Stt3a (STT3 oligosaccharyltransferase complex catalytic subunit A) - Rat Genome Database

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Gene: Stt3a (STT3 oligosaccharyltransferase complex catalytic subunit A) Rattus norvegicus
Analyze
Symbol: Stt3a
Name: STT3 oligosaccharyltransferase complex catalytic subunit A
RGD ID: 1565793
Description: Predicted to enable dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in co-translational protein modification and protein N-linked glycosylation via asparagine. Predicted to be located in membrane. Predicted to be part of oligosaccharyltransferase III complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iw. Orthologous to human STT3A (STT3 oligosaccharyltransferase complex catalytic subunit A); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH 17beta-estradiol; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; integral membrane protein 1; integral transmembrane protein 1; integral transmembrane protein 1 (mapped); Itm1; Itm1_mapped; LOC500972; MGC188229; RGD1565793; similar to integral membrane protein 1; STT3, subunit of the oligosaccharyltransferase complex, homolog A; STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae); STT3A, catalytic subunit of the oligosaccharyltransferase complex; STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8844,632,473 - 44,671,960 (-)NCBIGRCr8
mRatBN7.2836,443,623 - 36,483,111 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl836,446,788 - 36,483,293 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx840,452,846 - 40,492,526 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0838,735,905 - 38,775,584 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0836,598,791 - 36,638,472 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,204,218 - 39,243,751 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,181,163 - 39,243,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,207,076 - 39,246,467 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4837,977,378 - 38,016,865 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera837,957,877 - 37,997,621 (+)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Molecular cloning of a highly conserved mouse and human integral membrane protein (Itm1) and genetic mapping to mouse chromosome 9. Hong G, etal., Genomics 1996 Feb 1;31(3):295-300.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12887896   PMID:14576154   PMID:19167329   PMID:19946888   PMID:22467853   PMID:24625528  


Genomics

Comparative Map Data
Stt3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8844,632,473 - 44,671,960 (-)NCBIGRCr8
mRatBN7.2836,443,623 - 36,483,111 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl836,446,788 - 36,483,293 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx840,452,846 - 40,492,526 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0838,735,905 - 38,775,584 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0836,598,791 - 36,638,472 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,204,218 - 39,243,751 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,181,163 - 39,243,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,207,076 - 39,246,467 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4837,977,378 - 38,016,865 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera837,957,877 - 37,997,621 (+)NCBICelera
Cytogenetic Map8q22NCBI
STT3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811125,591,769 - 125,623,091 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11125,591,712 - 125,625,215 (+)EnsemblGRCh38hg38GRCh38
GRCh3711125,462,747 - 125,492,986 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,967,967 - 124,996,168 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411124,967,966 - 124,996,162NCBI
Celera11122,623,051 - 122,651,590 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11121,404,246 - 121,434,022 (+)NCBIHuRef
CHM1_111125,348,849 - 125,378,778 (+)NCBICHM1_1
T2T-CHM13v2.011125,621,493 - 125,651,713 (+)NCBIT2T-CHM13v2.0
Stt3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39936,640,640 - 36,678,918 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl936,640,640 - 36,678,975 (-)EnsemblGRCm39 Ensembl
GRCm38936,729,344 - 36,767,622 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl936,729,344 - 36,767,679 (-)EnsemblGRCm38mm10GRCm38
MGSCv37936,539,998 - 36,575,163 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36936,481,044 - 36,517,312 (-)NCBIMGSCv36mm8
Celera933,935,517 - 33,969,930 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.67NCBI
Stt3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541226,595,666 - 26,623,621 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541226,593,142 - 26,624,143 (+)NCBIChiLan1.0ChiLan1.0
STT3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29126,281,427 - 126,309,692 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111127,385,891 - 127,417,605 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011120,412,488 - 120,440,713 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111124,325,388 - 124,353,598 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,325,762 - 124,353,596 (+)Ensemblpanpan1.1panPan2
STT3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,916,428 - 8,942,097 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,910,940 - 8,942,146 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha58,962,028 - 8,987,208 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,859,753 - 8,884,961 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,853,184 - 8,885,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.158,929,196 - 8,954,388 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,899,155 - 8,924,907 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.058,936,305 - 8,961,500 (-)NCBIUU_Cfam_GSD_1.0
Stt3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,728,232 - 107,754,350 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367431,975,847 - 2,000,100 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STT3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,724,441 - 52,754,669 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,726,794 - 52,754,671 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,380,053 - 58,407,896 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STT3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,734,393 - 116,762,820 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,734,393 - 116,762,231 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660439,307,922 - 9,336,325 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stt3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249271,577,534 - 1,606,596 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249271,577,504 - 1,608,328 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Stt3a
460 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:417
Count of miRNA genes:238
Interacting mature miRNAs:298
Transcripts:ENSRNOT00000043518
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82664491246711092Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)82824291253961020Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82950266550095447Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
70206Alc20Alcohol consumption QTL 202drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)83084815440713225Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815442692818Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat

