Symbol:
Col4a1
Name:
collagen type IV alpha 1 chain
RGD ID:
1307148
Description:
Predicted to enable platelet-derived growth factor binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in epithelial cell differentiation. Predicted to be located in basement membrane. Predicted to be part of collagen type IV trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Biomarker of obesity and pulmonary hypertension. Human ortholog(s) of this gene implicated in brain small vessel disease 1; myocardial infarction; retinal arterial tortuosity; and uterine fibroid. Orthologous to human COL4A1 (collagen type IV alpha 1 chain); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
alpha 1 type IV collagen; collagen alpha-1(IV) chain; collagen, type IV, alpha 1; LOC290905; procollagen, type IV, alpha 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
COL4A1 (collagen type IV alpha 1 chain) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):
Col4a1 (collagen, type IV, alpha 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Col4a1 (collagen type IV alpha 1 chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
COL4A1 (collagen type IV alpha 1 chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
COL4A1 (collagen type IV alpha 1 chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Col4a1 (collagen type IV alpha 1 chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
COL4A1 (collagen type IV alpha 1 chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
COL4A1 (collagen type IV alpha 1 chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Col4a1 (collagen type IV alpha 1 chain) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
SELENOM (selenoprotein M) HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
COL4A1 (collagen type IV alpha 1 chain)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Col4a1 (collagen, type IV, alpha 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
col4a1 (collagen, type IV, alpha 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoFinder|OrthoInspector|PhylomeDB)
Drosophila melanogaster (fruit fly):
Col4a1
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoInspector|PANTHER|SonicParanoid)
Caenorhabditis elegans (roundworm):
let-2
Alliance
DIOPT (Hieranoid|InParanoid|OMA|SonicParanoid)
Drosophila melanogaster (fruit fly):
vkg
Alliance
DIOPT (OrthoFinder|OrthoInspector|PANTHER)
Caenorhabditis elegans (roundworm):
emb-9
Alliance
DIOPT (Hieranoid|OMA|OrthoFinder|PANTHER)
Xenopus tropicalis (tropical clawed frog):
col4a1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 16 84,885,597 - 84,996,482 (+) NCBI GRCr8 mRatBN7.2 16 78,183,533 - 78,294,412 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 16 78,183,533 - 78,294,412 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 16 83,463,953 - 83,574,826 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 16 86,916,625 - 87,027,510 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 16 82,157,396 - 82,268,610 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 16 83,522,162 - 83,632,153 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 83,522,162 - 83,632,153 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 16 82,987,857 - 83,097,435 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 16 83,045,183 - 83,157,835 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 16 83,031,106 - 83,143,679 (+) NCBI Celera 16 75,981,231 - 76,092,476 (+) NCBI Celera Cytogenetic Map 16 q12.5 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Col4a1 Rat (+)-schisandrin B decreases expression ISO COL4A1 (Homo sapiens) 6480464 schizandrin B results in decreased expression of COL4A1 mRNA CTD PMID:31697999 Col4a1 Rat (+)-schisandrin B multiple interactions ISO COL4A1 (Homo sapiens) 6480464 MIR30E mRNA affects the reaction [schizandrin B inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA]] more ... CTD PMID:31697999 Col4a1 Rat (-)-epigallocatechin 3-gallate decreases expression ISO COL4A1 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of COL4A1 mRNA CTD PMID:16084531 Col4a1 Rat (1->4)-beta-D-glucan multiple interactions ISO Col4a1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of COL4A1 mRNA CTD PMID:36331819 Col4a1 Rat 1,1-dichloroethene increases expression ISO Col4a1 (Mus musculus) 6480464 vinylidene chloride results in increased expression of COL4A1 mRNA CTD PMID:26682919 Col4a1 Rat 1,2-dimethylhydrazine increases expression ISO Col4a1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of COL4A1 mRNA CTD PMID:22206623 Col4a1 Rat 1,2-dimethylhydrazine multiple interactions ISO Col4a1 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of COL4A1 mRNA] CTD PMID:22206623 Col4a1 Rat 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile decreases expression EXP 6480464 Citalopram results in decreased expression of COL4A1 mRNA CTD PMID:28467792 Col4a1 Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of COL4A1 mRNA CTD PMID:25380136 Col4a1 Rat 1-naphthyl isothiocyanate multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of COL4A1 mRNA CTD PMID:27344345 Col4a1 Rat 17alpha-ethynylestradiol affects expression ISO Col4a1 (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of COL4A1 mRNA CTD PMID:17555576 Col4a1 Rat 17alpha-ethynylestradiol increases expression ISO Col4a1 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of COL4A1 mRNA CTD PMID:14976129 and PMID:17942748 Col4a1 Rat 17alpha-ethynylestradiol multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL4A1 mRNA CTD PMID:17942748 Col4a1 Rat 17beta-estradiol multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of COL4A1 mRNA CTD PMID:30165855 Col4a1 Rat 17beta-estradiol increases expression ISO Col4a1 (Mus musculus) 6480464 Estradiol results in increased expression of COL4A1 mRNA CTD PMID:39298647 Col4a1 Rat 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:23829299 Col4a1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL4A1 mRNA CTD PMID:17942748 Col4a1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of COL4A1 mRNA CTD PMID:33387578 Col4a1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of COL4A1 mRNA CTD PMID:34747641 Col4a1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Col4a1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of COL4A1 mRNA CTD PMID:21570461 Col4a1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Col4a1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of COL4A1 mRNA CTD PMID:15328365 and PMID:28922406 Col4a1 Rat 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO Col4a1 (Mus musculus) 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA] CTD PMID:18200517 Col4a1 Rat 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Col4a1 (Mus musculus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA CTD PMID:17982090 and PMID:18200517 Col4a1 Rat 2-butoxyethanol increases expression ISO Col4a1 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of COL4A1 mRNA CTD PMID:19812364 Col4a1 Rat 2-methylcholine affects expression ISO COL4A1 (Homo sapiens) 6480464 beta-methylcholine affects the expression of COL4A1 mRNA CTD PMID:21179406 Col4a1 Rat 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions EXP 6480464 Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA] more ... CTD PMID:1762292 and PMID:9175058 Col4a1 Rat 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression EXP 6480464 Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA CTD PMID:1762292 and PMID:9175058 Col4a1 Rat 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of COL4A1 protein CTD PMID:34915118 Col4a1 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of COL4A1 mRNA CTD PMID:16054899 Col4a1 Rat 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of COL4A1 mRNA CTD PMID:25380136 Col4a1 Rat 4,4'-sulfonyldiphenol increases expression ISO Col4a1 (Mus musculus) 6480464 bisphenol S results in increased expression of COL4A1 mRNA CTD PMID:30951980 and PMID:39298647 Col4a1 Rat 4,4'-sulfonyldiphenol