Pcdh8 (protocadherin 8) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Pcdh8 (protocadherin 8) Rattus norvegicus
Analyze
Symbol: Pcdh8
Name: protocadherin 8
RGD ID: 69350
Description: Predicted to enable calcium ion binding activity. Involved in chemical synaptic transmission; modulation of chemical synaptic transmission; and regulation of synaptic membrane adhesion. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic membrane. Orthologous to human PCDH8 (protocadherin 8); INTERACTS WITH 1,3-dinitrobenzene; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: activity-regulated cadherin-like protein; Arcadlin; protocadherin-8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81561,607,521 - 61,612,090 (-)NCBIGRCr8
mRatBN7.21555,198,470 - 55,203,039 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1555,198,459 - 55,205,872 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1559,313,542 - 59,317,323 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01560,431,918 - 60,435,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01557,256,791 - 57,260,575 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01562,196,469 - 62,201,498 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1562,197,060 - 62,200,837 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01565,856,803 - 65,861,374 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41561,056,994 - 61,060,741 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11561,072,773 - 61,076,521 (-)NCBI
Celera1554,773,168 - 54,776,945 (-)NCBICelera
Cytogenetic Map15q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pcdh8Ratchromosome 13q14 deletion syndrome  ISOPCDH8 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 13q14 deletion syndromeClinVar 
Pcdh8Ratintellectual disability  ISOPCDH8 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pcdh8RatProstatic Neoplasms  ISOPCDH8 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19208208

1 to 20 of 79 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pcdh8Rat1,3-dinitrobenzene decreases expressionEXP 64804643-dinitrobenzene results in decreased expression of PCDH8 mRNACTDPMID:24140754
Pcdh8Rat17beta-estradiol multiple interactionsISOPCDH8 (Homo sapiens)6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PCDH8 mRNACTDPMID:19619570
Pcdh8Rat17beta-estradiol increases expressionISOPCDH8 (Homo sapiens)6480464Estradiol results in increased expression of PCDH8 mRNACTDPMID:19619570
Pcdh8Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionEXP 64804642 more ...CTDPMID:27291303
Pcdh8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPCDH8 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of PCDH8 mRNACTDPMID:19619570
Pcdh8Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPcdh8 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PCDH8 mRNACTDPMID:21570461
Pcdh8Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPcdh8 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of PCDH8 mRNACTDPMID:19465110
Pcdh8Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPCDH8 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of PCDH8 mRNACTDPMID:19901195
Pcdh8Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPCDH8 (Homo sapiens)6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PCDH8 mRNACTDPMID:19619570
Pcdh8Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expressionISOPCDH8 (Homo sapiens)64804642 more ...CTDPMID:26705709
Pcdh8Rat4,4'-sulfonyldiphenol affects methylationISOPcdh8 (Mus musculus)6480464bisphenol S affects the methylation of PCDH8 exonCTDPMID:33297965
Pcdh8Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PCDH8 mRNACTDPMID:24780913 and PMID:25825206
Pcdh8Ratacetaldehyde affects expressionISOPcdh8 (Mus musculus)6480464Acetaldehyde affects the expression of PCDH8 mRNACTDPMID:22634333
Pcdh8Ratafimoxifene increases expressionISOPCDH8 (Homo sapiens)6480464afimoxifene results in increased expression of PCDH8 mRNACTDPMID:19901195
Pcdh8Rataflatoxin B1 decreases methylationISOPCDH8 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of PCDH8 geneCTDPMID:27153756
Pcdh8Ratall-trans-retinoic acid increases expressionISOPCDH8 (Homo sapiens)6480464Tretinoin results in increased expression of PCDH8 mRNACTDPMID:21934132
Pcdh8Ratall-trans-retinoic acid multiple interactionsISOPcdh8 (Mus musculus)6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PCDH8 mRNACTDPMID:36189433
Pcdh8Ratall-trans-retinoic acid decreases expressionISOPcdh8 (Mus musculus)6480464Tretinoin results in decreased expression of PCDH8 mRNACTDPMID:36189433
Pcdh8Ratamiodarone increases expressionISOPCDH8 (Homo sapiens)6480464Amiodarone results in increased expression of PCDH8 mRNACTDPMID:19774075
Pcdh8Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of PCDH8 mRNACTDPMID:16483693

