MYH1 (myosin, heavy chain 1, skeletal muscle, adult) - Rat Genome Database

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Gene: MYH1 (myosin, heavy chain 1, skeletal muscle, adult) Sus scrofa
Analyze
Symbol: MYH1
Name: myosin, heavy chain 1, skeletal muscle, adult
RGD ID: 13957183
Description: ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); ATP binding (inferred); INVOLVED IN muscle contraction (ortholog); ASSOCIATED WITH Congenital Muscular Dystrophy with Central Nervous System Involvement (ortholog); congenital myopathy 6 (ortholog); Fukuyama congenital muscular dystrophy (ortholog); FOUND IN muscle myosin complex (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: myHC-2x; myosin heavy chain 1; myosin heavy chain 2x; myosin heavy chain isoform fast type; myosin heavy chain, skeletal muscle, adult 1; myosin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1255,225,590 - 55,249,340 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11255,225,581 - 55,251,495 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21257,965,087 - 57,984,759 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
muscle contraction  (IBA,IEA,ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22061506   PMID:22301074   PMID:26847462  


Genomics

Comparative Map Data
MYH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1255,225,590 - 55,249,340 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11255,225,581 - 55,251,495 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21257,965,087 - 57,984,759 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381710,492,307 - 10,518,542 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1710,492,307 - 10,518,542 (-)EnsemblGRCh38hg38GRCh38
GRCh371710,395,624 - 10,421,859 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361710,336,349 - 10,362,584 (-)NCBINCBI36Build 36hg18NCBI36
Build 341710,336,352 - 10,360,684NCBI
Celera1710,426,467 - 10,452,723 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef1710,295,198 - 10,321,455 (-)NCBIHuRef
CHM1_11710,405,462 - 10,431,716 (-)NCBICHM1_1
T2T-CHM13v2.01710,399,791 - 10,426,053 (-)NCBIT2T-CHM13v2.0
Myh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,090,922 - 67,115,401 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,090,878 - 67,115,401 (+)EnsemblGRCm39 Ensembl
GRCm381167,200,102 - 67,224,577 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,200,052 - 67,224,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv371167,013,616 - 67,038,077 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361167,016,309 - 67,040,770 (+)NCBIMGSCv36mm8
Celera1174,138,951 - 74,163,820 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.59NCBI
Myh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81052,384,810 - 52,408,698 (+)NCBIGRCr8
mRatBN7.21051,885,913 - 51,909,699 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1051,885,913 - 51,946,295 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1056,542,792 - 56,566,565 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01056,031,797 - 56,055,568 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01051,542,188 - 51,565,983 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01053,740,841 - 53,764,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,713,938 - 53,848,347 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,493,997 - 53,517,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,894,388 - 53,917,948 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11053,928,512 - 53,931,551 (+)NCBI
Celera1051,068,765 - 51,092,552 (+)NCBICelera
Cytogenetic Map10q24NCBI
Myh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554676,685,753 - 6,707,491 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554676,684,104 - 6,707,597 (+)NCBIChiLan1.0ChiLan1.0
MYH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21963,230,666 - 63,257,025 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11768,041,211 - 68,067,576 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01741,134,861 - 41,161,226 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11745,882,261 - 45,908,472 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1745,882,261 - 45,908,467 (+)Ensemblpanpan1.1panPan2
MYH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1534,781,364 - 34,808,277 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl534,781,367 - 34,806,850 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha534,917,890 - 34,942,464 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0534,885,509 - 34,913,089 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl534,886,223 - 34,911,669 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1534,851,786 - 34,876,357 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0534,809,228 - 34,833,801 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0534,990,179 - 35,014,752 (-)NCBIUU_Cfam_GSD_1.0
Myh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560249,889,783 - 49,914,464 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365953,363,975 - 3,388,385 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365953,363,974 - 3,416,849 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1169,834,434 - 9,860,744 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605911,481,624 - 11,507,924 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in MYH1
894 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000019596   ⟹   ENSSSCP00000019077
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1255,225,590 - 55,249,340 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000064728   ⟹   ENSSSCP00000053821
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1255,225,590 - 55,249,340 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000073295   ⟹   ENSSSCP00000059984
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1255,225,590 - 55,249,340 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000077008   ⟹   ENSSSCP00000073820
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1255,225,590 - 55,249,340 (-)Ensembl
RefSeq Acc Id: NM_001104951   ⟹   NP_001098421
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11255,225,686 - 55,249,342 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021066024   ⟹   XP_020921683
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11255,225,581 - 55,251,495 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020921683   ⟸   XM_021066024
- Peptide Label: isoform X1
- UniProtKB: F1SS65 (UniProtKB/TrEMBL),   A0A8D1DFX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001098421   ⟸   NM_001104951
- UniProtKB: Q9TV61 (UniProtKB/Swiss-Prot),   A0A8D1DFX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000053821   ⟸   ENSSSCT00000064728
RefSeq Acc Id: ENSSSCP00000073820   ⟸   ENSSSCT00000077008
RefSeq Acc Id: ENSSSCP00000059984   ⟸   ENSSSCT00000073295
RefSeq Acc Id: ENSSSCP00000019077   ⟸   ENSSSCT00000019596
Protein Domains
IQ   Myosin motor   Myosin N-terminal SH3-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000054680 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00040011670 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000019596 ENTREZGENE
  ENSSSCT00000019596.5 UniProtKB/TrEMBL
  ENSSSCT00000064728.3 UniProtKB/TrEMBL
  ENSSSCT00000073295.2 UniProtKB/TrEMBL
  ENSSSCT00000077008.2 UniProtKB/TrEMBL
  ENSSSCT00040015881.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.4820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.30.360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.2420 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_tail UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  XRCC4-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100125538 UniProtKB/Swiss-Prot
NCBI Gene MYH1 ENTREZGENE
PANTHER MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYOSIN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MYSc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Myosin rod fragments UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  Tropomyosin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287BCH4_PIG UniProtKB/TrEMBL
  A0A5G2Q7D6_PIG UniProtKB/TrEMBL
  A0A5G2RBU2_PIG UniProtKB/TrEMBL
  A0A8D1DFX3 ENTREZGENE, UniProtKB/TrEMBL
  F1SS65 ENTREZGENE, UniProtKB/TrEMBL
  MYH1_PIG UniProtKB/Swiss-Prot, ENTREZGENE