St3gal2 (ST3 beta-galactoside alpha-2,3-sialyltransferase 2) - Rat Genome Database

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Gene: St3gal2 (ST3 beta-galactoside alpha-2,3-sialyltransferase 2) Rattus norvegicus
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Symbol: St3gal2
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 2
RGD ID: 68413
Description: Enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Involved in ganglioside biosynthetic process via lactosylceramide. Predicted to be located in Golgi membrane. Predicted to be active in membrane. Orthologous to human ST3GAL2 (ST3 beta-galactoside alpha-2,3-sialyltransferase 2); PARTICIPATES IN ganglioside metabolic pathway; globoside metabolic pathway; keratan sulfate biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha 2,3-ST 2; beta-galactoside alpha-2,3-sialyltransferase 2; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; gal-NAc6S; monosialoganglioside sialyltransferase; sialyltransferase 4B (beta-galactoside alpha-2,3-sialyltransferase); sialyltransferase 5; SIAT4-B; Siat4b; Siat5; ST3Gal II; ST3GALA.2; ST3GalII
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,798,112 - 55,849,226 (+)NCBIGRCr8
mRatBN7.21938,888,851 - 38,939,874 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,923,999 - 38,939,869 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1945,728,513 - 45,744,388 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,381,856 - 46,397,731 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01948,692,765 - 48,708,643 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01943,273,251 - 43,324,265 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1943,274,493 - 43,290,363 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01954,101,504 - 54,152,583 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,873,202 - 40,889,072 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,892,278 - 40,892,994 (-)NCBI
Celera1938,316,282 - 38,332,162 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
St3gal2Ratautosomal dominant dyskeratosis congenita 6  ISOST3GAL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Dyskeratosis congenita and autosomal dominant 6ClinVarPMID:28492532
St3gal2RatCharcot-Marie-Tooth disease type 2  ISOST3GAL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease type 2ClinVarPMID:28492532
St3gal2RatChromosome 16q12 Duplication Syndrome  ISOST3GAL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 16q12 duplication syndromeClinVarPMID:25741868
St3gal2Ratcongenital disorder of glycosylation type IIj  ISOST3GAL2 (Homo sapiens)8554872ClinVar Annotator: match by term: COG4-CDGClinVarPMID:19494034

1 to 20 of 81 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
St3gal2Rat1,1-dichloroethene increases expressionISOSt3gal2 (Mus musculus)6480464vinylidene chloride results in increased expression of ST3GAL2 mRNACTDPMID:26682919
St3gal2Rat1,2-dimethylhydrazine increases expressionISOSt3gal2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of ST3GAL2 mRNACTDPMID:22206623
St3gal2Rat17beta-estradiol increases expressionISOST3GAL2 (Homo sapiens)6480464Estradiol results in increased expression of ST3GAL2 mRNACTDPMID:19429434
St3gal2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of ST3GAL2 mRNACTDPMID:22298810
St3gal2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of ST3GAL2 mRNACTDPMID:33387578
St3gal2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSt3gal2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ST3GAL2 mRNACTDPMID:21570461
St3gal2Rat3,4-methylenedioxymethamphetamine increases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ST3GAL2 mRNACTDPMID:30071829
St3gal2Rat4,4'-sulfonyldiphenol decreases methylationISOSt3gal2 (Mus musculus)6480464bisphenol S results in decreased methylation of ST3GAL2 exonCTDPMID:33297965
St3gal2Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ST3GAL2 mRNACTDPMID:36041667
St3gal2Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of ST3GAL2 mRNACTDPMID:24780913
St3gal2Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of ST3GAL2 mRNACTDPMID:28959563
St3gal2Rataflatoxin B1 decreases methylationISOST3GAL2 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of ST3GAL2 intronCTDPMID:30157460
St3gal2Ratall-trans-retinoic acid increases expressionISOST3GAL2 (Homo sapiens)6480464Tretinoin results in increased expression of ST3GAL2 mRNACTDPMID:33167477
St3gal2Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of ST3GAL2 mRNACTDPMID:16483693
St3gal2Ratarsane affects methylationISOST3GAL2 (Homo sapiens)6480464Arsenic affects the methylation of ST3GAL2 geneCTDPMID:25304211
St3gal2Ratarsenic atom affects methylationISOST3GAL2 (Homo sapiens)6480464Arsenic affects the methylation of ST3GAL2 geneCTDPMID:25304211
St3gal2Ratarsenous acid decreases expressionISOST3GAL2 (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of ST3GAL2 mRNACTDPMID:20458559
St3gal2Ratarsenous acid increases expressionISOSt3gal2 (Mus musculus)6480464Arsenic Trioxide results in increased expression of ST3GAL2 mRNACTDPMID:29095437
St3gal2Ratarsenous acid increases expressionISOST3GAL2 (Homo sapiens)6480464Arsenic Trioxide results in increased expression of ST3GAL2 mRNACTDPMID:20458559
St3gal2Ratarsenous acid multiple interactionsISOSt3gal2 (Mus musculus)6480464Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of ST3GAL2 mRNA]CTDPMID:29095437

