Symbol:
Kcne5
Name:
potassium voltage-gated channel subfamily E regulatory subunit 5
RGD ID:
1583501
Description:
Predicted to enable potassium channel regulator activity and transmembrane transporter binding activity. Predicted to contribute to delayed rectifier potassium channel activity and voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Predicted to be involved in several processes, including cardiac muscle cell action potential involved in contraction; regulation of cardiac muscle cell membrane repolarization; and regulation of potassium ion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Orthologous to human KCNE5 (potassium voltage-gated channel subfamily E regulatory subunit 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
KCNE1-like; Kcne1l; LOC681190; potassium channel, voltage gated subfamily E regulatory beta subunit 5; potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 5; potassium voltage-gated channel subfamily E member 1-like protein; potassium voltage-gated channel subfamily E regulatory beta subunit 5; potassium voltage-gated channel, Isk-related family, member 1-like; similar to potassium voltage-gated channel, Isk-related family, member 1-like; voltage-gated potassium channel accessory subunit 5
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 110,727,234 - 110,727,849 (-) NCBI GRCr8 mRatBN7.2 X 105,930,398 - 105,931,013 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 105,930,398 - 105,931,013 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 108,068,193 - 108,068,808 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 111,567,368 - 111,567,983 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 109,133,664 - 109,134,279 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 113,583,844 - 113,584,459 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 113,583,844 - 113,584,459 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 112,033,789 - 112,034,404 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 36,243,961 - 36,244,576 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera X 105,344,535 - 105,345,150 (-) NCBI Celera Cytogenetic Map X q33 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Biological Process
atrial cardiac muscle cell action potential (IEA,ISO) biological_process (ND) cardiac muscle contraction (IEA,ISO) membrane repolarization during action potential (IBA) membrane repolarization during ventricular cardiac muscle cell action potential (IEA) monoatomic ion transport (IEA) negative regulation of potassium ion export across plasma membrane (IEA,ISO) negative regulation of potassium ion transmembrane transport (IEA,ISO) positive regulation of potassium ion transmembrane transport (IEA,ISO) potassium ion export across plasma membrane (IBA) regulation of atrial cardiac muscle cell membrane repolarization (IEA,ISO) regulation of heart contraction (IEA,ISO) regulation of heart rate by cardiac conduction (IBA,IEA,ISO) regulation of membrane repolarization (IEA,ISO) regulation of potassium ion transmembrane transport (IEA,ISO) regulation of ventricular cardiac muscle cell membrane repolarization (IBA,IEA,ISO) ventricular cardiac muscle cell action potential (IBA,IEA,ISO)
Kcne5 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 110,727,234 - 110,727,849 (-) NCBI GRCr8 mRatBN7.2 X 105,930,398 - 105,931,013 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 105,930,398 - 105,931,013 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 108,068,193 - 108,068,808 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 111,567,368 - 111,567,983 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 109,133,664 - 109,134,279 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 113,583,844 - 113,584,459 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 113,583,844 - 113,584,459 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 112,033,789 - 112,034,404 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 36,243,961 - 36,244,576 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera X 105,344,535 - 105,345,150 (-) NCBI Celera Cytogenetic Map X q33 NCBI
KCNE5 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 X 109,623,700 - 109,625,172 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl X 109,623,700 - 109,625,172 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 X 108,866,929 - 108,868,401 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 X 108,753,585 - 108,755,049 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 X 108,673,073 - 108,674,538 NCBI Celera X 109,346,567 - 109,348,031 (-) NCBI Celera Cytogenetic Map X q23 NCBI HuRef X 98,489,930 - 98,491,217 (-) NCBI HuRef CHM1_1 X 108,778,194 - 108,779,658 (-) NCBI CHM1_1 T2T-CHM13v2.0 X 108,071,490 - 108,072,962 (-) NCBI T2T-CHM13v2.0
Kcne5 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 X 141,087,749 - 141,089,194 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl X 141,087,748 - 141,089,290 (-) Ensembl GRCm39 Ensembl GRCm38 X 142,304,753 - 142,306,198 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl X 142,304,752 - 142,306,294 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 X 138,739,296 - 138,740,741 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 X 137,551,121 - 137,552,566 (-) NCBI MGSCv36 mm8 Celera X 126,300,230 - 126,301,675 (-) NCBI Celera Cytogenetic Map X F2 NCBI cM Map X 63.11 NCBI
Kcne5 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 NW_004955490 6,242,197 - 6,243,627 (+) NCBI ChiLan1.0 ChiLan1.0
KCNE5 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 X 109,114,032 - 109,115,971 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 X 109,117,636 - 109,119,108 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 X 98,731,109 - 98,732,575 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 X 109,201,428 - 109,202,890 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl X 109,202,320 - 109,202,748 (-) Ensembl panpan1.1 panPan2
KCNE5 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 X 82,844,188 - 82,845,641 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl X 82,845,064 - 82,846,083 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha X 68,922,748 - 68,924,125 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 X 84,494,588 - 84,496,047 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl X 84,495,468 - 84,495,884 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 X 81,971,600 - 81,973,057 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 X 83,665,901 - 83,667,358 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 X 83,494,598 - 83,495,963 (-) NCBI UU_Cfam_GSD_1.0
Kcne5 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 X 82,099,472 - 82,100,922 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936499 5,557,202 - 5,557,627 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936499 5,557,076 - 5,558,467 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
KCNE5 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl X 89,741,190 - 89,742,672 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 X 89,741,187 - 89,742,732 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 X 105,356,199 - 105,357,717 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
KCNE5 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 X 97,477,667 - 97,485,376 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl X 97,478,562 - 97,478,987 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666065 22,673,085 - 22,676,609 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Kcne5 (Heterocephalus glaber - naked mole-rat)
.