affects methylation ISO COL4A1 (Homo sapiens) 6480464 bisphenol S affects the methylation of COL4A1 gene CTD PMID:31601247 Col4a1 Rat 6alpha-methylprednisolone multiple interactions EXP 6480464 Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL4A1 mRNA] CTD PMID:1762292 Col4a1 Rat 8'-apo-beta,psi-caroten-8'-al decreases expression ISO COL4A1 (Homo sapiens) 6480464 apocarotenal results in decreased expression of COL4A1 mRNA CTD PMID:17034753 Col4a1 Rat acetaldehyde decreases expression ISO COL4A1 (Homo sapiens) 6480464 Acetaldehyde results in decreased expression of COL4A1 mRNA and Acetaldehyde results in decreased expression of COL4A1 protein CTD PMID:8135774 Col4a1 Rat acetaldehyde multiple interactions ISO COL4A1 (Homo sapiens) 6480464 TGFB1 protein inhibits the reaction [Acetaldehyde results in decreased expression of COL4A1 protein] CTD PMID:8135774 Col4a1 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of COL4A1 mRNA CTD PMID:31881176 Col4a1 Rat acrylamide decreases expression ISO COL4A1 (Homo sapiens) 6480464 Acrylamide results in decreased expression of COL4A1 mRNA CTD PMID:32763439 Col4a1 Rat adefovir pivoxil decreases expression ISO COL4A1 (Homo sapiens) 6480464 adefovir dipivoxil results in decreased expression of COL4A1 mRNA CTD PMID:25596134 Col4a1 Rat aflatoxin B1 decreases methylation ISO COL4A1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of COL4A1 exon and Aflatoxin B1 results in decreased methylation of COL4A1 gene CTD PMID:27153756 and PMID:30157460 Col4a1 Rat aflatoxin B1 affects methylation ISO COL4A1 (Homo sapiens) 6480464 Aflatoxin B1 affects the methylation of COL4A1 intron CTD PMID:30157460 Col4a1 Rat aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of COL4A1 mRNA CTD PMID:18682491 and PMID:28700904 Col4a1 Rat aldehydo-D-glucose multiple interactions ISO COL4A1 (Homo sapiens) 6480464 MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of COL4A1 protein]] more ... CTD PMID:38124441 Col4a1 Rat aldehydo-D-glucose increases expression ISO COL4A1 (Homo sapiens) 6480464 Glucose results in increased expression of COL4A1 protein CTD PMID:38124441 Col4a1 Rat aldehydo-D-glucose multiple interactions ISO Col4a1 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]] and SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA] CTD PMID:33270355 Col4a1 Rat aldehydo-D-glucose increases expression ISO Col4a1 (Mus musculus) 6480464 Glucose results in increased expression of COL4A1 mRNA CTD PMID:33270355 Col4a1 Rat aldehydo-D-glucose multiple interactions EXP 6480464 [eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]] more ... CTD PMID:18682491 and PMID:28700904 Col4a1 Rat aldosterone multiple interactions EXP 6480464 [Eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]] more ... CTD PMID:18682491 Col4a1 Rat Alisol B multiple interactions ISO Col4a1 (Mus musculus) 6480464 alisol B inhibits the reaction [[Dietary Fats co-treated with Carbon Tetrachloride] results in increased expression of COL4A1 protein] CTD PMID:35745142 Col4a1 Rat all-trans-retinoic acid increases expression ISO Col4a1 (Mus musculus) 6480464 Tretinoin results in increased expression of COL4A1 mRNA CTD PMID:16604517 Col4a1 Rat all-trans-retinoic acid multiple interactions ISO Col4a1 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of COL4A1 mRNA CTD PMID:30951980 Col4a1 Rat all-trans-retinoic acid decreases expression ISO COL4A1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of COL4A1 mRNA CTD PMID:23724009 Col4a1 Rat all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of COL4A1 mRNA CTD PMID:17303670 Col4a1 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of COL4A1 mRNA CTD PMID:35163327 Col4a1 Rat AM-251 multiple interactions ISO COL4A1 (Homo sapiens) 6480464 AM 251 inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA] CTD PMID:27936102 Col4a1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of COL4A1 mRNA CTD PMID:16483693 Col4a1 Rat amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of COL4A1 mRNA CTD PMID:30779732 Col4a1 Rat antimycin A increases expression ISO COL4A1 (Homo sapiens) 6480464 Antimycin A results in increased expression of COL4A1 mRNA CTD PMID:33512557 Col4a1 Rat arsane affects methylation ISO COL4A1 (Homo sapiens) 6480464 Arsenic affects the methylation of COL4A1 gene CTD PMID:25304211 Col4a1 Rat arsane multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of COL4A1 mRNA CTD PMID:39836092 Col4a1 Rat arsenic atom affects methylation ISO COL4A1 (Homo sapiens) 6480464 Arsenic affects the methylation of COL4A1 gene CTD PMID:25304211 Col4a1 Rat arsenic atom multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of COL4A1 mRNA CTD PMID:39836092 Col4a1 Rat arsenite(3-) multiple interactions ISO COL4A1 (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to COL4A1 mRNA] CTD PMID:32406909 Col4a1 Rat Azoxymethane multiple interactions ISO Col4a1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL4A1 mRNA CTD PMID:29950665 Col4a1 Rat benazepril decreases expression EXP 6480464 benazepril results in decreased expression of COL4A1 mRNA CTD PMID:16191423 Col4a1 Rat benazepril multiple interactions EXP 6480464 benazepril inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA] CTD PMID:11798618 Col4a1 Rat benidipine affects expression ISO Col4a1 (Mus musculus) 6480464 benidipine affects the expression of COL4A1 mRNA CTD PMID:15721868 Col4a1 Rat benzo[a]pyrene decreases expression ISO Col4a1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of COL4A1 mRNA CTD PMID:19770486 Col4a1 Rat benzo[a]pyrene increases methylation ISO COL4A1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of COL4A1 3' UTR CTD PMID:27901495 Col4a1 Rat benzo[a]pyrene decreases methylation ISO COL4A1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of COL4A1 promoter CTD PMID:27901495 Col4a1 Rat benzo[a]pyrene increases expression ISO Col4a1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of COL4A1 mRNA CTD PMID:22610609 and PMID:32417428 Col4a1 Rat benzo[a]pyrene multiple interactions ISO Col4a1 (Mus musculus) 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of COL4A1 mRNA] CTD PMID:22228805 Col4a1 Rat benzo[b]fluoranthene increases expression ISO Col4a1 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of COL4A1 mRNA CTD PMID:26377693 Col4a1 Rat beta-carotene decreases expression ISO COL4A1 (Homo sapiens) 6480464 beta Carotene results in decreased expression of COL4A1 mRNA CTD PMID:17034753 Col4a1 Rat beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL4A1 mRNA CTD PMID:18164116 Col4a1 Rat bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of COL4A1 mRNA CTD PMID:32533902 Col4a1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Col4a1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of COL4A1 mRNA CTD PMID:33754040 Col4a1 Rat bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [Diethylhexyl Phthalate co-treated with Genistein] results in increased expression of COL4A1 mRNA CTD PMID:32533902 Col4a1 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of COL4A1 mRNA CTD PMID:25181051 Col4a1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of COL4A1 mRNA CTD PMID:38750585 Col4a1 Rat bisphenol A decreases expression ISO Col4a1 (Mus musculus) 6480464 bisphenol A results in decreased expression of COL4A1 mRNA CTD PMID:37105096 Col4a1 Rat bisphenol A increases expression ISO COL4A1 (Homo sapiens) 6480464 bisphenol A results in increased expression of COL4A1 protein CTD PMID:37567409 Col4a1 Rat bisphenol A decreases methylation ISO COL4A1 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of COL4A1 gene CTD PMID:31601247 Col4a1 Rat bisphenol A multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of COL4A1 gene CTD PMID:31601247 Col4a1 Rat bisphenol A increases expression ISO Col4a1 (Mus musculus) 6480464 bisphenol A results in increased expression of COL4A1 mRNA CTD PMID:30951980 more ... Col4a1 Rat bisphenol AF increases expression ISO