1 to 20 of 81 rows

Biological Process
1 to 20 of 30 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
St3gal2Ratganglioside biosynthetic process via lactosylceramide involved_inISOSt3gal2 (Mus musculus)1624291 PMID:22735313 and PMID:8144500RGDPMID:22735313 and PMID:8144500
St3gal2Ratganglioside biosynthetic process via lactosylceramide involved_inIEAUniProtKB:Q11204 and ensembl:ENSMUSP000000341971600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratganglioside biosynthetic process via lactosylceramide involved_inIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratganglioside biosynthetic process via lactosylceramide involved_inIBAMGI:98304 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
St3gal2Ratganglioside biosynthetic process via lactosylceramide involved_inIEAARBA:ARBA000434381600115GO_REF:0000117UniProtGO_REF:0000117
St3gal2Ratganglioside biosynthetic process via lactosylceramide involved_inISOST3GAL2 (Homo sapiens)1624291 PMID:8920913RGDPMID:8920913
St3gal2Ratganglioside biosynthetic process via lactosylceramide involved_inIDA 68307PMID:8144500UniProt 
St3gal2Ratgloboside biosynthetic process via lactosylceramide involved_inISSUniProtKB:Q168421600115GO_REF:0000024UniProtGO_REF:0000024
St3gal2Ratgloboside biosynthetic process via lactosylceramide involved_inISOST3GAL2 (Homo sapiens)1624291 PMID:12716912RGDPMID:12716912
St3gal2Ratgloboside biosynthetic process via lactosylceramide involved_inIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratglycolipid biosynthetic process involved_inISOST3GAL2 (Homo sapiens)1624291 PMID:9266697RGDPMID:9266697
St3gal2Ratglycolipid biosynthetic process involved_inIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratglycoprotein biosynthetic process involved_inISOST3GAL2 (Homo sapiens)1624291 PMID:9266697RGDPMID:9266697
St3gal2Ratglycoprotein biosynthetic process involved_inIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratlipid glycosylation involved_inISOST3GAL2 (Homo sapiens)1624291 PMID:9266697RGDPMID:9266697
St3gal2Ratlipid glycosylation involved_inIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
St3gal2Ratoligosaccharide biosynthetic process involved_inIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratoligosaccharide biosynthetic process involved_inISOST3GAL2 (Homo sapiens)1624291 PMID:9266697RGDPMID:9266697
St3gal2Ratprotein glycosylation involved_inIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 30 rows

Cellular Component
1 to 9 of 9 rows

  
Object Symbol
Species
Term
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Evidence
With
Reference
Notes
Source
Original Reference(s)
St3gal2Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
St3gal2Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
St3gal2RatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
St3gal2RatGolgi cisterna membrane located_inIEAUniProtKB-SubCell:SL-01361600115GO_REF:0000044UniProtGO_REF:0000044
St3gal2RatGolgi membrane located_inISSUniProtKB:Q168421600115GO_REF:0000024UniProtGO_REF:0000024
St3gal2RatGolgi membrane located_inIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2RatGolgi membrane located_inISOST3GAL2 (Homo sapiens)1624291 PMID:25916169RGDPMID:25916169
St3gal2Ratmembrane is_active_inIBAPANTHER:PTN000346261 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
St3gal2Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
1 to 9 of 9 rows

