Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ip6k3 | Rat | 17beta-estradiol | decreases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of IP6K3 mRNA | CTD | PMID:23019147 | Ip6k3 | Rat | 17beta-estradiol | multiple interactions | ISO | IP6K3 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of IP6K3 mRNA | CTD | PMID:30165855 | Ip6k3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of IP6K3 mRNA | CTD | PMID:20106945 | Ip6k3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of IP6K3 mRNA | CTD | PMID:32109520 and PMID:33387578 | Ip6k3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ip6k3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of IP6K3 mRNA | CTD | PMID:24680724 | Ip6k3 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Ip6k3 | Rat | aflatoxin B1 | affects expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of IP6K3 protein | CTD | PMID:20106945 | Ip6k3 | Rat | aflatoxin B1 | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of IP6K3 mRNA | CTD | PMID:21632981 more ... | Ip6k3 | Rat | aldehydo-D-glucose | multiple interactions | ISO | Ip6k3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of IP6K3 mRNA | CTD | PMID:37567420 | Ip6k3 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of IP6K3 mRNA | CTD | PMID:35163327 | Ip6k3 | Rat | aristolochic acid A | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of IP6K3 mRNA | CTD | PMID:33212167 | Ip6k3 | Rat | atrazine | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Atrazine results in increased expression of IP6K3 mRNA | CTD | PMID:22378314 | Ip6k3 | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of IP6K3 mRNA | CTD | PMID:36841081 | Ip6k3 | Rat | benzo[a]pyrene | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of IP6K3 mRNA | CTD | PMID:20106945 more ... | Ip6k3 | Rat | benzo[a]pyrene | affects methylation | ISO | IP6K3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of IP6K3 exon and Benzo(a)pyrene affects the methylation of IP6K3 promoter | CTD | PMID:27901495 | Ip6k3 | Rat | biphenyl-4-amine | decreases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | 4-biphenylamine results in decreased expression of IP6K3 mRNA | CTD | PMID:24857880 | Ip6k3 | Rat | bromoacetate | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | bromoacetate results in increased expression of IP6K3 mRNA | CTD | PMID:19753638 | Ip6k3 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of IP6K3 mRNA | CTD | PMID:33453195 | Ip6k3 | Rat | cantharidin | decreases expression | ISO | Ip6k3 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of IP6K3 mRNA | CTD | PMID:36907384 | Ip6k3 | Rat | carbon nanotube | increases expression | ISO | Ip6k3 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of IP6K3 mRNA | CTD | PMID:25554681 | Ip6k3 | Rat | cisplatin | multiple interactions | ISO | IP6K3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of IP6K3 mRNA | CTD | PMID:27392435 | Ip6k3 | Rat | cisplatin | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of IP6K3 mRNA | CTD | PMID:27392435 | Ip6k3 | Rat | cyclosporin A | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of IP6K3 mRNA | CTD | PMID:20106945 | Ip6k3 | Rat | D-glucose | multiple interactions | ISO | Ip6k3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of IP6K3 mRNA | CTD | PMID:37567420 | Ip6k3 | Rat | dorsomorphin | multiple interactions | ISO | IP6K3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ip6k3 | Rat | doxorubicin | decreases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of IP6K3 mRNA | CTD | PMID:29803840 | Ip6k3 | Rat | entinostat | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | entinostat results in increased expression of IP6K3 mRNA | CTD | PMID:27188386 | Ip6k3 | Rat | ethyl methanesulfonate | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of IP6K3 mRNA | CTD | PMID:23649840 | Ip6k3 | Rat | ethylparaben | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of IP6K3 mRNA | CTD | PMID:37690743 | Ip6k3 | Rat | fructose | multiple interactions | ISO | Ip6k3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of IP6K3 mRNA | CTD | PMID:37567420 | Ip6k3 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of IP6K3 mRNA | CTD | PMID:33387578 | Ip6k3 | Rat | glucose | multiple interactions | ISO | Ip6k3 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of IP6K3 mRNA | CTD | PMID:37567420 | Ip6k3 | Rat | GW 4064 | decreases expression | ISO | Ip6k3 (Mus musculus) | 6480464 | GW 4064 results in decreased expression of IP6K3 mRNA | CTD | PMID:26655953 | Ip6k3 | Rat | naphthalene | increases expression | ISO | Ip6k3 (Mus musculus) | 6480464 | naphthalene results in increased expression of IP6K3 mRNA | CTD | PMID:18978301 | Ip6k3 | Rat | ozone | multiple interactions | ISO | Ip6k3 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of IP6K3 mRNA | CTD | PMID:34911549 | Ip6k3 | Rat | paracetamol | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of IP6K3 mRNA | CTD | PMID:22230336 | Ip6k3 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of IP6K3 mRNA | CTD | PMID:33387578 | Ip6k3 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of IP6K3 mRNA | CTD | PMID:35163327 | Ip6k3 | Rat | phenylmercury acetate | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of IP6K3 mRNA | CTD | PMID:26272509 | Ip6k3 | Rat | phenylmercury acetate | multiple interactions | ISO | IP6K3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IP6K3 mRNA | CTD | PMID:27188386 | Ip6k3 | Rat | potassium dichromate | decreases expression | ISO | Ip6k3 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of IP6K3 mRNA | CTD | PMID:23608068 | Ip6k3 | Rat | SB 431542 | multiple interactions | ISO | IP6K3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Ip6k3 | Rat | sunitinib | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of IP6K3 mRNA | CTD | PMID:31533062 | Ip6k3 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of IP6K3 mRNA | CTD | PMID:33387578 | Ip6k3 | Rat | trichostatin A | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of IP6K3 mRNA | CTD | PMID:24935251 | Ip6k3 | Rat | triclosan | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Triclosan results in increased expression of IP6K3 mRNA | CTD | PMID:30510588 | Ip6k3 | Rat | triptonide | decreases expression | ISO | Ip6k3 (Mus musculus) | 6480464 | triptonide results in decreased expression of IP6K3 mRNA | CTD | PMID:33045310 | Ip6k3 | Rat | urethane | decreases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of IP6K3 mRNA | CTD | PMID:28818685 | Ip6k3 | Rat | valproic acid | decreases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of IP6K3 mRNA | CTD | PMID:29154799 | Ip6k3 | Rat | valproic acid | affects expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of IP6K3 mRNA | CTD | PMID:25979313 | Ip6k3 | Rat | valproic acid | increases expression | ISO | IP6K3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of IP6K3 mRNA | CTD | PMID:24935251 and PMID:26272509 | Ip6k3 | Rat | valproic acid | multiple interactions | ISO | IP6K3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IP6K3 mRNA | CTD | PMID:27188386 | |