COL4A1 (Homo sapiens) 6480464 bisphenol AF results in increased expression of COL4A1 protein CTD PMID:34186270 Col4a1 Rat Bisphenol B increases expression ISO COL4A1 (Homo sapiens) 6480464 bisphenol B results in increased expression of COL4A1 protein CTD PMID:34186270 Col4a1 Rat bisphenol F multiple interactions ISO Col4a1 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of COL4A1 mRNA CTD PMID:30951980 Col4a1 Rat bisphenol F increases expression ISO Col4a1 (Mus musculus) 6480464 bisphenol F results in increased expression of COL4A1 mRNA CTD PMID:30951980 Col4a1 Rat busulfan affects expression ISO Col4a1 (Mus musculus) 6480464 Busulfan affects the expression of COL4A1 mRNA CTD PMID:15941629 Col4a1 Rat cadmium atom multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of COL4A1 mRNA and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COL4A1 mRNA CTD PMID:29741670 and PMID:35301059 Col4a1 Rat cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of COL4A1 mRNA CTD PMID:25993096 Col4a1 Rat cadmium dichloride increases expression ISO COL4A1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of COL4A1 mRNA CTD PMID:38382870 Col4a1 Rat cadmium dichloride multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of COL4A1 mRNA and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of COL4A1 mRNA CTD PMID:29741670 and PMID:35301059 Col4a1 Rat cadmium dichloride decreases expression ISO COL4A1 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of COL4A1 mRNA CTD PMID:25596134 Col4a1 Rat calciol increases expression ISO Col4a1 (Mus musculus) 6480464 Cholecalciferol results in increased expression of COL4A1 mRNA CTD PMID:17170073 Col4a1 Rat cannabidiol increases expression ISO Col4a1 (Mus musculus) 6480464 Cannabidiol results in increased expression of COL4A1 mRNA CTD PMID:21542829 Col4a1 Rat cannabidiol multiple interactions ISO COL4A1 (Homo sapiens) 6480464 Cannabidiol inhibits the reaction [TNF protein results in increased expression of COL4A1 mRNA] CTD PMID:31250491 Col4a1 Rat carbamazepine affects expression ISO COL4A1 (Homo sapiens) 6480464 Carbamazepine affects the expression of COL4A1 mRNA CTD PMID:25979313 Col4a1 Rat carbon nanotube increases expression ISO COL4A1 (Homo sapiens) 6480464 Nanotubes and Carbon results in increased expression of COL4A1 mRNA CTD PMID:24389112 Col4a1 Rat carbon nanotube increases expression ISO Col4a1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Col4a1 Rat chlordecone increases expression ISO Col4a1 (Mus musculus) 6480464 Chlordecone results in increased expression of COL4A1 mRNA CTD PMID:33711761 Col4a1 Rat chloroacetaldehyde decreases expression ISO COL4A1 (Homo sapiens) 6480464 chloroacetaldehyde results in decreased expression of COL4A1 mRNA CTD PMID:25596134 Col4a1 Rat chlorpromazine decreases expression EXP 6480464 Chlorpromazine results in decreased expression of COL4A1 mRNA CTD PMID:25596134 Col4a1 Rat choline multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of COL4A1 mRNA more ... CTD PMID:20938992 more ... Col4a1 Rat cidofovir anhydrous affects expression ISO COL4A1 (Homo sapiens) 6480464 Cidofovir affects the expression of COL4A1 mRNA CTD PMID:25596134 Col4a1 Rat ciglitazone decreases expression EXP 6480464 ciglitazone results in decreased expression of COL4A1 mRNA CTD PMID:22193206 Col4a1 Rat cisplatin multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Cisplatin co-treated with RELB mutant form co-treated with TNF protein] results in increased expression of COL4A1 mRNA CTD PMID:23625948 Col4a1 Rat cisplatin multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of COL4A1 mRNA CTD PMID:27392435 Col4a1 Rat cisplatin decreases expression ISO COL4A1 (Homo sapiens) 6480464 Cisplatin results in decreased expression of COL4A1 mRNA CTD PMID:25596134 and PMID:27392435 Col4a1 Rat citalopram decreases expression EXP 6480464 Citalopram results in decreased expression of COL4A1 mRNA CTD PMID:28467792 Col4a1 Rat clofibric acid affects expression EXP 6480464 Clofibric Acid affects the expression of COL4A1 mRNA CTD PMID:17602206 Col4a1 Rat cobalt dichloride decreases expression ISO COL4A1 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of COL4A1 mRNA CTD PMID:19320972 Col4a1 Rat copper atom multiple interactions ISO Col4a1 (Mus musculus) 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of COL4A1 mRNA CTD PMID:15467011 Col4a1 Rat copper atom multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of COL4A1 mRNA and [Disulfiram binds to Copper] which results in increased expression of COL4A1 mRNA CTD PMID:24690739 and PMID:30911355 Col4a1 Rat copper(0) multiple interactions ISO Col4a1 (Mus musculus) 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of COL4A1 mRNA CTD PMID:15467011 Col4a1 Rat copper(0) multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in decreased expression of COL4A1 mRNA and [Disulfiram binds to Copper] which results in increased expression of COL4A1 mRNA CTD PMID:24690739 and PMID:30911355 Col4a1 Rat CU-O LINKAGE decreases expression ISO COL4A1 (Homo sapiens) 6480464 cupric oxide results in decreased expression of COL4A1 mRNA CTD PMID:22077320 Col4a1 Rat curcumin increases expression ISO COL4A1 (Homo sapiens) 6480464 Curcumin results in increased expression of COL4A1 mRNA CTD PMID:21594647 Col4a1 Rat curcumin multiple interactions EXP 6480464 Curcumin analog inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA] and Curcumin inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA] CTD PMID:28700904 Col4a1 Rat curcumin multiple interactions ISO Col4a1 (Mus musculus) 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA] CTD PMID:18200517 Col4a1 Rat cyclosporin A decreases expression ISO COL4A1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of COL4A1 mRNA CTD PMID:20106945 more ... Col4a1 Rat cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of COL4A1 mRNA CTD PMID:25596134 Col4a1 Rat D-glucose multiple interactions EXP 6480464 [Eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]] more ... CTD PMID:18682491 and PMID:28700904 Col4a1 Rat D-glucose increases expression ISO COL4A1 (Homo sapiens) 6480464 Glucose results in increased expression of COL4A1 protein CTD PMID:38124441 Col4a1 Rat D-glucose multiple interactions ISO COL4A1 (Homo sapiens) 6480464 MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of COL4A1 protein]] more ... CTD PMID:38124441 Col4a1 Rat D-glucose increases expression ISO Col4a1 (Mus musculus) 6480464 Glucose results in increased expression of COL4A1 mRNA CTD PMID:33270355 Col4a1 Rat D-glucose multiple interactions ISO Col4a1 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]] and SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA] CTD PMID:33270355 Col4a1 Rat D-glucose increases expression EXP 6480464 Glucose results in increased expression of COL4A1 mRNA CTD PMID:18682491 and PMID:28700904 Col4a1 Rat DDT increases expression EXP 6480464 DDT results in increased expression of COL4A1 mRNA CTD PMID:30207508 Col4a1 Rat deoxynivalenol decreases expression ISO COL4A1 (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of COL4A1 mRNA CTD PMID:31863870 Col4a1 Rat dexamethasone multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of COL4A1 mRNA CTD PMID:16054899 Col4a1 Rat dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of COL4A1 mRNA CTD PMID:35143883 Col4a1 Rat dexamethasone increases expression ISO COL4A1 (Homo sapiens) 6480464 Dexamethasone results in increased expression of COL4A1 mRNA CTD PMID:25047013 Col4a1 Rat dexamethasone increases expression ISO Col4a1 (Mus musculus) 6480464 Dexamethasone results in increased expression of COL4A1 mRNA CTD PMID:22733784 Col4a1 Rat dextran sulfate multiple interactions ISO Col4a1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL4A1 mRNA CTD PMID:29950665 Col4a1 Rat dibenz[a,h]anthracene increases expression ISO Col4a1 (Mus musculus) 6480464 1 more ... CTD PMID:26377693 Col4a1 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of