Molecular Function
1 to 18 of 18 rows

  
Object Symbol
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Term
Qualifier
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Reference
Notes
Source
Original Reference(s)
St3gal2Ratbeta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase enablesISOST3GAL2 (Homo sapiens)1624291 PMID:9266697RGDPMID:9266697
St3gal2Ratbeta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase enablesIEARHEA:180211600115GO_REF:0000116RHEAGO_REF:0000116
St3gal2Ratbeta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase enablesIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratbeta-galactoside (CMP) alpha-2,3-sialyltransferase activity enablesISOST3GAL2 (Homo sapiens)1624291 PMID:12716912 more ...RGDPMID:12716912 more ...
St3gal2Ratbeta-galactoside (CMP) alpha-2,3-sialyltransferase activity enablesIEAUniProtKB:Q11204 and ensembl:ENSMUSP000000341971600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratbeta-galactoside (CMP) alpha-2,3-sialyltransferase activity enablesIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratbeta-galactoside (CMP) alpha-2,3-sialyltransferase activity enablesISOSt3gal2 (Mus musculus)1624291 PMID:8144500 and PMID:9184827RGDPMID:8144500 and PMID:9184827
St3gal2Ratbeta-galactoside (CMP) alpha-2,3-sialyltransferase activity enablesIBAMGI:98304 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
St3gal2Ratbeta-galactoside (CMP) alpha-2,3-sialyltransferase activity enablesIEARHEA:216161600115GO_REF:0000116RHEAGO_REF:0000116
St3gal2Ratbeta-galactoside (CMP) alpha-2,3-sialyltransferase activity enablesIEAARBA:ARBA000433511600115GO_REF:0000117UniProtGO_REF:0000117
St3gal2Ratbeta-galactoside (CMP) alpha-2,3-sialyltransferase activity enablesIDA 68307PMID:8144500UniProt 
St3gal2Ratglycosyltransferase activity enablesIEAUniProtKB-KW:KW-03281600115GO_REF:0000043UniProtGO_REF:0000043
St3gal2Ratprotein homodimerization activity enablesISSUniProtKB:Q168421600115GO_REF:0000024UniProtGO_REF:0000024
St3gal2Ratprotein homodimerization activity enablesIEAUniProtKB:Q16842 and ensembl:ENSP000003454771600115GO_REF:0000107EnsemblGO_REF:0000107
St3gal2Ratprotein homodimerization activity enablesISOST3GAL2 (Homo sapiens)1624291 PMID:25916169RGDPMID:25916169
St3gal2Ratsialyltransferase activity  IDA 68307 RGD 
St3gal2Ratsialyltransferase activity enablesIEAInterPro:IPR001675 and InterPro:IPR0121631600115GO_REF:0000002InterProGO_REF:0000002
St3gal2Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
1 to 18 of 18 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
St3gal2Ratganglioside metabolic pathway  IEA 6907045 KEGGrno:00604
St3gal2Ratgloboside metabolic pathway  IEA 6907045 KEGGrno:00603
St3gal2Ratkeratan sulfate biosynthetic pathway  IEA 6907045 KEGGrno:00533
St3gal2RatO-linked glycan biosynthetic pathway  IEA 6907045 KEGGrno:00512

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning and expression of cDNA for a new type of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase. Lee YC, etal., J Biol Chem 1994 Apr 1;269(13):10028-33.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
PMID:9184827   PMID:9266697   PMID:21913655  



