Bank1 (B-cell scaffold protein with ankyrin repeats 1) - Rat Genome Database

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Gene: Bank1 (B-cell scaffold protein with ankyrin repeats 1) Rattus norvegicus
Analyze
Symbol: Bank1
Name: B-cell scaffold protein with ankyrin repeats 1
RGD ID: 1564639
Description: Predicted to enable enzyme binding activity; signaling adaptor activity; and signaling receptor binding activity. Predicted to be involved in several processes, including negative regulation of B cell activation; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to act upstream of or within negative regulation of gene expression; positive regulation of MAPK cascade; and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autoimmune disease (multiple) and systemic scleroderma (multiple). Orthologous to human BANK1 (B cell scaffold protein with ankyrin repeats 1); INTERACTS WITH acetamide; alpha-Zearalanol; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B-cell scaffold protein with ankyrin repeats; hypothetical protein LOC365948; LOC365948; LRRGT00104; similar to AVIEF
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82227,203,998 - 227,474,008 (-)NCBIGRCr8
mRatBN7.22224,530,475 - 224,800,420 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2224,530,475 - 224,800,405 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2232,261,483 - 232,551,659 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02230,161,220 - 230,451,396 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02225,025,817 - 225,316,021 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02241,273,763 - 241,545,527 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2241,273,763 - 241,545,250 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02259,830,423 - 260,099,770 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42233,471,600 - 233,747,012 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2216,725,955 - 216,996,655 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Kozyrev SV, etal., Nat Genet. 2008 Feb;40(2):211-6. doi: 10.1038/ng.79. Epub 2008 Jan 20.
3. Genetic variants of BANK1 gene in autoimmune thyroid diseases: a case-control association study. Muhali FS, etal., Exp Clin Endocrinol Diabetes. 2013 Oct;121(9):556-60. doi: 10.1055/s-0033-1348220. Epub 2013 Oct 14.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians. Rueda B, etal., Ann Rheum Dis. 2010 Apr;69(4):700-5. doi: 10.1136/ard.2009.118174. Epub 2009 Oct 8.
9. Association analysis of BANK1 gene with psoriasis in Southern Han Chinese. Zhang X, etal., Int J Immunogenet. 2011 Dec;38(6):507-12. doi: 10.1111/j.1744-313X.2011.01045.x. Epub 2011 Oct 12.
10. Association of BANK1 and cytokine gene polymorphisms with type 1 diabetes in Tunisia. Zouidi F, etal., Gene. 2014 Feb 25;536(2):296-301. doi: 10.1016/j.gene.2013.12.008. Epub 2013 Dec 14.
Additional References at PubMed
PMID:11782428   PMID:16546095   PMID:23012479   PMID:24227780   PMID:31965814  


Genomics

Comparative Map Data
Bank1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82227,203,998 - 227,474,008 (-)NCBIGRCr8
mRatBN7.22224,530,475 - 224,800,420 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2224,530,475 - 224,800,405 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2232,261,483 - 232,551,659 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02230,161,220 - 230,451,396 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02225,025,817 - 225,316,021 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02241,273,763 - 241,545,527 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2241,273,763 - 241,545,250 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02259,830,423 - 260,099,770 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42233,471,600 - 233,747,012 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2216,725,955 - 216,996,655 (-)NCBICelera
Cytogenetic Map2q43NCBI
BANK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384101,790,730 - 102,074,812 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4101,411,286 - 102,074,812 (+)EnsemblGRCh38hg38GRCh38
GRCh374102,711,887 - 102,995,969 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364102,930,787 - 103,214,992 (+)NCBINCBI36Build 36hg18NCBI36
Build 344103,069,073 - 103,353,073NCBI
Celera4100,010,928 - 100,294,453 (+)NCBICelera
Cytogenetic Map4q24NCBI
HuRef498,449,206 - 98,733,393 (+)NCBIHuRef
CHM1_14102,688,233 - 102,972,393 (+)NCBICHM1_1
T2T-CHM13v2.04105,104,977 - 105,389,016 (+)NCBIT2T-CHM13v2.0
Bank1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393135,759,124 - 136,031,902 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3135,759,124 - 136,031,827 (-)EnsemblGRCm39 Ensembl