Predicted Target Of
Count of predictions: 45 Count of miRNA genes: 41 Interacting mature miRNAs: 45 Transcripts: ENSRNOT00000025923 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1598872 Memor14 Memory QTL 14 4.5 exploratory behavior trait (VT:0010471) difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678) X 93956491 138956491 Rat 1598856 Memor1 Memory QTL 1 1.9 exploratory behavior trait (VT:0010471) total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443) X 103312877 148312877 Rat 1598809 Memor15 Memory QTL 15 4.4 exploratory behavior trait (VT:0010471) difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678) X 103312877 148312877 Rat 738025 Stresp3 Stress response QTL 3 4.61 0.0066 stress-related behavior trait (VT:0010451) defensive burying - approach X 100567703 150256146 Rat 61430 Cia18 Collagen induced arthritis QTL 18 3.1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) X 14843113 120568734 Rat 61431 Cia19 Collagen induced arthritis QTL 19 4.4 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) X 65612192 120568734 Rat 738035 Stresp1 Stress response QTL 1 4.96 0.000011 stress-related behavior trait (VT:0010451) defensive burying - coping X 41304447 112935181 Rat 724551 Glom1 Glomerulus QTL 1 2.8 0.0004 kidney glomerulus morphology trait (VT:0005325) count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002) X 75294106 120294106 Rat 1598837 Memor13 Memory QTL 13 3.2 exploratory behavior trait (VT:0010471) difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678) X 41052407 146860749 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
10
49
111
86
87
56
25
56
6
212
95
93
45
52
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000025923 ⟹ ENSRNOP00000067483
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 105,930,398 - 105,931,013 (-) Ensembl Rnor_6.0 Ensembl X 113,583,844 - 113,584,459 (-) Ensembl
RefSeq Acc Id:
NM_001101003 ⟹ NP_001094473
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 110,727,234 - 110,727,849 (-) NCBI mRatBN7.2 X 105,930,398 - 105,931,013 (-) NCBI Rnor_6.0 X 113,583,844 - 113,584,459 (-) NCBI Rnor_5.0 X 112,033,789 - 112,034,404 (-) NCBI RGSC_v3.4 X 36,243,961 - 36,244,576 (+) RGD Celera X 105,344,535 - 105,345,150 (-) RGD
Sequence:
TTGCTTCCCCTTGTCCAGGGGGAAAGGTCAACGGCGTCCTGGAGCCTCCGTGCCACTCTCCAACAGCCATGAACTGCAGCGAGAGCCAACGGCTGCAAACCCTCTTGAACCGCTTGCTGCTGGAGCTG CATCATCGTGGCAACGCCAGCGGCCTCGGTGTCGGATCCGGCCCGAGCATGGGCATGGGGGTCGTCCCTGACCCTTTCGTGGGCCGTGAGGCGACCAGCGCCAAGGGTAACGATGCTTATCTCTACAT CCTACTCATCATGATCTTCTATGCTTGCCTAGCCGGAGGCCTCATCCTGGCCTACACTCGCTCCCGCAAGCTCGTCGAGGCCAAGGATGAGCCACCCCTGGCCTGTGTTGCCGAGCAGGAATGGGTCC CCACCGCCGTCGCATCTGCTGACCCGGAGAATGGCCAGGGCTTGCTGGGTGAGGGCAGCCACCAGCTCGCACCAGGGGCTCTGCCTGCATTGGCCCAGTGCGCTGAGAGGGTCTAGATTCGCTGCCCT CCTCATTTTGTTTATATCTGGGCCTGGCTCCCGCGTTTTTATTGCCTTTCCAAAGCTTGCTTTACCAGAGGCCCAGAAGATGATGAGCGGTCAGAACCCTTCAA
hide sequence
RefSeq Acc Id:
NP_001094473 ⟸ NM_001101003
- UniProtKB:
A5HKJ1 (UniProtKB/TrEMBL), M0RCZ4 (UniProtKB/TrEMBL)
- Sequence:
MNCSESQRLQTLLNRLLLELHHRGNASGLGVGSGPSMGMGVVPDPFVGREATSAKGNDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKDEPPLACVAEQEWVPTAVASADPENGQGLLGEGSHQL APGALPALAQCAERV
hide sequence
Ensembl Acc Id:
ENSRNOP00000067483 ⟸ ENSRNOT00000025923
RGD ID: 13701962
Promoter ID: EPDNEW_R12486
Type: initiation region
Name: Kcne5_1
Description: potassium voltage-gated channel subfamily E regulatory subunit5
SO ACC ID: SO:0000170
Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ )
Experiment Methods: Single-end sequencing.
Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 X 113,584,543 - 113,584,603 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-02-11
Kcne5
potassium voltage-gated channel subfamily E regulatory subunit 5
Kcne5
potassium channel, voltage gated subfamily E regulatory beta subunit 5
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2016-01-27
Kcne5
potassium channel, voltage gated subfamily E regulatory beta subunit 5
Kcne5
potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 5
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2015-01-26
Kcne5
potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 5
Kcne1l
KCNE1-like
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2012-01-17
Kcne1l
KCNE1-like
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2008-03-05
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like
LOC681190
similar to potassium voltage-gated channel, Isk-related family, member 1-like
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2006-11-19
LOC681190
similar to potassium voltage-gated channel, Isk-related family, member 1-like
Symbol and Name status set to provisional
70820
PROVISIONAL