St3gal2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,798,112 - 55,849,226 (+)NCBIGRCr8
mRatBN7.21938,888,851 - 38,939,874 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,923,999 - 38,939,869 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1945,728,513 - 45,744,388 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,381,856 - 46,397,731 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01948,692,765 - 48,708,643 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01943,273,251 - 43,324,265 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1943,274,493 - 43,290,363 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01954,101,504 - 54,152,583 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,873,202 - 40,889,072 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,892,278 - 40,892,994 (-)NCBI
Celera1938,316,282 - 38,332,162 (+)NCBICelera
Cytogenetic Map19q12NCBI
ST3GAL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381670,375,977 - 70,439,100 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1670,375,977 - 70,439,237 (-)EnsemblGRCh38hg38GRCh38
GRCh371670,409,880 - 70,473,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361668,970,839 - 69,030,492 (-)NCBINCBI36Build 36hg18NCBI36
Build 341668,972,809 - 69,030,492NCBI
Celera1655,055,306 - 55,114,849 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1656,246,172 - 56,305,216 (-)NCBIHuRef
CHM1_11671,820,818 - 71,880,362 (-)NCBICHM1_1
T2T-CHM13v2.01676,187,004 - 76,250,128 (-)NCBIT2T-CHM13v2.0
St3gal2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398111,646,520 - 111,699,132 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8111,646,554 - 111,699,112 (+)EnsemblGRCm39 Ensembl
GRCm388110,919,743 - 110,974,058 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8110,919,922 - 110,972,480 (+)EnsemblGRCm38mm10GRCm38
MGSCv378113,443,765 - 113,496,397 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368113,806,599 - 113,858,234 (+)NCBIMGSCv36mm8
Celera8115,180,767 - 115,196,505 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map857.81NCBI
St3gal2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554843,177,104 - 3,230,433 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554843,176,214 - 3,230,433 (-)NCBIChiLan1.0ChiLan1.0
ST3GAL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21883,726,255 - 83,789,200 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11689,655,506 - 89,715,192 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01654,577,578 - 54,637,626 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11670,218,738 - 70,240,162 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1670,218,748 - 70,240,162 (-)Ensemblpanpan1.1panPan2
ST3GAL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1576,377,782 - 76,427,998 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl576,379,702 - 76,394,525 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha576,339,604 - 76,389,857 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0576,814,457 - 76,864,970 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl576,796,878 - 76,864,417 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1576,636,437 - 76,687,020 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0576,459,670 - 76,510,167 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0576,951,528 - 77,002,224 (-)NCBIUU_Cfam_GSD_1.0
St3gal2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934936,385,195 - 36,439,669 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647523,149,487 - 23,205,027 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647523,149,452 - 23,203,919 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST3GAL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl613,402,345 - 13,419,378 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1613,402,336 - 13,456,495 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ST3GAL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1553,530,077 - 53,585,065 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl553,531,781 - 53,545,739 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604716,316,291 - 16,376,499 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St3gal2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474612,623,730 - 12,680,436 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474612,623,966 - 12,680,430 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in St3gal2
48 total Variants

Predicted Target Of
Summary Value
Count of predictions:870
Count of miRNA genes:291
Interacting mature miRNAs:384
Transcripts:ENSRNOT00000024248
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat

1 to 10 of 16 rows
BF387076  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,938,311 - 38,938,468 (-)MAPPERmRatBN7.2
Rnor_6.01943,275,894 - 43,276,050NCBIRnor6.0
Rnor_5.01954,104,147 - 54,104,303UniSTSRnor5.0
RGSC_v3.41940,887,515 - 40,887,671UniSTSRGSC3.4
Celera1938,330,605 - 38,330,761UniSTS
RH 3.4 Map19474.0UniSTS
Cytogenetic Map19q12UniSTS
RH139813  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,939,013 - 38,939,204 (-)MAPPERmRatBN7.2
Rnor_6.01943,275,158 - 43,275,348NCBIRnor6.0
Rnor_5.01954,103,411 - 54,103,601UniSTSRnor5.0
RGSC_v3.41940,888,217 - 40,888,407UniSTSRGSC3.4
Celera1938,331,307 - 38,331,497UniSTS
RH 3.4 Map19481.5UniSTS
Cytogenetic Map19q12UniSTS
RH140953  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,939,596 - 38,939,782 (-)MAPPERmRatBN7.2
Rnor_6.01943,274,580 - 43,274,765NCBIRnor6.0
Rnor_5.01954,102,833 - 54,103,018UniSTSRnor5.0
RGSC_v3.41940,888,800 - 40,888,985UniSTSRGSC3.4
Celera1938,331,890 - 38,332,075UniSTS
RH 3.4 Map19478.1UniSTS
RH 3.4 Map19477.8UniSTS
Cytogenetic Map19q12UniSTS
AA850466  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,939,565 - 38,939,782 (-)MAPPERmRatBN7.2
Rnor_6.01943,274,580 - 43,274,796NCBIRnor6.0
Rnor_5.01954,102,833 - 54,103,049UniSTSRnor5.0
RGSC_v3.41940,888,769 - 40,888,985UniSTSRGSC3.4
Celera1938,331,859 - 38,332,075UniSTS
RH 3.4 Map19477.9UniSTS
Cytogenetic Map19q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000024248   ⟹   ENSRNOP00000024248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,923,999 - 38,939,869 (+)Ensembl
Rnor_6.0 Ensembl1943,274,493 - 43,290,363 (-)Ensembl
RefSeq Acc Id: NM_031695   ⟹   NP_113883
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,833,356 - 55,849,226 (+)NCBI
mRatBN7.21938,923,999 - 38,939,869 (+)NCBI
Rnor_6.01943,274,493 - 43,290,363 (-)NCBI
Rnor_5.01954,101,504 - 54,152,583 (-)NCBI
RGSC_v3.41940,873,202 - 40,889,072 (+)RGD
Celera1938,316,282 - 38,332,162 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255625   ⟹   XP_006255687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,799,446 - 55,848,734 (+)NCBI
mRatBN7.21938,890,065 - 38,939,874 (+)NCBI
Rnor_6.01943,273,251 - 43,324,265 (-)NCBI
Rnor_5.01954,101,504 - 54,152,583 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006255626   ⟹   XP_006255688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,799,447 - 55,848,734 (+)NCBI
mRatBN7.21938,890,065 - 38,939,874 (+)NCBI
Rnor_6.01943,273,251 - 43,324,265 (-)NCBI
Rnor_5.01954,101,504 - 54,152,583 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006255627   ⟹   XP_006255689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,799,441 - 55,848,734 (+)NCBI
mRatBN7.21938,890,065 - 38,939,874 (+)NCBI
Rnor_6.01943,273,251 - 43,324,265 (-)NCBI
Rnor_5.01954,101,504 - 54,152,583 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097961   ⟹   XP_038953889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,798,112 - 55,848,734 (+)NCBI
mRatBN7.21938,888,851 - 38,939,874 (+)NCBI
RefSeq Acc Id: XM_039097962   ⟹   XP_038953890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,833,623 - 55,848,734 (+)NCBI
mRatBN7.21938,924,274 - 38,939,874 (+)NCBI
RefSeq Acc Id: NP_113883   ⟸   NM_031695
- UniProtKB: Q11205 (UniProtKB/Swiss-Prot),   G3V8B2 (UniProtKB/TrEMBL),   A6IZ75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255689   ⟸   XM_006255627
- Peptide Label: isoform X1
- UniProtKB: Q11205 (UniProtKB/Swiss-Prot),   G3V8B2 (UniProtKB/TrEMBL),   A6IZ75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255687   ⟸   XM_006255625
- Peptide Label: isoform X1
- UniProtKB: Q11205 (UniProtKB/Swiss-Prot),   G3V8B2 (UniProtKB/TrEMBL),   A6IZ75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255688   ⟸   XM_006255626
- Peptide Label: isoform X1
- UniProtKB: Q11205 (UniProtKB/Swiss-Prot),   G3V8B2 (UniProtKB/TrEMBL),   A6IZ75 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024248   ⟸   ENSRNOT00000024248

