Kcne5 (potassium voltage-gated channel subfamily E regulatory subunit 5) - Rat Genome Database

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Gene: Kcne5 (potassium voltage-gated channel subfamily E regulatory subunit 5) Rattus norvegicus
Analyze
Symbol: Kcne5
Name: potassium voltage-gated channel subfamily E regulatory subunit 5
RGD ID: 1583501
Description: Predicted to enable potassium channel regulator activity and transmembrane transporter binding activity. Predicted to contribute to delayed rectifier potassium channel activity and voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Predicted to be involved in several processes, including cardiac muscle cell action potential involved in contraction; regulation of cardiac muscle cell membrane repolarization; and regulation of potassium ion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Orthologous to human KCNE5 (potassium voltage-gated channel subfamily E regulatory subunit 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: KCNE1-like; Kcne1l; LOC681190; potassium channel, voltage gated subfamily E regulatory beta subunit 5; potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 5; potassium voltage-gated channel subfamily E member 1-like protein; potassium voltage-gated channel subfamily E regulatory beta subunit 5; potassium voltage-gated channel, Isk-related family, member 1-like; similar to potassium voltage-gated channel, Isk-related family, member 1-like; voltage-gated potassium channel accessory subunit 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X110,727,234 - 110,727,849 (-)NCBIGRCr8
mRatBN7.2X105,930,398 - 105,931,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX105,930,398 - 105,931,013 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX108,068,193 - 108,068,808 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X111,567,368 - 111,567,983 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X109,133,664 - 109,134,279 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X113,583,844 - 113,584,459 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX113,583,844 - 113,584,459 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X112,033,789 - 112,034,404 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X36,243,961 - 36,244,576 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX105,344,535 - 105,345,150 (-)NCBICelera
Cytogenetic MapXq33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcne5Ratautistic disorder  ISOKCNE5 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Kcne5Ratautosomal hemophilia A  ISOKCNE5 (Homo sapiens)8554872ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA AClinVarPMID:31690835
Kcne5RatBrugada syndrome  ISOKCNE5 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Kcne5RatBrugada syndrome  ISOKCNE5 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:18313602 more ...
Kcne5RatCharcot-Marie-Tooth disease type X  ISOKCNE5 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth Neuropathy XClinVarPMID:24528855 and PMID:28492532
Kcne5Ratfactor VIII deficiency  ISOKCNE5 (Homo sapiens)8554872ClinVar Annotator: match by term: Factor 8 deficiency and congenitalClinVarPMID:31690835
Kcne5RatSudden Unexpected Nocturnal Death Syndrome  ISOKCNE5 (Homo sapiens)8554872ClinVar Annotator: match by term: Sudden unexpected nocturnal death syndromeClinVarPMID:25741868 more ...
Kcne5Ratsyndromic X-linked intellectual disability Lubs type  ISOKCNE5 (Homo sapiens)8554872ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs typeClinVarPMID:25741868

