Zc3h15l1 (zinc finger CCCH-type containing 15 like 1) - Rat Genome Database

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Gene: Zc3h15l1 (zinc finger CCCH-type containing 15 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Zc3h15l1 (Ensembl: AC115670.2)
Name: zinc finger CCCH-type containing 15 like 1
RGD ID: 1564243
Description: Predicted to enable zinc ion binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be active in cytosol. Orthologous to human ZC3H15 (zinc finger CCCH-type containing 15); INTERACTS WITH bisphenol A; cyclophosphamide; indole-3-methanol.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC291174; RGD1564243; similar to brain Zn-finger protein; zinc finger CCCH domain-containing protein 15-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,366,150 - 48,367,501 (-)NCBIGRCr8
mRatBN7.21743,670,444 - 43,671,788 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1743,670,508 - 43,671,788 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01745,745,442 - 45,746,753 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01757,731,954 - 57,733,253 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41751,330,310 - 51,331,590 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1752,812,769 - 52,814,080 (+)NCBICelera
Cytogenetic Map17q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zc3h15l1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of ZC3H15L1 mRNACTDPMID:25181051
Zc3h15l1Ratcyclophosphamide increases expressionEXP 6480464Cyclophosphamide results in increased expression of ZC3H15L1 mRNACTDPMID:27281708
Zc3h15l1Ratindole-3-methanol affects expressionEXP 6480464indole-3-carbinol affects the expression of ZC3H15L1 mRNACTDPMID:21396975


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zc3h15l1Ratcytoplasmic translation involved_inIBAPANTHER:PTN000293621 and SGD:S0000056171600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zc3h15l1Ratcytosol is_active_inIBAPANTHER:PTN000293621 and UniProtKB:Q8WU901600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zc3h15l1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Zc3h15l1Ratmetal ion binding enablesIEAInterPro:IPR000571 and InterPro:IPR0368551600115GO_REF:0000002InterProGO_REF:0000002
Zc3h15l1Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in Zc3h15l1
2 total Variants

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:61
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000005253
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 48 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat

1 to 10 of 48 rows






Ensembl Acc Id: ENSRNOT00000077475   ⟹   ENSRNOP00000071553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1743,670,508 - 43,671,788 (-)Ensembl
Rnor_6.0 Ensembl1745,745,473 - 45,746,753 (-)Ensembl
RefSeq Acc Id: XM_039096376   ⟹   XP_038952304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,366,150 - 48,367,501 (-)NCBI
mRatBN7.21743,670,444 - 43,671,788 (-)NCBI
Protein RefSeqs XP_038952304 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071553
  ENSRNOP00000071553.1
RefSeq Acc Id: XP_038952304   ⟸   XM_039096376
- UniProtKB: D4AA59 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000071553   ⟸   ENSRNOT00000077475
C3H1-type

Name Modeler Protein Id AA Range Protein Structure
AF-D4AA59-F1-model_v2 AlphaFold D4AA59 1-426 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-9167 BioCyc
Ensembl Genes ENSRNOG00000060002 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077475 ENTREZGENE
  ENSRNOT00000077475.2 UniProtKB/TrEMBL
Gene3D-CATH 6.20.400.10 UniProtKB/TrEMBL
  Zinc finger, CCCH-type UniProtKB/TrEMBL
InterPro ZC3H15/TMA46_C UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
NCBI Gene 291174 ENTREZGENE
PANTHER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 UniProtKB/TrEMBL
  ZINC FINGER-CONTAINING PROTEIN P48ZNF UniProtKB/TrEMBL
Pfam DFRP_C UniProtKB/TrEMBL
  zf-CCCH UniProtKB/TrEMBL
PhenoGen Zc3h15l1 PhenoGen
PROSITE ZF_C3H1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000060002 RatGTEx
SMART ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP SSF90229 UniProtKB/TrEMBL
UniProt D4AA59 ENTREZGENE, UniProtKB/TrEMBL
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Zc3h15l1  zinc finger CCCH-type containing 15 like 1  RGD1564243  similar to brain Zn-finger protein  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1564243  similar to brain Zn-finger protein   RGD1564243_predicted  similar to brain Zn-finger protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564243_predicted  similar to brain Zn-finger protein (predicted)  LOC291174  similar to brain Zn-finger protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC291174  similar to brain Zn-finger protein      Symbol and Name status set to provisional 70820 PROVISIONAL