GRCm383136,053,363 - 136,326,141 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3136,053,363 - 136,326,066 (-)EnsemblGRCm38mm10GRCm38
MGSCv373135,716,327 - 135,989,010 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363135,990,753 - 136,263,442 (-)NCBIMGSCv36mm8
Celera3142,477,189 - 142,751,960 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map363.04NCBI
Bank1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554966,267,551 - 6,470,948 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554966,267,618 - 6,511,195 (-)NCBIChiLan1.0ChiLan1.0
BANK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2399,875,994 - 100,169,841 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14100,162,614 - 100,456,615 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0494,216,751 - 94,507,965 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14104,882,347 - 105,172,593 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4104,813,791 - 105,171,527 (+)Ensemblpanpan1.1panPan2
BANK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13223,322,654 - 23,603,233 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3223,323,122 - 23,602,383 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3218,421,676 - 18,467,573 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03223,542,873 - 23,823,010 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3223,542,975 - 23,822,801 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13223,520,939 - 23,802,176 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03223,303,072 - 23,582,811 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03216,282,026 - 16,562,365 (-)NCBIUU_Cfam_GSD_1.0
Bank1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530117,864,623 - 18,132,874 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365201,193,850 - 1,476,279 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365201,207,078 - 1,284,679 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BANK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8118,814,061 - 119,157,504 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18118,814,352 - 119,114,973 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28128,228,842 - 128,321,122 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BANK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1749,910,851 - 50,205,524 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl749,911,393 - 50,204,476 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603728,393,744 - 28,703,036 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bank1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248305,732,384 - 6,023,665 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248305,733,435 - 6,068,349 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bank1
2204 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:81
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000051498, ENSRNOT00000073875
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1359019Hrtrt19Heart rate QTL 192.9heart pumping trait (VT:2000009)heart rate (CMO:0000002)2219753301226277316Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat

Markers in Region
D2Rat293  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22224,786,940 - 224,787,090 (+)MAPPERmRatBN7.2
Rnor_6.02241,531,986 - 241,532,137NCBIRnor6.0
Rnor_5.02260,086,506 - 260,086,657UniSTSRnor5.0
RGSC_v3.42233,733,747 - 233,733,899RGDRGSC3.4
RGSC_v3.42233,733,748 - 233,733,899UniSTSRGSC3.4
RGSC_v3.12233,720,487 - 233,720,639RGD
Celera2216,983,391 - 216,983,542UniSTS
RH 3.4 Map21570.1RGD
RH 3.4 Map21570.1UniSTS
RH 2.0 Map21125.8RGD
SHRSP x BN Map296.5398RGD
Cytogenetic Map2q43UniSTS
D2Got357  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22224,792,464 - 224,792,736 (+)MAPPERmRatBN7.2
Rnor_6.02241,537,512 - 241,537,783NCBIRnor6.0
Rnor_5.02260,092,032 - 260,092,303UniSTSRnor5.0
RGSC_v3.42233,739,274 - 233,739,545UniSTSRGSC3.4
Celera2216,988,917 - 216,989,188UniSTS
Cytogenetic Map2q43UniSTS
RH140009  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22224,530,943 - 224,531,138 (+)MAPPERmRatBN7.2
Rnor_6.02241,274,232 - 241,274,426NCBIRnor6.0
Rnor_5.02259,830,892 - 259,831,086UniSTSRnor5.0
RGSC_v3.42233,471,628 - 233,471,822UniSTSRGSC3.4
Celera2216,726,424 - 216,726,618UniSTS
RH 3.4 Map21570.4UniSTS
Cytogenetic Map2q43UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 4 15 1 10
Low 1 39 28 4 28 4 12 1
Below cutoff 22 14 13 13 8 8 29 23 16 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000051498   ⟹   ENSRNOP00000040020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2224,700,143 - 224,730,655 (-)Ensembl
Rnor_6.0 Ensembl2241,442,228 - 241,472,694 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000073875   ⟹   ENSRNOP00000066483