1 to 20 of 79 rows

Biological Process
1 to 10 of 10 rows

  
1 to 10 of 10 rows

Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pcdh8Ratdendrite located_inIEAUniProtKB-SubCell:SL-02831600115GO_REF:0000044UniProtGO_REF:0000044
Pcdh8Ratglutamatergic synapse is_active_inIMP 13702360PMID:17988630SynGO 
Pcdh8Ratglutamatergic synapse is_active_inIDA 13702360PMID:17988630SynGO 
Pcdh8Ratplasma membrane is_active_inIBAMGI:106671 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pcdh8Ratpostsynaptic membrane is_active_inIDA 13702360PMID:17988630SynGO 
Pcdh8Ratpresynaptic membrane located_inIEAUniProtKB-SubCell:SL-02221600115GO_REF:0000044UniProtGO_REF:0000044
Pcdh8RatSchaffer collateral - CA1 synapse is_active_inEXP 68758PMID:10383464SynGO 
Pcdh8RatSchaffer collateral - CA1 synapse is_active_inIDA 68758PMID:10383464SynGO 
Pcdh8Ratsynapse is_active_inIDA 68758PMID:10383464SynGO 
1 to 9 of 9 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pcdh8Ratcalcium ion binding enablesIEAInterPro:IPR002126 and InterPro:IPR0159191600115GO_REF:0000002InterProGO_REF:0000002


1 to 10 of 10 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
9. Arcadlin is a neural activity-regulated cadherin involved in long term potentiation. Yamagata K, etal., J Biol Chem 1999 Jul 2;274(27):19473-1979.
10. Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2beta and p38 MAP kinases. Yasuda S, etal., Neuron. 2007 Nov 8;56(3):456-71. doi: 10.1016/j.neuron.2007.08.020.
1 to 10 of 10 rows
PMID:12477932   PMID:12591245   PMID:31981722  



Pcdh8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81561,607,521 - 61,612,090 (-)NCBIGRCr8
mRatBN7.21555,198,470 - 55,203,039 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1555,198,459 - 55,205,872 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1559,313,542 - 59,317,323 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01560,431,918 - 60,435,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01557,256,791 - 57,260,575 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01562,196,469 - 62,201,498 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1562,197,060 - 62,200,837 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01565,856,803 - 65,861,374 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41561,056,994 - 61,060,741 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11561,072,773 - 61,076,521 (-)NCBI
Celera1554,773,168 - 54,776,945 (-)NCBICelera
Cytogenetic Map15q12NCBI
PCDH8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381352,842,889 - 52,848,640 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1352,842,889 - 52,848,641 (-)EnsemblGRCh38hg38GRCh38
GRCh371353,417,024 - 53,422,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361352,316,110 - 52,320,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 341352,316,111 - 52,320,775NCBI
Celera1334,403,981 - 34,408,646 (-)NCBICelera
Cytogenetic Map13q14.3NCBI
HuRef1334,132,296 - 34,136,846 (-)NCBIHuRef
CHM1_11353,386,066 - 53,390,732 (-)NCBICHM1_1
T2T-CHM13v2.01352,058,334 - 52,064,085 (-)NCBIT2T-CHM13v2.0
Pcdh8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391480,004,224 - 80,008,752 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1480,004,215 - 80,008,752 (-)EnsemblGRCm39 Ensembl
GRCm381479,766,772 - 79,771,312 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1479,766,775 - 79,771,312 (-)EnsemblGRCm38mm10GRCm38
MGSCv371480,166,582 - 80,171,119 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361478,500,948 - 78,505,388 (-)NCBIMGSCv36mm8
Celera1477,267,150 - 77,271,687 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1442.76NCBI
Pcdh8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540450,403,752 - 50,413,264 (-)NCBIChiLan1.0ChiLan1.0
LOC100983617
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21454,183,685 - 54,188,750 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11352,827,777 - 52,833,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01333,880,543 - 33,886,243 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11352,687,943 - 52,692,601 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1352,688,522 - 52,692,399 (-)Ensemblpanpan1.1panPan2
PCDH8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1229,860,590 - 9,865,298 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl229,860,827 - 9,865,412 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha229,857,555 - 9,862,239 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02210,085,702 - 10,090,390 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2210,085,937 - 10,090,183 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1229,782,421 - 9,787,104 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0229,832,472 - 9,837,157 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,847,219 - 9,851,906 (-)NCBIUU_Cfam_GSD_1.0
LOC101972150
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945151,178,242 - 151,182,890 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936667716,625 - 721,503 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936667716,802 - 721,441 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100155738
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1126,127,401 - 26,132,123 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11126,127,398 - 26,133,481 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21126,882,342 - 26,887,069 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PCDH8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1330,602,449 - 30,610,656 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl330,602,321 - 30,606,926 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605713,206,860 - 13,211,564 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pcdh8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474814,285,475 - 14,290,166 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474814,285,553 - 14,290,236 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Pcdh8
17 total Variants

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:33
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000017599
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155079449473699215Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat

1 to 10 of 25 rows
42.MMHAP38FLF6.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21555,199,005 - 55,199,187 (+)MAPPERmRatBN7.2
Rnor_6.01562,197,005 - 62,197,186NCBIRnor6.0
Rnor_5.01565,857,339 - 65,857,520UniSTSRnor5.0
RGSC_v3.41561,056,939 - 61,057,120UniSTSRGSC3.4
Celera1554,773,113 - 54,773,294UniSTS
Cytogenetic Map15q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
7 3 12 109 42 25 22 8 22 2 112 35 93 45 54 3



Ensembl Acc Id: ENSRNOT00000017599   ⟹   ENSRNOP00000017599
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1555,198,459 - 55,205,872 (-)Ensembl
Rnor_6.0 Ensembl1562,197,060 - 62,200,837 (-)Ensembl
RefSeq Acc Id: NM_001411975   ⟹   NP_001398904
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,607,521 - 61,612,090 (-)NCBI
mRatBN7.21555,198,470 - 55,203,039 (-)NCBI
RefSeq Acc Id: NM_022868   ⟹   NP_074059
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,607,521 - 61,612,090 (-)NCBI
mRatBN7.21555,198,470 - 55,203,039 (-)NCBI
Rnor_6.01562,197,060 - 62,200,837 (-)NCBI
Rnor_5.01565,856,803 - 65,861,374 (-)NCBI
RGSC_v3.41561,056,994 - 61,060,741 (-)RGD
Celera1554,773,168 - 54,776,945 (-)RGD
Sequence:
Protein RefSeqs NP_001398904 (Get FASTA)   NCBI Sequence Viewer  
  NP_074059 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI28738 (Get FASTA)   NCBI Sequence Viewer  
  BAA82442 (Get FASTA)   NCBI Sequence Viewer  
  D3ZE55 (Get FASTA)   NCBI Sequence Viewer  
  EDM02373 (Get FASTA)   NCBI Sequence Viewer  
  EDM02374 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017599.3
RefSeq Acc Id: NP_074059   ⟸   NM_022868
- Peptide Label: isoform 2 precursor
- UniProtKB: A6HU10 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017599   ⟸   ENSRNOT00000017599
RefSeq Acc Id: NP_001398904   ⟸   NM_001411975
- Peptide Label: isoform 1 precursor
- UniProtKB: D3ZE55 (UniProtKB/Swiss-Prot),   A1A5N4 (UniProtKB/Swiss-Prot),   Q9WVR2 (UniProtKB/Swiss-Prot)
Cadherin

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZE55-F1-model_v2 AlphaFold D3ZE55 1-1069 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-12983 BioCyc
Ensembl Genes ENSRNOG00000013101 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017599.4 UniProtKB/Swiss-Prot
Gene3D-CATH Cadherins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8362872 IMAGE-MGC_LOAD
InterPro Cadherin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protocadherin/Cadherin-CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64865 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156642 IMAGE-MGC_LOAD
NCBI Gene 64865 ENTREZGENE
PANTHER CADHERIN-87A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTOCADHERIN-8 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam Cadherin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cadherin_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pcdh8 PhenoGen
PRINTS CADHERIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013101 RatGTEx
SMART SM00112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Cadherin-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
TIGR TC232455
UniProt A1A5N4 ENTREZGENE
  A6HU10 ENTREZGENE, UniProtKB/TrEMBL
  D3ZE55 ENTREZGENE, UniProtKB/Swiss-Prot
  Q9WVR2 ENTREZGENE
UniProt Secondary A1A5N4 UniProtKB/Swiss-Prot
  Q9WVR2 UniProtKB/Swiss-Prot
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Pcdh8  protocadherin 8      Name updated 70584 APPROVED

Note Type Note Reference
gene_domains contains six cadherin repeats 68758
gene_expression expressed in synapses 68758
gene_protein 972 amino acids; 103.7 kDa, 68758
gene_regulation induced in hippocampal granule cells by seizures, and by N-methyl-D-aspartate-dependent synaptic activity in long term potentiation 68758