Markers in Region
D8Got43  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2836,469,535 - 36,469,727 (+)MAPPERmRatBN7.2
Rnor_6.0839,230,130 - 39,230,321NCBIRnor6.0
Rnor_5.0839,232,847 - 39,233,038UniSTSRnor5.0
RGSC_v3.4838,003,289 - 38,003,481RGDRGSC3.4
RGSC_v3.4838,003,290 - 38,003,481UniSTSRGSC3.4
RGSC_v3.1838,012,056 - 38,012,247RGD
Celera837,971,264 - 37,971,457UniSTS
RH 3.4 Map8314.4UniSTS
RH 3.4 Map8314.4RGD
RH 2.0 Map8237.9RGD
Cytogenetic Map8q21UniSTS
RH143132  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2836,446,832 - 36,446,958 (+)MAPPERmRatBN7.2
Rnor_6.0839,207,427 - 39,207,552NCBIRnor6.0
Rnor_5.0839,210,285 - 39,210,410UniSTSRnor5.0
RGSC_v3.4837,980,587 - 37,980,712UniSTSRGSC3.4
Celera837,994,287 - 37,994,412UniSTS
RH 3.4 Map8314.4UniSTS
Cytogenetic Map8q21UniSTS
BE105951  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2836,446,831 - 36,446,998 (+)MAPPERmRatBN7.2
Rnor_6.0839,207,426 - 39,207,592NCBIRnor6.0
Rnor_5.0839,210,284 - 39,210,450UniSTSRnor5.0
RGSC_v3.4837,980,586 - 37,980,752UniSTSRGSC3.4
Celera837,994,247 - 37,994,413UniSTS
RH 3.4 Map8316.6UniSTS
Cytogenetic Map8q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 57 41 19 41 3 3 74 35 41 11 3
Low 11 5 8 5
Below cutoff

Sequence


RefSeq Acc Id: NM_001134749   ⟹   NP_001128221
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8844,632,473 - 44,671,960 (-)NCBI
mRatBN7.2836,443,623 - 36,483,111 (-)NCBI
Rnor_6.0839,204,218 - 39,243,705 (-)NCBI
Rnor_5.0839,207,076 - 39,246,467 (-)NCBI
RGSC_v3.4837,977,378 - 38,016,865 (-)RGD
Celera837,957,877 - 37,997,621 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001128221 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68223 (Get FASTA)   NCBI Sequence Viewer  
  EDL84046 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040087.5
  ENSRNOP00000076852.1
  ENSRNOP00000083682.1
  ENSRNOP00000097342
  ENSRNOP00000097342.1
RefSeq Acc Id: NP_001128221   ⟸   NM_001134749
- UniProtKB: B4F7C9 (UniProtKB/TrEMBL),   F1LM63 (UniProtKB/TrEMBL),   A6KRN0 (UniProtKB/TrEMBL)
- Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695856
Promoter ID:EPDNEW_R6379
Type:initiation region
Name:Chek1_1
Description:checkpoint kinase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6378  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0839,243,697 - 39,243,757EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565793 AgrOrtholog
BioCyc Gene G2FUF-31102 BioCyc
BioCyc Pathway MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS [protein N-glycosylation initial phase (eukaryotic)] BioCyc
BioCyc Pathway Image MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS BioCyc
Ensembl Genes ENSRNOG00000031896 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000043518.5 UniProtKB/TrEMBL
  ENSRNOT00000096876 ENTREZGENE
  ENSRNOT00000096876.1 UniProtKB/TrEMBL
  ENSRNOT00000103971.1 UniProtKB/TrEMBL
  ENSRNOT00000112569.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.12610 UniProtKB/TrEMBL
InterPro Oligo_trans_STT3 UniProtKB/TrEMBL
  STT3-PglB_core UniProtKB/TrEMBL
  STT3_N UniProtKB/TrEMBL
KEGG Report rno:500972 UniProtKB/TrEMBL
NCBI Gene 500972 ENTREZGENE
PANTHER DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A UniProtKB/TrEMBL
  PTHR13872 UniProtKB/TrEMBL
Pfam STT3 UniProtKB/TrEMBL
  STT3-PglB_core UniProtKB/TrEMBL
PhenoGen Stt3a PhenoGen
RatGTEx ENSRNOG00000031896 RatGTEx
UniProt A0A8I5Y525_RAT UniProtKB/TrEMBL
  A0A8I5ZX38_RAT UniProtKB/TrEMBL
  A0A8I6AND0_RAT UniProtKB/TrEMBL
  A0A8J8YL51_RAT UniProtKB/TrEMBL
  A6KRN0 ENTREZGENE, UniProtKB/TrEMBL
  B4F7C9 ENTREZGENE, UniProtKB/TrEMBL
  F1LM63 ENTREZGENE
UniProt Secondary F1LM63 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 Stt3a  STT3 oligosaccharyltransferase complex catalytic subunit A  Stt3a  STT3A, catalytic subunit of the oligosaccharyltransferase complex  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-19 Stt3a  STT3A, catalytic subunit of the oligosaccharyltransferase complex  Stt3a  STT3A, subunit of the oligosaccharyltransferase complex (catalytic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-20 Stt3a  STT3A, subunit of the oligosaccharyltransferase complex (catalytic)  Stt3a  STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-15 Stt3a  STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)  Itm1_mapped  integral transmembrane protein 1 (mapped)  Data merged from RGD:2930 1643240 APPROVED
2008-03-07 Stt3a  STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)  Stt3a_predicted  similar to integral membrane protein 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-24 Stt3a_predicted    RGD1565793_predicted  similar to integral membrane protein 1 (predicted)  Symbol updated 737654 APPROVED
2007-04-24 RGD1565793_predicted  similar to integral membrane protein 1 (predicted)  Itm1_mapped  integral transmembrane protein 1 (mapped)  Data merged from RGD:2930 737654 APPROVED
2006-03-07 RGD1565793_predicted  similar to integral membrane protein 1 (predicted)  LOC500972  similar to integral membrane protein 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500972  similar to integral membrane protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Itm1_mapped  integral transmembrane protein 1 (mapped)  Itm1  integral membrane protein 1  Symbol and Name updated 1556543 APPROVED
2005-07-14 Itm1  integral membrane protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-03-04   integral membrane protein 1  Itm1  intergral membrane protein 1  Name updated 1299863 APPROVED
2002-06-10 Itm1  Integral transmembrane protein 1      Symbol and Name status set to approved 70586 APPROVED