COL4A1 mRNA CTD PMID:21266533 Col4a1 Rat dibutyl phthalate increases expression ISO Col4a1 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of COL4A1 mRNA CTD PMID:17361019 and PMID:21266533 Col4a1 Rat dimethyl sulfoxide increases expression EXP 6480464 Dimethyl Sulfoxide results in increased expression of COL4A1 mRNA CTD PMID:22193206 Col4a1 Rat dimethylarsinous acid decreases expression ISO COL4A1 (Homo sapiens) 6480464 dimethylarsinous acid results in decreased expression of COL4A1 mRNA CTD PMID:23487506 Col4a1 Rat dioxygen decreases expression ISO COL4A1 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of COL4A1 mRNA CTD PMID:25596134 Col4a1 Rat dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of COL4A1 protein CTD PMID:36414118 Col4a1 Rat disulfiram multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in increased expression of COL4A1 mRNA CTD PMID:24690739 Col4a1 Rat diuron increases expression EXP 6480464 Diuron results in increased expression of COL4A1 mRNA CTD PMID:21551480 Col4a1 Rat dorsomorphin multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL4A1 mRNA CTD PMID:27188386 Col4a1 Rat doxorubicin increases expression ISO Col4a1 (Mus musculus) 6480464 Doxorubicin results in increased expression of COL4A1 mRNA and Doxorubicin results in increased expression of COL4A1 protein CTD PMID:15033991 and PMID:29064158 Col4a1 Rat doxorubicin multiple interactions EXP 6480464 Doxorubicin results in increased expression of and results in increased secretion of COL4A1 protein more ... CTD PMID:19558898 Col4a1 Rat doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of COL4A1 protein CTD PMID:19558898 Col4a1 Rat doxorubicin multiple interactions ISO Col4a1 (Mus musculus) 6480464 2 more ... CTD PMID:29064158 Col4a1 Rat enalapril multiple interactions EXP 6480464 [eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]] more ... CTD PMID:18682491 and PMID:9175058 Col4a1 Rat enalapril decreases expression EXP 6480464 Enalapril results in decreased expression of COL4A1 mRNA and Enalapril results in decreased expression of COL4A1 protein CTD PMID:18682491 Col4a1 Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of COL4A1 mRNA CTD PMID:29391264 Col4a1 Rat eplerenone multiple interactions EXP 6480464 [eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]] more ... CTD PMID:18682491 Col4a1 Rat eplerenone decreases expression EXP 6480464 eplerenone results in decreased expression of COL4A1 mRNA and eplerenone results in decreased expression of COL4A1 protein CTD PMID:18682491 Col4a1 Rat escitalopram decreases expression EXP 6480464 Escitalopram results in decreased expression of COL4A1 mRNA CTD PMID:28467792 Col4a1 Rat ethanol affects expression ISO Col4a1 (Mus musculus) 6480464 Ethanol affects the expression of COL4A1 mRNA CTD PMID:30319688 Col4a1 Rat ethanol increases expression ISO Col4a1 (Mus musculus) 6480464 Ethanol results in increased expression of COL4A1 mRNA CTD PMID:30319688 Col4a1 Rat etoposide decreases expression ISO Col4a1 (Mus musculus) 6480464 Etoposide results in decreased expression of COL4A1 mRNA CTD PMID:25270620 Col4a1 Rat fenofibrate multiple interactions ISO Col4a1 (Mus musculus) 6480464 Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] CTD PMID:28871336 Col4a1 Rat fenthion increases expression ISO Col4a1 (Mus musculus) 6480464 Fenthion results in increased expression of COL4A1 mRNA CTD PMID:34813904 Col4a1 Rat fipronil increases expression EXP 6480464 fipronil results in increased expression of COL4A1 mRNA CTD PMID:34044035 Col4a1 Rat folic acid multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL4A1 mRNA more ... CTD PMID:20938992 more ... Col4a1 Rat folic acid multiple interactions ISO COL4A1 (Homo sapiens) 6480464 Folic Acid inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 mRNA] CTD PMID:29380373 Col4a1 Rat folic acid increases expression ISO Col4a1 (Mus musculus) 6480464 Folic Acid results in increased expression of COL4A1 mRNA CTD PMID:29380373 Col4a1 Rat folpet decreases expression ISO Col4a1 (Mus musculus) 6480464 folpet results in decreased expression of COL4A1 mRNA CTD PMID:31558096 Col4a1 Rat fulvestrant multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of COL4A1 gene CTD PMID:31601247 Col4a1 Rat furan increases expression EXP 6480464 furan results in increased expression of COL4A1 mRNA CTD PMID:26194646 and PMID:27387713 Col4a1 Rat genistein multiple interactions EXP 6480464 [Diethylhexyl Phthalate co-treated with Genistein] results in increased expression of COL4A1 mRNA CTD PMID:32533902 Col4a1 Rat glafenine increases expression EXP 6480464 Glafenine results in increased expression of COL4A1 mRNA CTD PMID:24136188 Col4a1 Rat glucose multiple interactions EXP 6480464 [eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]] more ... CTD PMID:18682491 and PMID:28700904 Col4a1 Rat glucose multiple interactions ISO COL4A1 (Homo sapiens) 6480464 MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of COL4A1 protein]] more ... CTD PMID:38124441 Col4a1 Rat glucose increases expression ISO COL4A1 (Homo sapiens) 6480464 Glucose results in increased expression of COL4A1 protein CTD PMID:38124441 Col4a1 Rat glucose increases expression ISO Col4a1 (Mus musculus) 6480464 Glucose results in increased expression of COL4A1 mRNA CTD PMID:33270355 Col4a1 Rat glucose multiple interactions ISO Col4a1 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]] and SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA] CTD PMID:33270355 Col4a1 Rat glucose increases expression EXP 6480464 Glucose results in increased expression of COL4A1 mRNA CTD PMID:18682491 and PMID:28700904 Col4a1 Rat glycyrrhizinic acid multiple interactions EXP 6480464 Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased expression of and results in increased secretion of COL4A1 protein] and Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased expression of COL4A1 protein] CTD PMID:19558898 Col4a1 Rat griseofulvin affects expression ISO Col4a1 (Mus musculus) 6480464 Griseofulvin affects the expression of COL4A1 mRNA CTD PMID:12735108 Col4a1 Rat hydroquinone decreases expression ISO COL4A1 (Homo sapiens) 6480464 hydroquinone results in decreased expression of COL4A1 mRNA CTD PMID:18055817 Col4a1 Rat hydroquinone increases expression ISO COL4A1 (Homo sapiens) 6480464 hydroquinone results in increased expression of COL4A1 protein CTD PMID:18055817 Col4a1 Rat hydroquinone multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein] more ... CTD PMID:18055817 Col4a1 Rat ivermectin decreases expression ISO COL4A1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of COL4A1 protein CTD PMID:32959892 Col4a1 Rat L-methionine multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Dietary Fats] results in increased expression of COL4A1 mRNA more ... CTD PMID:20938992 more ... Col4a1 Rat lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of COL4A1 mRNA CTD PMID:11578147 Col4a1 Rat lipopolysaccharide increases expression ISO Col4a1 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of COL4A1 mRNA CTD PMID:27339419 Col4a1 Rat lipopolysaccharide multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of COL4A1 mRNA CTD PMID:35811015 Col4a1 Rat losartan decreases expression EXP 6480464 Losartan results in decreased expression of COL4A1 mRNA CTD PMID:16191423 Col4a1 Rat LY294002 multiple interactions ISO Col4a1 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]] CTD PMID:33270355 Col4a1 Rat manganese atom multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of COL4A1 mRNA CTD PMID:39836092 Col4a1 Rat manganese(0) multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of COL4A1 mRNA CTD PMID:39836092 Col4a1 Rat manganese(II) chloride multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of COL4A1 mRNA CTD PMID:39836092 Col4a1 Rat mangiferin multiple interactions EXP 6480464 mangiferin inhibits the reaction [AGT protein results