Name Modeler Protein Id AA Range Protein Structure
AF-Q11205-F1-model_v2 AlphaFold Q11205 1-350 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-5671 BioCyc
BioCyc Pathway PWY-7433 [mucin core 1 and core 2 O-glycosylation] BioCyc
BioCyc Pathway Image PWY-7433 BioCyc
Ensembl Genes ENSRNOG00000017932 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000024248 ENTREZGENE
Gene3D-CATH 3.90.1480.20 UniProtKB/Swiss-Prot
InterPro Beta-gal_alpha2-3_sialyltrans UniProtKB/Swiss-Prot
  Glyco_trans_29 UniProtKB/Swiss-Prot
  GT29-like_sf UniProtKB/Swiss-Prot
  Sialyl_trans UniProtKB/Swiss-Prot
KEGG Report rno:64442 UniProtKB/Swiss-Prot
NCBI Gene 64442 ENTREZGENE
PANTHER ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1 UniProtKB/Swiss-Prot
  CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2 UniProtKB/Swiss-Prot
Pfam Glyco_transf_29 UniProtKB/Swiss-Prot
PhenoGen St3gal2 PhenoGen
PIRSF Sialyl_trans UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017932 RatGTEx
TIGR TC205044
UniProt A6IZ75 ENTREZGENE, UniProtKB/TrEMBL
  G3V8B2 ENTREZGENE, UniProtKB/TrEMBL
  Q11205 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 St3gal2  ST3 beta-galactoside alpha-2,3-sialyltransferase 2  Siat4b  sialyltransferase 4B (beta-galactoside alpha-2,3-sialyltransferase)  Symbol and Name updated 1299863 APPROVED
2004-09-10 Siat4b  sialyltransferase 4B (beta-galactoside alpha-2,3-sialyltransferase)  Siat5  sialyltransferase 5  Symbol and Name updated 1299863 APPROVED
2002-06-10 Siat5  sialyltransferase 5      Name updated 70584 APPROVED

Note Type Note Reference
gene_expression mainly expressed in brain and liver 68307
gene_protein 350 amino acids 68307