Runx1t1 (RUNX1 partner transcriptional co-repressor 1) - Rat Genome Database

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Gene: Runx1t1 (RUNX1 partner transcriptional co-repressor 1) Heterocephalus glaber
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Symbol: Runx1t1
Name: RUNX1 partner transcriptional co-repressor 1
RGD ID: 18901232
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor binding (ortholog); identical protein binding (ortholog); INVOLVED IN fat cell differentiation (ortholog); negative regulation of fat cell differentiation (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nuclear matrix (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Protein CBFA2T1; RUNX1 translocation partner 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624744783 - 63,720 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Runx1t1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624744783 - 63,720 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RUNX1T1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38891,954,967 - 92,103,385 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl891,954,972 - 92,103,385 (-)EnsemblGRCh38hg38GRCh38
GRCh37892,967,195 - 93,115,613 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36893,040,328 - 93,176,619 (-)NCBINCBI36Build 36hg18NCBI36
Build 34893,040,327 - 93,144,367NCBI
Celera889,157,513 - 89,293,797 (-)NCBICelera
Cytogenetic Map8q21.3NCBI
HuRef888,174,218 - 88,322,535 (-)NCBIHuRef
CHM1_1893,007,519 - 93,155,728 (-)NCBICHM1_1
T2T-CHM13v2.0893,080,060 - 93,228,496 (-)NCBIT2T-CHM13v2.0
Runx1t1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39413,742,628 - 13,895,056 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl413,743,436 - 13,893,649 (+)EnsemblGRCm39 Ensembl
GRCm38413,742,628 - 13,895,056 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl413,743,436 - 13,893,649 (+)EnsemblGRCm38mm10GRCm38
MGSCv37413,670,449 - 13,820,796 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36413,711,929 - 13,818,264 (+)NCBIMGSCv36mm8
Celera413,520,441 - 13,687,612 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map45.88NCBI
Runx1t1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8531,984,946 - 32,136,878 (+)NCBIGRCr8
mRatBN7.2527,187,674 - 27,338,070 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl527,187,551 - 27,335,592 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx529,354,513 - 29,460,385 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0530,947,153 - 31,053,031 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0530,907,305 - 31,013,180 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0527,284,921 - 27,440,802 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl527,312,928 - 27,442,841 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0531,976,957 - 32,132,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4528,230,322 - 28,338,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1528,188,640 - 28,338,441 (+)NCBI
Celera526,502,150 - 26,607,942 (+)NCBICelera
Cytogenetic Map5q13NCBI
Runx1t1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554178,580,363 - 8,721,416 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554178,580,355 - 8,714,267 (-)NCBIChiLan1.0ChiLan1.0
RUNX1T1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27109,297,517 - 109,443,961 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1884,836,338 - 84,982,863 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0888,588,560 - 88,736,614 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1890,538,965 - 90,686,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl890,538,965 - 90,686,689 (-)Ensemblpanpan1.1panPan2
RUNX1T1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12937,156,861 - 37,289,934 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2937,158,659 - 37,297,879 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2937,305,761 - 37,440,000 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02937,355,710 - 37,490,023 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2937,357,901 - 37,498,074 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12937,374,916 - 37,509,114 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02937,356,296 - 37,490,752 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02937,796,907 - 37,931,529 (-)NCBIUU_Cfam_GSD_1.0
Runx1t1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530342,278,379 - 42,410,876 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365445,383,350 - 5,522,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365445,381,829 - 5,514,364 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUNX1T1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl444,599,760 - 44,743,418 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1444,600,292 - 44,745,954 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2448,029,947 - 48,172,694 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RUNX1T1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1886,984,638 - 87,127,648 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl886,988,366 - 87,090,875 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603953,720,972 - 53,868,048 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: XM_004842167   ⟹   XP_004842224
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624744783 - 63,720 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004842224 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB17321 (Get FASTA)   NCBI Sequence Viewer  
  JAN96908 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004842224   ⟸   XM_004842167
- UniProtKB: A0A0P6J3E8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Gene3D-CATH 1.20.120.1110 UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/TrEMBL
  6.10.250.230 UniProtKB/TrEMBL
InterPro CBFA2T1 UniProtKB/TrEMBL
  CBFA2T1/2/3 UniProtKB/TrEMBL
  NHR2 UniProtKB/TrEMBL
  TAFH/NHR1_dom_sf UniProtKB/TrEMBL
  TAFH_NHR1 UniProtKB/TrEMBL
  Znf_MYND UniProtKB/TrEMBL
NCBI Gene Runx1t1 ENTREZGENE
PANTHER PTHR10379 UniProtKB/TrEMBL
  PTHR10379:SF5 UniProtKB/TrEMBL
Pfam NHR2 UniProtKB/TrEMBL
  TAFH UniProtKB/TrEMBL
  zf-MYND UniProtKB/TrEMBL
PRINTS ETOFAMILY UniProtKB/TrEMBL
  MTG8PROTEIN UniProtKB/TrEMBL
PROSITE TAFH UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/TrEMBL
  ZF_MYND_2 UniProtKB/TrEMBL
SMART TAFH UniProtKB/TrEMBL
Superfamily-SCOP HIT/MYND zinc finger-like UniProtKB/TrEMBL
  SSF158553 UniProtKB/TrEMBL
UniProt A0A0P6J3E8 ENTREZGENE, UniProtKB/TrEMBL