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcne5Rat17beta-estradiol multiple interactionsISOKCNE5 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of KCNE5 mRNACTDPMID:30165855
Kcne5Rat17beta-estradiol decreases expressionISOKcne5 (Mus musculus)6480464Estradiol results in decreased expression of KCNE5 mRNACTDPMID:19484750
Kcne5Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of KCNE5 mRNACTDPMID:32109520
Kcne5Rat4,4'-sulfonyldiphenol increases methylationISOKCNE5 (Homo sapiens)6480464bisphenol S results in increased methylation of KCNE5 geneCTDPMID:31601247
Kcne5Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of KCNE5 mRNACTDPMID:24780913 and PMID:25825206
Kcne5Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of KCNE5 mRNACTDPMID:31881176
Kcne5Ratacrylamide affects expressionEXP 6480464Acrylamide affects the expression of KCNE5 mRNACTDPMID:28959563
Kcne5Ratamiodarone increases expressionISOKCNE5 (Homo sapiens)6480464Amiodarone results in increased expression of KCNE5 mRNACTDPMID:19774075
Kcne5Rataristolochic acid A increases expressionISOKCNE5 (Homo sapiens)6480464aristolochic acid I results in increased expression of KCNE5 mRNACTDPMID:33212167
Kcne5Ratatrazine increases expressionISOKCNE5 (Homo sapiens)6480464Atrazine results in increased expression of KCNE5 mRNACTDPMID:22378314
Kcne5Ratbenzo[a]pyrene affects methylationISOKCNE5 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of KCNE5 3' UTR more ...CTDPMID:27901495
Kcne5Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of KCNE5 mRNACTDPMID:25181051 and PMID:27178563
Kcne5Ratbisphenol A increases expressionISOKcne5 (Mus musculus)6480464bisphenol A results in increased expression of KCNE5 mRNACTDPMID:30951980
Kcne5Ratbisphenol A decreases methylationISOKcne5 (Mus musculus)6480464bisphenol A results in decreased methylation of KCNE5 promoterCTDPMID:27312807
Kcne5Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of KCNE5 geneCTDPMID:28505145
Kcne5Ratbisphenol F increases expressionISOKcne5 (Mus musculus)6480464bisphenol F results in increased expression of KCNE5 mRNACTDPMID:30951980
Kcne5Ratcarbamazepine affects expressionISOKCNE5 (Homo sapiens)6480464Carbamazepine affects the expression of KCNE5 mRNACTDPMID:25979313
Kcne5RatCGP 52608 multiple interactionsISOKCNE5 (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to KCNE5 gene]CTDPMID:28238834
Kcne5RatCuprizon decreases expressionEXP 6480464Cuprizone results in decreased expression of KCNE5 mRNACTDPMID:27523638
Kcne5Ratcyclosporin A decreases expressionISOKCNE5 (Homo sapiens)6480464Cyclosporine results in decreased expression of KCNE5 mRNACTDPMID:27989131

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Biological Process
1 to 20 of 32 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcne5Ratatrial cardiac muscle cell action potential involved_inISOKCNE5 (Homo sapiens)1624291 PMID:18313602RGDPMID:18313602
Kcne5Ratatrial cardiac muscle cell action potential involved_inIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107
Kcne5Ratbiological_process  ND 159840705/2013: no relevant rat dataRGD 
Kcne5Ratcardiac muscle contraction involved_inISOKCNE5 (Homo sapiens)1624291 PMID:18313602RGDPMID:18313602
Kcne5Ratcardiac muscle contraction involved_inIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107
Kcne5Ratmembrane repolarization during action potential involved_inIBAPANTHER:PTN001445835 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kcne5Ratmembrane repolarization during ventricular cardiac muscle cell action potential involved_inIEAGO:19022821600115GO_REF:0000108GOCGO_REF:0000108
Kcne5Ratmonoatomic ion transport involved_inIEAInterPro:IPR0003691600115GO_REF:0000002InterProGO_REF:0000002
Kcne5Ratnegative regulation of potassium ion export across plasma membrane involved_inISOKCNE5 (Homo sapiens)1624291 PMID:18313602RGDPMID:18313602
Kcne5Ratnegative regulation of potassium ion export across plasma membrane involved_inIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107
Kcne5Ratnegative regulation of potassium ion transmembrane transport involved_inISOKCNE5 (Homo sapiens)1624291 PMID:12324418 and PMID:18313602RGDPMID:12324418 and PMID:18313602
Kcne5Ratnegative regulation of potassium ion transmembrane transport involved_inIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107
Kcne5Ratpositive regulation of potassium ion transmembrane transport involved_inISOKCNE5 (Homo sapiens)1624291 PMID:12324418RGDPMID:12324418
Kcne5Ratpositive regulation of potassium ion transmembrane transport involved_inIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107
Kcne5Ratpotassium ion export across plasma membrane involved_inIBAPANTHER:PTN001445835 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kcne5Ratregulation of atrial cardiac muscle cell membrane repolarization involved_inISOKCNE5 (Homo sapiens)1624291 PMID:18313602RGDPMID:18313602
Kcne5Ratregulation of atrial cardiac muscle cell membrane repolarization involved_inIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107
Kcne5Ratregulation of heart contraction involved_inISOKCNE5 (Homo sapiens)1624291 PMID:18313602RGDPMID:18313602
Kcne5Ratregulation of heart contraction involved_inIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107
Kcne5Ratregulation of heart rate by cardiac conduction involved_inISOKCNE5 (Homo sapiens)1624291 PMID:18313602 and PMID:21493962RGDPMID:18313602 and PMID:21493962
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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Kcne5Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Kcne5Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Kcne5Ratmembrane located_inIEAInterPro:IPR0003691600115GO_REF:0000002InterProGO_REF:0000002
Kcne5Ratplasma membrane located_inIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107
Kcne5Ratplasma membrane located_inISOKCNE5 (Homo sapiens)1624291 PMID:20533308RGDPMID:20533308
Kcne5Ratvoltage-gated potassium channel complex part_ofISOKCNE5 (Homo sapiens)1624291 PMID:12324418 and PMID:21493962RGDPMID:12324418 and PMID:21493962
Kcne5Ratvoltage-gated potassium channel complex part_ofIBAMGI:1891123 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Kcne5Ratvoltage-gated potassium channel complex part_ofIEAUniProtKB:Q9UJ90 and ensembl:ENSP000003611731600115GO_REF:0000107EnsemblGO_REF:0000107

Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:12324418   PMID:18313602   PMID:20533308   PMID:21493962  



Kcne5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X110,727,234 - 110,727,849 (-)NCBIGRCr8
mRatBN7.2X105,930,398 - 105,931,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX105,930,398 - 105,931,013 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX108,068,193 - 108,068,808 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X111,567,368 - 111,567,983 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X109,133,664 - 109,134,279 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X113,583,844 - 113,584,459 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX113,583,844 - 113,584,459 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X112,033,789 - 112,034,404 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X36,243,961 - 36,244,576 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX105,344,535 - 105,345,150 (-)NCBICelera
Cytogenetic MapXq33NCBI
KCNE5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X109,623,700 - 109,625,172 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX109,623,700 - 109,625,172 (-)EnsemblGRCh38hg38GRCh38
GRCh37X108,866,929 - 108,868,401 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X108,753,585 - 108,755,049 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X108,673,073 - 108,674,538NCBI
CeleraX109,346,567 - 109,348,031 (-)NCBICelera
Cytogenetic MapXq23NCBI
HuRefX98,489,930 - 98,491,217 (-)NCBIHuRef
CHM1_1X108,778,194 - 108,779,658 (-)NCBICHM1_1
T2T-CHM13v2.0X108,071,490 - 108,072,962 (-)NCBIT2T-CHM13v2.0
Kcne5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X141,087,749 - 141,089,194 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX141,087,748 - 141,089,290 (-)EnsemblGRCm39 Ensembl
GRCm38X142,304,753 - 142,306,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX142,304,752 - 142,306,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X138,739,296 - 138,740,741 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X137,551,121 - 137,552,566 (-)NCBIMGSCv36mm8
CeleraX126,300,230 - 126,301,675 (-)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX63.11NCBI
Kcne5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554906,242,197 - 6,243,627 (+)NCBIChiLan1.0ChiLan1.0
KCNE5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X109,114,032 - 109,115,971 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X109,117,636 - 109,119,108 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X98,731,109 - 98,732,575 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X109,201,428 - 109,202,890 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX109,202,320 - 109,202,748 (-)Ensemblpanpan1.1panPan2
KCNE5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X82,844,188 - 82,845,641 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX82,845,064 - 82,846,083 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX68,922,748 - 68,924,125 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X84,494,588 - 84,496,047 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX84,495,468 - 84,495,884 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X81,971,600 - 81,973,057 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X83,665,901 - 83,667,358 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X83,494,598 - 83,495,963 (-)NCBIUU_Cfam_GSD_1.0
Kcne5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X82,099,472 - 82,100,922 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364995,557,202 - 5,557,627 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364995,557,076 - 5,558,467 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNE5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX89,741,190 - 89,742,672 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X89,741,187 - 89,742,732 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X105,356,199 - 105,357,717 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNE5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X97,477,667 - 97,485,376 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX97,478,562 - 97,478,987 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606522,673,085 - 22,676,609 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcne5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248036,385,405 - 6,385,876 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Kcne5
1 total Variants

