB29713 (Get FASTA)   NCBI Sequence Viewer  
  AAD51613 (Get FASTA)   NCBI Sequence Viewer  
  ABI34117 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004295.7
  ENSRNOP00000071998.2
  ENSRNOP00000072943.2
RefSeq Acc Id: NP_001128630   ⟸   NM_001135158
- UniProtKB: F1LRV9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072943   ⟸   ENSRNOT00000082871
Ensembl Acc Id: ENSRNOP00000046362   ⟸   ENSRNOT00000045718
Ensembl Acc Id: ENSRNOP00000004295   ⟸   ENSRNOT00000004295
Ensembl Acc Id: ENSRNOP00000004236   ⟸   ENSRNOT00000004236

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13697292
Promoter ID:EPDNEW_R7815
Type:multiple initiation site
Name:Myh4_1
Description:myosin heavy chain 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7816  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01053,740,840 - 53,740,900EPDNEW


1 to 40 of 44 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-24656 BioCyc
Ensembl Genes ENSRNOG00000049695 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004295.7 UniProtKB/TrEMBL
  ENSRNOT00000082871.2 UniProtKB/TrEMBL
  ENSRNOT00000085582.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/TrEMBL
  1.20.5.370 UniProtKB/TrEMBL
  1.20.5.4820 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  2.30.30.360 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  6.10.250.2420 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/TrEMBL
  Myosin_tail UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  XRCC4-like_C UniProtKB/TrEMBL
NCBI Gene 287408 ENTREZGENE
PANTHER MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/TrEMBL
  MYOSIN-1 UniProtKB/TrEMBL
  MYOSIN-4 UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/TrEMBL
PhenoGen Myh1 PhenoGen
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049695 RatGTEx
SMART MYSc UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP Myosin rod fragments UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  Tropomyosin UniProtKB/TrEMBL
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-29 Myh1  myosin heavy chain 1  Myh1  myosin, heavy chain 1, skeletal muscle, adult  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-05 Myh1  myosin, heavy chain 1, skeletal muscle, adult  Myh1  myosin, heavy polypeptide 1, skeletal muscle, adult  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Myh1  myosin, heavy polypeptide 1, skeletal muscle, adult    type 2X myosin heavy chain  Name updated 1299863 APPROVED
2004-09-10 Myh1  type 2X myosin heavy chain  MYHC    Symbol and Name updated 1299863 APPROVED

Note Type Note Reference
gene_expression highly expressed in diaphram 1302818
gene_other speed of shortening of muscle fibers expressing 2X-MyHC is intermediate between that of fibers expressing 2A-MyHC and 2B-MyHC 1302818