Pcdh8 (protocadherin 8) - Rat Genome Database

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Gene: Pcdh8 (protocadherin 8) Heterocephalus glaber
Analyze
Symbol: Pcdh8
Name: protocadherin 8
RGD ID: 18921990
Description: ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN chemical synaptic transmission (ortholog); modulation of chemical synaptic transmission (ortholog); morphogenesis of embryonic epithelium (ortholog); ASSOCIATED WITH chromosome 13q14 deletion syndrome (ortholog); intellectual disability (ortholog); Prostatic Neoplasms (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynaptic membrane (ortholog); Schaffer collateral - CA1 synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protocadherin-8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474814,285,475 - 14,290,166 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474814,285,553 - 14,290,236 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Pcdh8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474814,285,475 - 14,290,166 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474814,285,553 - 14,290,236 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PCDH8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381352,842,889 - 52,848,640 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1352,842,889 - 52,848,641 (-)EnsemblGRCh38hg38GRCh38
GRCh371353,417,024 - 53,422,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361352,316,110 - 52,320,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 341352,316,111 - 52,320,775NCBI
Celera1334,403,981 - 34,408,646 (-)NCBICelera
Cytogenetic Map13q14.3NCBI
HuRef1334,132,296 - 34,136,846 (-)NCBIHuRef
CHM1_11353,386,066 - 53,390,732 (-)NCBICHM1_1
T2T-CHM13v2.01352,058,334 - 52,064,085 (-)NCBIT2T-CHM13v2.0
Pcdh8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391480,004,224 - 80,008,752 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1480,004,215 - 80,008,752 (-)EnsemblGRCm39 Ensembl
GRCm381479,766,772 - 79,771,312 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1479,766,775 - 79,771,312 (-)EnsemblGRCm38mm10GRCm38
MGSCv371480,166,582 - 80,171,119 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361478,500,948 - 78,505,388 (-)NCBIMGSCv36mm8
Celera1477,267,150 - 77,271,687 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1442.76NCBI
Pcdh8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81561,607,521 - 61,612,090 (-)NCBIGRCr8
mRatBN7.21555,198,470 - 55,203,039 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1555,198,459 - 55,205,872 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1559,313,542 - 59,317,323 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01560,431,918 - 60,435,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01557,256,791 - 57,260,575 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01562,196,469 - 62,201,498 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1562,197,060 - 62,200,837 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01565,856,803 - 65,861,374 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41561,056,994 - 61,060,741 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11561,072,773 - 61,076,521 (-)NCBI
Celera1554,773,168 - 54,776,945 (-)NCBICelera
Cytogenetic Map15q12NCBI
Pcdh8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540450,403,752 - 50,413,264 (-)NCBIChiLan1.0ChiLan1.0
LOC100983617
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21454,183,685 - 54,188,750 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11352,827,777 - 52,833,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01333,880,543 - 33,886,243 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11352,687,943 - 52,692,601 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1352,688,522 - 52,692,399 (-)Ensemblpanpan1.1panPan2
PCDH8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1229,860,590 - 9,865,298 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl229,860,827 - 9,865,412 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha229,857,555 - 9,862,239 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02210,085,702 - 10,090,390 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2210,085,937 - 10,090,183 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1229,782,421 - 9,787,104 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0229,832,472 - 9,837,157 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,847,219 - 9,851,906 (-)NCBIUU_Cfam_GSD_1.0
LOC101972150
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945151,178,242 - 151,182,890 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936667716,625 - 721,503 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936667716,802 - 721,441 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100155738
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1126,127,401 - 26,132,123 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11126,127,398 - 26,133,481 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21126,882,342 - 26,887,069 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PCDH8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1330,602,449 - 30,610,656 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl330,602,321 - 30,606,926 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605713,206,860 - 13,211,564 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000004582   ⟹   ENSHGLP00000004520
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474814,285,475 - 14,290,166 (-)Ensembl
RefSeq Acc Id: XM_004844268   ⟹   XP_004844325
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474814,285,553 - 14,290,236 (-)NCBI
RefSeq Acc Id: XM_013072069   ⟹   XP_012927523
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474814,285,553 - 14,290,232 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004844325 (Get FASTA)   NCBI Sequence Viewer  
  XP_012927523 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004520
Reference Protein Sequences
RefSeq Acc Id: XP_004844325   ⟸   XM_004844268
- Peptide Label: isoform X1
- UniProtKB: G5BN31 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012927523   ⟸   XM_013072069
- Peptide Label: isoform X2
- UniProtKB: G5BN31 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000004520   ⟸   ENSHGLT00000004582


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003306 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004582 ENTREZGENE
Gene3D-CATH Cadherins UniProtKB/TrEMBL
InterPro Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Cadherin_N UniProtKB/TrEMBL
NCBI Gene Pcdh8 ENTREZGENE
PANTHER CADHERIN-87A UniProtKB/TrEMBL
  PROTOCADHERIN-8 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Cadherin_2 UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP Cadherin-like UniProtKB/TrEMBL
UniProt G5BN31 ENTREZGENE, UniProtKB/TrEMBL