in increased expression of COL4A1 mRNA] CTD PMID:19706694 Col4a1 Rat metformin multiple interactions ISO Col4a1 (Mus musculus) 6480464 Metformin inhibits the reaction [Folic Acid results in increased expression of COL4A1 mRNA] CTD PMID:29380373 Col4a1 Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of COL4A1 mRNA CTD PMID:28935588 Col4a1 Rat methidathion increases expression ISO Col4a1 (Mus musculus) 6480464 methidathion results in increased expression of COL4A1 mRNA CTD PMID:34813904 Col4a1 Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of COL4A1 gene CTD PMID:35440735 Col4a1 Rat methylmercury chloride decreases expression ISO COL4A1 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of COL4A1 mRNA CTD PMID:34089799 Col4a1 Rat monocrotaline increases expression EXP 6480464 Monocrotaline results in increased expression of COL4A1 protein CTD PMID:36414118 Col4a1 Rat N-acetyl-L-cysteine decreases expression ISO COL4A1 (Homo sapiens) 6480464 Acetylcysteine results in decreased expression of COL4A1 mRNA CTD PMID:16084531 Col4a1 Rat N-ethyl-N-nitrosourea increases mutagenesis ISO Col4a1 (Mus musculus) 6480464 Ethylnitrosourea results in increased mutagenesis of COL4A1 gene CTD PMID:16724327 Col4a1 Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL4A1 mRNA CTD PMID:18164116 Col4a1 Rat N-nitrosodiethylamine increases expression ISO Col4a1 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of COL4A1 mRNA CTD PMID:24535843 Col4a1 Rat N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of COL4A1 mRNA CTD PMID:19638242 Col4a1 Rat N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of COL4A1 mRNA CTD PMID:25380136 Col4a1 Rat nickel atom increases expression ISO COL4A1 (Homo sapiens) 6480464 Nickel results in increased expression of COL4A1 mRNA CTD PMID:24768652 and PMID:25583101 Col4a1 Rat nickel sulfate decreases expression ISO COL4A1 (Homo sapiens) 6480464 nickel sulfate results in decreased expression of COL4A1 mRNA CTD PMID:22714537 Col4a1 Rat oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of COL4A1 mRNA CTD PMID:25729387 Col4a1 Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of COL4A1 mRNA CTD PMID:25729387 Col4a1 Rat ozone multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of COL4A1 mRNA CTD PMID:34911549 Col4a1 Rat paclitaxel increases expression ISO COL4A1 (Homo sapiens) 6480464 Paclitaxel results in increased expression of COL4A1 mRNA CTD PMID:19682730 Col4a1 Rat paracetamol affects expression ISO Col4a1 (Mus musculus) 6480464 Acetaminophen affects the expression of COL4A1 mRNA CTD PMID:17562736 Col4a1 Rat paracetamol increases expression ISO COL4A1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of COL4A1 mRNA CTD PMID:29067470 Col4a1 Rat paracetamol decreases expression ISO COL4A1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of COL4A1 mRNA CTD PMID:26690555 Col4a1 Rat paracetamol increases expression ISO Col4a1 (Mus musculus) 6480464 Acetaminophen results in increased expression of COL4A1 mRNA CTD PMID:11264010 and PMID:19420014 Col4a1 Rat paraquat multiple interactions ISO Col4a1 (Mus musculus) 6480464 pirfenidone inhibits the reaction [Paraquat results in increased expression of COL4A1 mRNA] and thymoquinone inhibits the reaction [Paraquat results in increased expression of COL4A1 mRNA] CTD PMID:27375216 and PMID:29273418 Col4a1 Rat paraquat increases expression ISO COL4A1 (Homo sapiens) 6480464 Paraquat results in increased expression of COL4A1 mRNA CTD PMID:34681664 Col4a1 Rat paraquat increases expression ISO Col4a1 (Mus musculus) 6480464 Paraquat results in increased expression of COL4A1 mRNA CTD PMID:21463325 more ... Col4a1 Rat PCB138 decreases expression EXP 6480464 2 more ... CTD PMID:23829299 Col4a1 Rat pentane-2,3-dione increases expression EXP 6480464 2 and 3-pentanedione results in increased expression of COL4A1 mRNA CTD PMID:25710175 Col4a1 Rat perfluorobutanesulfonic acid multiple interactions ISO Col4a1 (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with ammonium 2 more ... CTD PMID:39141488 Col4a1 Rat perfluorobutyric acid increases expression ISO Col4a1 (Mus musculus) 6480464 perfluorobutyric acid results in increased expression of COL4A1 mRNA CTD PMID:34474067 Col4a1 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Col4a1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of COL4A1 mRNA more ... CTD PMID:36331819 and PMID:39141488 Col4a1 Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of COL4A1 mRNA CTD PMID:28511854 Col4a1 Rat perfluorooctanoic acid multiple interactions ISO Col4a1 (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with ammonium 2 more ... CTD PMID:39141488 Col4a1 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of COL4A1 mRNA CTD PMID:35163327 Col4a1 Rat phenylmercury acetate increases expression ISO COL4A1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of COL4A1 mRNA CTD PMID:26272509 Col4a1 Rat phenylmercury acetate multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL4A1 mRNA CTD PMID:27188386 Col4a1 Rat pirfenidone multiple interactions ISO Col4a1 (Mus musculus) 6480464 pirfenidone inhibits the reaction [Paraquat results in increased expression of COL4A1 mRNA] CTD PMID:29273418 Col4a1 Rat pirinixic acid increases expression ISO Col4a1 (Mus musculus) 6480464 pirinixic acid results in increased expression of COL4A1 mRNA CTD PMID:18445702 more ... Col4a1 Rat potassium chromate decreases expression ISO COL4A1 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of COL4A1 mRNA CTD PMID:22714537 Col4a1 Rat progesterone decreases expression ISO COL4A1 (Homo sapiens) 6480464 Progesterone results in decreased expression of COL4A1 mRNA CTD PMID:18070364 Col4a1 Rat progesterone increases expression ISO COL4A1 (Homo sapiens) 6480464 Progesterone results in increased expression of COL4A1 mRNA CTD PMID:20864642 Col4a1 Rat rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of COL4A1 mRNA CTD PMID:28374803 Col4a1 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of COL4A1 mRNA CTD PMID:35811015 Col4a1 Rat SB 431542 multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL4A1 mRNA CTD PMID:27188386 Col4a1 Rat serpentine asbestos increases expression ISO Col4a1 (Mus musculus) 6480464 Asbestos and Serpentine results in increased expression of COL4A1 mRNA CTD PMID:21514415 Col4a1 Rat silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of COL4A1 mRNA CTD PMID:22431001 Col4a1 Rat silicon dioxide increases expression ISO Col4a1 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of COL4A1 mRNA CTD PMID:23221170 Col4a1 Rat simvastatin decreases expression ISO Col4a1 (Mus musculus) 6480464 Simvastatin results in decreased expression of COL4A1 mRNA CTD PMID:10412775 Col4a1 Rat sodium arsenite decreases expression ISO COL4A1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of COL4A1 mRNA CTD PMID:22714537 Col4a1 Rat sodium arsenite multiple interactions ISO COL4A1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of COL4A1 mRNA CTD PMID:39836092 Col4a1 Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of COL4A1 protein CTD PMID:29459688 Col4a1 Rat sodium arsenite decreases expression ISO Col4a1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of COL4A1 mRNA CTD PMID:18812580 Col4a1 Rat Soman increases expression EXP 6480464 Soman results in increased expression of COL4A1 mRNA CTD PMID:19281266 Col4a1 Rat sorafenib multiple interactions ISO COL4A1 (Homo sapiens) 6480464 sorafenib inhibits the reaction [TGFB1 protein results in increased expression of COL4A1 protein] CTD PMID:21360571 Col4a1 Rat streptozocin decreases expression ISO Col4a1 (Mus musculus) 6480464 Streptozocin results in decreased expression of COL4A1 mRNA CTD PMID:15496156 Col4a1 Rat streptozocin multiple interactions ISO Col4a1 (Mus musculus) 6480464 [fatostatin co-treated with Streptozocin] results in increased expression of COL4A1 mRNA CTD PMID:29420703 Col4a1 Rat streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of COL4A1 mRNA CTD PMID:11798618 and PMID:27997345 Col4a1 Rat streptozocin multiple interactions EXP 6480464 benazepril inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA] more ... CTD PMID:11798618 and PMID:27997345 Col4a1 Rat streptozocin increases expression ISO Col4a1 (Mus musculus) 6480464 Streptozocin results in increased expression of COL4A1 mRNA CTD PMID:17582205 Col4a1 Rat sunitinib decreases expression ISO COL4A1 (Homo sapiens) 6480464 Sunitinib results in decreased expression of COL4A1 mRNA CTD PMID:31533062 Col4a1 Rat tamoxifen affects expression ISO Col4a1 (Mus musculus) 6480464 Tamoxifen affects the expression of COL4A1 mRNA CTD PMID:17555576 Col4a1 Rat tebufenpyrad increases expression ISO COL4A1 (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of COL4A1 mRNA CTD PMID:33512557 Col4a1 Rat temozolomide increases expression ISO COL4A1 (Homo sapiens) 6480464 Temozolomide results in increased expression of COL4A1 mRNA CTD PMID:31758290 Col4a1 Rat tert-butyl hydroperoxide decreases expression ISO COL4A1 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of COL4A1 mRNA CTD PMID:15336504 Col4a1 Rat testosterone affects expression ISO Col4a1 (Mus musculus) 6480464 Testosterone affects the expression of COL4A1 mRNA CTD PMID:20403060 Col4a1 Rat tetrachloromethane increases expression ISO Col4a1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of COL4A1 mRNA CTD PMID:27339419 and PMID:31919559 Col4a1 Rat tetrachloromethane multiple interactions ISO Col4a1 (Mus musculus) 6480464 [Dietary Fats co-treated with Carbon Tetrachloride] results in increased expression of COL4A1 protein and alisol B inhibits the reaction [[Dietary Fats co-treated with Carbon Tetrachloride] results in increased expression of COL4A1 protein] CTD PMID:35745142 Col4a1 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of COL4A1 mRNA CTD PMID:10677585 and PMID:34492290 Col4a1 Rat thioacetamide multiple interactions EXP 6480464 HGF protein inhibits the reaction [Thioacetamide results in increased expression of COL4A1 mRNA] CTD PMID:10677585 Col4a1 Rat thiram increases expression ISO COL4A1 (Homo sapiens) 6480464 Thiram results in increased expression of COL4A1 mRNA CTD PMID:38568856 Col4a1 Rat thymoquinone multiple interactions ISO Col4a1 (Mus musculus) 6480464 thymoquinone inhibits the reaction [Paraquat results in increased expression of COL4A1 mRNA] CTD PMID:27375216 Col4a1 Rat titanium dioxide increases expression ISO Col4a1 (Mus musculus) 6480464 titanium dioxide results in increased expression of COL4A1 mRNA CTD PMID:27760801 Col4a1 Rat titanium dioxide multiple interactions ISO Col4a1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL4A1 mRNA CTD PMID:29950665 Col4a1 Rat toluene increases expression EXP 6480464 Toluene results in increased expression of COL4A1 mRNA CTD PMID:22967744 Col4a1 Rat topotecan increases expression EXP 6480464 Topotecan results in increased expression of COL4A1 mRNA CTD PMID:25729387 Col4a1 Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of COL4A1 mRNA CTD PMID:25729387 Col4a1 Rat trichostatin A increases expression ISO Col4a1 (Mus musculus) 6480464 trichostatin A results in increased expression of COL4A1 mRNA CTD PMID:23463510 Col4a1 Rat triclosan decreases expression ISO COL4A1 (Homo sapiens) 6480464 Triclosan results in decreased expression of COL4A1 mRNA CTD PMID:34681664 Col4a1 Rat trimellitic anhydride increases expression ISO Col4a1 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of COL4A1 mRNA CTD PMID:19042947 Col4a1 Rat triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of COL4A1 mRNA CTD PMID:30589522 Col4a1 Rat tunicamycin decreases expression ISO COL4A1 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of COL4A1 mRNA CTD PMID:22378314 Col4a1 Rat valproic acid affects expression ISO COL4A1 (Homo sapiens) 6480464 Valproic Acid affects the expression of COL4A1 mRNA CTD PMID:25979313 Col4a1 Rat valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of COL4A1 mRNA CTD PMID:29427782 Col4a1 Rat valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of COL4A1 mRNA CTD PMID:29427782 Col4a1 Rat valproic acid decreases expression ISO COL4A1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of COL4A1 mRNA CTD PMID:29154799 Col4a1 Rat vancomycin decreases expression ISO Col4a1 (Mus musculus) 6480464 Vancomycin results in decreased expression of COL4A1 mRNA CTD PMID:18930951 Col4a1 Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of COL4A1 mRNA CTD PMID:19015723 Col4a1 Rat vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of COL4A1 mRNA CTD PMID:23034163 Col4a1 Rat vitamin E increases expression ISO COL4A1 (Homo sapiens) 6480464 Vitamin E results in increased expression of COL4A1 mRNA CTD PMID:19244175 Col4a1 Rat Y-27632 multiple interactions ISO COL4A1 (Homo sapiens) 6480464 Y 27632 inhibits the reaction [ABCB4 gene mutant form results in increased expression of COL4A1 mRNA] CTD PMID:30682444 Col4a1 Rat zoledronic acid increases expression ISO Col4a1 (Mus musculus) 6480464 zoledronic acid results in increased expression of COL4A1 mRNA CTD PMID:28871336 Col4a1 Rat zoledronic acid multiple interactions ISO Col4a1 (Mus musculus) 6480464 Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] and SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] CTD PMID:28871336
Imported Annotations - KEGG (archival)
Imported Annotations - PID (archival)
(+)-schisandrin B (ISO) (-)-epigallocatechin 3-gallate (ISO) (1->4)-beta-D-glucan (ISO) 1,1-dichloroethene (ISO) 1,2-dimethylhydrazine (ISO) 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile (EXP) 1-naphthyl isothiocyanate (EXP,ISO) 17alpha-ethynylestradiol (ISO) 17beta-estradiol (ISO) 2,2',5,5'-tetrachlorobiphenyl (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4,6-trinitrobenzenesulfonic acid (ISO) 2-butoxyethanol (ISO) 2-methylcholine (ISO) 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine (EXP) 3-chloropropane-1,2-diol (EXP) 3-isobutyl-1-methyl-7H-xanthine (ISO) 4,4'-diaminodiphenylmethane (EXP) 4,4'-sulfonyldiphenol (ISO) 6alpha-methylprednisolone (EXP) 8'-apo-beta,psi-caroten-8'-al (ISO) acetaldehyde (ISO) acetamide (EXP) acrylamide (ISO) adefovir pivoxil (ISO) aflatoxin B1 (ISO) aldehydo-D-glucose (EXP,ISO) aldosterone (EXP) Alisol B (ISO) all-trans-retinoic acid (EXP,ISO) alpha-Zearalanol (EXP) AM-251 (ISO) ammonium chloride (EXP) amphetamine (EXP) antimycin A (ISO) arsane (ISO) arsenic atom (ISO) arsenite(3-) (ISO) Azoxymethane (ISO) benazepril (EXP) benidipine (ISO) benzo[a]pyrene (ISO) benzo[b]fluoranthene (ISO) beta-carotene (ISO) beta-naphthoflavone (EXP) bis(2-ethylhexyl) phthalate (EXP,ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) Bisphenol B (ISO) bisphenol F (ISO) busulfan (ISO) cadmium atom (ISO) cadmium dichloride (EXP,ISO) calciol (ISO) cannabidiol (ISO) carbamazepine (ISO) carbon nanotube (ISO) chlordecone (ISO) chloroacetaldehyde (ISO) chlorpromazine (EXP) choline (ISO) cidofovir anhydrous (ISO) ciglitazone (EXP) cisplatin (ISO) citalopram (EXP) clofibric acid (EXP) cobalt dichloride (ISO) copper atom (ISO) copper(0) (ISO) CU-O LINKAGE (ISO) curcumin (EXP,ISO) cyclosporin A (EXP,ISO) D-glucose (EXP,ISO) DDT (EXP) deoxynivalenol (ISO) dexamethasone (EXP,ISO) dextran sulfate (ISO) dibenz[a,h]anthracene (ISO) dibutyl phthalate (EXP,ISO) dimethyl sulfoxide (EXP) dimethylarsinous acid (ISO) dioxygen (EXP,ISO) disulfiram (ISO) diuron (EXP) dorsomorphin (ISO) doxorubicin (EXP,ISO) enalapril (EXP) endosulfan (EXP) eplerenone (EXP) escitalopram (EXP) ethanol (ISO) etoposide (ISO) fenofibrate (ISO) fenthion (ISO) fipronil (EXP) folic acid (ISO) folpet (ISO) fulvestrant (ISO) furan (EXP) genistein (EXP) glafenine (EXP) glucose (EXP,ISO) glycyrrhizinic acid (EXP) griseofulvin (ISO) hydroquinone (ISO) ivermectin (ISO) L-methionine (ISO) lead diacetate (EXP) lipopolysaccharide (ISO) losartan (EXP) LY294002 (ISO) manganese atom (ISO) manganese(0) (ISO) manganese(II) chloride (ISO) mangiferin (EXP) metformin (ISO) methapyrilene (EXP) methidathion (ISO) methoxychlor (EXP) methylmercury chloride (ISO) monocrotaline (EXP) N-acetyl-L-cysteine (ISO) N-ethyl-N-nitrosourea (ISO) N-nitrosodiethylamine (EXP,ISO) N-nitrosodimethylamine (EXP) nickel atom (ISO) nickel sulfate (ISO) oxaliplatin (EXP) ozone (ISO) paclitaxel (ISO) paracetamol (ISO) paraquat (ISO) PCB138 (EXP) pentane-2,3-dione (EXP) perfluorobutanesulfonic acid (ISO) perfluorobutyric acid (ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (EXP,ISO) phenylmercury acetate (ISO) pirfenidone (ISO) pirinixic acid (ISO) potassium chromate (ISO) progesterone (ISO) rotenone (EXP) S-(1,2-dichlorovinyl)-L-cysteine (ISO) SB 431542 (ISO) serpentine asbestos (ISO) silicon dioxide (EXP,ISO) simvastatin (ISO) sodium arsenite (EXP,ISO) Soman (EXP) sorafenib (ISO) streptozocin (EXP,ISO) sunitinib (ISO) tamoxifen (ISO) tebufenpyrad (ISO) temozolomide (ISO) tert-butyl hydroperoxide (ISO) testosterone (ISO) tetrachloromethane (ISO) thioacetamide (EXP) thiram (ISO) thymoquinone (ISO) titanium dioxide (ISO) toluene (EXP) topotecan (EXP) trichostatin A (ISO) triclosan (ISO) trimellitic anhydride (ISO) triphenyl phosphate (EXP) tunicamycin (ISO) valproic acid (EXP,ISO) vancomycin (ISO) vinclozolin (EXP) vitamin E (ISO) Y-27632 (ISO) zoledronic acid (ISO)
1.
Type I collagen gel modulates extracellular matrix synthesis and deposition by tracheal epithelial cells.
Davenport EA and Nettesheim P, Exp Cell Res. 1996 Feb 25;223(1):155-62.
2.
High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/faCP rats, a model of type 2 diabetic nephropathy.
Dower K, etal., PLoS One. 2017 Jul 26;12(7):e0181861. doi: 10.1371/journal.pone.0181861. eCollection 2017.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
5.
Role of COL4A1 in small-vessel disease and hemorrhagic stroke.
Gould DB, etal., N Engl J Med. 2006 Apr 6;354(14):1489-96.
6.
A possible role of thioredoxin interacting protein in the pathogenesis of streptozotocin-induced diabetic nephropathy.
Hamada Y and Fukagawa M, Kobe J Med Sci. 2007;53(1-2):53-61.
7.
Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice.
Lim AK, etal., Diabetologia. 2009 May 23.
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Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas.
Maekawa R, etal., PLoS One. 2013 Jun 20;8(6):e66632. doi: 10.1371/journal.pone.0066632. Print 2013.
9.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
10.
OMIM Disease Annotation Pipeline
OMIM Disease Annotation Pipeline
11.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
12.
PID Annotation Import Pipeline
Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13.
GOA pipeline
RGD automated data pipeline
14.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
16.
Comprehensive gene review and curation
RGD comprehensive gene curation
17.
Neonatal porencephaly and adult stroke related to mutations in collagen IV A1.
van der Knaap MS, etal., Ann Neurol. 2006 Mar;59(3):504-11.
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Effects of angiotensin II intervention on MMP-2, MMP-9, TIMP-1, and collagen expression in rats with pulmonary hypertension.
Wang XM, etal., Genet Mol Res. 2015 Mar 6;14(1):1707-17. doi: 10.4238/2015.March.6.17.
19.
Genetic risk for myocardial infarction determined by polymorphisms of candidate genes in a Japanese population.
Yamada Y, etal., J Med Genet. 2008 Apr;45(4):216-21. Epub 2007 Dec 12.
Col4a1 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 16 84,885,597 - 84,996,482 (+) NCBI GRCr8 mRatBN7.2 16 78,183,533 - 78,294,412 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 16 78,183,533 - 78,294,412 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 16 83,463,953 - 83,574,826 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 16 86,916,625 - 87,027,510 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 16 82,157,396 - 82,268,610 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 16 83,522,162 - 83,632,153 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 83,522,162 - 83,632,153 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 16 82,987,857 - 83,097,435 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 16 83,045,183 - 83,157,835 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 16 83,031,106 - 83,143,679 (+) NCBI Celera 16 75,981,231 - 76,092,476 (+) NCBI Celera Cytogenetic Map 16 q12.5 NCBI
COL4A1 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 13 110,148,963 - 110,307,157 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 13 110,148,963 - 110,307,202 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 13 110,801,310 - 110,959,504 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 13 109,599,311 - 109,757,497 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 13 109,599,311 - 109,757,459 NCBI Celera 13 91,645,588 - 91,803,669 (-) NCBI Celera Cytogenetic Map 13 q34 NCBI HuRef 13 91,400,456 - 91,558,957 (-) NCBI HuRef CHM1_1 13 110,770,028 - 110,927,927 (-) NCBI CHM1_1 T2T-CHM13v2.0 13 109,377,773 - 109,536,621 (-) NCBI T2T-CHM13v2.0
Col4a1 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 8 11,248,423 - 11,362,889 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 8 11,248,423 - 11,362,826 (-) Ensembl GRCm39 Ensembl GRCm38 8 11,198,423 - 11,312,889 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 8 11,198,423 - 11,312,826 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 8 11,198,423 - 11,312,826 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 8 11,198,403 - 11,312,702 (-) NCBI MGSCv36 mm8 Celera 8 11,372,057 - 11,487,438 (-) NCBI Celera Cytogenetic Map 8 A1.1 NCBI cM Map 8 5.53 NCBI
Col4a1 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955404 2,260,029 - 2,326,074 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955404 2,196,193 - 2,327,324 (+) NCBI ChiLan1.0 ChiLan1.0
COL4A1 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 14 111,642,358 - 111,800,305 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 13 110,324,917 - 110,482,747 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 13 91,282,617 - 91,440,187 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 13 110,407,009 - 110,562,529 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 13 110,407,009 - 110,562,529 (-) Ensembl panpan1.1 panPan2
COL4A1 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 22 58,511,210 - 58,651,949 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 22 58,512,212 - 58,588,666 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 22 58,264,155 - 58,360,735 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 22 59,132,853 - 59,274,724 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 22 59,133,398 - 59,274,709 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 22 58,634,288 - 58,774,752 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 22 58,625,802 - 58,767,327 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 22 58,660,825 - 58,801,735 (-) NCBI UU_Cfam_GSD_1.0
Col4a1 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404945 193,408,026 - 193,536,112 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936472 2,416,566 - 2,542,814 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936472 2,416,043 - 2,543,561 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
COL4A1 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 11 76,858,356 - 76,997,322 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 11 76,858,332 - 76,997,409 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 11 84,372,388 - 84,460,293 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
COL4A1 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 3 88,410,800 - 88,564,191 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 3 88,412,168 - 88,564,057 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666046 45,126,545 - 45,280,009 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Col4a1
.
