Runx1t1 (RUNX1 partner transcriptional co-repressor 1) - Rat Genome Database

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Gene: Runx1t1 (RUNX1 partner transcriptional co-repressor 1) Rattus norvegicus
Analyze
Symbol: Runx1t1
Name: RUNX1 partner transcriptional co-repressor 1
RGD ID: 1305490
Description: Predicted to enable DNA-binding transcription factor binding activity; identical protein binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and negative regulation of fat cell differentiation. Predicted to act upstream of or within fat cell differentiation and regulation of DNA-templated transcription. Predicted to be located in nuclear matrix and nucleoplasm. Predicted to be active in nucleus. Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1); PARTICIPATES IN acute myeloid leukemia pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acute myelogenous leukemia 1 translocation 1 protein; Cbfa2t1; CBFA2T1 identified gene homolog; CBFA2T1 identified gene homolog (human); core-binding factor, runt domain, alpha subunit 2; core-binding factor, runt domain, alpha subunit 2, translocated to, 1; cyclin D-related; LOC362489; runt-related transcription factor 1; runt-related transcription factor 1; translocated to, 1 (cyclin D-related); RUNX1 translocation partner 1; translocated to, 1; translocated to, 1 (cyclin D-related)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8531,984,946 - 32,136,878 (+)NCBIGRCr8
mRatBN7.2527,187,674 - 27,338,070 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl527,187,551 - 27,335,592 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx529,354,513 - 29,460,385 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0530,947,153 - 31,053,031 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0530,907,305 - 31,013,180 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0527,284,921 - 27,440,802 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl527,312,928 - 27,442,841 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0531,976,957 - 32,132,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4528,230,322 - 28,338,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1528,188,640 - 28,338,441 (+)NCBI
Celera526,502,150 - 26,607,942 (+)NCBICelera
Cytogenetic Map5q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-naphthylamine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
Aroclor 1254  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
chloroprene  (EXP)
choline  (ISO)
cocaine  (EXP)
crotonaldehyde  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diethyl malate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
glyphosate  (EXP)
GW 4064  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
nitrofen  (EXP)
panobinostat  (ISO)
paracetamol  (EXP)
PCB138  (EXP)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
tanespimycin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
wogonin  (ISO)
XL147  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear matrix  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mutational analysis of RUNX1T1 gene in acute leukemias, breast and lung carcinomas. Kim YR, etal., Leuk Res. 2011 Sep;35(9):e157-8. doi: 10.1016/j.leukres.2011.04.024. Epub 2011 May 14.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10973986   PMID:15509789   PMID:23251453   PMID:25473084   PMID:26774823  


Genomics

Comparative Map Data
Runx1t1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8531,984,946 - 32,136,878 (+)NCBIGRCr8
mRatBN7.2527,187,674 - 27,338,070 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl527,187,551 - 27,335,592 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx529,354,513 - 29,460,385 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0530,947,153 - 31,053,031 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0530,907,305 - 31,013,180 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0527,284,921 - 27,440,802 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl527,312,928 - 27,442,841 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0531,976,957 - 32,132,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4528,230,322 - 28,338,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1528,188,640 - 28,338,441 (+)NCBI
Celera526,502,150 - 26,607,942 (+)NCBICelera
Cytogenetic Map5q13NCBI
RUNX1T1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38891,954,967 - 92,103,385 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl891,954,972 - 92,103,385 (-)EnsemblGRCh38hg38GRCh38
GRCh37892,967,195 - 93,115,613 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36893,040,328 - 93,176,619 (-)NCBINCBI36Build 36hg18NCBI36
Build 34893,040,327 - 93,144,367NCBI
Celera889,157,513 - 89,293,797 (-)NCBICelera
Cytogenetic Map8q21.3NCBI
HuRef888,174,218 - 88,322,535 (-)NCBIHuRef
CHM1_1893,007,519 - 93,155,728 (-)NCBICHM1_1
T2T-CHM13v2.0893,080,060 - 93,228,496 (-)NCBIT2T-CHM13v2.0
Runx1t1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39413,742,628 - 13,895,056 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl413,743,436 - 13,893,649 (+)EnsemblGRCm39 Ensembl
GRCm38413,742,628 - 13,895,056 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl413,743,436 - 13,893,649 (+)EnsemblGRCm38mm10GRCm38
MGSCv37413,670,449 - 13,820,796 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36413,711,929 - 13,818,264 (+)NCBIMGSCv36mm8
Celera413,520,441 - 13,687,612 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map45.88NCBI
Runx1t1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554178,580,363 - 8,721,416 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554178,580,355 - 8,714,267 (-)NCBIChiLan1.0ChiLan1.0
RUNX1T1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27109,297,517 - 109,443,961 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1884,836,338 - 84,982,863 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0888,588,560 - 88,736,614 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1890,538,965 - 90,686,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl890,538,965 - 90,686,689 (-)Ensemblpanpan1.1panPan2
RUNX1T1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12937,156,861 - 37,289,934 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2937,158,659 - 37,297,879 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2937,305,761 - 37,440,000 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02937,355,710 - 37,490,023 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2937,357,901 - 37,498,074 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12937,374,916 - 37,509,114 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02937,356,296 - 37,490,752 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02937,796,907 - 37,931,529 (-)NCBIUU_Cfam_GSD_1.0
Runx1t1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530342,278,379 - 42,410,876 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365445,383,350 - 5,522,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365445,381,829 - 5,514,364 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUNX1T1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl444,599,760 - 44,743,418 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1444,600,292 - 44,745,954 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2448,029,947 - 48,172,694 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RUNX1T1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1886,984,638 - 87,127,648 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl886,988,366 - 87,090,875 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603953,720,972 - 53,868,048 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Runx1t1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624744783 - 63,720 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Runx1t1
972 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:203
Count of miRNA genes:122
Interacting mature miRNAs:172
Transcripts:ENSRNOT00000066191
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5213896532656739Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
61462Niddm10Non-insulin dependent diabetes mellitus QTL 103.90.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)5511215947171491Rat
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)52483871044045280Rat

Markers in Region
D5Uwm12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,268,736 - 27,268,904 (+)MAPPERmRatBN7.2
Rnor_6.0527,373,084 - 27,373,251NCBIRnor6.0
Rnor_5.0532,064,554 - 32,064,721UniSTSRnor5.0
RGSC_v3.4528,271,397 - 28,271,565RGDRGSC3.4
RGSC_v3.4528,271,398 - 28,271,565UniSTSRGSC3.4
RGSC_v3.1528,271,397 - 28,271,565RGD
Celera526,541,197 - 26,541,364UniSTS
Cytogenetic Map5q13UniSTS
D8S1950  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,334,597 - 27,334,703 (+)MAPPERmRatBN7.2
Rnor_6.0527,439,025 - 27,439,130NCBIRnor6.0
Rnor_5.0532,130,177 - 32,130,282UniSTSRnor5.0
RGSC_v3.4528,337,448 - 28,337,553UniSTSRGSC3.4
Celera526,606,949 - 26,607,054UniSTS
Cytogenetic Map5q13UniSTS
RH80460  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,337,843 - 27,338,081 (+)MAPPERmRatBN7.2
Rnor_6.0527,442,270 - 27,442,507NCBIRnor6.0
Rnor_5.0532,133,422 - 32,133,659UniSTSRnor5.0
RGSC_v3.4528,340,693 - 28,340,930UniSTSRGSC3.4
Celera526,610,194 - 26,610,431UniSTS
Cytogenetic Map5q13UniSTS
RH144682  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,291,586 - 27,291,788 (+)MAPPERmRatBN7.2
Rnor_6.0527,396,031 - 27,396,232NCBIRnor6.0
Rnor_5.0532,087,501 - 32,087,702UniSTSRnor5.0
RGSC_v3.4528,294,243 - 28,294,444UniSTSRGSC3.4
Celera526,564,083 - 26,564,284UniSTS
RH 3.4 Map5154.7UniSTS
Cytogenetic Map5q13UniSTS
BE118933  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,245,002 - 27,245,152 (+)MAPPERmRatBN7.2
Rnor_6.0527,342,290 - 27,342,439NCBIRnor6.0
Rnor_5.0532,034,172 - 32,034,321UniSTSRnor5.0
RGSC_v3.4528,247,382 - 28,247,531UniSTSRGSC3.4
Celera526,517,522 - 26,517,671UniSTS
RH 3.4 Map5153.6UniSTS
Cytogenetic Map5q13UniSTS
BE107258  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,265,438 - 27,265,620 (+)MAPPERmRatBN7.2
Rnor_6.0527,369,786 - 27,369,967NCBIRnor6.0
Rnor_5.0532,061,256 - 32,061,437UniSTSRnor5.0
RGSC_v3.4528,268,100 - 28,268,281UniSTSRGSC3.4
Celera526,537,899 - 26,538,080UniSTS
RH 3.4 Map5153.6UniSTS
Cytogenetic Map5q13UniSTS
Cbfa2t1h  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,334,989 - 27,335,185 (+)MAPPERmRatBN7.2
Rnor_6.0527,439,416 - 27,439,611NCBIRnor6.0
Rnor_5.0532,130,568 - 32,130,763UniSTSRnor5.0
RGSC_v3.4528,337,839 - 28,338,034UniSTSRGSC3.4
Celera526,607,340 - 26,607,535UniSTS
Cytogenetic Map5q13UniSTS
Runx1t1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,335,192 - 27,335,244 (+)MAPPERmRatBN7.2
Rnor_6.0527,439,619 - 27,439,670NCBIRnor6.0
Rnor_5.0532,130,771 - 32,130,822UniSTSRnor5.0
RGSC_v3.4528,338,042 - 28,338,093UniSTSRGSC3.4
Celera526,607,543 - 26,607,594UniSTS
Cytogenetic Map5q13UniSTS
UniSTS:225014  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,334,362 - 27,334,513 (+)MAPPERmRatBN7.2
Rnor_6.0527,438,790 - 27,438,940NCBIRnor6.0
Rnor_5.0532,129,942 - 32,130,092UniSTSRnor5.0
RGSC_v3.4528,337,213 - 28,337,363UniSTSRGSC3.4
Celera526,606,714 - 26,606,864UniSTS
Cytogenetic Map5q13UniSTS
Runx1t1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,334,082 - 27,334,504 (+)MAPPERmRatBN7.2
Rnor_6.0527,438,510 - 27,438,931NCBIRnor6.0
Rnor_5.0532,129,662 - 32,130,083UniSTSRnor5.0
RGSC_v3.4528,336,933 - 28,337,354UniSTSRGSC3.4
Celera526,606,434 - 26,606,855UniSTS
Cytogenetic Map5q13UniSTS
UniSTS:546979  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2527,334,193 - 27,335,253 (+)MAPPERmRatBN7.2
Rnor_6.0527,438,621 - 27,439,679NCBIRnor6.0
Rnor_5.0532,129,773 - 32,130,831UniSTSRnor5.0
Celera526,606,545 - 26,607,603UniSTS
Cytogenetic Map5q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 12 4 4 4 64 4 24 3
Low 3 31 30 14 18 14 8 10 10 30 17 8 8
Below cutoff 23 23 1 23 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000066191   ⟹   ENSRNOP00000063830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl527,229,712 - 27,335,592 (+)Ensembl
Rnor_6.0 Ensembl527,326,762 - 27,440,018 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078102   ⟹   ENSRNOP00000071431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl527,195,628 - 27,335,592 (+)Ensembl
Rnor_6.0 Ensembl527,312,928 - 27,442,841 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094571   ⟹   ENSRNOP00000090913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl527,195,367 - 27,335,592 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111262   ⟹   ENSRNOP00000081192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl527,187,551 - 27,335,592 (+)Ensembl
RefSeq Acc Id: NM_001108657   ⟹   NP_001102127
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8532,026,989 - 32,132,855 (+)NCBI
mRatBN7.2527,229,712 - 27,335,592 (+)NCBI
Rnor_6.0527,326,762 - 27,440,018 (+)NCBI
Rnor_5.0531,976,957 - 32,132,101 (+)NCBI
RGSC_v3.4528,230,322 - 28,338,441 (+)RGD
Celera526,502,150 - 26,607,942 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237901   ⟹   XP_006237963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8531,984,946 - 32,136,878 (+)NCBI
mRatBN7.2527,187,674 - 27,337,349 (+)NCBI
Rnor_6.0527,284,921 - 27,440,802 (+)NCBI
Rnor_5.0531,976,957 - 32,132,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237903   ⟹   XP_006237965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8531,992,143 - 32,136,878 (+)NCBI
mRatBN7.2527,194,854 - 27,338,070 (+)NCBI
Rnor_6.0527,286,383 - 27,440,802 (+)NCBI
Rnor_5.0531,976,957 - 32,132,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237904   ⟹   XP_006237966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8531,984,946 - 32,136,878 (+)NCBI
mRatBN7.2527,187,684 - 27,337,349 (+)NCBI
Rnor_6.0527,284,921 - 27,440,802 (+)NCBI
Rnor_5.0531,976,957 - 32,132,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763548   ⟹   XP_008761770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8531,992,866 - 32,136,878 (+)NCBI
mRatBN7.2527,195,580 - 27,338,070 (+)NCBI
Rnor_6.0527,292,976 - 27,440,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763550   ⟹   XP_008761772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8531,992,143 - 32,136,878 (+)NCBI
mRatBN7.2527,194,853 - 27,338,070 (+)NCBI
Rnor_6.0527,292,870 - 27,440,802 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110219   ⟹   XP_038966147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8532,099,863 - 32,136,878 (+)NCBI
mRatBN7.2527,302,596 - 27,338,070 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001102127   ⟸   NM_001108657
- UniProtKB: D3ZWZ8 (UniProtKB/TrEMBL),   A6II90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237963   ⟸   XM_006237901
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0G0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237966   ⟸   XM_006237904
- Peptide Label: isoform X3
- UniProtKB: A0A8I6G5L4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237965   ⟸   XM_006237903
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AB42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761772   ⟸   XM_008763550
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K0G0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761770   ⟸   XM_008763548
- Peptide Label: isoform X4
- UniProtKB: A6II91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071431   ⟸   ENSRNOT00000078102
RefSeq Acc Id: ENSRNOP00000063830   ⟸   ENSRNOT00000066191
RefSeq Acc Id: XP_038966147   ⟸   XM_039110219
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000090913   ⟸   ENSRNOT00000094571
RefSeq Acc Id: ENSRNOP00000081192   ⟸   ENSRNOT00000111262
Protein Domains
MYND-type   TAFH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K0G0-F1-model_v2 AlphaFold A0A0G2K0G0 1-604 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305490 AgrOrtholog
BioCyc Gene G2FUF-41902 BioCyc
Ensembl Genes ENSRNOG00000005673 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066191 ENTREZGENE
  ENSRNOT00000066191.2 UniProtKB/TrEMBL
  ENSRNOT00000078102.2 UniProtKB/TrEMBL
  ENSRNOT00000094571.1 UniProtKB/TrEMBL
  ENSRNOT00000111262.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1110 UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/TrEMBL
  6.10.250.230 UniProtKB/TrEMBL
InterPro ETO UniProtKB/TrEMBL
  MTG8 UniProtKB/TrEMBL
  NHR2 UniProtKB/TrEMBL
  TAFH/NHR1_dom_sf UniProtKB/TrEMBL
  TAFH_NHR1 UniProtKB/TrEMBL
  Znf_MYND UniProtKB/TrEMBL
KEGG Report rno:362489 UniProtKB/TrEMBL
NCBI Gene 362489 ENTREZGENE
PANTHER PTHR10379 UniProtKB/TrEMBL
  PTHR10379:SF5 UniProtKB/TrEMBL
Pfam NHR2 UniProtKB/TrEMBL
  TAFH UniProtKB/TrEMBL
  zf-MYND UniProtKB/TrEMBL
PhenoGen Runx1t1 PhenoGen
PRINTS ETOFAMILY UniProtKB/TrEMBL
  MTG8PROTEIN UniProtKB/TrEMBL
PROSITE TAFH UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/TrEMBL
  ZF_MYND_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005673 RatGTEx
SMART TAFH UniProtKB/TrEMBL
Superfamily-SCOP HIT/MYND zinc finger-like UniProtKB/TrEMBL
  SSF158553 UniProtKB/TrEMBL
UniProt A0A0G2K0G0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AB42 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5L4 ENTREZGENE, UniProtKB/TrEMBL
  A6II90 ENTREZGENE, UniProtKB/TrEMBL
  A6II91 ENTREZGENE, UniProtKB/TrEMBL
  D3ZWZ8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Runx1t1  RUNX1 partner transcriptional co-repressor 1  Runx1t1  RUNX1 translocation partner 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-29 Runx1t1  RUNX1 translocation partner 1  Runx1t1  runt-related transcription factor 1; translocated to, 1 (cyclin D-related)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Runx1t1  runt-related transcription factor 1; translocated to, 1 (cyclin D-related)  Cbfa2t1_predicted  CBFA2T1 identified gene homolog (human) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cbfa2t1_predicted  CBFA2T1 identified gene homolog (human) (predicted)    core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related (predicted)  Name updated 1299863 APPROVED
2005-01-12 Cbfa2t1_predicted  core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related (predicted)      Symbol and Name status set to approved 70820 APPROVED