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2224,530,475 - 224,762,151 (-)Ensembl
Rnor_6.0 Ensembl2241,273,763 - 241,545,250 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100656   ⟹   ENSRNOP00000092966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2224,530,475 - 224,800,405 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105974   ⟹   ENSRNOP00000083548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2224,530,475 - 224,800,405 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106727   ⟹   ENSRNOP00000096931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2224,530,475 - 224,800,203 (-)Ensembl
RefSeq Acc Id: NM_001047918   ⟹   NP_001041383
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82227,203,998 - 227,473,715 (-)NCBI
mRatBN7.22224,530,475 - 224,800,203 (-)NCBI
Rnor_6.02241,273,763 - 241,545,250 (-)NCBI
Rnor_5.02259,830,423 - 260,099,770 (-)NCBI
Celera2216,725,955 - 216,996,655 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591004   ⟹   XP_017446493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82227,203,998 - 227,474,008 (-)NCBI
mRatBN7.22224,530,475 - 224,800,420 (-)NCBI
Rnor_6.02241,273,763 - 241,545,527 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102804   ⟹   XP_038958732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82227,203,998 - 227,474,008 (-)NCBI
mRatBN7.22224,530,475 - 224,800,420 (-)NCBI
RefSeq Acc Id: XM_039102806   ⟹   XP_038958734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82227,203,998 - 227,473,927 (-)NCBI
mRatBN7.22224,530,475 - 224,800,420 (-)NCBI
RefSeq Acc Id: XM_039102807   ⟹   XP_038958735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82227,203,998 - 227,435,619 (-)NCBI
mRatBN7.22224,530,475 - 224,762,106 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001041383   ⟸   NM_001047918
- UniProtKB: A6HVZ2 (UniProtKB/TrEMBL),   A0A8I5ZZK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446493   ⟸   XM_017591004
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZZK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000040020   ⟸   ENSRNOT00000051498
RefSeq Acc Id: ENSRNOP00000066483   ⟸   ENSRNOT00000073875
RefSeq Acc Id: XP_038958734   ⟸   XM_039102806
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZZK5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958732   ⟸   XM_039102804
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AIR4 (UniProtKB/TrEMBL),   A0A8I5ZZK5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958735   ⟸   XM_039102807
- Peptide Label: isoform X4
- UniProtKB: M0RAD7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000092966   ⟸   ENSRNOT00000100656
RefSeq Acc Id: ENSRNOP00000096931   ⟸   ENSRNOT00000106727
RefSeq Acc Id: ENSRNOP00000083548   ⟸   ENSRNOT00000105974
Protein Domains
DBB   TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RAD7-F1-model_v2 AlphaFold M0RAD7 1-783 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691774
Promoter ID:EPDNEW_R2299
Type:single initiation site
Name:Bank1_1
Description:B-cell scaffold protein with ankyrin repeats 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02241,545,322 - 241,545,382EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564639 AgrOrtholog
BioCyc Gene G2FUF-51123 BioCyc
Ensembl Genes ENSRNOG00000032247 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000051498.2 UniProtKB/TrEMBL
  ENSRNOT00000073875.4 UniProtKB/TrEMBL
  ENSRNOT00000100656.1 UniProtKB/TrEMBL
  ENSRNOT00000105974 ENTREZGENE
  ENSRNOT00000105974.1 UniProtKB/TrEMBL
  ENSRNOT00000106727.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10140 UniProtKB/TrEMBL
InterPro Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  DBB_domain UniProtKB/TrEMBL
  PIK3AP1_TIR UniProtKB/TrEMBL
  TIR_dom UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
KEGG Report rno:365948 UniProtKB/TrEMBL
NCBI Gene 365948 ENTREZGENE
PANTHER B-CELL SCAFFOLD PROTEIN WITH ANKYRIN REPEATS UniProtKB/TrEMBL
  BANK1/PIK3AP1 FAMILY MEMBER UniProtKB/TrEMBL
Pfam DBB UniProtKB/TrEMBL
  TIR_3 UniProtKB/TrEMBL
PhenoGen Bank1 PhenoGen
PROSITE DBB UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032247 RatGTEx
SMART DBB UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A8I5ZZK5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIR4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GMB1_RAT UniProtKB/TrEMBL
  A6HVZ2 ENTREZGENE, UniProtKB/TrEMBL
  M0RAD7 ENTREZGENE, UniProtKB/TrEMBL
  Q6TUE0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Bank1  B-cell scaffold protein with ankyrin repeats 1  LOC365948  similar to AVIEF  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC365948  similar to AVIEF      Symbol and Name status set to provisional 70820 PROVISIONAL