Predicted Target Of
Count of predictions: 127 Count of miRNA genes: 112 Interacting mature miRNAs: 118 Transcripts: ENSRNOT00000057386 Prediction methods: Miranda Result types: miRGate_prediction
2300163 Bmd64 Bone mineral density QTL 64 5.3 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 16 37752156 82752156 Rat 7411648 Foco22 Food consumption QTL 22 15 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 16 52726464 84729064 Rat 1600378 Arunc4 Aerobic running capacity QTL 4 0.03 exercise endurance trait (VT:0002332) maximum distance run on treadmill (CMO:0001406) 16 380245 80345693 Rat 1578768 Stresp22 Stress response QTL 22 2.8 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 16 35288870 80288870 Rat 2293690 Bss45 Bone structure and strength QTL 45 5.13 0.0001 lumbar vertebra morphology trait (VT:0010494) lumbar vertebra cortical cross-sectional area (CMO:0001690) 16 37752156 82752156 Rat 8694364 Abfw7 Abdominal fat weight QTL 7 12.22 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 16 52726464 84729064 Rat 8694429 Bw164 Body weight QTL 164 5 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 16 52726464 84729064 Rat 7205510 Activ5 Activity QTL 5 3.78 0.00028 locomotor behavior trait (VT:0001392) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 16 42396345 84729064 Rat 70205 Gcr3 Gastric cancer resistance QTL 3 2.3 stomach morphology trait (VT:0000470) stomach tumor diameter (CMO:0001889) 16 17696791 82635055 Rat 631525 Pia14 Pristane induced arthritis QTL 14 4.4 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 16 55711087 83402471 Rat
D13S1449
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 16 84,995,185 - 84,995,287 (+) Marker Load Pipeline mRatBN7.2 16 78,293,115 - 78,293,216 (+) MAPPER mRatBN7.2 Rnor_6.0 16 83,630,857 - 83,630,957 NCBI Rnor6.0 Rnor_5.0 16 83,096,139 - 83,096,239 UniSTS Rnor5.0 RGSC_v3.4 16 83,156,539 - 83,156,639 UniSTS RGSC3.4 Celera 16 76,091,180 - 76,091,280 UniSTS Cytogenetic Map 16 q12.5 UniSTS
D16Nds29
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 16 78,293,623 - 78,293,735 (+) MAPPER mRatBN7.2 Rnor_6.0 16 83,631,365 - 83,631,476 NCBI Rnor6.0 Rnor_5.0 16 83,096,647 - 83,096,758 UniSTS Rnor5.0 RGSC_v3.4 16 83,157,047 - 83,157,158 UniSTS RGSC3.4 Celera 16 76,091,688 - 76,091,799 UniSTS Cytogenetic Map 16 q12.5 UniSTS
RH128563
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 16 78,293,891 - 78,294,076 (+) MAPPER mRatBN7.2 Rnor_6.0 16 83,631,633 - 83,631,817 NCBI Rnor6.0 Rnor_5.0 16 83,096,915 - 83,097,099 UniSTS Rnor5.0 RGSC_v3.4 16 83,157,315 - 83,157,499 UniSTS RGSC3.4 Celera 16 76,091,956 - 76,092,140 UniSTS Cytogenetic Map 16 q12.5 UniSTS
RH129454
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 16 78,293,113 - 78,293,293 (+) MAPPER mRatBN7.2 Rnor_6.0 16 83,630,855 - 83,631,034 NCBI Rnor6.0 Rnor_5.0 16 83,096,137 - 83,096,316 UniSTS Rnor5.0 RGSC_v3.4 16 83,156,537 - 83,156,716 UniSTS RGSC3.4 Celera 16 76,091,178 - 76,091,357 UniSTS RH 3.4 Map 16 760.3 UniSTS Cytogenetic Map 16 q12.5 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
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Ensembl Acc Id:
ENSRNOT00000057386 ⟹ ENSRNOP00000054197
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 16 78,183,533 - 78,294,412 (+) Ensembl Rnor_6.0 Ensembl 16 83,522,162 - 83,632,153 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000114480 ⟹ ENSRNOP00000091137
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 16 78,183,533 - 78,293,330 (+) Ensembl
RefSeq Acc Id:
NM_001135009 ⟹ NP_001128481
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 16 84,885,597 - 84,996,482 (+) NCBI mRatBN7.2 16 78,183,533 - 78,294,412 (+) NCBI Rnor_6.0 16 83,522,162 - 83,632,153 (+) NCBI Rnor_5.0 16 82,987,857 - 83,097,435 (+) NCBI RGSC_v3.4 16 83,045,183 - 83,157,835 (+) RGD Celera 16 75,981,231 - 76,092,476 (+) RGD
Sequence:
GAGGGGAGGGGGCAGCGCCAACAAATTGGGGAGCTCCTCGGGCGGCGCGCTCAGGTCTCTGCTCAGAGCCACCGCACCCGGGACGGTGAGCAGGGCTCACGCCCGGGCCCTCCGAGACTGAGCACCTC
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RefSeq Acc Id:
NP_001128481 ⟸ NM_001135009
- Peptide Label:
precursor
- UniProtKB:
F1MA59 (UniProtKB/TrEMBL)
- Sequence:
MGPRLSVWLLLPLAALLLHEERSRAAAKGDCGGSGCGKCDCHGVKGQKGERGFPGLQGVIGFPGMQGPEGPHGPPGQKGDAGEPGLPGTKGTRGPPGAAGYPGNPGLPGIPGQDGPPGPPGIPGCNGT
hide sequence
Ensembl Acc Id:
ENSRNOP00000054197 ⟸ ENSRNOT00000057386
Ensembl Acc Id:
ENSRNOP00000091137 ⟸ ENSRNOT00000114480
RGD ID: 13700247 Promoter ID: EPDNEW_R10770 Type: multiple initiation site Name: Col4a1_1 Description: collagen type IV alpha 1 chain SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 16 83,522,214 - 83,522,274 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-06-01
Col4a1
collagen type IV alpha 1 chain
Col4a1
collagen, type IV, alpha 1
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2008-04-25
Col4a1
collagen, type IV, alpha 1
Col4a1
procollagen, type IV, alpha 1
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2005-12-06
Col4a1
procollagen, type IV, alpha 1
Col4a1_predicted
procollagen, type IV, alpha 1 (predicted)
Symbol and Name updated
1559027 APPROVED
2005-01-12
Col4a1_predicted
procollagen, type IV, alpha 1 (predicted)
Symbol and Name status set to approved
70820 APPROVED