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:41
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000025923
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat

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alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 49 111 86 87 56 25 56 6 212 95 93 45 52 31



Ensembl Acc Id: ENSRNOT00000025923   ⟹   ENSRNOP00000067483
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX105,930,398 - 105,931,013 (-)Ensembl
Rnor_6.0 EnsemblX113,583,844 - 113,584,459 (-)Ensembl
RefSeq Acc Id: NM_001101003   ⟹   NP_001094473
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X110,727,234 - 110,727,849 (-)NCBI
mRatBN7.2X105,930,398 - 105,931,013 (-)NCBI
Rnor_6.0X113,583,844 - 113,584,459 (-)NCBI
Rnor_5.0X112,033,789 - 112,034,404 (-)NCBI
RGSC_v3.4X36,243,961 - 36,244,576 (+)RGD
CeleraX105,344,535 - 105,345,150 (-)RGD
Sequence:
Protein RefSeqs NP_001094473 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABQ08565 (Get FASTA)   NCBI Sequence Viewer  
  EDL85209 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000067483
  ENSRNOP00000067483.1
RefSeq Acc Id: NP_001094473   ⟸   NM_001101003
- UniProtKB: A5HKJ1 (UniProtKB/TrEMBL),   M0RCZ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067483   ⟸   ENSRNOT00000025923

Name Modeler Protein Id AA Range Protein Structure
AF-A5HKJ1-F1-model_v2 AlphaFold A5HKJ1 1-143 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701962
Promoter ID:EPDNEW_R12486
Type:initiation region
Name:Kcne5_1
Description:potassium voltage-gated channel subfamily E regulatory subunit5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X113,584,543 - 113,584,603EPDNEW


1 to 14 of 14 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-1516 BioCyc
Ensembl Genes ENSRNOG00000019176 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025923 ENTREZGENE
  ENSRNOT00000025923.7 UniProtKB/TrEMBL
InterPro K_chnl_volt-dep_bsu_KCNE UniProtKB/TrEMBL
KEGG Report rno:681190 UniProtKB/TrEMBL
NCBI Gene 681190 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E REGULATORY BETA SUBUNIT 5 UniProtKB/TrEMBL
  PTHR15282 UniProtKB/TrEMBL
Pfam ISK_Channel UniProtKB/TrEMBL
PhenoGen Kcne5 PhenoGen
RatGTEx ENSRNOG00000019176 RatGTEx
UniProt A5HKJ1 ENTREZGENE, UniProtKB/TrEMBL
  M0RCZ4 ENTREZGENE, UniProtKB/TrEMBL
1 to 14 of 14 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Kcne5  potassium voltage-gated channel subfamily E regulatory subunit 5  Kcne5  potassium channel, voltage gated subfamily E regulatory beta subunit 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-27 Kcne5  potassium channel, voltage gated subfamily E regulatory beta subunit 5  Kcne5  potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-01-26 Kcne5  potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 5  Kcne1l  KCNE1-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-17 Kcne1l  KCNE1-like  Kcne1l  potassium voltage-gated channel, Isk-related family, member 1-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Kcne1l  potassium voltage-gated channel, Isk-related family, member 1-like  LOC681190  similar to potassium voltage-gated channel, Isk-related family, member 1-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC681190  similar to potassium voltage-gated channel, Isk-related family, member 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL