Fgd5 (FYVE, RhoGEF and PH domain containing 5) - Rat Genome Database

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Gene: Fgd5 (FYVE, RhoGEF and PH domain containing 5) Rattus norvegicus
Analyze
Symbol: Fgd5
Name: FYVE, RhoGEF and PH domain containing 5
RGD ID: 1305589
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Orthologous to human FGD5 (FYVE, RhoGEF and PH domain containing 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cocaine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FYVE, RhoGEF and PH domain-containing protein 5; LOC362402
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84126,054,201 - 126,151,698 (+)NCBIGRCr8
mRatBN7.24124,497,061 - 124,594,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4124,497,068 - 124,594,563 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4129,964,067 - 130,061,661 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04125,738,497 - 125,836,093 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04124,363,028 - 124,460,626 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04123,865,557 - 123,962,904 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4123,865,725 - 123,962,881 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04189,298,419 - 189,395,965 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,237,049 - 126,276,419 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14126,432,006 - 126,521,133 (+)NCBI
Celera4113,414,985 - 113,512,420 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgd5Rat3p deletion syndrome  ISOFGD5 (Homo sapiens)8554872ClinVar Annotator: match by term: 3p- syndromeClinVarPMID:31690835
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgd5RatBreast Neoplasms  ISOFGD5 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25151356
Fgd5RatDisease Progression  ISOFGD5 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:34427968
Fgd5RatStomach Neoplasms  ISOFGD5 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:34427968

1 to 20 of 73 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgd5Rat1,1-dichloroethene decreases expressionISOFgd5 (Mus musculus)6480464vinylidene chloride results in decreased expression of FGD5 mRNACTDPMID:26682919
Fgd5Rat1,2-dimethylhydrazine increases expressionISOFgd5 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of FGD5 mRNACTDPMID:22206623
Fgd5Rat17beta-estradiol multiple interactionsISOFGD5 (Homo sapiens)6480464[Estradiol binds to ESR2 protein] which results in increased expression of FGD5 mRNACTDPMID:20404318
Fgd5Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOFgd5 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of FGD5 mRNACTDPMID:21570461
Fgd5Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of FGD5 mRNACTDPMID:34747641
Fgd5Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of FGD5 mRNACTDPMID:32109520
Fgd5Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOFgd5 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of FGD5 mRNACTDPMID:23994337
Fgd5Rat3,3',4,4',5-pentachlorobiphenyl increases expressionISOFgd5 (Mus musculus)64804643 more ...CTDPMID:23994337
Fgd5Rat3,4-methylenedioxymethamphetamine increases expressionISOFgd5 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of FGD5 mRNACTDPMID:26251327
Fgd5Rat4,4'-diaminodiphenylmethane increases expressionISOFgd5 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of FGD5 mRNACTDPMID:18648102
Fgd5Rat4,4'-sulfonyldiphenol increases expressionISOFgd5 (Mus musculus)6480464bisphenol S results in increased expression of FGD5 mRNACTDPMID:30951980 and PMID:33297965
Fgd5Rat4,4'-sulfonyldiphenol decreases methylationISOFGD5 (Homo sapiens)6480464bisphenol S results in decreased methylation of FGD5 geneCTDPMID:31601247
Fgd5Rat4,4'-sulfonyldiphenol decreases methylationISOFgd5 (Mus musculus)6480464bisphenol S results in decreased methylation of FGD5 exonCTDPMID:33297965
Fgd5Rat4-hydroxyphenyl retinamide increases expressionISOFgd5 (Mus musculus)6480464Fenretinide results in increased expression of FGD5 mRNACTDPMID:28973697
Fgd5Rat5-aza-2'-deoxycytidine affects expressionISOFGD5 (Homo sapiens)6480464Decitabine affects the expression of FGD5 mRNACTDPMID:23300844
Fgd5Rataflatoxin B1 decreases methylationISOFGD5 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of FGD5 exonCTDPMID:30157460
Fgd5Rataflatoxin B1 decreases expressionISOFGD5 (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of FGD5 mRNACTDPMID:32234424
Fgd5RatAflatoxin B2 alpha increases methylationISOFGD5 (Homo sapiens)6480464aflatoxin B2 results in increased methylation of FGD5 exonCTDPMID:30157460
Fgd5Ratamiodarone increases expressionISOFGD5 (Homo sapiens)6480464Amiodarone results in increased expression of FGD5 mRNACTDPMID:19774075
Fgd5Ratbenzo[a]pyrene increases mutagenesisISOFGD5 (Homo sapiens)6480464Benzo(a)pyrene results in increased mutagenesis of FGD5 geneCTDPMID:25435355

1 to 20 of 73 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgd5Ratcytoplasm is_active_inIBAFB:FBgn0035761 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fgd5Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Fgd5Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Fgd5Ratcytoskeleton located_inIEAUniProtKB-SubCell:SL-00901600115GO_REF:0000044UniProtGO_REF:0000044
Fgd5Ratplasma membrane located_inIEAUniProtKB:A0A2X0SFF2 and ensembl:ENSP000002850461600115GO_REF:0000107EnsemblGO_REF:0000107
Fgd5Ratplasma membrane located_inISOFGD5 (Homo sapiens) and UniProtKB:Q6ZNL6-11624291 RGDGO_REF:0000052
Fgd5Ratplasma membrane located_inIEAUniProtKB:Q6ZNL6 and ensembl:ENSP000002850461600115GO_REF:0000107EnsemblGO_REF:0000107

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Fgd5Ratguanyl-nucleotide exchange factor activity enablesIBAFB:FBgn0035761 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fgd5Ratguanyl-nucleotide exchange factor activity enablesIEAInterPro:IPR0002191600115GO_REF:0000002InterProGO_REF:0000002
Fgd5Ratguanyl-nucleotide exchange factor activity enablesIEAUniProtKB-KW:KW-03441600115GO_REF:0000043UniProtGO_REF:0000043
Fgd5Ratmetal ion binding enablesIEAInterPro:IPR0003061600115GO_REF:0000002InterProGO_REF:0000002
Fgd5Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Fgd5Ratprotein binding enablesISOFGD5 (Homo sapiens)1624291UniProtKB:O43463 more ...RGDPMID:23455924 and PMID:32814053
Fgd5Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8889548  



Fgd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84126,054,201 - 126,151,698 (+)NCBIGRCr8
mRatBN7.24124,497,061 - 124,594,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4124,497,068 - 124,594,563 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4129,964,067 - 130,061,661 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04125,738,497 - 125,836,093 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04124,363,028 - 124,460,626 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04123,865,557 - 123,962,904 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4123,865,725 - 123,962,881 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04189,298,419 - 189,395,965 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,237,049 - 126,276,419 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14126,432,006 - 126,521,133 (+)NCBI
Celera4113,414,985 - 113,512,420 (+)NCBICelera
Cytogenetic Map4q34NCBI
FGD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38314,810,688 - 14,934,571 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl314,810,853 - 14,934,571 (+)EnsemblGRCh38hg38GRCh38
GRCh37314,860,469 - 14,976,078 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36314,835,810 - 14,950,899 (+)NCBINCBI36Build 36hg18NCBI36
Build 34314,835,809 - 14,950,899NCBI
Celera314,798,707 - 14,914,334 (+)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef314,796,239 - 14,911,901 (+)NCBIHuRef
CHM1_1314,811,508 - 14,927,026 (+)NCBICHM1_1
T2T-CHM13v2.0314,813,154 - 14,937,021 (+)NCBIT2T-CHM13v2.0
Fgd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39691,955,809 - 92,052,986 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl691,955,859 - 92,052,985 (+)EnsemblGRCm39 Ensembl
GRCm38691,978,827 - 92,076,005 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl691,978,878 - 92,076,004 (+)EnsemblGRCm38mm10GRCm38
MGSCv37691,937,104 - 92,025,999 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36691,952,614 - 92,041,509 (+)NCBIMGSCv36mm8
Celera693,881,166 - 93,970,222 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map641.0NCBI
Fgd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542917,304,992 - 17,366,051 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542917,297,123 - 17,367,365 (+)NCBIChiLan1.0ChiLan1.0
FGD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,792,284 - 14,915,818 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1314,797,051 - 14,920,581 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0314,732,712 - 14,856,251 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1315,072,214 - 15,195,608 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl315,072,214 - 15,195,608 (+)Ensemblpanpan1.1panPan2
FGD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1204,905,898 - 5,028,637 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl204,906,800 - 5,027,537 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha204,937,689 - 5,065,901 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0204,921,741 - 5,050,020 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl204,928,132 - 5,050,017 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1204,640,172 - 4,768,367 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0204,991,109 - 5,119,078 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0204,974,498 - 5,102,732 (+)NCBIUU_Cfam_GSD_1.0
Fgd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494218,425,918 - 18,477,549 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936602436,058 - 482,370 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936602432,114 - 483,964 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1369,594,223 - 69,724,056 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11369,594,225 - 69,724,051 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21377,089,973 - 77,129,974 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12250,746,210 - 50,868,659 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2250,746,303 - 50,870,049 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041115,624,838 - 115,748,381 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248721,034,782 - 1,103,655 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248721,037,607 - 1,103,617 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Fgd5
475 total Variants

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:67
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000051022, ENSRNOT00000072925
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4116179486151161268Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat

1 to 10 of 51 rows
RH127786  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24124,594,140 - 124,594,360 (+)MAPPERmRatBN7.2
Rnor_6.04123,962,481 - 123,962,700NCBIRnor6.0
Rnor_5.04189,298,627 - 189,298,846UniSTSRnor5.0
RGSC_v3.44126,275,983 - 126,276,202UniSTSRGSC3.4
Celera4113,511,997 - 113,512,216UniSTS
RH 3.4 Map4736.04UniSTS
Cytogenetic Map4q34UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000051022   ⟹   ENSRNOP00000040013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4124,497,068 - 124,594,563 (+)Ensembl
Rnor_6.0 Ensembl4123,865,725 - 123,962,881 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094992   ⟹   ENSRNOP00000079142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4124,505,240 - 124,592,840 (+)Ensembl
RefSeq Acc Id: NM_001108637   ⟹   NP_001102107
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84126,054,210 - 126,151,698 (+)NCBI
mRatBN7.24124,497,068 - 124,594,564 (+)NCBI
RefSeq Acc Id: XM_006236926   ⟹   XP_006236988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84126,054,201 - 126,151,683 (+)NCBI
mRatBN7.24124,497,061 - 124,594,564 (+)NCBI
Rnor_6.04123,865,557 - 123,962,904 (+)NCBI
Rnor_5.04189,298,419 - 189,395,965 (-)NCBI
Sequence:
Protein RefSeqs NP_001102107 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236988 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91384 (Get FASTA)   NCBI Sequence Viewer  
  EDL91385 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040013
  ENSRNOP00000040013.5
  ENSRNOP00000079142.1
  ENSRNOP00000101814
RefSeq Acc Id: XP_006236988   ⟸   XM_006236926
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZMC4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000040013   ⟸   ENSRNOT00000051022
RefSeq Acc Id: NP_001102107   ⟸   NM_001108637
- UniProtKB: F1LTE6 (UniProtKB/TrEMBL),   A0A8I5ZMC4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079142   ⟸   ENSRNOT00000094992
DH   FYVE-type   PH

Name Modeler Protein Id AA Range Protein Structure
AF-F1LTE6-F1-model_v2 AlphaFold F1LTE6 1-1519 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693269
Promoter ID:EPDNEW_R3782
Type:initiation region
Name:Fgd5_1
Description:FYVE, RhoGEF and PH domain containing 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04123,865,629 - 123,865,689EPDNEW


1 to 35 of 35 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-43703 BioCyc
Ensembl Genes ENSRNOG00000010213 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000051022 ENTREZGENE
  ENSRNOT00000051022.7 UniProtKB/TrEMBL
  ENSRNOT00000094992.1 UniProtKB/TrEMBL
  ENSRNOT00000153524 ENTREZGENE
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  FYVE_RhoGEF_PH UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene 362402 ENTREZGENE
PANTHER FACIOGENITAL DYSPLASIA PROTEIN UniProtKB/TrEMBL
  FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 5 UniProtKB/TrEMBL
Pfam FYVE UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PhenoGen Fgd5 PhenoGen
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010213 RatGTEx
SMART FYVE UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A0A8I5ZMC4 ENTREZGENE, UniProtKB/TrEMBL
  F1LTE6 ENTREZGENE, UniProtKB/TrEMBL
1 to 35 of 35 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Fgd5  FYVE, RhoGEF and PH domain containing 5   Fgd5_predicted  FYVE, RhoGEF and PH domain containing 5 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fgd5_predicted  FYVE, RhoGEF and PH domain containing 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED